Clinical trials: Spastic Cerebral Palsy
Cerebral Palsy
VR Versus Plyometric Exercise on Lower Limb Motor Control and Balance in Spastic Hemiplegic Children
To investigate and compare the effect of Virtual reality and Polymetric exercises on balance, selectivity of the lower extremity and quality of life in children with spastic cerebral palsy.
- Trial name
- NCT07827404
- Testing
- Virtual reality (VR), Plyometric exercises
- Volunteers
- 44 people
- Sponsor
- October 6 University
Activities of Daily Living, Postural Control
Effect of Callisthenic Training on Mobility and ADL Performance in Spastic Diplegic Cerebral Palsy Patients
Almost 2 to 3 out of every 1000 children have Cerebral palsy in Pakistan.Spastic type of CP is dominant about 75%, diplegia (40%) and hemiplegic are (35.5%).Spastic diplegics have tightness of lower limb more than upper…
- Conditions
- Activities of Daily Living, Postural Control, Spasticity, Mobility
- Trial name
- NCT06966076
- Testing
- calisthenic training, Conventional physical therapy group
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Foundation University Islamabad
Hypoxic Brain Damage, Hypoxic Ischaemic Encephalopathy (HIE)
Intranasal AAV9-PHP.eB Gene Therapy in Cerebral Palsy (CP) & Hypoxic Ischemic Encephalopathy (HIE)
This international study, organized by Healing Hope International, is an observational registry designed to collect real-world data on participants living with chronic hypoxic ischemic encephalopathy (HIE) who receive an emerging…
- Conditions
- Hypoxic Brain Damage, Hypoxic Ischaemic Encephalopathy (HIE), Hypoxic Ischaemic Encephalopathy Due to Cardiac Arrest, Hypoxic Ischemic Encephalopathy of Newborn
- Trial name
- GEN-HOPE (NCT07264166)
- Where
- Mexico
- Volunteers
- 25 people
- Sponsor
- Healing Hope International
Cerebral Palsy, Walking, Difficulty
A Motor Learning Intervention to Target Walking Performance in Ambulant Children With Cerebral Palsy
The goal of this clinical trial is to learn if a new therapy approach to improve walking ability in children with Cerebral Palsy is acceptable to the children and the families in a community setting.
- Conditions
- Cerebral Palsy, Walking, Difficulty, Spastic Diplegia, Hemiplegic Cerebral Palsy
- Trial name
- MOBILE (NCT06454656)
- Testing
- MOBILE
- Where
- Ireland
- Volunteers
- 14 people
- Sponsor
- Royal College of Surgeons, Ireland
Spastic Cerebral Palsy
Prospective Studies of the Use of Self Hypnosis, Acupuncture and Osteopathic Manipulation on Muscle Tension in Children With Spastic Cerebral Palsy
We propose to identify patients and families for inclusion in pilot studies of the three modalities. Patients and their families will be asked to participate in these studies.
- Trial name
- NCT00011024
- Testing
- Self Hypnosis, Acupuncture, Osteopathic Manipulation
- Where
- United States
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Cerebral Palsy, Spastic
Effect of Task-Specific Training in an Augmented Reality Context on Upper Limb Function and Activities in Children With Spastic Cerebral Palsy
Children with Cerebral Palsy (CP), a condition that affects movement and coordination, face difficulties in daily activities such as dressing, reaching for objects in high places, and getting up from seats.
- Trial name
- INTERACT (NCT06571929)
- Testing
- INTERACT
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Cerebral Palsy Spastic Diplegia
Effect of Leg Pedalling Exercise From Inclined Position
Statement of the problem:- Does the lower limb pedalling exercise from inclined position improve functional ability and trunk control in children with diplegic cerebral palsy? Null Hypothesis:- There will be no effect of lower…
- Trial name
- NCT06233136
- Testing
- Leg pedalling exercise, The designed physical therapy program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Hemiplegic Cerebral Palsy With Spasticity (Diagnosis)
A Comparative Analysis on Physical Activity Performance and Motor Function of Affected Upper Extremity Before and After a CIMT Program in Young Children With Hemiparetic Cerebral Palsy
This study evaluates CIMT(Constraint Induced Movement Therapy) in the treatment of physical activity performance and motor function of the weaker extremity in young children with cerebral palsy.
- Trial name
- NCT03418519
- Testing
- Constraint Induced Movement Therapy
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Samsung Medical Center
Cerebral Palsy, Spastic
Whole-body Vibration in Spastic Hemiplegic Cerebral Palsy
To target spasticity, balance and mobility whole body vibration exercises along with selected physical therapy is given to experimental group.
- Trial name
- NCT04087330
- Testing
- Group 1 Experimental group, Group 2 Control group
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Recurrent Crying Spells
Recurrent Crying Spells in Cerebral Palsy
This is a study of recurrent crying spells in Spastic Cerebral Palsy patients and their treatment.
