Clinical trials: Soft Tissue Neoplasm
Uterine Leiomyoma
Evaluating Serum Sestrin in Leiomyoma Patients
Leiomyomas are the most common benign neoplasms of women's reproductive system affecting 20-30% of women within the reproductive ages.
- Trial name
- NCT04819633
- Testing
- Determination of serum sestrin levels
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Breast Cancer, Prostate Cancer
Eligibility Screening for the NIH Intramural Research Program Clinical Protocols
The purpose of this protocol is to provide patients with adequate informed consent to understand that screening tests with minimal health risk will be performed to evaluate their eligibility for a research study.
- Conditions
- Breast Cancer, Prostate Cancer, Lung Cancer, Sarcoma
- Trial name
- NCT00026754
- Where
- United States
- Volunteers
- 19,522 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Sarcoma, Endocrine Tumors
Comprehensive Omics Analysis of Pediatric and Adult Solid Tumors and Establishment of a Repository for Related Biological Studies
Background: Laboratory investigators who are studying common childhood cancers are interested in developing a tissue repository to collect and store blood, serum, tissue, urine, or tumors of children who have cancer or adults who…
- Conditions
- Sarcoma, Endocrine Tumors, Neuroblastoma, Retinoblastoma
- Trial name
- NCT01109394
- Where
- 5 sites in United States
- Volunteers
- 6,035 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Fibroid Uterus, Endometriosis
ICG to Assess Ovarian Perfusion
To assess the feasibility of using intravenous ICG to characterize the vascular perfusion of ovaries during gynecologic surgery
- Conditions
- Fibroid Uterus, Endometriosis, Uterus Myoma, Uterine Fibroid
- Trial name
- NCT03927651
- Testing
- ICG
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Uterine Leiomyoma
Trial of a Patient Education Tool For Leiomyoma
The goal of this study was to assess whether using a multimedia tool would enhance patient education and counseling on uterine leiomyomata.
- Trial name
- PETAL (NCT03847077)
- Testing
- iPad counseling, Standard Counseling
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Loyola University
Fibroids
Ulipristal vs. GnRHa Prior to Laparoscopic Myomectomy
Rationale: Laparoscopic myomectomy is increasingly performed over laparotomic myomectomy, because of the many benefits for the patient in terms of pain, hospital stay and recovery.
- Trial name
- MYOMEX (NCT02288130)
- Testing
- GnRHa, Ulipristal
- Where
- 9 sites in Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Dupuytren's Contracture
Safety and Efficacy of Two Concurrent Injections of AA4500 in Adult Subjects With Multiple Dupuytren's Contractures
The primary objective of this study is to assess the safety of two concurrent injections of AA4500 into the same hand in subjects with multiple Dupuytren's contractures with palpable cords followed 24 to 72 hours later by a…
- Trial name
- NCT01674634
- Testing
- XIAFLEX / XIAPEX
- Where
- 25 sites in United States
- Volunteers
- 715 people, healthy volunteers welcome
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Myopericytoma
MIYOPERİCYTOMA OF ORAL MUCOSE: CASE REPORT
Miyopericytoma (MPC) is defined as a benign tumor consisting mostly of oval-spindle-shaped myoid-appearing cells with perivascular growth.
- Trial name
- NCT05126420
- Testing
- biopsy
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Ankara University
Sarcoma
A First-in-Human Study of ¹⁷⁷Lu-HX02 in Sarcoma Patients
This is a single-center, open-label clinical study to evaluate the safety, biodistribution, and dosimetry of ¹⁷⁷Lu-HX02 injection in patients with sarcoma.
- Trial name
- NCT07847268
- Testing
- Safety, Biodistribution, and Dosimetry of ¹⁷⁷Lu-HX02 in Patients with Sarcoma
- Where
- China
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Uterine Leiomyomata (Fibroids)
Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PRA-027 Administered to Healthy Japanese Females
The primary purpose of this study is to assess the safety and tolerability of ascending single oral doses of PRA-027 in healthy Japanese females.
- Trial name
- NCT00444704
- Testing
- PRA-027
- Where
- Japan
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Gynecologic Disease, Gynecologic Cancer
Evaluation of Salivary RNA in Subjects Scheduled for Surgery for a Gynecologic Pathology
GynRAN is an international, multicentre, transversal, diagnostic and non-interventional study carried out in gynecology-obstetrics/gynecological oncology departments that aims to identify a diagnostic signature for gynecological…
- Conditions
- Gynecologic Disease, Gynecologic Cancer, Endometriosis, Ovarian Cancer
- Trial name
- GynRNA (NCT06392997)
- Testing
- Saliva sample
- Where
- 13 sites in France
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- ZIWIG
Soft Tissue and Bone Tumors, Sarcoma
Identification and Characterization of Molecular Markers in Musculoskeletal Tumors
The aim of the study is to improve the understanding of molecular mechanisms in the development and progression of musculoskeletal tumors. These tumors do have in general unfavorable prognosis and conventional treatments (e.g.
