Clinical trials: Soft Tissue Reconstruction
Soft Tissue Defect of the Finger
A Comparison of Dorsal Branch of the Digital Nerve Versus Dorsal Digital Nerve for Finger Pulp Reconstruction
As the donor nerve attached with the flap, the dorsal branch of the digital nerve and the dorsal digital nerve is commonly used for finger pulp reconstruction.This study compares two donor nerves: the dorsal branch of the digital…
- Trial name
- NCT01826539
- Testing
- flap includes a donor nerve
- Where
- China
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Tangshan
Sensory Reconstruction of the Volar Aspect of the Finger, The Heterodigital Neurocutaneous Island Flap
Repair of Soft Tissue Defect of the Finger Using the Heterodigital Neurocutaneous Island Flap
The dorsum of the finger is a reliable flap donor site in reconstructive hand surgery because of its similar quality to the original.
- Trial name
- NCT01778296
- Testing
- the neurocutaneous island flap
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Tangshan
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Tendon-Bone Versus All-Soft-Tissue for ACL Reconstruction: A Patient-Blinded Randomized Clinical Trial
In primary pediatric Anterior cruciate ligament (ACL) reconstruction, the quadriceps tendon with either tendon and patellar bone or an all-tendon graft is commonly employed.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- NCT04039971
- Testing
- ACL Reconstruction
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Colorado, Denver
Full-thickness Skin Defects, Degloving Injuries
RECELL® System Combined With Meshed Autograft for Reduction of Donor Skin Harvesting in Soft Tissue Reconstruction
A prospective randomized within-subject controlled study to compare the clinical performance of conventional autografting with and without the RECELL system on acute non-burn full-thickness skin defects.
- Conditions
- Full-thickness Skin Defects, Degloving Injuries, Crush Injuries, Laceration of Skin
- Trial name
- NCT04091672
- Testing
- Control Intervention (Conventional Autograft), Investigational Intervention (RECELL + more widely meshed autograft)
- Where
- 18 sites in United States
- Volunteers
- 65 people
- Sponsor
- Avita Medical
Wounds and Injuries, Wound Infection
Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wounds and Injuries, Wound Infection, Facial Bones Fracture, Soft Tissue Injuries
- Trial name
- FTFDT2 (NCT03880188)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Osteosarcoma, Ewing Sarcoma
Adherence to a Personalized Home Exercise Program in Patients With Bone Tumor Undergoing Lower Extremity Salvage Surgery
The objective of this study is to describe adherence to a personalised home exercise program in patients undergoing resection and reconstruction of lower limb for bone tumor and neoadjuvant chemotherapy treatment in the first six…
- Conditions
- Osteosarcoma, Ewing Sarcoma, Chondrosarcoma, Bone Tumor
- Trial name
- ADER (NCT05779670)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Istituto Ortopedico Rizzoli
Lateral Ankle Instability
Retrospective Study of Suture Tape for Soft Tissue Reconstruction in Patients Suffering From Lateral Ankle Instability
This study is intended to be a retrospective chart review of patients with chronic ankle instability who have undergone a lateral ligament reconstructive procedure for ATFL repair (isolated or non-isolated) with suture tape…
- Trial name
- NCT06829667
- Testing
- Arthrex InternalBrace
- Where
- 4 sites in United States
- Volunteers
- 103 people
- Sponsor
- Stryker Trauma and Extremities
Nerve Injury, Digital Pulp Defect
Free Dorsal Digital Flap for Reconstruction of Volar Soft Tissue Defect of Digits
The aim of the current report is to investigate the feasibility of transferring the free dorsal digital flap, including both dorsal branches of the proper digital nerves (PDNs), to reconstruct the volar soft tissue defect of…
- Trial name
- NCT01533337
- Testing
- Free dorsal digital flap
- Volunteers
- 12 people
- Sponsor
- The Second Hospital of Tangshan
Fibrosis Breast
Shockwave in Postoperative Breast Reconstruction Fibrosis
This study evaluates the potential for extracorporeal shockwave therapy to reduce post-operative soft tissue fibrosis.
