Clinical trials: Solid Malignancy
Malignant Solid Neoplasm, Hematopoietic Neoplasms
Optimizing Health Related Quality of Life Measurement in Adolescent and Young Adult Oncology
This study evaluates how adolescent and young adults with cancer in the U.S. and their loved ones respond to questions that will later be used with people who may have cancer and other chronic health conditions
- Conditions
- Malignant Solid Neoplasm, Hematopoietic Neoplasms, Lymphatic System Neoplasm
- Trial name
- NCT06897137
- Testing
- Surveys/Questionnaires
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Small Cell Lung Cancer, Solid Tumors
A Study of AL8326 in Healthy Subjects
This experiment plans to enroll 6-8 healthy male subjects in China, and ultimately collect complete test samples and data from at least 6 subjects as the standard.
- Trial name
- NCT07132957
- Testing
- 14C-labeled AL8326
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Advenchen Laboratories Nanjing Ltd.
Sarcoma, Endocrine Tumors
Comprehensive Omics Analysis of Pediatric and Adult Solid Tumors and Establishment of a Repository for Related Biological Studies
Background: Laboratory investigators who are studying common childhood cancers are interested in developing a tissue repository to collect and store blood, serum, tissue, urine, or tumors of children who have cancer or adults who…
- Conditions
- Sarcoma, Endocrine Tumors, Neuroblastoma, Retinoblastoma
- Trial name
- NCT01109394
- Where
- 5 sites in United States
- Volunteers
- 6,035 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Solid Tumor
Remote Digital Physiologic Data Collection in Cancer: An MSK Registry Protocol
The purpose of this study is to develop a secure method of collecting physiologic information from patients with cancer. The researchers will use this information to learn more about how physiologic data may relate to cancer…
- Trial name
- NCT05390827
- Where
- United States
- Volunteers
- 3,692 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm
A Novel Molecular Approach to Blood DNA Screening for Cancer: Specificity Assessment (The NOMAD Study)
This study is being done to establish "normal' values for a new blood test and urine test approach to cancer screening. Patients undergo blood and urine sample collection on study. Patients' medical records are reviewed.
- Trial name
- NCT06192875
- Testing
- Non-Interventional Study
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm
Community-Based Physical Activity Intervention for Underserved Cancer Survivors
This clinical trial evaluates a community-based physical activity program for underserved cancer survivors. Cancer and its treatment significantly influence physical, psychosocial, and cognitive functioning.
- Trial name
- NCT06206863
- Testing
- Exercise Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Solid Tumor
A Performance and Bioavailability Study of Entrectinib in Healthy Volunteers.
This study will evaluate the bioavailability, palatability, safety and tolerability of entrectinib in healthy volunteers. Part 1 of the study will explore the performance of entrectinib multi-particle formulation.
- Trial name
- NCT03961100
- Testing
- Entrectinib 600 mg (T1), Entrectinib 600 mg (T2), Entrectinib 200 mg (R)
- Where
- United Kingdom
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Genentech, Inc.
Hepatic Impairment
Pharmacokinetics and Safety Study of Siremadlin (HDM201) in Participants With Mild, Moderate and Severe Hepatic Impairment
The main purpose of this study is to evaluate the effect of varying degrees of impaired hepatic function (by Child Pugh classification) on the plasma PK of siremadlin after a single oral dose.
- Trial name
- NCT05599932
- Testing
- Siremadlin
- Where
- 3 sites in United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Pancreatic Neuroendocrine Tumors, Clear Cell Renal Carcinoma
Near Infrared Technology and Laparoscopic Resection of Pancreatic Lesions: the COLPAN Project
The purpose of this study is to determine whether the use of Near-Infrared Technology can guide the laparoscopic resection of hypervascular neoplasms of the pancreas.
- Conditions
- Pancreatic Neuroendocrine Tumors, Clear Cell Renal Carcinoma, Solid Pseudopapillary Tumors of the Pancreas
- Trial name
- NCT02685553
- Testing
- NIR
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Malignant Solid Neoplasm
Cost Communication and Financial Navigation in Cancer Patients (COSTCOM)
This clinical trial evaluates the effect of Cost Communication and Financial Navigation (CostCOM) intervention on adherence to care and financial burden in cancer patients.
- Trial name
- NCT06295367
- Testing
- Best Practice, Financial Navigation, Interview
- Where
- 391 sites in United States, Guam and 1 more
- Volunteers
- 760 people, healthy volunteers welcome
- Sponsor
- ECOG-ACRIN Cancer Research Group
Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm
Financial Health Educational Program for Increasing Financial Literacy Among Underserved Communities in Western New York
This clinical trial evaluates a financial health educational program to educate and increase knowledge for financial health and well-being, and to ensure access to financial knowledge and resources among underserved community…
- Trial name
- NCT05997589
- Testing
- Behavioral Intervention, Educational Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Breast Carcinoma, Male Breast Carcinoma
Access to Genetic Testing in Underserved Patients With Cancer
This study compares the experiences of people who receive information about genetic testing from a computer-generated character to patients who receive information from a human genetics healthcare provider.
- Conditions
- Breast Carcinoma, Male Breast Carcinoma, Malignant Solid Neoplasm, Metastatic Prostate Carcinoma
- Trial name
- NCT06422455
- Testing
- Best Practice, Educational Intervention, Electronic Health Record Review
- Where
- 2 sites in United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Advanced Solid Tumor
A Food Effect Study of SPH5030 Tablets.
The purpose of this study is to evaluate the food effect of SPH5030 tablets in healthy Chinese adult subjects.
- Trial name
- NCT06372223
- Testing
- SPH5030
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Shanghai Pharmaceuticals Holding Co., Ltd
Solid Tumors, Advanced Solid Tumors
A Two Part Study of RO6870810. Dose-Escalation Study in Participants With Advanced Solid Tumors and Expansion Study in Participants With Selected Malignancies
This is a Phase 1, non-randomized, dose-escalating, open label, multi-center study to be conducted in two parts (Part A and Part B).
- Trial name
- NCT01987362
- Testing
- RO6870810
- Where
- 4 sites in United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Advanced Malignant Solid Tumors
Bioequivalency Study of CM082 Tablet in Healthy Volunteers
The main objective of this study is to evaluate the bioequivalency of two preparations of CM082 tablet in Chinese healthy volunteers.
- Trial name
- NCT04328506
- Testing
- CM082 tablet (test product), CM082 tablet (reference product)
- Where
- China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- AnewPharma
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Positive Activities Intervention to Improve Quality of Life in Collectivist Culture Cancer Patients and Their Caregivers
This clinical trial studies the feasibility of two positive activities in improving quality of life in collectivist culture cancer patients and their caregivers.
- Trial name
- NCT04810052
- Testing
- Behavioral Intervention, Interview, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Melanoma
Culture and Characterization of Circulating Tumor Cells (CTC) in Melanoma and Other Cancers
The purpose of this study is to determine if circulating tumor cells (CTC) can be accurately detected and isolated from the blood of participants with melanoma using novel laboratory techniques.
- Trial name
- CTC (NCT01528774)
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Wolfram Samlowski
Pediatric Solid Tumor, Unspecified, Protocol Specific
Liquid Biopsies in Pediatric Solid Tumors
This study is being done to determine if traces of tumor can be found in the blood before, during, and after patients stop treatment.
- Trial name
- NCT05068583
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Cancer, Hematopoietic and Lymphatic System Neoplasm
A Study of Physical Activity in Cancer Survivors
The purpose of this study is to determine if increasing physical activity (PA) will increase physical functioning, as measured by cardiovascular endurance, muscular strength, and balance in underserved adult cancer survivors > 60…
- Conditions
- Cancer, Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT05988892
- Testing
- Physical Activity
- Where
- 4 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Breast Carcinoma, Colorectal Carcinoma
Assessment of Current Biomarker Testing Practices for Common Solid Cancers in Precision Oncology in the Community Setting
This trial assesses current biomarker testing practices for common solid cancers in precision oncology in the community setting.
- Conditions
- Breast Carcinoma, Colorectal Carcinoma, Community Practice, Lung Carcinoma
- Trial name
- NCT03804255
- Testing
- Survey Administration
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- ECOG-ACRIN Cancer Research Group