Clinical trials: Soft Tissue Grafting
Alveolar Bone Loss
Clinical, Radiographical, Histological Evaluation and Blood Flow Analysis of Alveolar Ridge Preservation
With alveolar ridge preservation (ARP) ridge resorption following extraction may be reduced. Several materials and techniques have been advocated for ARP.
- Trial name
- NCT05674331
- Testing
- Extraction site development technique, autogenous tooth bone graft, Socket seal technique
- Where
- Hungary
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Soft Tissue Augmentation
The Use of a Porcine Collagen Matrix for the Prevention of Buccal Bone Wall Resorption During Implant Placement in the Aesthetic Zone.
Aim: To provide a comparative assessment of the clinical and radiographic effect of porcine collagen matrix when placed buccally at the time of single implant placement in the aesthetic zone vs autogenous connective tissue graft…
- Trial name
- NCT06622759
- Testing
- CTG, Collagen Matrix, Control group
- Where
- Greece
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Dental Implants
Peri-implant Soft Tissue Volume Changes at Small Buccal Dehiscences
This study was designed to assess peri-implant soft tissue health, volume and marginal stability at implants sites which presented small buccal bone dehiscences (<3mm evaluated in a vertical direction) at the time of insertion.
- Trial name
- NCT05466006
- Testing
- Soft tissue augmentation with subepithelial connective tissue graft (SCTG), Soft tissue augmentation with xenogenic volume stable collagen matrix (VCXM)
- Where
- Italy
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Localized Gingival Recession
Use of a Collagen Membrane for Soft Tissue Grafting
Is PriMatrix wound dressing capable of regenerating gum tissue inside the mouth?
- Trial name
- NCT02206009
- Testing
- Collagen Membrane
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Lauren M. F. Syrowik
Tooth Loss, Recession, Gingival
Soft Tissue Volume Gain and Stability Comparing Palate and Tuberosity
The goal of this study is to compare clinical and histologically the soft tissue changes in terms of volume gain and stability around dental implants in cases where a subepithelial connective tissue graft from the palate or from…
- Trial name
- NCT03090906
- Testing
- Soft tissue augmentation palate, Soft tissue augmentation tuberosity, Intraoral optical scan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Customized Healing Abutment Bone Grafts Connective Tissue Graft Immediate Implant Placement
Midfacial Gingival Margin Changes Following Immediate Implants.
Dimensional changes, including the loss of labial soft tissues and midfacial gingival recession, seem to be inevitable following immediate placement.
- Trial name
- NCT05975515
- Testing
- Connective tissue graft /Bone graft/ Customized HA
- Where
- Egypt
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cairo University
Patients With at Least Single Missing Anterior Tooth, Thin Gingival Biotype
Clinical Evaluation of Platelet Rich Fibrin Versus Subepithelial Connective Tissue Graft for Soft Tissue Augmentation
Soft tissue biotype is a critical factor for success of implant in the esthetic zone . Different soft tissue augmentation techniques have been employed to increase soft tissue thickness such as: autogenous grafts, allografts…
- Trial name
- NCT03219944
- Testing
- Platelet Rich Fibrin, sub epithelial connective tissue graft
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
Immediate Implant and Bone Graft
Clinical Evaluation of Soft Tissue Esthetics Around Immediate Implant Using Dual Zone Therapeutic Concept Versus Buccal Gap Fill to Bone Level
Immediate implant placement in the esthetic zone is very challenging procedure although it is documented as a promising procedure (Berglundh, Persson and Klinge, 2002)(Cosyn et al., 2011).
- Trial name
- NCT03768297
- Testing
- dual zone concept
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Peri-Implant Health, Peri-Implant Tissues
Comparison Between Free Gingival Graft and Palatal Pedicle Flap
Patients requiring KMW gain(mm) during uncovering surgery were included. Two surgical methods were compared: apically position flap with free gingival graft (FGG group) and the palatal pedicle flap with collagen matrix (PPF…
- Conditions
- Peri-Implant Health, Peri-Implant Tissues, Peri-implant Bone Level
- Trial name
- Pedicle (NCT06816680)
- Testing
- APF + FGG, PPF group
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Free Gingival Graft, Free Gingival Graft Volume Change
Tissue Augmentation Technique Using Free Gingival Graft Simultaneous With Posterior Mandibular Implant
Presence of keratinized tissue (KT) around dental implants, plays a crucial role in stability and health of peri-implant tissues.
- Conditions
- Free Gingival Graft, Free Gingival Graft Volume Change, Keratinized Tissue
- Trial name
- NCT06645925
- Testing
- One Step Protocol, Two Steps Protocol
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Misr International University
Soft Tissue Augmentation
Soft Tissue Evaluation Around Implants Using Prf or a Palatal Pedicle
Clinical Evaluation of Peri-Implant Soft Tissue Around Immediately Placed Implants Using PRF Membrane Versus The Palatal Pedicle Soft Tissue Graft: A Randomized Controlled Clinical Trial.
