Clinical trials: Spastic Diplegia
Motor Skills Disorders, Child Development
Identification of Neuromotor Signs in Preschool Children Suspected of Developmental Coordination Disorder
This prospective study aimed to detect neuromotor signs early in preschool children suspected of Developmental Coordination Disorder (DCD).
- Conditions
- Motor Skills Disorders, Child Development, Child, Preschool
- Trial name
- NCT06269796
- Testing
- Little Developmental Coordination Disorder Questionnaire (LDCDQ), Bruininks- Oseretsky Test of Motor Proficiency 2nd Edition (BOT-2)
- Where
- Greece
- Volunteers
- 424 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Smoking
Nicotine Metabolism and Little Cigars
This study examines the effects of smoking little cigars in different groups of smokers. The investigators are focusing on differences in how smokers' bodies break down and eliminate nicotine from their systems.
- Trial name
- NCT01898559
- Testing
- Switch to smoking only little cigars
- Where
- United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Anti-Mullerian Hormone Deficiency, Post Partum Hemorrhage
Anti-Mullerian Hormone (AMH) is a Marker for Ovarian Reserve. There Are Many Studies About AMH Changes in Ovarian Surgery, But Little is Known for Other Surgeries. We Seek to Investigate the Hormone Variations Before and After Uterine Artey Ligation for Postpartum Hemorrage (PPH)
Anti-Mullerian hormone (AMH) is a marker for ovarian reserve. There are many studies about AMH changes in ovarian surgery, but little is known for other surgeries.
- Trial name
- NCT03907605
- Testing
- anti- mullerian hormone
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Bladder Cancer, Colorectal Cancer
The Molecular Predisposition to Hereditary Nonpolyposis Colon Cancer (HNPCC)
The goal of this study is to understand factors which may influence risk for colorectal and other cancers in families. These factors include genetic variability, in combination with diet and lifestyle.
- Conditions
- Bladder Cancer, Colorectal Cancer, Endometrial Cancer, Kidney Cancer
- Trial name
- NCT01447199
- Testing
- Health and Diet Questionnaire
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Gait Disorders in Children, Cerebral Palsy Spastic Diplegia
Comparison of Walking Parameters Between Idiopathic Toe Walking and Independent Walking Diparetic Cerebral Palsy
The aim of the observational study is to compare static, kinematic and kinetic parameters with normal gait parameters in cases with Idiopathic toe walking (ITW) and Diparetic Cerebral Palsy (DCP) who have Gross Motor Function…
- Trial name
- NCT06142721
- Testing
- 3D Gait Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Biruni University
Spastic Diplegic Cerebral Palsy, Hemiplegic Cerebral Palsy
Strength Training in Children With Spastic Diplegic and Hemiplegic Cerebral Palsy Receiving Botulinum Toxin
To estimate the effectiveness of strength training after administration of botulinum toxin in children with spastic diplegic cerebral palsy and hemiplegic cerebral palsy on muscle volume and gross motor function.
- Trial name
- NCT04177186
- Testing
- Strength training, Strength training with botulinum toxin
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Asir John Samuel
Hypoxic-Ischemic Encephalopathy, Neonatal Encephalopathy
Healthy Little Eyes
The purpose of this research study is to gather more information on how eye injury is related to a baby's future development and see if eye function and brain test results can be used, along with current measures, to better…
- Conditions
- Hypoxic-Ischemic Encephalopathy, Neonatal Encephalopathy, Encephalopathy
- Trial name
- NCT05971446
- Testing
- Visual Evoked Potential (VEP), Electroretinogram (ERG)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Cerebral Palsy (CP), Spastic Diplegia Cerebral Palsy
Effects of High-Velocity Passive Stretch on Spasticity, Function, and Muscle Structure in Spastic CP Children
One of the traditional exercises applied to cerebral palsy (CP) is passive stretching exercises. Passive stretching exercises can be applied to these patients at various speeds.
- Conditions
- Cerebral Palsy (CP), Spastic Diplegia Cerebral Palsy, Spastic Hemiplegic Cerebral Palsy
- Trial name
- NCT07007858
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Major Depressive Disorder
IM and IV SPL026 Drug Product in Healthy Participants
The goal of this clinical trial is to test SPL026 given via injection into a muscle in healthy volunteers.
- Trial name
- NCT05644093
- Testing
- SPL026 IV, SPL026 IM
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Small Pharma Ltd
Cerebral Palsy, Spastic Diplegia
Evaluation of Brain MRI Changes in Cerebral Palsy Patients
Cerebral palsy (CP) is a neurodevelopmental syndrome characterized by sensorimotor impairment that arises during early childhood defined as a static insult to the developing brain.
- Conditions
- Cerebral Palsy, Spastic Diplegia, Spastic Quadriplegia, Spastic Hemiplegia
- Trial name
- NCT07433647
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Columbia University
Behavior, Anxiety
Tutorial of Clinical Trial Registration
The present study aimed to determine whether infants disorders of regulation of states are associated with perinatal anxiety, and further to explore the efficacy of the behavioral intervention in enhancing positive interactions…
- Trial name
- CTREG (NCT03481452)
- Testing
- psychotherapy
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Spastic Diplegic Cerebral Palsy
Repetitive Transcranial Magnetic Stimulation Versus Botulinum Injection on Spasticity on Children With Diplegic Cerebral Palsy
This trial will enroll 75 children with spastic diplegic cerebral palsy both matched in age, sex, degree of disability and cognitive functions with the same exclusion criteria undergoing the same physical therapy.
- Trial name
- NCT06218316
- Testing
- botulinum toxin A, Transcranial Magnetic Stimulation, Rehabilitation Training Protocol
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- MTI University
Childhood Obesity
The Bottle Optimization Testing Tiny Little Eaters Study
The researchers will study how babies respond to bottle nipples with different flow rates over a few days, and how this may affect how much milk they drink, their feeding patterns, and their sleep.
- Trial name
- BOTTLE (NCT07665983)
- Testing
- Feeding
- Where
- United States
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Suicide, Trauma, Psychological
Wakȟáŋyeža (Little Holy One)
The overall goal of this study is to develop, adapt and evaluate an intergenerational prevention intervention, named "Wakȟáŋyeža (Little Holy One)," with Native American caregivers on a Northern Plains reservation and the…
- Conditions
- Suicide, Trauma, Psychological, Parenting
- Trial name
- NCT04201184
- Testing
- Newly created cultural components, adapted Family Spirit lessons, adapted CETA modules, Active nutrition control
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Yoga, Preschool Children
The Effect of Yoga on Gaining Sleep Habits in Children
This study was planned to determine the effect of the "Little Yogis Doing Yoga" Program, which will be created within the scope of the research, on getting children aged 5-6 years old to sleep habits.
- Conditions
- Yoga, Preschool Children, Sleep Habit
- Trial name
- NCT05828290
- Testing
- Child Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Obesity, Insulin Resistance
Diabetes Prevention Program for Obese Latino Youth
The purpose of this study is to examine the effects of 12 week lifestyle intervention on diabetes risk in obese Latino adolescents.
- Conditions
- Obesity, Insulin Resistance, Diabetes
- Trial name
- ELSC (NCT02039141)
- Testing
- Every Little Step Counts Intervention
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Cerebral Palsy, Spastic Diplegia
Walking Inclined Plane
The adaptations in kinematics and muscle activity, investigated by 3D gait analysis and dynamic electromyography recordings, will be studied in children with bilateral spastic cerebral palsy during level walking, and before and…
- Trial name
- NCT02988557
- Testing
- walking on a treadmill with a sloped surface, treadmill
- Where
- France
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Cigarillo Flavor
Attitudes and Perceptions Attitudes and Smoking Perceptions in the Real Environment -II
This multi-method project will recruit young adults who currently use cigarillos and examine the effects of different flavored cigarillo types (concept, characterizing, tobacco) on three measures of tobacco product appeal…
- Trial name
- ASPIRE-II (NCT06668350)
- Testing
- Smoking outcomes
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma