Clinical trials: Soft Tissue Atrophy
Gingival Recession
A New Therapeutic Approach for Root Coverage
Different surgical techniques have been proposed for root coverage, showing varying results especially in areas of deep recessions.
- Trial name
- NCT01143610
- Testing
- Newly forming bone technique for root coverage, Subepithelial connective tissue graft for root coverage.
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Recession, Gingival
Effect of Two Methods of Soft Tissue Augmentation for Socket Closure on Soft Tissue Landmarks and Ridge Dimensions
To evaluate the effect of Connective Tissue Graft and Pediculated-Connective Tissue Graft for extraction socket closure on soft tissue landmarks and ridge dimensions.
- Trial name
- NCT05342649
- Testing
- P-CTG, CTG
- Where
- India
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- SVS Institute of Dental Sciences
Post-osseointegration Biological Failure of Dental Implant, Alveolar Bone Loss
The Influence of Mucosal Tissue Thickness on Soft and Hard Tissue Changes Around Implants
Crestal bone and soft tissue stability around implants is an important issue in implant dentistry. Initial vertical mucosal tissue thickness was shown to be one of the factors having impact on bone stability.
- Trial name
- NCT02580721
- Testing
- Dentsply Astra Tech Implant System EV
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Alveolar Bone Loss
Clinical, Radiographical, Histological Evaluation and Blood Flow Analysis of Alveolar Ridge Preservation
With alveolar ridge preservation (ARP) ridge resorption following extraction may be reduced. Several materials and techniques have been advocated for ARP.
- Trial name
- NCT05674331
- Testing
- Extraction site development technique, autogenous tooth bone graft, Socket seal technique
- Where
- Hungary
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Gingival Recession
Assessment of The Accuracy of Complete Crown 3D Superimposition Technique Relative to The Gold Standard Technique for Digital Quantification of Volumetric Soft Tissue Changes in The Esthetic Zone
The aim of this study is to assess the precision of the complete crown technique employed for the superimposition of 3D models, specifically in the quantitative volumetric evaluation of gingival tissues.
- Trial name
- NCT06457672
- Testing
- Group I, Group II
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Recession, Gingival
Soft Tissue Augmentation Around Immediate Implants In The Esthetic Zone
Following tooth loss, a considerable reduction in hard- and soft-tissue volume can be expected (Tan WL, et al., 2012), (AraujoMG, et al., 2015).
- Trial name
- NCT03802370
- Testing
- connective tissue grafting by Dome Technique
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Inclined Atrophy of the Distal Mandible, Socket Like Atrophy of the Aesthetic Zone
PEERS Multicenter Osseospeed TM TX Profile Implant: German Astra Soft Tissue (GAST) Maintenance Study
The open, prospective, non-controlled observational study is designed to provide information on the short-, medium- and long-term clinical performance of the Astra Tech OsseospeedTM implant surface in combination with a special…
- Trial name
- GAST (NCT01400321)
- Where
- 28 sites in Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Atrophy of Gingiva
Volumetric Evaluation of Gingival Augmentation Around Dental Implants
The goal of this observational prospective study is to objectively assess the dimensional (volume \& linear variance) and clinical changes of vestibular gingival soft tissues upon treatment with laser-aided pouch roll…
- Trial name
- NCT06057363
- Testing
- volumetric evaluation of gingival augmentation around dental implants
- Where
- Italy
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Odontostomatologic Laser Therapy Center, Florence, Italy
Soft Tissue Atrophy
Peri-Implant Soft Tissue Augmentation Using a Free Connective Tissue Graft With an Epithelial Collar
A prospective randomized interventional clinical trial (RCT) with a parallel-group design is planned. The study sample will include 32 patients randomly allocated into two groups according to the surgical intervention performed.
- Trial name
- NCT07626866
- Testing
- Free connective tissue graft without an epithelial collar, Free connective tissue graft with epithelial collar
- Where
- Russia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Gingival Atrophy
Soft Tissue Augmentation Around Dental Implant
Patients were randomly distributed into two groups (G1 and G2), all patients were treated by a submerged dental implant protocol and free gingival graft (FGG) harvested from the palate as follows: Group 1 (G1), received the FGG…
- Trial name
- NCT06238427
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Cleft Lip and Palate, Periodontal Pocket
Periodontal Changes Following Mid Maxillary Distraction
To evaluate the health status of the periodontium and dentition at the distraction osteogenesis site in CLP subjects using mid maxillary distraction (MMD).
