Clinical trials: Soft Tissue Defect
Soft Tissue Defect
Evaluation of Geistlich Fibro-Gide® in Comparison to CTG for the Treatment Around Implants
This double blind, randomized, parallel study evaluates the non-inferiority of Geistlich Fibro-Gide® in comparison to connective tissue graft for soft tissue volume augmentation around dental implants
- Trial name
- NCT04703738
- Testing
- Soft tissue flap + Connective Tissue Graft, Soft tissue flap + Geistlich Fibro-Gide®
- Where
- 5 sites in United States
- Volunteers
- 60 people
- Sponsor
- Geistlich Pharma AG
Wound of Skin, Ulcers
TrueLok Elevate PMCF Study
The TrueLok Elevate Transverse Bone Transport System is a modular external fixation device designed for transverse bone transport.
- Conditions
- Wound of Skin, Ulcers, Soft Tissue Defect
- Trial name
- NCT07079774
- Testing
- Transverse Bone Transport System
- Where
- 14 sites in Germany, Italy and 4 more
- Volunteers
- 153 people
- Sponsor
- Orthofix s.r.l.
Reconstruction of Upper Body Soft Tissue Defects
Reconstruction by Thoracodorsal Artery Perforator Flap in Patients With Upper Body Soft Tissue Defects
evaluation of versatility and reliability of thoracodorsal artery perforator flap by assessment of recipient site reach
- Trial name
- NCT07734337
- Testing
- Reconstruction
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Soft Tissue, Soft Tissue Defects
First-in-Human Safety Study for Fractomer™ Biomatrix
The goal of this clinical trial is to evaluate the safety of implanting a new medical device (Fractomer™ Biomatrix) in healthy volunteers.
- Conditions
- Soft Tissue, Soft Tissue Defects, Subcutaneous Injection
- Trial name
- NCT07151638
- Testing
- Implantation (injection) of a new biomatrix for soft tissue support.
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- inSoma Bio, Inc.
Soft Tissue Defects, Soft Tissue Wounds
Combined OFM and Vacuum-assisted Therapy for Expedited Regeneration Over Structures
Demonstrate faster tissue coverage of exposed structures using OFM in combination with negative pressure wound therapy (NPWT), versus NPWT alone
- Conditions
- Soft Tissue Defects, Soft Tissue Wounds, Traumatic Soft Tissue Defect
- Trial name
- COVER (NCT07385313)
- Testing
- Myriad™ applied in conjunction with NPWT, NPWT Alone
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Aroa Biosurgery Limited
Zygomatic Implants, Atrophic Maxilla
Buccal Fat Pad vs. Palatal Rotation Scarf Grafts for Soft Tissue Management Around Zygomatic Implants
Over the past 20 years, the demand for oral rehabilitation among edentulous patients has steadily increased. Traditionally, individuals with edentulous maxillae were treated using removable complete dentures.
- Conditions
- Zygomatic Implants, Atrophic Maxilla, Soft Tissue Defect, Soft Tissue Healing
- Trial name
- RCT BFP ZAGA (NCT06968780)
- Testing
- Buccal Fat Pad, Palatal Rotation Scarf Graft
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Cairo University
Post Traumatic Soft Tissue Defects That Could be Reached by Pedicled Anterolateral Thigh Flap, Post Tumor Excision Soft Tissue Defects
Reliability and Versatility of Pedicled Anterolateral Thigh Flap in Reconstruction of Soft Tissue Defects
a prospective case series study for evaluation of the reliability and versatility of pedicled anterolateral thigh flap in the reconstruction of soft tissue defects as regards flap survival and complications, donor site morbidity…
- Conditions
- Post Traumatic Soft Tissue Defects That Could be Reached by Pedicled Anterolateral Thigh Flap, Post Tumor Excision Soft Tissue Defects, Post Debridement Soft Tissue Defects
- Trial name
- NCT06841419
- Testing
- surgical reconstruction of a soft tissue defects by a pedicled flap
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Soft Tissue Defects, Perforator Flap
Perforator Pedicled V-Y Advanced Flaps for Coverage in the Lower Limbs
Repair of soft tissue defects with hardware exposing in the lower limbs was considered as a severe challenge for plastic surgeons in reconstructive surgery.
- Trial name
- NCT06885450
- Testing
- Perforator Pedicled Flaps
- Where
- China
- Volunteers
- 24 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
Trauma Patients With Soft Tissue Defects
Posterior Tibial Artery Perforator-Pedicled Propeller Flaps in Reconstruction
Soft tissue defects in the lower leg remain a challenge for surgeons due to frequent bone exposure and paucity of soft tissues. The goal in this study was to evaluate the surgical technique and clinical significance of posterior…
- Trial name
- NCT06885892
- Testing
- Posterior Tibial Artery Perforator-Pedicled Propeller Flaps, Perforator-Pedicled Propeller Flaps
- Where
- China
- Volunteers
- 14 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
SOFT TISSUE DEFECTS
Outcomes and Clinical Applications of Thin Free Flaps for Soft Tissue Defects
Flap coverage is often required to achieve primary wound closure and to achieve a good functional result. Free flap has gain popularity over random flap in soft tissue reconstruction to achive maximal cosmetic and functional…
- Trial name
- NCT05828771
- Testing
- THIN FREE FLAP
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Sohag University
Coverage of Soft Tissue Defects
Perforator Mapping and Optimizing Design of the Lateral Arm Flap
The goal of this clinical trial is to optimize the design of lateral arm flap. Colored duplex will be done for all Participants and compared to intra operative findings.
