Clinical trials: Spastic Hemiplegia
Stroke
Effectiveness of Two Techniques in Injection Site Spotting for Botulinum Toxin Injections: Echography or Electro Stimulation.
Botulinum toxin injections are an effective treatment of limb spasticity after stroke. Different tracking techniques are used to locate a proper injection spot.
- Trial name
- NCT01935544
- Testing
- Botulinum toxin injection
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Clermont-Ferrand
Hemiplegia, Spasticity, Muscle
Investigation of the Effects of Upper Extremity Botulinum Toxin Application on Forearm Muscle Thickness and Motor Recovery in Patients With Hemiplegia
In this study, we aimed to examine the effects of the botulinum toxin (BoNT) application on muscle thickness and motor recovery in stroke patients.
- Trial name
- NCT07083752
- Testing
- Botulinum toxin application
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Abant Izzet Baysal University
Hemiplegia and/or Hemiparesis Following Stroke
Exercise to Improve Sleep and Quality of Life in Stroke Patients Receiving Botulinum Toxin Treatment
This study aimed to investigate the contribution of aerobic exercise programmes to improving sleep quality, quality of life, and functional status, alongside conventional rehabilitation, in stroke patients who had received…
- Trial name
- NCT07369453
- Testing
- Aerobic exercise training using a cycle ergometer
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Spasticity as Sequela of Stroke, Spastic Hemiplegia
Modulation of Upper Limb Spasticity Post-Stroke
Stroke is one of the commonest causes of severe disability in adults. Stroke often results in spasticity and motor impairments in the upper limb.
- Conditions
- Spasticity as Sequela of Stroke, Spastic Hemiplegia, Upper Extremity Dysfunction
- Trial name
- NCT05069480
- Testing
- Virtual reality-based training equipment., Traditional physical therapy program
- Where
- Saudi Arabia
- Volunteers
- 38 people
- Sponsor
- Umm Al-Qura University
Hemiplegic Cerebral Palsy
Effect of Extracorporeal Shock Wave and Peripheral Magnetic Stimulation on Spastic CP Children
Hypotheses: There will be an effect of radial extracorporeal shock wave therapy and peripheral magnetic stimulation on the following parameters, in children with spastic hemiplegia: Wrist flexors spasticity.
- Trial name
- NCT05607134
- Testing
- selected physical and occupational therapy program, Radial Extracorporeal Shock Wave, Peripheral magnetic stimulation
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Cerebral Palsy
Brain Reorganization Following Constraint-Induced Therapy in Children With Cerebral Palsy
This study will examine how therapy changes the way the brain controls movements in children with cerebral palsy. Normally, one side of the brain controls movements in the opposite side of the body.
- Trial name
- NCT00100503
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Post-stroke Spasticity, Spasticity Post-Traumatic Brain Injury
Dysport® Adult Lower Limb Spasticity Follow-on Study
The purpose of this research study is to assess the long term safety of Dysport® in hemiparetic subjects with lower limb spasticity due to stroke or traumatic brain injury over repeated treatment cycles.
- Trial name
- NCT01251367
- Testing
- Botulinum toxin type A
- Where
- 50 sites in United States, Australia and 9 more
- Volunteers
- 352 people
- Sponsor
- Ipsen
Stroke
Improving Holding Function of the Hemiplegic Hand
Relevant to patients with spastic hemiparesis in the hand and upper limb, this pilot project proposes to measure the effects of botulinum toxin injections through observation of performance on a functional task known as 'hand as…
- Trial name
- NCT02459951
- Testing
- clenched fist
- Volunteers
- 10 people
- Sponsor
- Nathaniel Mayer
Stroke
Effectiveness of Matrix Rhythm Therapy on Increased Muscle Tone, Balance and Gait Parameters in Stroke Survivors
Matrix-Rhythm-Therapy(MRT) has been included in neuro-rehabilitation program for stroke patients to regulate increased muscle tone. There are no controlled studies with large sample size on the efficacy of MRT on spasticity.
- Trial name
- NCT04213417
- Testing
- Bobath therapy and Matrix Rhythm Therapy, Bobath therapy
- Volunteers
- 30 people
- Sponsor
- Pamukkale University
Stroke, Spastic Hemiplegia
Effects of Neuromuscular Electrical Stimulation on Flexor Spasticity and Function in Stroke Patients
In this study, the investigators aimed to determine the effects of botulinum neurotoxin type A injections for wrist and finger flexor spasticity and neuromuscular electrical stimulation therapy applied to wrist and finger flexors…
- Trial name
- NCT06725069
- Testing
- Neuromuscular Electrical Stimulation, Control (Standard treatment)
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Hemiplegia
Comparison of the Effects of Extracorporeal Shock Wave Therapy and Dry Needing
Effective treatment of spasticity after stroke is a very important and serious problem. Some of the therapeutic approach include physiotherapy and medication.
