Clinical trials: Soft Tissue Grafting
Alveolar Bone Loss
Localized Alveolar Ridge Augmentation With Space Maintenance Devices
The purpose of this research study is to determine whether this study treatment can improve the bone structure of the upper front part of the jaw in patients who are scheduled for surgery to have a dental implant(s) placed into…
- Trial name
- Ridge Mesh (NCT00991432)
- Testing
- INFUSE® Bone Graft
- Where
- 8 sites in United States
- Volunteers
- 10 people
- Sponsor
- Medtronic Spinal and Biologics
Soft Tissue Atrophy
Clinical and Histological Outcomes of Using Collagen Matrix or Soft Tissue Graft Around Implants
This was an interventional prospective randomized clinical trial (RCT) in parallel groups. The sample size is 35 patients who were randomly divided into two groups depending on the surgical intervention used.
- Trial name
- NCT05123898
- Testing
- Soft tissue augmentation
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Immediate Dental Implant Placement, Connective Tissue Graft
Immediate Implants in Front Teeth With Bone Loss: Regeneration and Temporary Crown in a Randomized Clinical Study
This clinical trial investigates the biological and clinical outcomes of immediate implant placement in aesthetic areas presenting with buccal bone dehiscence.
- Conditions
- Immediate Dental Implant Placement, Connective Tissue Graft, Connective Tissue Graft Harvesting, Soft Tissue Management in Subcrestal Dental Implants
- Trial name
- GBR / RCT (NCT07415486)
- Testing
- immediate implant placement with DBBM-C and connective tissue graft, immediate implant placement with DBBM-C with collagen membrane
- Volunteers
- 24 people
- Sponsor
- Universitat Internacional de Catalunya
Breast Cancer, Radiation Fibrosis
Autologous Fat Grafting in Radiated Soft Tissue Reconstruction
The purpose of this study is to observe the effect of autologous fat grafting on soft tissue reconstruction of the breast following radiation treatment.
- Conditions
- Breast Cancer, Radiation Fibrosis, Fat Grafting
- Trial name
- NCT05890196
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Chicago
Mucosal Erosion, Gingival Recession
Patient-reported Outcomes of Donor Site Healing Using Different Palatal Protection Techniques
This study has been initiated to evaluate the question, "What is the best way to protect the palate after a gum graft is removed?" The overall objective is to determine if there is a difference in PROMs of donor site healing…
- Trial name
- NCT06892496
- Testing
- Visual Analog scale (VAS) questionnaire, Vacuum-formed retainer (VFR) technique, 3-D printed acrylic resin stent (3DS) technique
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Virginia Commonwealth University
Immediate Temporization and Soft Tissue Augmentation Around Delayed Implants
Comparison of Peri Implant Soft Tissue Esthetics With Immediate Temporization With and Without Subepithelial Connective Tissue Graft
The aim of this study is to clinically evaluate peri-implant soft tissue esthetics around single delayed implants in the esthetic zone.
- Trial name
- NCT03770975
- Testing
- delayed implant with immediate provisionaliztion and soft tissue graft, delayed implant placement with immediate provisionalization
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Peri-implant Mucositis, Peri-Implantitis
Comparison of CTG and T-PRF on Peri-Implant Soft Tissue
The present study aimed to increase the thickness of the gingiva and prevent possible crestal bone resorption by placing the CTG or T-PRF membrane under the mucosa immediately after the implant treatment in individuals with thin…
- Conditions
- Peri-implant Mucositis, Peri-Implantitis, Thin Gingiva
- Trial name
- NCT04042194
- Testing
- Placement of Implants and Thickening Peri-Implant Mucosa with T-PRF, Placement of Implants and Thickening Peri-Implant Mucosa with CTG
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Soft Tissue Thickness Around Delayed Implants in Patients With Thin Gingival Phenotype
Effectiveness of Connective Tissue Graft With and Without Leukocyte Platelet Rich Fibrin on Peri-implant Soft Tissue Thickness Around Delayed Implants in Patients With Thin Gingival Phenotype: A Randomized Controlled Clinical Trial
A stable soft and hard tissues around Osseo-integrated implants are very crucial. Soft tissue thickness around implants is crucial as it prevents peri-implant bone loss and enhance the esthetic outcomes.
- Trial name
- NCT07368621
- Testing
- Connective tissue graft(CTG), Connective tissue graft (CTG) + leukocyte platelet-rich fibrin (L-PRF)
- Where
- Egypt
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Recession, Gingival
Palatal Volumetric Change Analysis Following Connective Tissue Graft With and Without Donor Site Augmentation
The goal of this randomized clinical trial is to compare whether soft tissue augmentation placed in the donor site following a gum graft harvesting leads to volumetric changes compared to non-augmented sites in the palate.
