Clinical trials: Spastic Cerebral Palsy
Cerebral Palsy Spastic Diplegia
Oculomotor Training in Spastic Diplegia: Effects on Postural Stability and Motor Proficiency
This randomized clinical trial investigates the effect of oculomotor training on postural stability and motor proficiency in children with spastic diplegia.
- Trial name
- NCT07731074
- Testing
- Oculomotor Training, Conventional Physiotherapy
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Cairo University
Cerebral Palsy, Hemiplegia
Effect of Coordinative Locomotor Training in Children With Cerebral Palsy
Cerebral palsy is a brain disorder that affects how children move their bodies. Children with spastic hemiplegic CP have stiffness on one side of the body, making it hard to walk and balance.
- Conditions
- Cerebral Palsy, Hemiplegia, Spastic cp
- Trial name
- CLT-PHYSIO-CP (NCT07651995)
- Testing
- Coordinative Locomotor Training, Conventional Physiotherapy
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- University of Faisalabad
Cerebral Palsy (CP), Spastic Diplegia Cerebral Palsy
Comparison of Synchronous and Asynchronous Action Observation Therapy in Children With Cerebral Palsy
The aim of this study is to compare the effects of synchronous and asynchronous action observation therapy (AOT) on balance, gait, and functional capacity in children with cerebral palsy (CP).
- Conditions
- Cerebral Palsy (CP), Spastic Diplegia Cerebral Palsy, Spastic Hemiplegic Cerebral Palsy, Neurodevelopmental Disorder (Diagnosis)
- Trial name
- NCT07114731
- Testing
- Synchronous Action Observation Therapy, Asynchronous Action Observation Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Istanbul University - Cerrahpasa
Bilateral Spastic Cerebral Palsy, Cerebral Palsy
Effect of Treadmill Gait Training Combined With Conventional Physiotherapy on Gait Performance and Functional Mobility in Children With Bilateral Spastic Cerebral Palsy: A Randomized Controlled Trial
Cerebral palsy is a neurological condition that affects movement, muscle control, and walking ability in children. Children with bilateral spastic cerebral palsy often experience increased muscle stiffness, difficulty with…
- Conditions
- Bilateral Spastic Cerebral Palsy, Cerebral Palsy, Spasticity Due to Cerebral Palsy, Gait Abnormality
- Trial name
- GAIT-CP (NCT07683338)
- Testing
- Treadmill Gait Training, Conventional Physiotherapy
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Syeda Khatoon e Jannat Welfare Foundation
Spastic Cerebral Palsy (sCP)
Cuevas Medek Exercises to Improve Postural Control and Balance in Children With Spastic Cerebral Palsy
This study aims to evaluate the effects of Cuevas Medek Exercises on postural control and balance in children with spastic cerebral palsy.
- Trial name
- NCT07403162
- Testing
- Cuevas medek exercises, Conventional Therapy
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Spastic Diplegic Cerebral Palsy
Effects of Vestibular Stimulation in Addition to Conventional Physiotherapy in Improving Gross Motor Function and Mobility in Children With Spastic Diplegic Cerebral Palsy
This was a RCT to determine and compare the effects of vestibular stimulation in addition to conventional physical therapy on gross motor function and mobility in children with spastic diplegic cerebral palsy.
- Trial name
- NCT07712315
- Testing
- Experimental Group A received Vestibular Stimulation along with Conventional therapy., Control Group B received Conventional physiotherapy alone.
- Where
- Pakistan
- Volunteers
- 58 people
- Sponsor
- Ibadat International University, Islamabad
Spina Bifida, Cerebral Palsy
Assessing Transition Practices for Children With Disabilities: Pathways to a Successful Adulthood
Transition to adult care is a purposeful and structured movement of youth with complex disabilities from child centered to adult oriented services. This complex and potentially challenging period requires careful planning.
- Conditions
- Spina Bifida, Cerebral Palsy, Spinal Cord Injury, Spastic Paraplegia
- Trial name
- NCT07706517
- Testing
- Chart review, Semi-structured interview
- Where
- France
- Volunteers
- 128 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Cerebral Palsy, Spastic Diplegia
Effects of Proprioceptive Neuromuscular Facilitation and Task-Oriented Training on Upper Extremity Function in Children With Spastic Diplegic Cerebral Palsy
Children with spastic diplegic cerebral palsy often experience upper extremity impairments, including reduced coordination, muscle control, and functional hand use, which limit independence in daily activities.
- Trial name
- PNF-TOT-CP (NCT07694804)
- Testing
- Proprioceptive Neuromuscular Facilitation (PNF), Task-Oriented Training (TOT), Combined Proprioceptive Neuromuscular Facilitation and Task-Oriented Training
- Where
- Pakistan
- Volunteers
- 63 people
- Sponsor
- Ibadat International University, Islamabad
Bilateral Spastic Cerebral Palsy
Kinesio Taping Versus Electrical Stimulation on Dysphagia in Bilateral Cerebral Palsy
The purpose of this study will be to compare the effect between kinesiotaping and neuromuscular electrical stimulation on dysphagia in children with bilateral spastic cerebral palsy.
- Trial name
- NCT07695350
- Testing
- Structured Oromotor Exercises, Kinesio Taping, Neuromuscular Electrical Stimulation
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Spastic Hemiplegic Cerebral Palsy
Effect of Lower Extremity Modified Constraint-induced Movement Therapy on Locomotion in Children With Hemiplegia
To determine the effect of modified constraint-induced movement therapy on spatial and temporal gait parameters in children with hemiplegia.
- Trial name
- NCT07686809
- Testing
- Modified constraint-induced movement therapy, Conventional physical therapy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Spastic Cerebral Palsy (sCP)
Bimanual Training Versus Unilateral Task Specific Training in Children With Spastic Hemiplegic Cerebral Palsy
Cerebral palsy is one of the most common childhood neurological disorders and often results in weakness, poor coordination, and stiffness (spasticity) in one side of the body in children with spastic hemiplegic cerebral palsy.
- Trial name
- BUST-CP (NCT07437274)
- Testing
- Bimanual Training, Unilateral Task-Specific Training
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Montiha Azeem
Cerebral Palsy, Spastic Diplegic Cerebral Palsy
Comparing Mixed Reality and Physical Therapy to Improve Balance and Coordination in Adolescents With Spastic Diplegic Cerebral Palsy
This randomized controlled trial aims to compare the effectiveness of fully immersive Mixed Reality (MR) combined with standard physical therapy versus standard physical therapy alone in improving balance and coordination among…
- Trial name
- NCT07685327
- Testing
- Meta Quest Pro Mixed Reality System, Standard Physical Therapy
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Ibadat International University, Islamabad
Cerebral Palsy, Cerebral Palsy, Spastic
Effects of Hand and Arm Bimanual Intensive Therapy Including Lower Extremity in Spastic Cerebral Palsy
Cerebral palsy (CP), particularly the spastic diplegic subtype, is characterized by motor impairments such as spasticity and mobility limitations.
- Trial name
- HABIT-ILE (NCT07253857)
- Testing
- GROUP -A , Hand and Arm Bimanual Intensive Therapy Including Lower Extremity, GROUP-B , Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Spastic Diplegia
Action Observation Therapy in Children With Spastic Diplegia
The aim of this study is to compare the effect of live versus video action observation training (AOT) on balance and gait in children with spastic diplegia.
- Trial name
- AOT/CP (NCT07651111)
- Testing
- A selected physical therapy program, Live action observation training (AOT), Video action observation training (AOT)
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Cerebral Palsy (CP), Spastic Quadriplegia
Impact of Task-Specific Electrical Stimulation on Upper Limb Functional Motor Skills in Children With Spastic Quadriplegia
Cerebral palsy is a non-progressive lesion of the brain occurring before 2 years of age resulting in disorders of posture and movement.( Ostensjo S, 2004)( Keles MN, 2018) .
- Conditions
- Cerebral Palsy (CP), Spastic Quadriplegia, Upper Limb Function, Functional Motor Disorder
- Trial name
- NCT07631390
- Testing
- The Chattanooga Continuum™, Designed Physical therapy program
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Kafrelsheikh University
Muscle Spasticity, Hypertonia, Muscle
Single and Multiple Ascending Dose Study of MTR-601 in Healthy Individuals
To assess the safety and tolerability of single and multiple doses of MTR-601 in normal healthy volunteers under fed and fasted conditions. To evaluate the plasma and urine pharmacokinetics (PK) of MTR-601.
- Conditions
- Muscle Spasticity, Hypertonia, Muscle, Cerebral Palsy, Multiple Sclerosis
- Trial name
- NCT06117020
- Testing
- MTR-601
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Motric Bio
Diplegic Cerebral Palsy With Spasticity, Cerebral Palsy, Spastic, Diplegic
Impact of rTMS Combined With Neurorehabilitation on Lower Extremity Motor Function and Spasticity in Children With Spastic Diplegic Cerebral Palsy
Cerebral palsy (CP) is widely recognized as the most prevalent cause of lifelong physical disability emerging in childhood across most global populations.
- Conditions
- Diplegic Cerebral Palsy With Spasticity, Cerebral Palsy, Spastic, Diplegic, Transcranial Magnetic Stimilation, Cerebral Palsy (CP)
- Trial name
- NCT07488429
- Testing
- TMS
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ankara City Hospital Bilkent
Cerebral Palsy, Spastic
Core Strength for Head Control and Quality of Life in Cerebral Palsy
The goal of this observational study is to examine the effect of an 8-week therapist-assisted core muscle strengthening program on head control, trunk stability, functional core strength, quality of life, and automatic righting…
- Trial name
- NCT07613515
- Testing
- Core Strength Training
- Where
- Saudi Arabia
- Volunteers
- 38 people
- Sponsor
- Cairo University
Spastic Diplegic Cerebral Palsy
Sensory Walkway and Gait in Children With Diplegic Cerebral Palsy
This study aims to evaluate the effect of sensory walkway training on gait performance in children with spastic diplegic cerebral palsy.
- Trial name
- SWGCP (NCT07595744)
- Testing
- Conventional Physical Therapy Program, Sensory Walkway Training
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Cairo University
Hemiparesis, Paraparesis
Immediate Effects On Gait and Spasticity After The Use Of Passive Kinesiotherapy Equipment In The Lower Limbs Of Neurological Patients
Undergo assessment of muscle tone (Ashworth Scale), gait (BAIOBIT) and risk of falling (Timed Up and Go) before using the device; Use the device on the spastic lower limb(s) for 30 minutes; Go through the same assessment carried…
- Conditions
- Hemiparesis, Paraparesis, Tetraparesis, Cerebral Palsy
- Trial name
- NCT06696040
- Testing
- Passive mobilization using a device
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Fernanda Trubian