- Trial name
- RCSCPSQ (NCT01955655)
- Testing
- Baclofen
- Where
- India
- Volunteers
- 70 people
- Sponsor
- Sathbhavana Brain Clinic
Cerebral Palsy, Spastic
Individualized Virtual Reality in the Upper Extremity Rehabilitation of Hemiparetic Cerebral Palsy
This study aimed to investigate the effect of individualized virtual reality therapy on upper extremity functions of children with hemiparetic cerebral palsy.
- Trial name
- NCT04630678
- Testing
- Virtual Reality Therapy, Conventional Physiotherapy, Activity Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hacettepe University
Cerebral Palsy, Spastic, Rehabilitation
A Pilot Study of Constraint Induced Movement Therapy in Preschool Cerebral Palsy After Botulism Toxin Injection
To establish a pilot randomized, crossover study on applying 2 constraint-induced movement therapy (CIMT) interventions in children with hemiplegic cerebral palsy after botulinum toxin injection during preschool education.
- Trial name
- NCT04179682
- Testing
- 40-hour constraint-induced movement therapy
- Volunteers
- 6 people
- Sponsor
- Changhua Christian Hospital
Cerebral Palsy (CP)
Constraint-induced Movement Therapy Combined With Functional Electrical Stimulation in Children With Cerebral Palsy
This randomized controlled trial aims to compare the effectiveness of Constraint-Induced Movement Therapy (CIMT) combined with Functional Electrical Stimulation (FES) versus CIMT alone in improving upper limb function, reducing…
- Trial name
- CIMT-FES-CP (NCT07587476)
- Testing
- Constraint-Induced Movement Therapy Combined with Functional Electrical Stimulation, Constraint-Induced Movement Therapy
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Montiha Azeem
Spastic Diplegic Cerebral Palsy
Strength Training Using Neuromuscular Electrical Stimulation For Children With Cerebral Palsy
The purpose of this study is to determine if using high-intensity, short-duration, intermittent neuromuscular electrical stimulation (NMES) is better than volitional exercise in increasing quadriceps femoris and triceps surae…
- Trial name
- NCT00356343
- Testing
- NMES Strength Training, Volitional Strength Training
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cerebral Palsy
Motor Learning in People With Cerebral Palsy by Using Virtual Reality.
Cerebral Palsy (CP) is a group of permanent disorders that affect movement and posture due to a non-progressive lesion in the immature brain occurring in fetal brain development or in infancy.
- Trial name
- NCT03348943
- Testing
- Right hemiparesis, right upper limb., Right hemiparesis, left upper limb, Left hemiparesis, left upper limb
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Cerebral Palsy, Spastic
Effect of the Nutritional Support System on Neuromotor Alterations in Patients With Cerebral Palsy
Study to determine the impact of a nutritional support system (NSS) on neuromotor alterations in patients with cerebral palsy.
- Conditions
- Cerebral Palsy, Spastic, Malnutrition
- Trial name
- NSS-PC (NCT05648422)
- Testing
- Probiotics, NSS Nutritional Support System, Deworming
- Where
- Mexico
- Volunteers
- 144 people
- Sponsor
- Anahuac University
Sjogren-Larsson Syndrome (SLS)
Sjogren-Larsson Syndrome: Natural History, Clinical Variation and Evaluation of Biochemical Markers
Sjogren-Larsson syndrome (SLS) is a rare genetic disease in which patients typically exhibit ichthyosis (dry, scaly skin), intellectual disability, spasticity, seizures and a distinctive maculopathy.
- Trial name
- SLS (NCT01971957)
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Nebraska
Healthy, Spastic Hemiparesis
Soleus Loading Response During Walking
Stroke survivors experience motor deficits, weak voluntary muscle activations, and low weight-bearing capacity that impair ambulation.
- Conditions
- Healthy, Spastic Hemiparesis, Stroke
- Trial name
- NCT05436366
- Testing
- Soleus loading response in able-bodied participants, Soleus loading response in participants with hemiparesis
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Victor H. Duenas
Lower Limb and Combined Lower Limb and Upper Limb Spasticity Due to Cerebral Palsy
Long-term Open-label Study of Botulinumtoxin Type A to Treat Spasticity of Leg(s) or Leg(s) and Arm in Cerebral Palsy
The purpose of this study is to determine whether injections of Botulinum toxin type A into muscles of the leg(s) or of leg(s) and one arm are safe in treating children/adolescents (age 2-17 years) long-term with increased muscle…
- Trial name
- NCT01905683
- Testing
- IncobotulinumtoxinA (16-20 Units per kg body weight)
- Where
- 43 sites in Austria, Czechia and 10 more
- Volunteers
- 370 people
- Sponsor
- Merz Pharmaceuticals GmbH
Gait, Spastic
Weight Distribution Asymmetry in Relation to Speed During Gait in Children With Spastic Cerebral Palsy.
Background: Improving walking ability is one of the major concerns in therapeutic interventions for children with cerebral palsy.
- Trial name
- NCT04636424
- Testing
- assesment of gait
- Where
- Egypt
- Volunteers
- 114 people
- Sponsor
- Cairo University