- Trial name
- NCT05961566
- Testing
- Use of collagen matrix after subepithelial connective tissue graft harvest
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hailey Bivens
Soft Tissue Mass
Soft Tissue Profile Following Socket Preservation With Platelet Rich Fibrin Versus Free Gingival Graft
Comparing socket preservation with Platelet -Rich Fibrin versus Free gingival graft.
- Trial name
- NCT03628170
- Testing
- platelet rich fibrin, Free gingival graft
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Localized Gingival Recession
Use of a Collagen Membrane for Soft Tissue Grafting
Is PriMatrix wound dressing capable of regenerating gum tissue inside the mouth?
- Trial name
- NCT02206009
- Testing
- Collagen Membrane
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Lauren M. F. Syrowik
Implant or Graft; Rejection
Implant Placement in Horizontally Deficient Maxillary Aesthetic Zone With Simultaneous Soft Tissue Augmentation
Tooth extraction in maxillary esthetic zone is accomplished with great dimensional changes of the alveolar ridge, different procedures have been tested to compensate these dimensional alteration, such as Hard bone augmentation…
- Trial name
- NCT05274256
- Testing
- implant placement with simultaneous soft tissue augmentation
- Where
- Egypt
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Cairo University
Wound Healing, Palatal Wound
The Effectiveness of Nano Bio Fusion Gingival Gel (NBF) on Wound Healing at the Palate (Donor Site) After Soft Tissue Graft Surgery Compared to Placebo Gel.
The goal of this clinical trial is to assess the effect of Nano-biofusion gingival gel (NBF) on wound healing at the palatal donor site following soft tissue graft surgery and compare it to placebo gel.
- Conditions
- Wound Healing, Palatal Wound, Donor Site Complication, Inflammatory Cytokines
- Trial name
- NCT07330154
- Testing
- Application of NBF gel after soft tissue graft surgery
- Where
- Jordan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Soft Tissue Infections, Gingival Recession
Clinical Effectiveness of Polymethoxy Flavones Solid Dispersion as a Dressing Material for Palatal Grafts Donor Sites
Free gingival grafting surgeries require palatal grafts harvesting from the patient own palates . The donor sites pain , infection and retarded healing by secondary intension are the complication .
- Trial name
- RCT (NCT05814003)
- Testing
- hydroxylate flavones solid dispersion application
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Soft Tissue Atrophy
Comparative Analysis Using the Collagen Matrix and Autogenous Graft: Clinical Course, Aesthetic Results
This was an interventional prospective randomized clinical trial (RCT) in parallel groups. The sample size is 32 patients who were randomly divided into two groups depending on the surgical intervention used.
- Trial name
- NCT05870774
- Testing
- Soft tissue augmentation with CTG, Soft tissue augmentation with CM
- Where
- Russia
- Volunteers
- 52 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Wounds and Injuries, Wound Infection
Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wounds and Injuries, Wound Infection, Facial Bones Fracture, Soft Tissue Injuries
- Trial name
- FTFDT2 (NCT03880188)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Alveolar Ridge Augmentation, Connective Tissue
Ridge Preservation Using Different Techniques
Soft tissue contour and radiographic evaluation of alveolar ridge preservation using different techniques Background: Following tooth extraction, the alveolar ridge undergoes an inevitable remodeling process which influences…
- Conditions
- Alveolar Ridge Augmentation, Connective Tissue, Tooth Extraction, Membranes; Retained
- Trial name
- NCT05892016
- Testing
- Alveolar ridge preservation
- Where
- Taiwan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Implant Complication
Vertical Soft Tissue Augmentation With CTG vs ADM
The study aims at comparing two different approaches for vertical soft tissue augmentation at implant sites exhibiting soft tissue dehiscences: autogenous connective tissue graft vs acellular dermal matrix + enamel matrix…
- Trial name
- NCT05729607
- Testing
- Vertical soft tissue augmentation
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Dupuytren's Disease
Efficacy of Aponeurectomy on the 2-year Recurrence Rate of Dupuytren's Disease
Dupuytren's disease is a frequent hereditary disease in Northern Europe. It is a degenerative disease affecting the palmar aponeurosis of the hand.
- Trial name
- REMEDY (NCT05067764)
- Testing
- Aponeurectomy with grafting, Aponeurectomy alone
- Where
- 2 sites in France
- Volunteers
- 172 people
- Sponsor
- Elsan
Dental Implants, Peri-Implant Tissues
CTG vs VCMX for Peri-implant Soft Tissue Thickness
This investigator-initiated randomized controlled clinical trial evaluated changes in peri-implant soft tissue thickness in the aesthetic zone following soft tissue augmentation.
- Conditions
- Dental Implants, Peri-Implant Tissues, Missing Tooth/Teeth
- Trial name
- NCT07324187
- Testing
- Connective Tissue Graft, Volume-Stable Collagen Matrix
- Where
- Poland
- Volunteers
- 36 people
- Sponsor
- Medical Innovation Center Wroclaw