Clinical trials: Solar Elastosis
Skin Texture Disorder, Photoaging
Safety and Efficacy Evaluation of the Mosaic Ultra Device
Evaluate the Safety and Efficacy of the Mosaic Ultra 1550nm system for the treatment of skin tone and texture, facial rejuvenation, photoaging, wrinkles, scars, stretch marks, acne vulgaris and hair loss.
- Conditions
- Skin Texture Disorder, Photoaging, Wrinkle, Scar
- Trial name
- NCT06117293
- Testing
- Mosaic
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- CynosureLutronic
Solar Elastosis
Histologic Response to UVA and UVB Exposure During the Use of Sunscreen
Anti-inflammatory and anti-oxidant agents have become the important ingredients in sunscreen. However, there is no histologic study about the effects of anti-inflammatory and anti-oxidative properties of sunscreen to prevent…
- Trial name
- NCT01892150
- Testing
- Sunscreen
- Where
- Thailand
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Healthy Volunteers
The Effect of Arabica Gayo Cascara Pulp Extract on Photoaging
The purpose of this study was to assess the safety of Gayo Arabica coffee pulp extract cream as an antioxidant for the skin that can increase skin moisture
- Trial name
- NCT05390489
- Testing
- Cascara pulp arabica gayo coffee cream
- Where
- Indonesia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wahyu Lestari
Smoking
Smokerface Mirroring in Brazil RCT
Before February 2018 the baseline survey is conducted in about 60 class in Brazilian secondary schools. These classes are randomized to control and intervention group in a 1/1 manner.
- Trial name
- NCT03178227
- Testing
- Photoaging Mirroring Intervention
- Where
- 2 sites in Brazil, Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Giessen
Photoaging, Wrinkle
Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With Fractional Ablative CO2 Laser for Facial Rejuvenation
This randomized, single-center, double-blinded, split-face, controlled clinical trial was conducted to investigate the tolerability, safety, and efficacy of a post-procedure cream when used immediately after fractional ablative…
- Conditions
- Photoaging, Wrinkle, Skin Laxity
- Trial name
- NCT06366503
- Testing
- Fractional Ablative CO2 Laser, Facial Cleanser, Facial Moisturizer
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Fine Lines, Wrinkle
A Clinical Study to Evaluate the Efficacy of an Anti-Aging Serum
This double-blind, randomized, controlled, single-center clinical trial was conducted to assess the efficacy and tolerance of an anti-aging serum to improve moderate overall photodamage and skin fatigue of aging skin after 7 days…
- Conditions
- Fine Lines, Wrinkle, Photoaging
- Trial name
- NCT05271136
- Testing
- Anti-aging Serum, Facial Moisturizer, Cleansing Lotion
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Photoaging
Photoaging Treatment With Imiquimod
Recently it was demonstrated that imiquimod in addition to exerting a repairing effect in pre malignant and malignant lesions caused by UV radiation it reverses histopathological changes associated with the photoaging skin.
- Trial name
- NCT01935310
- Testing
- Imiquimod
- Where
- Colombia
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- CES University
Other Skin Changes Due to Chronic Exposure to Nonionizing Radiation
SUV PDL1/PD1 in Sun Damaged & Sun Protected Human Skin of Participants
The purpose of this research study is to look at how the proteins and genes in people's skin change when they're exposed to simulated sunlight.
- Trial name
- NCT06177106
- Testing
- Solar Simulated Light
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Tobacco Use Cessation, Smoking Cessation
Evaluating the Impact of a Photoaging App Versus School-Based Educational Intervention on Adolescents' Knowledge, and Attitudes Towards Tobacco Use
Tobacco use is a leading cause of preventable morbidity and mortality worldwide. It has been estimated that by 2030, tobacco use will cause approximately 10 million deaths per year worldwide, with 70% of those occurring in low…
- Conditions
- Tobacco Use Cessation, Smoking Cessation, Smoking Prevention
- Trial name
- NCT06483763
- Testing
- SmokerFace App from the Education Against Tobacco (EAT) program, The use of standardized school-based educational module
- Where
- Oman
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- Sultan Qaboos University
Rhytidosis Facialis
A Study Evaluating Blended Belotero for the Treatment of Etched-in Fine Facial Lines
This is a single center study for adult females or males ages 25 to 75 years who are seeking treatment for etched-in fine lines of the cutaneous lip, and/or radial cheek area, and/or nasolabial folds, and/or melolabial folds…
- Trial name
- NCT02626598
- Testing
- Blended Belotero
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Skin Care and Laser Physicians of Beverly Hills
Erythema, Sun Damaged Skin
Efficacy Study of a Novel Skin Health Product to Reduce an UVB Induced Erythema
The aim of this study is to determine the erythema-reducing efficacy of a test product in two concentrations on a light sunburn induced by a sun simulator compared to an untreated control and a placebo product.
- Conditions
- Erythema, Sun Damaged Skin, Skin Inflammation
- Trial name
- NCT05300542
- Testing
- Topical Cream with 0.5% Active, Topical Cream with 1% Active
- Where
- Germany
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Photoaging
Evaluation of Hexyresorcinol vs Hydroquinone for Photoaging
Photoaging is a common concern within the cosmeceutical industry with many products that are available. One frequently used product is hydroquinone that is used to even skin tone. However, hydroquinone has several shortcomings.
- Trial name
- NCT04345094
- Testing
- Hexylresourcinol, Hydroquinone
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sytheon Ltd.
Photoaging
Combination Versus Laser Treatment Only
Our objective is to determine the effects of (1) basic skin care regimen + "active" (Lytera 2.0) vs. (2) basic skin care regimen only, both groups combined with laser, on the appearance of skin tone and photo-aging on the face.
- Trial name
- NCT03661697
- Testing
- Laser Therapy, Basic Skin Care Regimen, Lytera
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Miami
Cutaneous Photoaging
Efficacy and Safety of Kinetin 0.1% for Treatment of Skin Photoaging
The purpose of the study is to evaluate the change in the severity and clinical signs of skin photoaging among Filipino patients using Kinerase cream (Kinetin 0.1%).
- Trial name
- NCT01898182
- Testing
- Kinetin, N6-furfuryladenine, 0.1%
- Where
- 2 sites in Philippines
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Makati Medical Center
Intrinsic Aging of Skin, Skin Wrinkling
Study of Intradermal Injections of RCS-01 in Male and Female Subjects
The primary purpose of this study is to assess the safety profile of RCS-01 injections as compared to placebo injections. This study will also measure the impact these injections will have on skin markers related to aging through…
- Conditions
- Intrinsic Aging of Skin, Skin Wrinkling, Solar Degeneration of Skin
- Trial name
- NCT02391935
- Testing
- RCS-01
- Where
- Germany
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- RepliCel Life Sciences, Inc.
Photoaging
Effectivity of 1 Finger Tip Unit Compared to 2 Finger Tip Units 0.05% Tretinoin Cream
This clinical study will compare the efficacy of using one fingertip unit and two fingertip units of 0.05% before and after 30% trichloroacetic acid chemical peel procedure for facial skin rejuvenation in 35-60 years old female…
- Trial name
- NCT05004909
- Testing
- 0.05% Tretinoin
- Where
- Indonesia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Dr.dr.Irma Bernadette, SpKK (K)
Photoaging
Oral Supplementation of Astaxanthin on Skin Photoaging, Hydration and Elasticity
This study is a double-blind placebo controlled study to assess whether oral astaxanthin can improve skin hydration, skin elasticity, improve skin pigmentation, and reduce facial redness.
- Trial name
- NCT05882084
- Testing
- Astaxanthin 6 mg daily
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Skin Ageing
Effect of Pomanox® on Skin Ageing (POMASKIN)
The state of skin health impacts not only on the general health of individuals, but also on mental health. Ultraviolet radiation (UV) is one of the main external factors that causes skin ageing, producing photo-aging…
- Trial name
- POMASKIN (NCT05842447)
- Testing
- 367 mg Pomanox group, 700 mg Pomanox group, Control group
- Where
- 2 sites in Spain
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Fundació Eurecat
Photodamaged Skin, Photoaging
Altreno for Chest Rejuvenation
This is a single-center, prospective, double-blind, randomized, vehicle-controlled study to evaluate the efficacy, safety and patient satisfaction of tretinoin 0.05% lotion (Altreno) for chest rejuvenation.
- Trial name
- NCT04096742
- Testing
- tretinoin 0.05% lotion (Altreno), Vehicle
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Photoaging of Skin, Skin Aging
The Role of Red Flavonoid in Photoaging
The goal of this clinical trial is to learn about the effects of "red flavonoid" substance on skin, which is extracted from a plant called Camellia japonica, in adults aged of 45 or older with photo-damaged skin.
- Trial name
- NCT05854628
- Testing
- skin biopsy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University