- Conditions
- Soft Tissue and Bone Tumors, Sarcoma, Sarcoma of Bone, Soft Tissue Sarcoma
- Trial name
- NCT02199938
- Testing
- Identification and characterization of molecular markers in musculoskeletal tumors
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Balgrist University Hospital
Adenomyosis of Uterus
Association of Ultrasound Features of the Myometrium Suggestive of Adenomyosis and Clinical Symptoms
The goal of this study/research is to assess the relationship between ultrasound features of the myometrium suggestive of adenomyosis and clinical symptoms of adenomyosis and to establish a reporting system for adenomyosis…
- Trial name
- MUSA3 (NCT07397715)
- Where
- 5 sites in Belgium, Poland and 2 more
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Swiss GO Trial Group
Adenomyosis, Leiomyoma
New Inflammation Markers for Distinguishing Uterine Adenomyosis and Leiomyoma
Both pelvic masses and preoperative diagnosis of them have still continued as an important investigation subject. It is important to discriminate the diagnoses of leiomyoma and adenomyosis before operation especially among…
- Conditions
- Adenomyosis, Leiomyoma, Inflammation
- Trial name
- NCT02997787
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kayseri Education and Research Hospital
Cervix Neoplasms, Endometrial Cancer
Comparison of the Effects of Fentanyl, Oxycodone, Butorphanol on Gastrointestinal Function
Postoperative ileus (POI) is a transient loss of coordinated peristalsis precipitated by surgery and exacerbated by opioid pain medication.So,how to provide patients with ideal analgesia without affecting the recovery of…
- Conditions
- Cervix Neoplasms, Endometrial Cancer, Adenomyosis, Fibroid Uterus
- Trial name
- NCT04295109
- Testing
- the drug of intravenous patient-controlled analgesia
- Where
- China
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Uterine Fibroid
Epidemiology and Risk Factors of Uterine Fibroids in China
Uterine fibroids are the most common form of benign uterine tumors in the uterine muscle layer, which had a certain rate of malignancy, but it is rare.
- Trial name
- NCT05840042
- Where
- China
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Wenwen Wang
Musculoskeletal Abnormality, Pediatric
Reliability and Acceptability of Real-time Virtual Video Pediatric Gait, Arms, Legs and Spine (V-pGALS)
The use of telemedicine in musculoskeletal assessment has been historically low. The current COVID 19 global pandemic has forced a paradigm shift with many centers rapidly adopting virtual visits to conduct care resulting in…
- Trial name
- NCT04668820
- Testing
- video Pediatric Gait, Arms, Legs and Spine (V-pGALS)
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Marmara University
Uterine Fibroids, Endometriosis
AMH Levels Change During Treatment With GnRh Agonist
To evaluate the variation of AMH levels in women undergoing treatment with GnRHa, and to assess whether this variation correlates with changes in the antral and pre-antral follicle ultrasonographic count (AFC).
- Conditions
- Uterine Fibroids, Endometriosis, Endometriosis of Uterus, Pelvic Pain
- Trial name
- NCT02086279
- Testing
- GnRH analogue
- Where
- Italy
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Endometriosis, Uterine Fibroids
A Phase 1 Clinical Study to Evaluate the Effects of SHR7280 on the Pharmacokinetics of Midazolam, S-warfarin, Omeprazole, Digoxin, and Rosuvastatin in Healthy Subjects
The purpose of this study is to evaluate the effects of SHR7280 on the pharmacokinetics of midazolam, S-warfarin, omeprazole, digoxin and rosuvastatin in healthy subjects.
- Conditions
- Endometriosis, Uterine Fibroids, Assisted Reproduction
- Trial name
- NCT06949124
- Testing
- SHR7280 Tablets
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Fibroids
Fibroids in Women of Reproductive Age and Women Pregnancy
Dydrogesterone Multivitamin Nature treatment of fibroids in women of reproductive age and women pregnancy to lost the size fibroids.
- Trial name
- Fibroids (NCT02620345)
- Testing
- Dydrogesterone M ( case 1 ), Dydrogesterone M ( case 2 )
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Trieu, Nguyen Thi, M.D.