- Conditions
- Cleft Lip and Palate, Periodontal Pocket, Attachment Loss, Periodontal
- Trial name
- NCT03686761
- Testing
- A Involvement with the osteotomy site of the surgery
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alexandria
Immediate Implants, Alveolar Bone Loss
Evaluation of Immediate Implant Placement In The Esthetic Zone Using the Bone Shielding Concept Versus Dual Zone Therapy
Immediate implant placement has proven to be a successful treatment procedure that is preferred by patients because of being less traumatic, more time-efficient.
- Conditions
- Immediate Implants, Alveolar Bone Loss, Dual Zone Technique, the Bone Shielding Concept
- Trial name
- NCT05381467
- Testing
- immediate implant placement with The Dual-Zone Therapeutic Concept, Immediate implant placement with the bone shielding concept
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Loss, Tooth Loss
Changes of Soft and Hard Tissues After Alveolar Ridge Preservation: Freeze-dried Bone Allograft vs. L-PRF Clot
A Clinical Trial to study the effectiveness between two, tooth socket grafting materials namely, Freeze Dried Bone Allograft (human derived bone particles) and Leukocytic-Platelet Rich Fibrin (the patient's own centrifuged…
- Trial name
- NCT03331185
- Testing
- Freeze Dried Bone Allograft, L-PRF clot
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Gingival Recession
Amnion Membrane Versus DFGG Using the Tunneling Technique in Management of Gingival Recession Defects.
Treatment of gingival recession is indicated mainly for esthetic reasons and keratinized tissue augmentation (Zucchelli and Mounssif, 2015).
- Trial name
- NCT06146855
- Testing
- Tunneling procedure with Amnion Membrane, Tunneling procedure with De-epithelialized Free Gingival Graft
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession
Root Biomodification With Citric Acid and Tetracycline Improves the Outcomes of Root Coverage
The aim of this study is to investigate the effects of the application of a citric acid + tetracycline gel solution during 90 or 180 seconds compared to no conditioning in the outcomes of treatment of Miller's class I or II…
- Trial name
- NCT02259543
- Testing
- Root conditioning with citric acid+tetracycline solution
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Bone Loss, Alveolar, Dental Implant Failed
Clinical and Radiographic Evaluation of Bone and Tissue Level Single Unit Implants: Two-piece Abutment Concept
Dental implants have become one of the most common treatments used for the rehabilitation of lost teeth. The success rate of dental implant treatment is quite high.
- Trial name
- NCT05592821
- Testing
- dental implant placement
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Berceste Guler
Recession, Gingival, Bone Loss in Jaw
L-PRF vs Connective Tissue With Customized Healing Abutment in Immediate Implant Placement
comparison between L-prf and connective tissue with dental implant
- Trial name
- NCT07102758
- Testing
- L-PRF with dental implant and customized healing abutment, Connective tissue with dental implant and customized healing abutment
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Atrophy of Breast
Efficacy and Safety Study of EVERA to Augment Small Breast
Expected Total Number of Subjects Level of significance, alfa 0.05 Power 0.80 Mean difference between two treatments is assumed 35 Standard Deviation is assumed 35. Follow-up loss is assumed 20% N=34(each group:17)
- Trial name
- NCT02009137
- Testing
- EVERA, ESTES
- Where
- South Korea
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Soft Tissue, Dental Implants
Xenogenic Bone Intentionally Left Exposed
The goal of this clinical trial is to compare, the effect of letting the xenogeneic bone graft exposed to the oral environment or seal off the graft with a collagen matrix.
- Conditions
- Soft Tissue, Dental Implants, Healing Wound
- Trial name
- NCT06191510
- Testing
- Bio-Oss Exposed, Mucograft Exposed
- Where
- Brazil
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Gingival Recession, Plastic Surgery
Local Application of Hyaluronic Acid (HYADENT BG) With Free Soft Tissue Grafing Improves Treatment Outcomes.
A total of 24 healthy non-smoker patients requiring FGG recruited for the study. Subjects were equally and randomly assigned into two groups. Test group, local application of HYADENT BG on both donor and recipient sites.
- Trial name
- NCT04821804
- Testing
- Hyaluronic Acid (HYADENT BG)
- Where
- Jordan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology