Clinical trials: Spastic Diplegia
Major Depressive Disorder
IM and IV SPL026 Drug Product in Healthy Participants
The goal of this clinical trial is to test SPL026 given via injection into a muscle in healthy volunteers.
- Trial name
- NCT05644093
- Testing
- SPL026 IV, SPL026 IM
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Small Pharma Ltd
Cigarillo Flavor
Attitudes and Perceptions Attitudes and Smoking Perceptions in the Real Environment -II
This multi-method project will recruit young adults who currently use cigarillos and examine the effects of different flavored cigarillo types (concept, characterizing, tobacco) on three measures of tobacco product appeal…
- Trial name
- ASPIRE-II (NCT06668350)
- Testing
- Smoking outcomes
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Bladder Cancer, Colorectal Cancer
The Molecular Predisposition to Hereditary Nonpolyposis Colon Cancer (HNPCC)
The goal of this study is to understand factors which may influence risk for colorectal and other cancers in families. These factors include genetic variability, in combination with diet and lifestyle.
- Conditions
- Bladder Cancer, Colorectal Cancer, Endometrial Cancer, Kidney Cancer
- Trial name
- NCT01447199
- Testing
- Health and Diet Questionnaire
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Diplegia, Spastic
Eye-Hand Coordination in Children With Spastic Diplegia
This study will examine how the brain controls eye-hand coordination (visuomotor skills) in children with spastic diplegia and will determine whether impairment of this skill is related to the learning difficulties in school that…
- Trial name
- NCT00024791
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Yoga, Preschool Children
The Effect of Yoga on Gaining Sleep Habits in Children
This study was planned to determine the effect of the "Little Yogis Doing Yoga" Program, which will be created within the scope of the research, on getting children aged 5-6 years old to sleep habits.
- Conditions
- Yoga, Preschool Children, Sleep Habit
- Trial name
- NCT05828290
- Testing
- Child Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Tobacco Use
Little Cigar and Cigarillo Warnings to Reduce Tobacco-Related Cancers and Disease - Eye Tracking
The goal of this research is to determine how removal of little cigar and cigarillo (LCC) flavor descriptors on packaging impacts attention and affective responses to LCC warnings.
- Trial name
- NCT06546618
- Testing
- LCC pack stimuli images
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Suicide, Trauma, Psychological
Wakȟáŋyeža (Little Holy One)
The overall goal of this study is to develop, adapt and evaluate an intergenerational prevention intervention, named "Wakȟáŋyeža (Little Holy One)," with Native American caregivers on a Northern Plains reservation and the…
- Conditions
- Suicide, Trauma, Psychological, Parenting
- Trial name
- NCT04201184
- Testing
- Newly created cultural components, adapted Family Spirit lessons, adapted CETA modules, Active nutrition control
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cerebral Palsy (CP), Spastic Diplegia Cerebral Palsy
Effects of High-Velocity Passive Stretch on Spasticity, Function, and Muscle Structure in Spastic CP Children
One of the traditional exercises applied to cerebral palsy (CP) is passive stretching exercises. Passive stretching exercises can be applied to these patients at various speeds.
- Conditions
- Cerebral Palsy (CP), Spastic Diplegia Cerebral Palsy, Spastic Hemiplegic Cerebral Palsy
- Trial name
- NCT07007858
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Behavior, Anxiety
Tutorial of Clinical Trial Registration
The present study aimed to determine whether infants disorders of regulation of states are associated with perinatal anxiety, and further to explore the efficacy of the behavioral intervention in enhancing positive interactions…
- Trial name
- CTREG (NCT03481452)
- Testing
- psychotherapy
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Anti-Mullerian Hormone Deficiency, Post Partum Hemorrhage
Anti-Mullerian Hormone (AMH) is a Marker for Ovarian Reserve. There Are Many Studies About AMH Changes in Ovarian Surgery, But Little is Known for Other Surgeries. We Seek to Investigate the Hormone Variations Before and After Uterine Artey Ligation for Postpartum Hemorrage (PPH)
Anti-Mullerian hormone (AMH) is a marker for ovarian reserve. There are many studies about AMH changes in ovarian surgery, but little is known for other surgeries.
- Trial name
- NCT03907605
- Testing
- anti- mullerian hormone
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Cerebral Palsy, Cerebral Palsy Spastic Diplegia
Evaluation of the Applicability and Reliability of the Three Meter Backwalk Test in Children With Cerebral Palsy (CP)
Cerebral palsy (CP) is a non-progressive disturbance in the development of movement and posture that occurs in the prenatal or postnatal period, causing activity limitations.
- Conditions
- Cerebral Palsy, Cerebral Palsy Spastic Diplegia, Hemiplegic Cerebral Palsy, Gait, Hemiplegic
- Trial name
- NCT04653363
- Testing
- assessments
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sanko University
Anxiety, Paediatric
Comparison of Efficacy of Little Lovely Dentist, Dental Song and Tell-show-do Techniques in Alleviating Dental Anxiety in Paediatric Patients
To evaluate the efficacy of different techniques for the reduction of dental anxiety in pediatric patients. Generally, anxiety amongst paediatric patients is higher as compared to adult patients.
- Conditions
- Anxiety, Paediatric, Dental Anxiety, Behaviour
- Trial name
- NCT04833478
- Testing
- Anxiety
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Altamash Institute of Dental Medicine
Typical Development
Promoting Motor Development in Infants and Toddlers Through Education and Early Detection
The "Little Movers" study promotes healthy motor development in early childhood by providing education to caregivers and professionals in the child's environment and by implementing early detection strategies for motor delays.
- Trial name
- Little-Movers (NCT07091474)
- Testing
- Educational Workshops for Parents and Early Educators, Motor Development Assessment in Children 0-36 Months
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Cerebral Palsy
Brain Control of Movements in Cerebral Palsy
This study will examine how the brain controls movements in patients with certain types of cerebral palsy. In healthy people, one side of the body usually controls movements on the other side of the body.
- Trial name
- NCT00076596
- Where
- 2 sites in United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Childhood Obesity
The Bottle Optimization Testing Tiny Little Eaters Study
The researchers will study how babies respond to bottle nipples with different flow rates over a few days, and how this may affect how much milk they drink, their feeding patterns, and their sleep.
- Trial name
- BOTTLE (NCT07665983)
- Testing
- Feeding
- Where
- United States
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Obesity, Insulin Resistance
Diabetes Prevention Program for Obese Latino Youth
The purpose of this study is to examine the effects of 12 week lifestyle intervention on diabetes risk in obese Latino adolescents.
- Conditions
- Obesity, Insulin Resistance, Diabetes
- Trial name
- ELSC (NCT02039141)
- Testing
- Every Little Step Counts Intervention
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Anxiety Acute, Anxiety Fear
Paediatric Peri-operative Anxiety: Does the Little Journey App Help?
To evaluate the clinical effectiveness of a virtual reality psychological preparation app at reducing peri-operative anxiety and its associated sequelae in children aged 3-12 years old undergoing ambulatory surgery compared to…
- Conditions
- Anxiety Acute, Anxiety Fear, Peri-operative, Psychological Distress
- Trial name
- NCT03797716
- Testing
- Little Journey app
- Where
- 17 sites in United Kingdom
- Volunteers
- 596 people, healthy volunteers welcome
- Sponsor
- University College, London
Cerebral Palsy, Spastic Diplegia
Evaluation of Brain MRI Changes in Cerebral Palsy Patients
Cerebral palsy (CP) is a neurodevelopmental syndrome characterized by sensorimotor impairment that arises during early childhood defined as a static insult to the developing brain.
- Conditions
- Cerebral Palsy, Spastic Diplegia, Spastic Quadriplegia, Spastic Hemiplegia
- Trial name
- NCT07433647
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Columbia University
Cerebral Palsy, Spastic Diplegia
Walking Inclined Plane
The adaptations in kinematics and muscle activity, investigated by 3D gait analysis and dynamic electromyography recordings, will be studied in children with bilateral spastic cerebral palsy during level walking, and before and…
- Trial name
- NCT02988557
- Testing
- walking on a treadmill with a sloped surface, treadmill
- Where
- France
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Spastic Diplegic Cerebral Palsy
Repetitive Transcranial Magnetic Stimulation Versus Botulinum Injection on Spasticity on Children With Diplegic Cerebral Palsy
This trial will enroll 75 children with spastic diplegic cerebral palsy both matched in age, sex, degree of disability and cognitive functions with the same exclusion criteria undergoing the same physical therapy.
- Trial name
- NCT06218316
- Testing
- botulinum toxin A, Transcranial Magnetic Stimulation, Rehabilitation Training Protocol
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- MTI University