Clinical trials: Spastic Paresis
Spasticity, Muscle, Spinal Cord Injuries
Long-term Efficacy of Spasticity-correcting Surgery and Botulinum Toxin Injections for Upper Limb Spasticity Treatment
Spasticity - a variety of motor over-activity and part of the upper motor neuron syndrome - is a common cause of impaired motor function after brain injuries of different etiologies.
- Conditions
- Spasticity, Muscle, Spinal Cord Injuries, Traumatic Brain Injury, Stroke
- Trial name
- NCT03910101
- Testing
- Hand surgery and intensive rehabilitation
- Where
- Sweden
- Volunteers
- 34 people
- Sponsor
- Vastra Gotaland Region
Paraparesis, Gait Disorders, Neurologic
Effect of Electromagnetic Field Therapy on Balance and Gait in Paraparetic Patients
This study will investigate whether adding electromagnetic field therapy (EMT) to a standard physical therapy program is more effective than physical therapy alone for improving balance and walking ability in paraparetic…
- Conditions
- Paraparesis, Gait Disorders, Neurologic, Postural Balance Disorders
- Trial name
- EMT-BG (NCT07196956)
- Testing
- Low-Frequency Electromagnetic Field Therapy (0.5 Hz)
- Where
- Saudi Arabia
- Volunteers
- 30 people
- Sponsor
- MTI University
Cerebral Palsy, Paraparesis, Spastic
Effects of Therapeutic Music Combined With Loaded Sit-to-Stand Resistance Exercise for Children With Spastic Diplegia
The purpose of study is to investigate the effects of PSE Music with a "home-based" loaded STS exercise program on the functional strength, gross motor function, daily participation, exercise involvement, motor control, and gait…
- Trial name
- NCT01367327
- Testing
- Loaded sit-to-stand exercise, Synchronized music
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- National Taiwan University Hospital
Stroke, Walking, Difficulty
Agonist and Antagonist Muscle Activations in the Lower Limbs During Walking After Central Nervous System Injury
The retrospective study investigates the part of responsibility of neuromuscular disorders associated with chronic hemiparesis in walking impairment.
- Conditions
- Stroke, Walking, Difficulty, Spasticity/Paresis
- Trial name
- NEUROGAIT (NCT06107556)
- Testing
- Gait analysis
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Henri Mondor University Hospital
Stroke, Hemiparesis
"Comparison of Therapist-Led and Robot-Assisted Arm Therapy in Subacute Stroke Rehabilitation"
This study aims to compare the outcomes of upper limb motor therapy conducted by a physiotherapist with robot-assisted therapy using the Luna EMG device in patients in the subacute phase after stroke.
- Conditions
- Stroke, Hemiparesis, Muscle Spasticity, Upper Extremity Dysfunction
- Trial name
- NCT07002463
- Testing
- Luna EMG, Therapist-assisted upper limb training
- Where
- Poland
- Volunteers
- 58 people
- Sponsor
- Wroclaw University of Health and Sport Sciences
Spasticity/Paresis, Cerebral Palsy
Efficacy of Extracorporeal Shock Wave Therapy in Children With Cerebral Palsy
Spastic plantar and palmar flexion deformities are very common in children with cerebral palsy (CP). These deformities usually involve spasticity of the plantar or palmar muscle complexes, weakness of the antagonist dorsiflexor…
- Trial name
- NCT06128616
- Testing
- ESWT, Botulinum Toxin Type A, Serial Casting
- Volunteers
- 40 people
- Sponsor
- Kocaeli University
Stroke
The Impact of Botox® During Robotic Rehabilitation of the Wrist Following Stroke
The purpose of this study is to see whether treating subjects for wrist rehabilitation following stroke with Botox® and robotic therapy is more effective than treatment with robotic therapy alone and no Botox®.
- Trial name
- NCT01088230
- Testing
- Botox®, saline solution
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- New York Presbyterian Hospital
Primary Lateral Sclerosis, Hereditary Spastic Paraplegia
Nuclear Magnetic Spectroscopy Imaging to Evaluate Primary Lateral Sclerosis, Hereditary Spastic Paraplegia and Amyotrophic Lateral Sclerosis
This study will use a magnetic resonance imaging technique called nuclear magnetic spectroscopy (H-MRS) to define the pathology and progression of primary lateral sclerosis, hereditary spastic paraplegia and amyotrophic lateral…
- Conditions
- Primary Lateral Sclerosis, Hereditary Spastic Paraplegia, Amyotrophic Lateral Sclerosis
- Trial name
- NCT00023075
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Multiple Sclerosis
Botulinum Toxin in Patients With Spastic Lower Limb Paresis Associated With Multiple Sclerosis
Spastic paraparesis is one of the most disabling functional deficits in the population with multiple sclerosis between 18 and 80 years of age and at any functional level.
- Trial name
- NCT04595045
- Testing
- Botulinum toxin type A infiltrations
- Where
- 2 sites in Spain
- Volunteers
- 84 people
- Sponsor
- Aránzazu Vázquez Doce
Cerebral Palsy, Upper Extremity Paresis
Effectiveness of Armeo Spring Robotic Therapy in the Function of the Upper Limb of Children With Unilateral Spastic Cerebral Palsy Infiltrated With Botulinum Toxin
Background: Unilateral spastic cerebral palsy (CP) generates an impact on daily activities, mainly due to the functional limitation of the affected upper limb.