- Trial name
- NCT05718635
- Testing
- coloured duplex, supra facial dissection
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aswan University
Reconstruction of Head Soft Tissue Defects, Reconstruction of Neck Soft Tissue Defects
Reliability and Versatility of Supraclavicular Artery Flap in Reconstruction of Head and Neck Soft Tissue Defects
This is a case series study conducted at plastic surgery department Sohag University including 20 patients The aim of this thesis is to evaluate reliability and versatility of Supraclavicular artery flap in the reconstruction of…
- Trial name
- NCT05727150
- Testing
- Reconstruction of Soft tissue defects of head and neck by Supraclavicular artery flap
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Soft Tissue Defect of Digit, Nerve Injury
A Comparison of the Littler Flap With the Bipedicled Nerve Flap
A retrospective study is conducted with 59 patients who has a combination of soft tissue and digital nerve defects following trauma treated using the Littler flap or bipedicle nerve flap.Patients are divided into two groups.
- Trial name
- NCT03701685
- Testing
- nerve flap
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Tangshan
Abnormally Healing Wounds, Scars
Safety of Adipose-Derived Stem Cell Stromal Vascular Fraction
A single-arm, open-labeled, single-center, descriptive and exploratory safety trial using ADSC-SVF-002. ADSC-SVF-002 is an autologous adipose derived stem cell (ADSC)-containing stromal vascular fraction (SVF) obtained from…
- Conditions
- Abnormally Healing Wounds, Scars, Soft Tissue Defects
- Trial name
- NCT02590042
- Testing
- ADSC-SVF-002
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- AdiSave Inc.
Dental Implant Soft Tissue Defects in the Anterior Maxilla
A Randomized Control Trial Testing Connective Tissue Grafts vs. Allograft on Dental Implants
This randomized controlled clinical pilot trial compared the efficacy of two soft tissue grafting methods for correcting esthetic discrepancies associated with non-molar implants in the maxilla.
- Trial name
- NCT01934530
- Testing
- Soft Tissue Grafting
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Soft Tissue Defect of Digit
Sensory Reconstruction of the Digits
A retrospective study is conducted with 151 patients who has a soft tissue defect of digit treated with the sensate flaps from February 2005 to March 2014.
- Trial name
- NCT02695485
- Testing
- innervated sensate flap
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Tangshan
Soft Tissue Defect, Sensory Reconstruction of Digits
The Dorsal Homodigital Island Flap Based on the Dorsal Branch of the Digital Artery: A Review of 171 Cases
Soft tissue reconstruction in the finger continues to evolve. The dorsum of the finger is a reliable flap donor site in reconstructive hand surgery because of its similar quality to the original.
- Conditions
- Soft Tissue Defect, Sensory Reconstruction of Digits, Multiple Digital Defects
- Trial name
- NCT01871103
- Testing
- The dorsal homodigital island flap
- Where
- China
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Tangshan
Soft Tissue Defect of the Finger
A Comparison of Dorsal Branch of the Digital Nerve Versus Dorsal Digital Nerve for Finger Pulp Reconstruction
As the donor nerve attached with the flap, the dorsal branch of the digital nerve and the dorsal digital nerve is commonly used for finger pulp reconstruction.This study compares two donor nerves: the dorsal branch of the digital…
- Trial name
- NCT01826539
- Testing
- flap includes a donor nerve
- Where
- China
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Tangshan
Soft Tissue Loss With Nerve Defect
Treatment of Soft Tissue Loss With Nerve Defect in the Finger Using the Boomerang Nerve Flap
Soft tissue loss with proper digital nerve (PDN) defect in the finger results in sensory loss of the finger pulp. Reconstruction of these complex soft tissue defects continues to be a challenge problem.
- Trial name
- NCT01629602
- Testing
- the Boomerang Nerve Flap
- Volunteers
- 49 people
- Sponsor
- The Second Hospital of Tangshan
Soft Tissue Defect
Clinical Experience With a Tensor Fasciae Latae Perforator Flap Based on Septocutaneous Perforators
The purpose of this study is to evaluate the possible harvest of a tensor fasciae latae flap based on septocutaneous perforators.This study should further confirm our data from an anatomical study concerning location…
- Trial name
- NCT01136044
- Testing
- septocutaneous perforator flap
- Where
- Austria
- Volunteers
- 14 people
- Sponsor
- Medical University of Graz