- Trial name
- NCT05952830
- Testing
- ESWT group, DN group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Neurological Rehabilitation, Stroke
Evaluation of Hand Strength and Spasticity in Hemiplegic Patients
The aim in this study is to evaluate spasticity and hand grip strength with a finger hand robot in the Turkish population.
- Conditions
- Neurological Rehabilitation, Stroke, Upper Extremity Problem
- Trial name
- NCT05662878
- Testing
- Assessment of Hand Strength and Spasticity
- Where
- Turkey (Türkiye)
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Spasticity, Cerebrovascular Accident
Efficacy and Safety Study of MYOBLOC® in the Treatment of Adult Upper Limb Spasticity
Phase 2/3, randomized, double-blind, placebo-controlled, single-treatment, multicenter trial assessing the efficacy and safety of MYOBLOC for the treatment of upper limb spasticity in adults followed by an open-label extension…
- Conditions
- Spasticity, Cerebrovascular Accident, Multiple Sclerosis, Traumatic Brain Injury
- Trial name
- NCT04815967
- Testing
- Phase 2; Low Dose MYOBLOC (10,000 Units), Phase 2; High Dose MYOBLOC (20,000 Units), Phase 3; MYOBLOC
- Where
- 9 sites in United States, Hungary and 1 more
- Volunteers
- 32 people
- Sponsor
- Solstice Neurosciences, LLC, a subsidiary of MDD US Operations, LLC
Stroke, Spastic Hemiparesis
Hand Rehabilitation Using Botulinum Toxin and Functional Electrical Stimulation-pilot Study
The investigator tried to find out possibility of functional improvement using botulinum toxin injection targeting finger flexor spasticity with functional electrical stimulation among chronic stroke patients who did not show any…
- Conditions
- Stroke, Spastic Hemiparesis, Spasticity as Sequela of Stroke
- Trial name
- NCT03549975
- Testing
- Botulinum Toxin Type A 100 unit/Vial (Product)
- Volunteers
- 20 people
- Sponsor
- National Rehabilitation Center, Seoul, Korea
Stroke, Hemiplegia, Spastic
The Effect of Extracorporeal Shock Wave Therapy After Botulinum Toxin Type A Injection for Post-stroke Spasticity
There are few studies on whether botulinum toxin treatment and extracorporeal shock wave therapy are more effective than botulinum toxin alone treatment for post-stroke spasticity.
- Conditions
- Stroke, Hemiplegia, Spastic, Muscle Spasticity
- Trial name
- NCT05889026
- Testing
- Extracorporeal shock wave therapy, Botulinum toxin treatment
- Where
- South Korea
- Volunteers
- 16 people
- Sponsor
- Korea University Guro Hospital
Stroke, Hemiplegia
Robot-Assisted Therapy in Chronic Stroke Patients
Considering the paucity of studies on robotic hand therapy, larger-scale and long-term follow-up studies are needed. The aim in this study is to demonstrate the effectiveness of robot-assisted hand therapy in patients with…
- Trial name
- NCT06692829
- Testing
- robotic rehabilitation, conventional rehabilitation
- Volunteers
- 80 people
- Sponsor
- Afyonkarahisar Health Sciences University
Hemiplegia, Spastic
Inter-rater Reliability of the Australian Spasticity Assessment Scale (ASAS) in Post-stroke Spasticity
The reliability of the Australian Spasticity Assessment Scale (ASAS) has been reported to be not high enough in adult patients with acquired brain damage.
- Trial name
- NCT04613661
- Testing
- Australian Spasticity Assessment Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Izmir Katip Celebi University
Cerebral Palsy Spastic Hemiplegic
Effectiveness of Universal Exercise Unit Exercise on Upper Limb Strength Using Biodex Isokinetic
The aim of the study is to determine the role of designed program in the universal exercise unit on upper limb function and strength in children with spastic hemiplegia.
- Trial name
- UEU/CP (NCT07233031)
- Testing
- Experimental, Control (Standard treatment)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Hemiplegia, Spastic
Motor Learning Approaches From Working on a Vertical Surface in Hemiplegic Children's Upper Limb Motor Skills
Working on a vertical surface is one of the best activities children can do to make themselves more successful in many areas as an infant which builds all those foundational skills required for the all-important task of…
- Trial name
- NCT05596513
- Testing
- motor learning and occupational therapy, Motor Learning Approaches From Working on a Vertical Surface
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Omnya Samy Abdallah Ghoneim
Upper Limb Spasticity
Randomised, Evaluation-blinded, Crossover, Controlled Study Assessing Dynamic Hand Splinting in Adults With Post-stroke Hemiplegia (Orthox)
Upper limb spasticity is currently mainly managed with local toxin treatments. Recent studies suggested combining botulinum toxin injections with splinting to optimise rehabilitation in spastic patients.
- Trial name
- ORTHOX (NCT02888548)
- Testing
- botulinum toxins (Dysport°) alone, orthosis (Saebo Strech°) + botulinum toxins (Dysport°) combined
- Where
- France
- Volunteers
- 1 people
- Sponsor
- CHU de Reims