- Trial name
- NCT04554238
- Testing
- Armeo spring, Occupational Therapy
- Where
- Chile
- Volunteers
- 23 people
- Sponsor
- Sociedad Pro Ayuda del Niño Lisiado
Hemiparesis, Paraparesis
Immediate Effects On Gait and Spasticity After The Use Of Passive Kinesiotherapy Equipment In The Lower Limbs Of Neurological Patients
Undergo assessment of muscle tone (Ashworth Scale), gait (BAIOBIT) and risk of falling (Timed Up and Go) before using the device; Use the device on the spastic lower limb(s) for 30 minutes; Go through the same assessment carried…
- Conditions
- Hemiparesis, Paraparesis, Tetraparesis, Cerebral Palsy
- Trial name
- NCT06696040
- Testing
- Passive mobilization using a device
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Fernanda Trubian
Vascular Accident, Brain, CVA (Cerebrovascular Accident)
Effect of Brain Stimulation on Stepping Performance in Stroke Survivors and Healthy Adults
Participants are being asked to participate in a research study conducted by Shih-Chiao Tseng, PT, Ph.D. at Texas Woman's University.
- Conditions
- Vascular Accident, Brain, CVA (Cerebrovascular Accident), Gait, Hemiplegic, Spastic Lower Extremity Weakness
- Trial name
- Gait (NCT04437251)
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Texas Woman's University
Spinal Cord Injured, Post-stroke
Effects of an Eccentric Muscle Strengthening Protocol on Force Moment, Muscle Activation and Plantar Flexor Structure of Patients With Central Nervous System Injuries.
Neurological disorders [such as Cerebral Vascular Accident (CVA) or Spinal Cord Injury (SCI)] are among the most costly health problems to society in industrialized countries.
- Trial name
- RenfExc (NCT06099340)
- Testing
- muscle-strengthening program
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Nantes University Hospital
Hemiparesis
Plantar Flexor Eccentric Training in Chronic Hemiparesis
The goal of this clinical trial is to assess the effects of a plantar flexor eccentric training on muscle health of these muscles and teir descending command in chronic spastic hemiparesis.
- Trial name
- EXC-AVC (NCT06790446)
- Testing
- Eccentric training group (ECC), Conventional therapy
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Neuroloco
Spastic Hemiplegic Cerebral Palsy, Upper Extremity Paresis
The Effects of Upper Extremity Robotic Rehabilitation in Children With Spastic Hemiparetic Cerebral Palsy
Aims: To investigate the effects of upper extremity robotic rehabilitation on upper extremity skills and functional independence level in patients with hemiparetic Cerebral Palsy (hCP).
- Conditions
- Spastic Hemiplegic Cerebral Palsy, Upper Extremity Paresis, Robotic Rehabilitation
- Trial name
- NCT06352762
- Testing
- Conventional physiotherapy, Robotic Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Izmir Bakircay University
Stroke, Stroke, Ischemic
Passive Tactile Stimulation for Stroke Rehabilitation
Stroke can lead to weakness and spasticity in the arm or hand. The purpose of this study is to optimize the design of gentle vibratory stimulation delivered to the hands of individuals with chronic stroke, and explore the effect…
- Conditions
- Stroke, Stroke, Ischemic, Stroke Hemorrhagic, Spasticity as Sequela of Stroke
- Trial name
- PTS (NCT03814889)
- Testing
- Vibration pattern, No vibration
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Stanford University
Muscle Spasticity, Healthy
Physiologic Studies of Spasticity
This study will provide information about changes that occur in the motor neurons of the spinal cord (the nerve cells that control the muscles) when the motor cortex (the region of the brain that controls movement) is unable to…
- Trial name
- NCT00014976
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Brain-injury
Effectiveness of Aquatic Theraphy in Spasticity: Watsu and Halliwick
Treatment with ACD patients will be carried out through the application of aquatic therapies, being the Halliwick Concept and the Watsu Method together with a time of immersion in hot water.
- Trial name
- NCT05151497
- Testing
- Experimental group:Halliwick + Método Watsu, Control group:Halliwick
- Where
- 3 sites in Spain
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Cadiz
Stroke, Hemiparesis
Mechanism of Action of Focal Extracorporeal Shock Waves as a Treatment of Upper Limb Stroke Spasticity: a Pilot Study
Spasticity, common after a stroke, aggravates the patient's motor impairment causing pain and limitation in daily activities such as eating, dressing and walking.
- Conditions
- Stroke, Hemiparesis, Hemiplegia, Spasticity as Sequela of Stroke
- Trial name
- SASHA (NCT06311526)
- Testing
- Extracorporeal Shockwave Therapy
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- Istituto Auxologico Italiano
Stroke, Muscle Spasticity
Effects of Cryotherapy on Ankle Movements and Gait of Spastic Hemiparetic Subjects
The stroke has been described as the third cause of death and main cause of disability in the worldwide population. About 60% of the survivors are able to walk following the rehabilitation process, however deficits on lower limbs…
- Trial name
- NCT02736747
- Testing
- Cryotherapy
- Where
- Brazil
- Volunteers
- 16 people
- Sponsor
- Carolina Carmona de Alcântara