Clinical trials: Soft Tissue Neoplasm
Uterine Fibroids, Menorrhagia, Endometriosis
Study Comparing Conventional vs. Robotic-assisted Laparoscopic Hysterectomy
The purpose of this study is to compare two ways of performing laparoscopic hysterectomy - robotic-assisted vs. conventional laparoscopy.
- Trial name
- NCT00485355
- Testing
- conventional laparoscopic hysterectomy, robotic assisted laparoscopic hysterectomy
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Leiomyoma
Effect of Hepatic Impairment on the Pharmacokinetics, Safety and Tolerability of BAY1002670 (Vilaprisan)
Evaluate the potential effect of hepatic impairment on the pharmacokinetics, safety and tolerability of BAY1002670 (vilaprisan)
- Trial name
- NCT03092999
- Testing
- Vilaprisan (BAY1002670)
- Where
- 2 sites in Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Bayer
Multiple Osteochondroma, Enchondromatosis
Survey on Multiple Osteochondromas and Enchondromatoses During the Transition From Paediatric Care to Adult Care
This prospective observational study aims to understand the transition experiences and unmet needs of patients living with multiple osteochondromas or enchondromatoses during the paediatric to adult care, in order to produce a…
- Trial name
- PJMOE (NCT07839637)
- Where
- Italy
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Breast Cancer, Prostate Cancer
Eligibility Screening for the NIH Intramural Research Program Clinical Protocols
The purpose of this protocol is to provide patients with adequate informed consent to understand that screening tests with minimal health risk will be performed to evaluate their eligibility for a research study.
- Conditions
- Breast Cancer, Prostate Cancer, Lung Cancer, Sarcoma
- Trial name
- NCT00026754
- Where
- United States
- Volunteers
- 19,522 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Gynaecological Disease, Vitamin D Deficiency
Association Between Vitamin D and the Risk of Uterine Fibroids
The aim of this randomised clinical trial study is to evaluate whether supplementation with vitamin D could reduce the risk of uterine fibroids in reproductive stage women.
- Conditions
- Gynaecological Disease, Vitamin D Deficiency, Uterine Fibroids
- Trial name
- ABVDATROUF (NCT03586947)
- Testing
- Vitamin D3 400 UNT Oral Capsule
- Where
- China
- Volunteers
- 1,160 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Gastrointestinal Stromal Tumors, Metastasis
Salvage Surgery for Patients With Metastatic GIST With Rego
Some researches have shown surgery may acquire progression-free (PFS) benefit for selected patients with metastatic gastrointestinal stromal tumor (GIST) who received first-line imatinib and second-line sunitinib.
- Conditions
- Gastrointestinal Stromal Tumors, Metastasis, Disease Progression
- Trial name
- NCT04343456
- Testing
- Salvage surgery with massive debulking
- Where
- Taiwan
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Hemorrhage/Blood Loss During Myomectomies, Fibroids
Use of Intravenous Tranexamic Acid During Myomectomy
The purpose of this study is to determine the effect of the early administration of intravenous (IV) Tranexamic acid (TA) on perioperative bleeding (as defined by measured intraoperative estimated blood loss (EBL), change in pre…
- Trial name
- TA (NCT02620748)
- Testing
- Tranexamic Acid, Saline Solution
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- George Washington University
Uterine Fibroids, Abnormal Uterine Bleeding
Does 3D Laparoscopy Improve Vaginal Cuff Suture Time?
The objective aim is to evaluate whether the use of 3D laparoscopy facilitates the vaginal cuff closure of the vaginal cuff during a total laparoscopic hysterectomy among novice laparoscopists (PGY 2-4, Fellow).
- Conditions
- Uterine Fibroids, Abnormal Uterine Bleeding, Pelvic Pain, Adenomyosis
- Trial name
- 3DRCT (NCT02192606)
- Testing
- Storz 3D Laparoscopy System, 2D Laparoscopy
- Where
- 2 sites in United States, Denmark
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Breast Carcinoma, Malignant Digestive System Neoplasm
Studying the Workflow of the American College of Surgeons Geriatric Surgery Program to Improve Clinical Outcomes in Older Adults Undergoing Surgery at the James Cancer Hospital
This study examines how the American College of Surgeons Geriatric Surgery Verification Program, also called the ACS GSV Program, is implemented at the James Cancer Hospital.
- Conditions
- Breast Carcinoma, Malignant Digestive System Neoplasm, Malignant Female Reproductive System Neoplasm, Malignant Genitourinary System Neoplasm
- Trial name
- NCT07606287
- Testing
- Serious Illness Conversation Program training, ACS Geriatric Surgery Verification Program Implementation
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Minor Intra-uterine Abnormalities
The Impact of Treating Minor Uterine Cavity Abnormalities Diagnosed by Office Hysteroscopy in Unselected In Vitro Fertilization (IVF) Cases
This is a comparative, controlled trial to evaluate the impact of treating undetected, asymptomatic, predefined minor uterine cavity abnormalities on the success of IVF treatment.
- Trial name
- NCT00830401
- Testing
- Treatment of predefined abnormality by hysteroscopic surgery, Ofloxacinum/Doxycycline
- Where
- Netherlands
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Head and Neck Cancer
Safety Study of Musculoskeletal Ultrasonographic to Assess Disabilities Arm of Head and Neck Cancer Patient
The investigators suppose: 1. SND may cause damage to the soft tissue around shoulder girdle. 2. The soft tissue injury may be related with the order of severity of wing scapula and duration after SND.
- Trial name
- NCT02369276
- Testing
- ultrasonography and elastography
- Where
- Taiwan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Appendicitis, Evidence of Cholecystectomy
Point of Care 3D Ultrasound for Various Applications: A Pilot Study
Summary 1. Purpose and Objective: The purpose of this study is to test the feasibility of rapid acquisition of point of care 3D ultrasound in obtaining abdominal and/or pelvic images.
- Conditions
- Appendicitis, Evidence of Cholecystectomy, Gallstones, Pregnancy, Ectopic
- Trial name
- NCT02831556
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Duke University
Photodamaged Skin
Study Comparing Two Serums With Intense Pulsed Light for the Treatment of Moderate to Severe Photodamage and Crepiness on the Forearms
The primary objective is to compare Re-Q Pro-Longevity serum versus vehicle serum combined with Intense Pulsed Laser for the treatment of moderate to severe photodamage and crepiness on the dorsal forearms.
- Trial name
- NCT07686198
- Testing
- Right Arm treated with Active Re-Q Pro-Longevity Serum and Intense Pulsed Light Therapy, Left Arm treated with vehicle serum and Intense Pulsed Light Therapy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Soft Tissue Sarcoma, Non Metastatic Disease
A Scandinavian Sarcoma Group Protocol for Patients With High-risk Soft Tissue Sarcoma of the Extremities and Trunk Wall
SSG XX is a phase II trial for high-risk soft tissue sarcomas (STS) of the extremities and trunk wall. Prognostic factors (histopathological markers) are used to identify high-risk tumors.
- Trial name
- SSGXX (NCT00790244)
- Testing
- doxorubicin , ifosfamide, doxorubicin, ifosfamide
- Where
- 2 sites in Sweden
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Dupuytren Contracture
BOND Study: the Benefit Of Night Splinting in Dupuytrens'
The BOND study is a prospective, randomised single blinded controlled trial to assess the effect of night splinting in patients who have had collagenase injection and manipulation therapy for Dupuytren's Contracture.
- Trial name
- BOND (NCT03031080)
- Testing
- Thermoplastic Hand Splint
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Osteosarcoma
Extracorporeal Shock Wave Therapy on Osteoblast-Like Cells In- Vitro Study
The idea of treating different deformities or diseases in the maxillofacial region with Extracorporeal Shockwave Therapy (ESWT) has recently become popular.
- Trial name
- ESWT (NCT05801887)
- Testing
- Extracorporeal shockwave device, No ESWT
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Uterine Fibroids
Uterine Leiomyoma Treatment With Radiofrequency Ablation (ULTRA) Registry
The ULTRA Registry is a nationwide observational arm of the ULTRA trial. Data from the ULTRA Registry will be used to evaluate the long-term safety and efficacy of laparoscopic RF ablation (Acessa).
- Trial name
- ULTRA Registry (NCT02100904)
- Testing
- Radiofrequency ablation of fibroids, Myomectomy of fibroids
- Where
- 12 sites in United States
- Volunteers
- 578 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Uterine Fibroid
Use of v Care in Abdominal Hysterectomy
The investigators use v care during abdominal hysterectomy and evaluate its effect on duration of operation time, surgical complications and vaginal length.
- Trial name
- NCT02371811
- Testing
- uterine manipulator (v care)
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Osteosarcoma
Therapy Trial to Determine the Safety and Efficacy of Heavy Ion Radiotherapy in Patients With Osteosarcoma
The primary objectives of this trial are the determination of feasibility and toxicity of Heavy Ion Radiotherapy (C12) in patients with non-resectable osteosarcoma.
- Trial name
- NCT01005043
- Testing
- heavy ion radiotherapy (C12)
- Where
- Germany
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University Hospital Heidelberg
Endocrine Disease, Infertility
Evaluation of Women With Endocrine and Reproductive-Related Conditions
This study was designed to allow inpatient and outpatient evaluation of women with a variety of reproductive and endocrine-related disorders for purposes of research and physician education.
- Conditions
- Endocrine Disease, Infertility, Leiomyoma, Endometriosis
- Trial name
- NCT00001850
- Where
- United States
- Volunteers
- 833 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)