- Trial name
- NCT06919042
- Testing
- Pulsed Acoustic Cellular Expression therapy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Northwestern University
Wound; Head, Multiple, Wound; Head, Scalp
Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wound; Head, Multiple, Wound; Head, Scalp, Wound; Head, Wound Infection
- Trial name
- FTFDT3 (NCT03872544)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Ankle Injuries
Sural Flap and Anterolateral Thigh Flap in Tissue Reconstruction Around the Ankle
The aim of the study is to evaluate the outcomes of coverage of soft tissue defects of leg and foot by modified sural flap versus anterolateral thigh flap
- Trial name
- NCT04906967
- Testing
- flaps
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sohag University
Ulnar Collateral Ligament Sprain, Tibialis Posterior Dysfunction
Validating the Speckle Tracking Methods on Soft Tissue Strain, Displacement, and Roles in Physical Therapy
This three-year research project aims to test the hypothesis that strain and displacement characteristics of human soft tissues are influenced by (1) habitual physical activity, (2) functional impairment, and (3) training…
- Conditions
- Ulnar Collateral Ligament Sprain, Tibialis Posterior Dysfunction, Anterior Cruciate Ligament Reconstruction Rehabilitation, Ultrasound Evaluation
- Trial name
- NCT07485530
- Testing
- blood flow restriction training, nordic exercise training
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Hamstring Muscle Strain, Adult Acquired Flatfoot Deformity
Correlation Between Soft Tissue Displacement and Functional Performance in Orthopedic Patients
The goal of this clinical trial is to investigate the correlations between dynamic soft tissue displacement, mechanical properties, and functional recovery across three studies: biceps femoris long head (BFlh) muscle injury…
- Conditions
- Hamstring Muscle Strain, Adult Acquired Flatfoot Deformity, Ulnar Collateral Ligament Sprain After Reconstruction
- Trial name
- NCT07870408
- Testing
- Nordic Hamstring Exercise Training, Custom Foot Orthoses and Exercise Therapy, Forearm Blood Flow Restriction Training
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Taiwan University Hospital
Reconstruction of Head Soft Tissue Defects, Reconstruction of Neck Soft Tissue Defects
Reliability and Versatility of Supraclavicular Artery Flap in Reconstruction of Head and Neck Soft Tissue Defects
This is a case series study conducted at plastic surgery department Sohag University including 20 patients The aim of this thesis is to evaluate reliability and versatility of Supraclavicular artery flap in the reconstruction of…
- Trial name
- NCT05727150
- Testing
- Reconstruction of Soft tissue defects of head and neck by Supraclavicular artery flap
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Bankart Lesions, SLAP Lesion
PMCF Study on the Safety, Performance and Clinical Benefits Data of the ToggleLoc™ 2.9mm and JuggerLoc™ in the Shoulder
The study is a multicenter, retrospective, non-randomized, non-controlled and consecutive series post-market study. The purpose of this study is to collect data confirming safety, performance and clinical benefits of the…
- Conditions
- Bankart Lesions, SLAP Lesion, Acromioclavicular; Dislocation, Capsular Shift/Capsulolabral Reconstruction
- Trial name
- NCT05584553
- Testing
- ToggleLoc 2.9 mm soft tissue device, JuggerLoc soft tissue device
- Where
- 3 sites in United States, Spain
- Volunteers
- 214 people
- Sponsor
- Zimmer Biomet
Osteosarcoma
Donor Site Morbidity After Free Vascularized Fibular Graft
This study was carried out at Assiut University to Asses the long-term donor site morbidity following free vascularized fibular transfer because there is a limited information regarding the long-term donor morbidity of this type…
- Trial name
- NCT06324916
- Testing
- Xray
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assiut University
Soft Tissue Support and Repair
The SeriScaffold® Use in Reconstruction Post Market Study for Tissue Support and Repair in Breast Reconstruction Surgery in Europe
This is a post-market study of the use of SeriScaffold® for soft tissue support and repair in breast reconstruction surgery.
- Trial name
- NCT01389232
- Testing
- SeriScaffold® Surgical Scaffold
- Where
- 5 sites in Germany, Italy and 2 more
- Volunteers
- 104 people
- Sponsor
- Sofregen Medical, Inc.
Post Traumatic Soft Tissue Defects That Could be Reached by Pedicled Anterolateral Thigh Flap, Post Tumor Excision Soft Tissue Defects
Reliability and Versatility of Pedicled Anterolateral Thigh Flap in Reconstruction of Soft Tissue Defects
a prospective case series study for evaluation of the reliability and versatility of pedicled anterolateral thigh flap in the reconstruction of soft tissue defects as regards flap survival and complications, donor site morbidity…
- Conditions
- Post Traumatic Soft Tissue Defects That Could be Reached by Pedicled Anterolateral Thigh Flap, Post Tumor Excision Soft Tissue Defects, Post Debridement Soft Tissue Defects
- Trial name
- NCT06841419
- Testing
- surgical reconstruction of a soft tissue defects by a pedicled flap
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
ACL Reconstruction
Effects of Blood Flow Restriction Training and Instrument-Assisted Soft Tissue Mobilization for Pain, Strength, Range of Motion, and Kinesiophobia Among ACL Reconstruction Patients.
This randomized clinical trial aims to compare the effects of Blood Flow Restriction Training (BFR) and Instrument-Assisted Soft Tissue Mobilization (IASTM) on pain, quadriceps muscle strength, knee range of motion (ROM), and…
- Trial name
- NCT07662850
- Testing
- Blood Flow Restriction Training, Instrument-Assisted Soft Tissue Mobilization (IASTM)
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Breast Reconstruction
Melodi Matrix™ in Breast Reconstruction
Prospective, multicenter, randomized, controlled trial evaluating the safety and effectiveness of an absorbable antibacterial matrix device in two stage prepectoral alloplastic breast reconstruction.
- Trial name
- NCT06027996
- Testing
- Absorbable Antibacterial Matrix
- Where
- 10 sites in United States
- Volunteers
- 702 people
- Sponsor
- Melodi Health, Inc.