Clinical trials: Soilings, Fecal
Chronic Constipation With Overflow, Encopresis With Constipation and Overflow Incontinence
Sacral Neuromodulation in Children and Adolescents
The purpose of this study is to assess the efficacy of neuromodulation for treatment of chronic constipation and fecal incontinence in pediatric patients and to evaluate the differences between the invasive vs.
- Conditions
- Chronic Constipation With Overflow, Encopresis With Constipation and Overflow Incontinence, Hirschsprung's Disease, Anorectal Malformations
- Trial name
- NCT04713085
- Testing
- Invasive Sacral Neuromodulation, Non-invasive Sacral Neuromodulation
- Where
- Germany
- Volunteers
- 48 people
- Sponsor
- Friedrich-Alexander-Universität Erlangen-Nürnberg
Anal Incontinence
Anal Incontinence and Its Impact on Quality of Life and Physical Activity Among Hungarian Women and the Hungarian Language Validation of the International Consultation on Incontinence Modular Questionnaire-Bowels (ICIQ-B)
The aim of the study is to assess the prevalence of anal incontinence among Hungarian women who have given birth at least once before, and to examine the impact of anal incontinence on the quality of life and physical activity of…
- Trial name
- NCT06423222
- Where
- Hungary
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Urinary Incontinence, Anal Incontinence
Pelvic Floor Muscle Training During Pregnancy
The project seeks to investigate effectiveness of PFMT during pregnancy.
- Conditions
- Urinary Incontinence, Anal Incontinence, Pelvic Organ Prolapse, Sexual Dysfunction
- Trial name
- NCT07104292
- Testing
- PFMT, Standard care
- Where
- Denmark
- Volunteers
- 804 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Anal Incontinence, Fecal Incontinence
Treatment of Anal Incontinence With Intersphincteric Implants
The purpose of this study is to determine whether treatment with intersphincteric implants is an effective and safe treatment option for patients with anal incontinence
- Trial name
- NCT03080753
- Testing
- Sphinkeeper
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Region Skane
Pelvic Floor Dysfunction, Perineal Laceration
Perineal Protection Device for Reducing Perineal Trauma During Vaginal Delivery in First-time Mothers: a Multicenter Randomized Controlled Trial
The goal of this clinical trial is to determine whether using a soft perineal protection device (BabySlide®) in addition to standard manual perineal support during vaginal delivery can reduce the risk of perineal trauma in…
- Conditions
- Pelvic Floor Dysfunction, Perineal Laceration, Wound Dehiscence, Anal Incontinence
- Trial name
- PeriPROTECT (NCT07862660)
- Testing
- Perineal protection device, BabySlide, Standard manual perineal support
- Where
- Sweden
- Volunteers
- 4,226 people
- Sponsor
- Region Skane
Perianal Fistula, Fistula-in-Ano
Open Fistulectomy vs. Laser Closure for Low Perianal Fistula
Perianal fistula is an abnormal tunnel connecting the anal canal to the perianal skin, frequently causing chronic pain, discharge, and impaired quality of life.
- Conditions
- Perianal Fistula, Fistula-in-Ano, Low Perianal Fistula
- Trial name
- NCT07797842
- Testing
- Fistula-tract Laser Closure (FiLaC), Open Fistulectomy
- Volunteers
- 40 people
- Sponsor
- Assiut University
Encopresis
Internet-based Treatment of Early Childhood Fecal Incontinence
Encopresis, also known as fecal incontinence, is the voluntary or involuntary passage of stools causing soiling of clothes by a child over 4 years of age.
- Trial name
- NCT00067769
- Testing
- Internet-based intervention UCanPoopToo, treatment as usual
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Rectum Cancer, Faecal Incontinence
Exploring the Effect of Colonic J-pouch in Anorectal Preservation Surgery for Ultra-low Rectal Cancer.
The occurrence of colorectal cancer has increased from the third most common cancer in 2018 to the second most common cancer in 2023.
- Conditions
- Rectum Cancer, Faecal Incontinence, Faecal Incontinence with Faecal Urgency, Low Anterior Resection Syndrome
- Trial name
- NCT06601985
- Testing
- J-pouch anastomosis, direct anastomosis
- Where
- China
- Volunteers
- 154 people
- Sponsor
- Shanghai 10th People's Hospital
Faecal Incontinence
A Study to Evaluate Topical Phenylephrine Gel in the Management of Faecal Incontinence
The aim of the study is to test the hypothesis that topical application of phenylephrine improves faecal continence and quality of life in subjects with passive faecal incontinence after ileo-anal pouch construction.
- Trial name
- NCT00420797
- Testing
- 10% Phenylephrine hydrochloride gel
- Where
- United Kingdom
- Sponsor
- S.L.A. Pharma AG
Faecal Incontinence, Bowel Incontinence
UK Trial of Percutaneous Tibial Nerve Stimulation in Patients With Faecal Incontinence
Faecal incontinence occurs when a person passes faeces (stools) without the usual control. It is a distressing condition that is actually very common although under-reported because of embarrassment.
