Clinical trials: Somatic Symptom Disorder (DSM-5)
Somatic Symptom Disorder (DSM-V)
Effect of Venlafaxine Versus Dosulepin in Pain Predominant Somatic Symptom Disorder
Somatic symptom disorder (SSD) is marked by persistent physical complaints, often involving pain, alongside excessive thoughts or behaviors related to health, which substantially disrupt daily functioning.
- Trial name
- NCT06803485
- Testing
- Venlafaxine, Dosulepin
- Where
- India
- Volunteers
- 84 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Superior Mesenteric Artery Syndrome, Somatic Symptom Disorder (DSM-5)
Fluoxetine in Refractory Superior Mesenteric Artery Syndrome by Targeting Comorbid Somatic Symptom Disorder
The goal of this interventional study is to evaluate whether fluoxetine, a selective serotonin reuptake inhibitor (SSRI), can alleviate core symptoms and reduce the need for surgical intervention in patients with refractory…
- Trial name
- NCT07115472
- Testing
- Fluoxetine
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Depression - Major Depressive Disorder, Generalized Anxiety Disorder
Ultra-brief Psychological Treatments for Emotional Symptoms and Disorders
The main objective of this randomized clinical trial is to study if various modalities of brief (eight sessions) and ultra-brief (four sessions) transdiagnostic cognitive-behavioral treatment work for decrease emotional symptoms…
- Conditions
- Depression - Major Depressive Disorder, Generalized Anxiety Disorder, Generalized Anxiety, Anxiety
- Trial name
- UltraPsyBrief (NCT06909669)
- Testing
- Group ultra-brief transdiagnostic cognitive-behavioral therapy, Group brief transdiagnostic cognitive-behavioral therapy, Individual ultra-brief transdiagnostic cognitive-behavioral therapy
- Where
- 2 sites in Spain
- Volunteers
- 184 people
- Sponsor
- Universidad de Córdoba
Refractory Constipation, Somatic Symptom Disorder (DSM-5)
Evaluation of Fluoxetine for Refractory Constipation With Somatic Symptom Disorder Features
This single-center, randomized, double-blind, placebo-controlled trial evaluates the efficacy and safety of fluoxetine (40 mg/day) versus placebo in 194 adults with refractory chronic constipation exhibiting Somatic Symptom…
- Conditions
- Refractory Constipation, Somatic Symptom Disorder (DSM-5), Functional Constipation (FC)
- Trial name
- REFLECT (NCT06506136)
- Testing
- Fluoxetine
- Volunteers
- 194 people
- Sponsor
- Zhifeng Zhao, PhD
Somatic Symptom Disorder (DSM-V)
Cognitive-Behavioral Therapy Enriched With Emotion Regulation Training for Multiple Somatoform Symptoms
The purpose of this study is to evaluate whether cognitive-behavioral therapy enriched with strategies from emotion regulation training leads to better improvement in somatic symptoms and comorbid problems than…
- Trial name
- ENCERT (NCT01908855)
- Testing
- Cognitive-behavioral therapy + emotion regulation training for patients with multiple somatoform symptoms, Cognitive-behavioral therapy for patients with multiple somatoform symptoms
- Where
- 7 sites in Germany
- Volunteers
- 255 people
- Sponsor
- Philipps University Marburg
Persistent Physical Symptoms (PPS), Functional Somatic Disorder
Emotional Awareness and Expression Therapy for Patients With Persistent Physical Symptoms in Routine Psychiatric Care: A Pilot Study
Emotional Awareness and Expression Therapy (EAET) has emerged as a promising approach for addressing persistent physical symptoms (PPS).
- Conditions
- Persistent Physical Symptoms (PPS), Functional Somatic Disorder, Functional Somatic Syndromes, Somatic Symptom Disorder (DSM-5)
- Trial name
- EAET for PPS (NCT06631911)
- Testing
- Emotional Awareness and Expression Therapy (EAET)
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Daniel Maroti
Somatic Symptom Disorder (DSM-5), Impairment
An Ecological Momentary Intervention for the Reduction of Impairment in Somatic Symptom Disorder
Persistent somatic symptoms significantly impair the daily lives of individuals with Somatic Symptom Disorder (SSD). Negative psychological factors (NPFs), such as catastrophizing and negative affectivity, further compound this…
- Conditions
- Somatic Symptom Disorder (DSM-5), Impairment, Psychological Factors, Persistent Physical Symptoms
- Trial name
- NCT07646509
- Testing
- Music listening, Cognitive reappraisal, No intervention
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- University of Vienna
Functional Constipation (FC), Somatic Symptom Disorder (DSM-5)
Transcranial Alternating Current Stimulation for Refractory Constipation With Somatic Symptom Disorder
The purpose of this randomized, double-blind, placebo-controlled trial is to evaluate the efficacy and safety of transcranial alternating current stimulation (tACS) in adults with refractory functional constipation comorbid with…
- Conditions
- Functional Constipation (FC), Somatic Symptom Disorder (DSM-5), Refractory Constipation
- Trial name
- RELIEF-tACS (NCT07323407)
- Testing
- Transcranial Alternating Current Stimulation
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Somatic Symptom Disorder (DSM-5)
CBT Enriched With Emotion Regulation Training for Multiple Somatoform Symptoms (ENCERT) - A 3-year Follow-up
The purpose of this study is to evaluate whether 3 years after the end of therapy cognitive-behavioral therapy complemented with strategies from emotion regulation training leads to better improvement in somatic symptoms and…
- Trial name
- ENCERT-3YFU (NCT03982524)
- Testing
- Cognitive-behavioral therapy + emotion regulation training for patients with multiple somatoform symptoms, Cognitive-behavioral therapy for patients with multiple somatoform symptoms
- Where
- Germany
- Volunteers
- 255 people
- Sponsor
- Philipps University Marburg