Clinical trials: Soft Tissue Grafting
Soft Tissue Atrophy, Mucogingival Deformity on Edentulous Ridge
Behavioral Comparison of Three Different Graft Materials to Increase Soft Tissue Thickness Around Dental Implants.
The purpose of the study is to compare soft tissue volume changes in terms of volume gain and stability around dental implants and PROMS in cases where a sub-epithelial connective tissue graft (SCTG) from the palate, Porcine…
- Conditions
- Soft Tissue Atrophy, Mucogingival Deformity on Edentulous Ridge, Edentulous Alveolar Ridge
- Trial name
- NCT04766255
- Testing
- Soft Tissue graft augmentation, Implant Placement
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Dental Implant
Effect of Bone Graft Material ON Peri-Implant Phenotype .
This prospective three-arm controlled interventional clinical study evaluates the effects of NanoBone alone and NanoBone combined with platelet-rich fibrin (PRF) on peri-implant hard and soft tissue phenotype after dental implant…
- Trial name
- NCT07835451
- Testing
- Dental implant placement, NanoBone, NanoBone sticky bone plus CGF/PRF membrane
- Where
- Iraq
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Peri-implant Mucositis, Soft Tissue Inflammation
Effect of Free Gingival Grafting on Peri-implant Health
The goal of this randomized clinical study is to investigate the impact of soft tissue phenotype modification following free gingival grafting (FGG) in addition to the non-surgical mechanical therapy of peri-implant mucositis…
- Trial name
- NCT06392256
- Testing
- Non surgical therapy, Free gingival Grafting
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Gazi University
Peri-Implantitis
The Adjunctive Effect of Soft Tissue Augmentation Procedures of Moderate-severe Peri-implantitis
The key objective of the study is to compare the effects of soft tissue augmentation using a volume stable collagen matrix or autogenous connective tissue graft or no soft tissue augmentation in addition to bone…
- Trial name
- NCT05415111
- Testing
- Subepithelial connective tissue, Volume stable Collagen Matrix, No soft tissue augmentation
- Where
- 3 sites in Germany, Singapore and 1 more
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Nadja Naenni
Alveolar Ridge Augmentation, Connective Tissue
Ridge Preservation Using Different Techniques
Soft tissue contour and radiographic evaluation of alveolar ridge preservation using different techniques Background: Following tooth extraction, the alveolar ridge undergoes an inevitable remodeling process which influences…
- Conditions
- Alveolar Ridge Augmentation, Connective Tissue, Tooth Extraction, Membranes; Retained
- Trial name
- NCT05892016
- Testing
- Alveolar ridge preservation
- Where
- Taiwan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Buccal Soft Tissue Profile (BSP)
Connective Tissue Graft Versus Collagen Matrix
Patients in need of a single implant in the premaxilla and presenting with a horizontal buccal soft tissue defect at the single tooth gap will be invited to participate in a multicenter RCT.
- Trial name
- BC-5303 (NCT04210596)
- Testing
- Soft tissue augmentation at the buccal aspect of single implants
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Ghent
Implant Complication
Vertical Soft Tissue Augmentation With CTG vs ADM
The study aims at comparing two different approaches for vertical soft tissue augmentation at implant sites exhibiting soft tissue dehiscences: autogenous connective tissue graft vs acellular dermal matrix + enamel matrix…
- Trial name
- NCT05729607
- Testing
- Vertical soft tissue augmentation
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Hopeless Tooth in Esthetic Zone, Loss of Soft and Hard Tissue Around Implant
Peri-implant Tissue Changes Using Dual Zone Concept With Connective Tissue Graft Versus Concentrated Growth Factor
Tooth extraction not only alters the bony architecture of the alveolar ridge, but it also has an impact on the surrounding soft tissues.
- Conditions
- Hopeless Tooth in Esthetic Zone, Loss of Soft and Hard Tissue Around Implant, Immediate Implant Placement
- Trial name
- NCT06728696
- Testing
- Immediate implant with with dual zone technique using concentrated growth factor graft., Immediate implant with dual zone technique using connective tissue graft.
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Mucogingival Defects, Pontic Site Development
Pontic Site Development With or Without Fixed Partial Denture
This study aims to evaluate the effectiveness of soft tissue augmentation using connective tissue graft (CTG) in pontic site defects.
- Conditions
- Mucogingival Defects, Pontic Site Development, Keratinized Tissue Deficiency, Connective Tissue Graft
- Trial name
- Pontic Site (NCT07535060)
- Testing
- Connective Tissue Graft (CTG)
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Acellular Dermal Matrix, Bone Grafting
Evaluating the Barrier Function, Regenerative Capacity, and Soft Tissue Outcomes of Acellular Dermal Matrix
This investigator-initiated study will compare ADM and resorbable cross-linked collagen membrane barriers for guided bone regeneration at atrophic lateral ridge augmentation sites.
- Conditions
- Acellular Dermal Matrix, Bone Grafting, Soft Tissue Grafting
- Trial name
- NCT07613047
- Testing
- Guided Bone Regeneration with ADM (AlloDerm) as a barrier, Guided Bone Regeneration with Resorbable Crosslinked Collagen Matrix (Mem-Lok) as a barrier
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Horizontally Deficient Alveolar Ridges, Hard and Soft Tissue Augmentation During Delayed Implant Placement
Effectiveness of Subepithelial Connective Tissue Graft as an Autogenous Barrier Membrane for Hard and Soft Tissue Augmentation in Horizontally Deficient Ridges During Delayed Implant Placement
This study evaluates the clinical effectiveness of using a patient's own subepithelial connective tissue graft as a natural barrier membrane during simultaneous hard and soft tissue augmentation in areas of the jawbone with…
- Trial name
- CBCT-GBR-SECTG (NCT07861724)
- Testing
- Subepithelial Connective Tissue Graft as an Autogenous Barrier Membrane for Hard and Soft Tissue Augmentation in Horizontally Deficient Ridges during delayed implant placement
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Recession, Gingival
Palatal Volumetric Change Analysis Following Connective Tissue Graft With and Without Donor Site Augmentation
The goal of this randomized clinical trial is to compare whether soft tissue augmentation placed in the donor site following a gum graft harvesting leads to volumetric changes compared to non-augmented sites in the palate.
- Trial name
- NCT05961566
- Testing
- Use of collagen matrix after subepithelial connective tissue graft harvest
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hailey Bivens
Gingival Recession, Generalized, Graft Reaction
The Healing of Soft Tissue Augmentation by Acellular Dermal Matrix and Autogenous Subepithelial Connective Tissue Graft
The study team proposes to prospectively compare the healing outcomes of autogenous soft tissue connective tissue graft (CTG) and Acellular dermis matrix (ADM) in a split-mouth design study for patients requiring modification of…
- Trial name
- NCT03954028
- Testing
- Gingival Punch Biopsy after healing of Gingival Soft Tissue Augmentation
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Craniofacial Microsomia
Clinical Trial of Fat Grafts Supplemented With Adipose-derived Regenerative Cells
Although first reports of the clinical use of adipose-derived regenerative cells (ADRC) suggest that this approach may be feasible and effective for soft tissue augmentation, there is a lack of randomized, controlled clinical…
- Trial name
- NCT01674439
- Testing
- Supplementation of ADRC, Without supplementation of ADRC
- Where
- Brazil
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Missing Teeth
Assessment of Hard and Soft Tissue Changes Following XCM Versus FGG Simultaneous With Delayed Dental Implant Placement
Teeth loss are usually associated with alterations of extraction sockets result in obviously absorbed alveolar ridges and are often accompanied with soft tissue atrophy such as narrow keratinized tissue and a shallow vestibule.
- Trial name
- NCT07080177
- Testing
- Free gingival graft simultaneous with delayed implant placement, Xenogeneic collagen matrix simultaneous with delayed implant placement
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Implants
Peri-implant Soft Tissue Changes at Small Buccal Dehiscences
This study was designed to assess peri-implant soft tissue health, volume and marginal stability at implants sites which presented small buccal bone dehiscences (<3mm evaluated in a vertical direction) at the time of insertion.
- Trial name
- NCT07501715
- Testing
- Connective tissue graft, horizontal guided bone regeneration
- Where
- Italy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Cleft Lip and Palate
Alveolar Cleft Hard- and Soft Tissue Reconstruction With an Autogenous Tooth Derived Particulate Graft
The present study aims at clinical and radiographic evaluation of the safety and efficacy of Bonmaker ATB powder combined with a novel split thickness papilla curtain flap in the treatment of alveolar cleft defects.
- Trial name
- NCT05971914
- Testing
- Autogenous tooth derived particulate graft and a novel split thickness papilla curtain flap
- Where
- Hungary
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Extraction Sites After Removal and Bone Replacement Grafting at Extraction Sockets of Dentally Hopeless Single-rooted Teeth
To Compare Post-Extraction Use of a Novel Ethylenediaminetetraacetic Acid (EDTA) Post-operative Mouth Rinse and Daily Use EDTA Mouth Rinse and Standard 0.12% Chlorhexidine (CHX) Post-operative Mouth Rinse and Daily Use Essential Oil (EO) Mouth Rinse.
This study will compare commercially available, commonly used mouth rinses (0.12% chlorhexidine (CHX) vs. Ethylenediaminetetraacetic acid (EDTA)) for immediate post-operative and daily antiseptic use after tooth extraction and…
- Trial name
- NCT07191262
- Testing
- 0.12% CHX and Essential Oil mouthrinse, 2.6% EDTA and 0.2% EDTA mouth rinse
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Gingival Recession
Root Biomodification With Citric Acid and Tetracycline Improves the Outcomes of Root Coverage
The aim of this study is to investigate the effects of the application of a citric acid + tetracycline gel solution during 90 or 180 seconds compared to no conditioning in the outcomes of treatment of Miller's class I or II…
- Trial name
- NCT02259543
- Testing
- Root conditioning with citric acid+tetracycline solution
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Alveolar Bone Loss
Pontic Site Development Using Soft Tissue Augmentation
in patients with vertical or horizontal defective of there ridge it is difficult to have prosthetic restoration with natural appearance emetating and simulating the adjacent abutment emergence profile so this study aims to…
- Trial name
- NCT03834649
- Testing
- partially de-epithelized connective tissue graft, Mucograft
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Nouran Abdulla Mater,MD