Clinical trials: Sore-throat
Rheumatic Heart Disease in Children
School-based Program for the Prevention of Rheumatic Heart Disease in Endemic Regions
The overall objective of the PREVENT trial is to evaluate the effectiveness of an integrated, school-based program for the prevention of rheumatic heart disease (RHD) in regions with an endemic pattern of RHD.
- Trial name
- PREVENT (NCT06720272)
- Testing
- School nurse program
- Where
- 2 sites in Nepal, Zambia
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Thomas Pilgrim
Pharyngitis Bacterial
A Multi-Site Clinical Evaluation of the ARIES Group A Strep Assay in Symptomatic Patients
A multi-center evaluation to assess the diagnostic sensitivity and specificity of the ARIES Group A Strep Assay will be established through a method comparison using prospectively collected, de-identified, clinical samples…
- Trial name
- NCT03037957
- Testing
- ARIES Group A Strep Assay
- Where
- 5 sites in United States
- Volunteers
- 704 people
- Sponsor
- Luminex Corporation
Streptococcus Pyogenes Infection, Pharyngitis
Clinical Performance of the Checkable Medical At-Home Strep A Test
The Checkable Medical At-Home Strep A Test is a rapid chromatographic immunoassay for the qualitative detection of Group A Strep (GAS) antigens from throat swabs.
- Conditions
- Streptococcus Pyogenes Infection, Pharyngitis, Respiratory Tract Infections
- Trial name
- NCT05107362
- Testing
- untrained lay user performs investigational diagnostic test
- Where
- 22 sites in United States
- Volunteers
- 1,347 people
- Sponsor
- Checkable Medical Inc
Peritonsillar Abscess
Peritonsillar Abscess: Aspiration Versus Tonsillectomy a Chaud
Peritonsillar abscess (PTA) has a relatively high incidence of 41 per 100,000/year in Denmark. In spite of that, there is no regional or national consensus on treatment of PTA.
- Trial name
- NCT03326661
- Testing
- Aspiration, Tonsillectomy a chaud, Penicillin V + metronidazol (Penicillin allergy: Clindamycin alone)
- Where
- Denmark
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Pharyngitis
Testing The Effectiveness Of Celecoxib In Patients With Painful Sore Throat
We are proposing a study in which we utilize and augment the sore throat pain model to assess the analgesic effectiveness of celecoxib compared to placebo in patients with painful pharyngitis under randomized, double-blind…
- Trial name
- NCT00402987
- Testing
- Celecoxib
- Where
- United States
- Volunteers
- 269 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Pharyngitis, Endotracheal Intubation
Incidence and Severity of Postoperative Sore Throat And Intubation Response by Using Different Devices for Endotracheal Intubation
Postoperative sore throat (POST) is a common problem following the use of endotracheal intubation during general anaesthesia. It leads to dissatisfaction and discomfort after surgery and can delay a patient's return to normal…
- Conditions
- Pharyngitis, Endotracheal Intubation, Pain
- Trial name
- NCT02848365
- Testing
- Endotracheal intubation
- Where
- Saudi Arabia
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- King Saud University
Sore Throat
POST: Comparison of Macintosh Laryngoscope vs Video Laryngoscope in Patients Intubated by Anaesthesia Trainee
OBJECTIVES The objective of this study is to compare the frequency of POST in patients intubated by trainee anaesthetist using Video LaryngoscopeTM(VDL) versus Conventional Macintosh Laryngoscope (CL) at a tertiary care hospital…
- Trial name
- POST (NCT04334616)
- Testing
- Video Laryngocope, Macintosh Conventional Laryngocope
- Where
- Pakistan
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Peritonsillar Abscess, Peritonsillar Cellulitis
Transoral Ultrasound Versus no Transoral Ultrasound in Diagnostic Workup of Peritonsillar Abscess
Peritonsillar abscess (PTA) is a collection of pus between the palatine tonsil and the constrictor muscle. PTA is detected by recognizing characteristics during clinical examination: redness, pain, malaise, trismus, and…
- Conditions
- Peritonsillar Abscess, Peritonsillar Cellulitis, Tonsillitis
- Trial name
- NCT07577232
- Testing
- Transoral Ultrasound
- Where
- 3 sites in Denmark
- Volunteers
- 368 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Recurrent Tonsillitis in Children
A Phase I/II to Assess Safety, Tolerability and Efficacy of DL-lactic Acid Syrup in Children With Recurrent Tonsillitis
The study objectives are to evaluate Tonsitin™ (10% Lactic Acid) safety, tolerability and preliminary efficacy, as a potent treatment for Recurrent Tonsillitis in children.
- Trial name
- NCT01988558
- Testing
- DL - Lactic Acid, Raspberry flavored syrup
- Where
- 3 sites in Israel
- Volunteers
- 51 people
- Sponsor
- Yali Pharmaceuticals
Tonsillitis
Comparison of Dexmedetomidine and Midazolam for Prevention of Emergence Delirium in Children
Emergence delirium is a common complication in children after anesthesia. The incidence of emergence delirium is reported upto 50%.
- Trial name
- NCT03337672
- Testing
- Dexmedetomidine, Midazolam
- Where
- South Korea
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Eunah Cho, MD
Pharyngitis
Double-blind Trial to Investigate Efficacy and Tolerance of Ambroxol Lozenges 20 mg in Sore Throat
The aim of this trial is to investigate the efficacy and tolerance of Ambroxol lozenges 20 mg in the treatment of sore throat in patients with acute viral pharyngitis.
- Trial name
- NCT00525044
- Testing
- Ambroxol
- Where
- 4 sites in China
- Volunteers
- 249 people
- Sponsor
- Boehringer Ingelheim
Hoarseness of Voice, Sore-throat
A Prospective,Randomised, Open Label Study for Comparison of the Incidence and Severity of Postoperative Sore Throat (POST) Using C-MAC Video Laryngoscope and Traditional Macintosh Laryngoscope for Intubation
The aim of this study is to compare the incidence of postoperative sore throat after intubation with two different types of laryngoscopes.
- Trial name
- NCT05531617
- Testing
- Intubation
- Where
- India
- Volunteers
- 54 people
- Sponsor
- Seth Gordhandas Sunderdas Medical College
Acute Pharyngitis
A Clinical Trial Investigating the Short-term Relief of Symptoms of Acute Pharyngitis by Treatment With Three Different Doses of MYRAMISTIN™ Oromucosal Spray
In this multi-center, randomized, placebo-controlled, double-blind stuy in which patients with acute pharyngitis will receive Myramistin™ / Placebo, which is provided as a spray.
- Trial name
- MIRA1 (NCT04470089)
- Testing
- Myramistin
- Where
- 12 sites in Austria, Germany
- Volunteers
- 170 people
- Sponsor
- Megainpharm GmbH
Endotracheal Intubation, General Anesthesia
Effect of Different Head Positions During Endotracheal Intubation on Postoperative Sore Throat
The goal of this [ randomized clinical trial] is to [effect of different head positions on the incidence of postoperative sore throat ] in [patients with endotracheal intubation ].
- Trial name
- NCT06059248
- Testing
- the head in the "sniffing position "
- Where
- China
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
General Anesthesia, Laryngeal Mask Airways
Insertion of Laryngeal Mask Airways and Postoperative Sore Throat
When the instruction guidelines of classical laryngeal mask airways (cLMAs) were examined, it was seen that they should be stored between 10 °C and 25 °C.
- Conditions
- General Anesthesia, Laryngeal Mask Airways, Postoperative Sore Throat, Insertion of LMA
- Trial name
- NCT06713343
- Testing
- Laryngeal Mask Airways
- Where
- Turkey (Türkiye)
- Volunteers
- 172 people
- Sponsor
- Ankara City Hospital Bilkent
Pharyngitis
Clinical Trial for Assessment of Safety and Efficacy of a Echinacea/Sage Spray Compared to a Chlorhexidine/Lidocaine Spray in the Treatment of Acute Sore Throats
The aim of the study is to show non-inferiority of an echinacea/sage spray compared to a chlorhexidine/lidocaine-spray in the treatment of acute sore throat during five days of treatment.
- Trial name
- NCT00707902
- Testing
- chlorhexidine/lidocaine, echinacea/sage
- Where
- Switzerland
- Volunteers
- 154 people
- Sponsor
- A. Vogel AG
Streptococcal Sore Throat
In Vitro Diagnostic Device for the Detection of Strep A
The purpose of this trial is to show the accuracy and specificity of the Liat analyzer and assay for detecting Strep A at the point of care lab compared to culture.
- Trial name
- NCT02068469
- Where
- 5 sites in United States
- Volunteers
- 799 people
- Sponsor
- IQuum, Inc.
Laryngeal Mask Airway
Effect of Muscle Relaxants on Postoperative Sore Throat in Video Laryngeal Mask Airway(LMA) Use
Video laryngeal masks (VLMAs) are increasingly used as a minimally invasive alternative in airway management. The use of neuromuscular blocking agents can affect VLMA placement and airway physiology.
- Trial name
- NCT07838051
- Testing
- using rocuronium before vide laryngeal mask airway
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Samsun University
Nausea and Vomiting, Postoperative, Sore-throat
Comparison of Gastric Volume in I-gel and ProSeal Laryngeal Mask Airways
This study was planned to compare the gastric insufflation volume between i jel and ProSeal laryngeal mask airway (LMA) and its relationship with the oropharyngeal sealing pressure and the incidence of postoperative complications…
- Trial name
- NCT07138092
- Testing
- i jel LMA, proseal LMA
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Tonsillitis, Herniorrhaphies
Intelligent Customer-driven Solution for Children and Their Parents Undergoing Day Surgery
This research aims to evaluate the effectiveness of web-based mobile intervention (Icory -Solution) developed to pediatric patients and their parents in the pathway of outpatient surgery treatment in pre-intra- and postoperative…
- Conditions
- Tonsillitis, Herniorrhaphies, Surgery, Children
- Trial name
- NCT04277299
- Testing
- IcorySolution
- Where
- Finland
- Volunteers
- 40 people
- Sponsor
- University of Oulu