- Trial name
- CONFIDeNT (NCT02349334)
- Testing
- Percutaneous Tibial Nerve Stimulation
- Volunteers
- 227 people
- Sponsor
- Queen Mary University of London
Multiple Sclerosis, Disabilities Multiple
The Relationship of Neuropathic Pain With Incontinence, Disability and Life Quality in Multiple Sclerosis Patients
The aim of this study to evaluate the relationship of neuropathic pain with urinary and bowel incontinence, functional disability and quality of life in patients with multiple sclerosis.
- Conditions
- Multiple Sclerosis, Disabilities Multiple, Quality of Life, Incontinence, Urinary
- Trial name
- NCT05374811
- Testing
- Neuropathic Pain
- Where
- Turkey (Türkiye)
- Volunteers
- 175 people
- Sponsor
- Istanbul University - Cerrahpasa
Faecal Incontinence
Evaluation of the Fast Fill Technique for Anal Acoustic Reflectometry (AAR) in the Incontinent Anal Sphincter
Anal Acoustic Reflectometry (AAR) is a technique that has been studied in our department over the last 6 years. Sound waves pass into a balloon placed in the anal canal and are used to measure the cross-sectional area.
- Trial name
- NCT02782364
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- Manchester University NHS Foundation Trust
Rectal Cancer
Italian Validation of the LARS Score
BACKGROUND and RATIONALE Colorectal cancer, with 49,000 new diagnoses expected in 2019 (27,000 in men and 22,000 in women) represents, in Italy, the third neoplasm in men (14%) and the second in women (12%).
- Trial name
- NCT04406311
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Parturition
Perineal Echography in the Delivery Room for the Detection of Anal Lesions
The main objective of this study is to compare the rate of anal incontinence (measured by the Wexner score, qualitative and quantitative (> 4)) at 3 months post partum among primiparas with vaginal tears ≥ 2nd degree who receive…
- Trial name
- OASIS 1 (NCT01320995)
- Testing
- Perineal ultrasound
- Where
- 2 sites in France
- Volunteers
- 111 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Low Anterior Resection Syndrome
Paula Method of Exercises in Patients With LARS Syndrome
Sphincter sparing rectal resection surgery, either total mesorectal excision (TME) with a temporary loop ileostomy or partial mesorectal excision (PME), is the mainstay of rectal cancer treatment , however, these treatments are…
- Trial name
- NCT05016583
- Testing
- Paula Method
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Hadassah Medical Organization
Fecal Incontinence
Effect of Anorectal Biofeedback on Encopresis in School Aged Girls After Sexual Assault
Females who have been sexually abused anally, have a disturbed anorectal motility. They have an increased resting pressure at the lower part of the anal canal.
- Trial name
- NCT04652024
- Testing
- Anorectal manometry
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Badr University
Faecal Incontinence
SphinkeeperTM Procedure for Treating Severe Faecal Incontinence
Patients, aged 18 - 90 years, undergoing sphinkeeper operation at the Department of General Surgery at the Medical University of Vienna are enrolled into our study.
- Trial name
- NCT04664868
- Testing
- Sphinkeeper™
- Where
- Austria
- Volunteers
- 11 people
- Sponsor
- Medical University of Vienna
Chronic Constipation With Overflow, Encopresis With Constipation and Overflow Incontinence
Non-invasive Sacral Nerve Stimulation in Children and Adolescents With Chronic Constipation
The purpose of this study is to assess the efficacy of additional neuromodulation for treatment of chronic constipation in pediatric patients
- Conditions
- Chronic Constipation With Overflow, Encopresis With Constipation and Overflow Incontinence, Hirschprung's Disease, Anorectal Malformations
- Trial name
- NCT04710433
- Testing
- Non-invasive Neuromodulation, Medical and Behavioral Therapy
- Where
- Germany
- Volunteers
- 59 people
- Sponsor
- Friedrich-Alexander-Universität Erlangen-Nürnberg
Faecal Incontinence, Asymptomatic Condition
Anal Canal Functional Assessment Using EndoFLIP
Faecal incontinence (FI) is characterized by involuntary loss of rectal content through the anal canal. FI is psychologically and socially debilitating problem that can dramatically affect patient's quality of life, often in…
- Trial name
- NCT04741893
- Testing
- EndoFLIP
- Where
- Hong Kong
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Faecal Incontinence, Pelvic Floor Disorders
Optimising Treatments for Faecal Incontinence
The purpose of the study is to directly compare two medical treatments for faecal incontinence: Renew™ Anal Insert and Percutaneous Tibial Nerve Stimulation (PTNS) for a period of 12 weeks. Both are routinely used in our practice.
- Trial name
- NCT04273009
- Testing
- Renew VS PTNS
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- London North West Healthcare NHS Trust