- Trial name
- NCT03224442
- Testing
- PRF, Palatal Pedicle
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bone Resorption
Timing of Soft Tissue Grafting Following Immediate Implant Placement
Patients undergoing single immediate implant placement (IIP) in the premaxilla will be invited to participate in this randomized controlled trial (RCT).
- Trial name
- NCT05537545
- Testing
- Soft tissue grafting
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Ghent
Immediate Implants Connective Tissue Graft
Hard and Soft Tissue Changes After Immediate Implant Placement Using Connective Tissue Graft With and Without Bone Grafting in the Esthetic Zone
Evaluation of soft and hard tissue changes after immediate implant placement with connective tissue graft and bone as a control group and connective tissue graft only as a test group.
- Trial name
- NCT06592079
- Testing
- Immediate implant and connective tissue graft, Immediate implant with connective tissue graft and bone graft
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
Punch Biopsy Wounds, Healing Times
Healing of Punch Graft Wounds. Comparative Study Between MariGen and Oasis: a Non-inferiority Study
The objective is to determine, if healing of punch biopsy wounds treated with the fish skin derived MariGen Wound dressing is non-inferior to healing with wounds treated with pig intestines derived Oasis Sheet wound dressing.
- Trial name
- NCT01917591
- Testing
- Punch biopsies treated with MariGen Wound ECM dressing, Punch biopsies treated with Oasis ECM dressing
- Where
- Iceland
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Kerecis Ltd.
Wound Healing
Effects of CGF and Collagen Fleece on Palatal Donor Site Healing: A Randomized Clinical Trial
This study investigated whether applying Concentrated Growth Factor (CGF) or Collagen Fleece (CF) to the palatal donor site after autogenous soft tissue graft harvesting could improve wound healing and reduce postoperative…
- Trial name
- PAL-HEAL (NCT07367165)
- Testing
- Concentrated Growth Factor (CGF), Collagen Fleece (CF), Collagen Sponge (Control)
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Inonu University
Dental Implantation, Peri-Implant Soft Tissue Deficiency
Volume-Stable Collagen Matrix vs. Connective Tissue Graft for Peri-Implant Soft Tissue Defects
Peri-implant soft-tissue defects will be treated with either a volume-stable collagen matrix (VCMX; test group) or an autogenous connective tissue graft (CTG; control group) following implant placement in patients with a single…
- Conditions
- Dental Implantation, Peri-Implant Soft Tissue Deficiency, Soft Tissue Augmentation
- Trial name
- NCT07782125
- Testing
- Connective tissue graft, Volume-stable collagen matrix
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ankara University
Free Gingival Graft, Soft Tissue Augmentation Around Dental Implants
Clinical Evaluation of a Modified Technique for Free Gingival Graft Stabilization Using Titanium Fixation Tacs Around Implants Versus Conventional Suturing Technique
The aim of this randomized, controlled, parallel-grouped, clinical trial is to evaluate the width of keratinized gingiva after free gingival graft stabilized by titanium fixation tacs compared to traditional suturing.
- Conditions
- Free Gingival Graft, Soft Tissue Augmentation Around Dental Implants, Inadequate Keratinized Tissue Around Dental Implants
- Trial name
- NCT07019428
- Testing
- Free gingival graft stabilized by Titanium fixation tacs, Free gingival graft stabilized by sutures
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Soft Tissue Thickness Arround Implants
Implants Placement with Simultaneous Soft Tissue Augmentation Using a Collagen Matrix Compared to Connective Tissue Graft: a Pilot Study
Background: To our knowledge, no study evaluated the use of VCMX at multiple implant sites and compared its efficacy and safety to a SCTG with the same dimensions.
- Trial name
- NCT06585813
- Testing
- dental implant, Fibrogide membrane, connective tissue graft
- Where
- Lebanon
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Bone Graft; Complications, Infection or Inflammation, Ridge Deficency
To Compare Different Soft Tissue Grafts at the Time of Lateral Ridge Augmentation Procedure.
This study will compare two commonly used soft tissue grafting techniques (connective tissue graft, CTG vs Acellular Dermal Matrix, ADM) to augment the soft tissue at the time of lateral ridge augmentation procedure.
- Conditions
- Bone Graft; Complications, Infection or Inflammation, Ridge Deficency, Dental Implant
- Trial name
- NCT03774888
- Testing
- Connective tissue graft at time of bone graft, Acellular Demal Matrix at time of bone graft, No soft tissue grafting at time of bone graft
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Soft Tissue Augmentation, Pontic Site Development
Pontic Site Soft Tissue Augmentation Using De-epithelized Connective Tissue Graft Versus Partially De-epithelized Connective Tissue Graft
a comparative study to evaluate the pontic site soft tissue augmentation by partially de-epithelized connective tissue graft versus completely de-epithelized connective tissue graft (both grafts harvested from the hard palate).
- Trial name
- NCT07434297
- Testing
- Intervention, Control
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts