Clinical trials: Spastic Paresis
Stroke, Muscle Spasticity
Altering Activation Patterns Post-stroke
This study evaluates a new rehabilitation approach for stroke survivors in the chronic phase of recovery in which the combination of drug therapy (cyproheptadine) and active movement practice (AMP) is used to encourage increased…
- Conditions
- Stroke, Muscle Spasticity, Hemiparesis
- Trial name
- NCT02418949
- Testing
- Cyproheptadine, Active Movement Practice (AMP), Passive Cyclical Stretching
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Shirley Ryan AbilityLab
Children, Cerebral Palsy
Reliability and Validity of Strength Measurements of the Lower Limbs in Children With Bilateral Spastic Cerebral Palsy.
Specific musculo-tendinous adaptations in children with cerebral palsy (CP) have an influence on muscle strength and consequently on functional behavior and participation.
- Conditions
- Children, Cerebral Palsy, Muscle Weakness
- Trial name
- NCT03818152
- Testing
- Functional strength assessment
- Where
- Belgium
- Volunteers
- 24 people
- Sponsor
- University Ghent
Spastic Cerebral Palsy
Therapeutic Potential of Myofascial Structural Integration in Children With Cerebral Palsy
The investigators hypothesize that children with spastic cerebral palsy will show greater improvements in gross motor function, associated developmental skills and growth after the 3 months of myofascial structural integration…
- Trial name
- NCT01815814
- Testing
- Rolfing / Myofascial Structural Integration
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Stanford University
Stroke, Hemiparesis;Poststroke/CVA
Muscle Oxygenation and Spasticity in Hemiparetic Stroke Patients
Conditions such as hemiparesis, sensory and motor impairment, perceptual impairment, cognitive impairment, aphasia, and dysphagia may be observed after stroke.
- Conditions
- Stroke, Hemiparesis;Poststroke/CVA, Spasticity as Sequela of Stroke
- Trial name
- NCT06362954
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ankara Medipol University
Stroke, Hemiparesis
CONSTRAINT-INDUCED MOVEMENT THERAPY (CIMT) VS. MIRROR THERAPY (MT) ON HAND FUNCTION AND SPASTICITY IN PATIENTS WITH HEMIPARESIS
This study aimed to compare the effects of Constraint-Induced Movement Therapy (CIMT) and Mirror Therapy (MT) on hand function and spasticity in individuals with hemiparesis.
- Conditions
- Stroke, Hemiparesis, Hemiparesis After Stroke
- Trial name
- NCT06910904
- Testing
- Constraint-Induced Movement Therapy (CIMT), Mirror Therapy (MT)
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- University of Lahore
Spastic Cerebral Palsy, Physical Therapy Modalities
Effectiveness of Whole-Body Vibration
Cerebral Palsy is the most common cause of severe physical disability in childhood and may present difficulties and limitations that will have an impact on their independence and integration in all social areas.
- Conditions
- Spastic Cerebral Palsy, Physical Therapy Modalities, Vibration; Exposure, Lower Extremity Weakness, Spastic
- Trial name
- WBVibration (NCT06330311)
- Testing
- Physiotherapy
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Complutense de Madrid
Myopathy, Muscle Weakness
Reliability of Cardiac Troponins for the Diagnosis of Myocardial Infarction in the Presence of Skeletal Muscle Disease
Visits to the emergency department (ED) for chest pain are extremely common and require a safe, rapid and efficacious treatment algorithm to exclude a possible AMI.
- Conditions
- Myopathy, Muscle Weakness, Muscle Damage, Muscle Spasticity
- Trial name
- H&M (NCT03660969)
- Where
- 5 sites in Austria, Switzerland
- Volunteers
- 797 people
- Sponsor
- University Hospital, Basel, Switzerland
Spasticity as Sequela of Stroke, Stroke
Transcutaneous Spinal and Peripheral Stimulation and Wrist Robotic Therapy for Patients With Spastic Stroke
The purpose of this study is to investigate if two courses of five consecutive sessions of noninvasive spinal stimulation paired with peripheral nerve stimulation at the forearm provided by an investigational device (Doublestim™/…
- Conditions
- Spasticity as Sequela of Stroke, Stroke, Stroke Sequelae, Hemiplegia, Spastic
- Trial name
- NCT04113525
- Testing
- MyoRegulator™ System
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Northwell Health
Spastic Paresis, Stroke
GOAT (Gait Observation of Achilles Tendon)
The purpose of this study is to evaluate the mechanical properties of the Achilles tendon (stiffness, length, volume) and the force production capacities of the gastrocnemius medialis muscle in patients with spastic paresis…
- Conditions
- Spastic Paresis, Stroke, Spinal Cord Injury
- Trial name
- GOAT (NCT07467382)
- Testing
- 3D Gait Analysis, Ultrasound, Dynamometry
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Hemiparesis
Comparison of Two Rehabilitation Strategies in Patients With Hemiparesis One Year or More After Stroke
In the situation of motor limitations that people often experience after stroke, current health systems cannot provide for the daily amount and duration of high intensity muscle stretch and motor training that would be required…
- Trial name
- NEURORESTORE (NCT02202954)
- Testing
- Guided Self-rehabilitation Contract
- Where
- France
- Volunteers
- 124 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stroke, Hemiparesis
Fully Remote Use of IpsiHand Device in Hemiparetic Stroke
BCI-REHAB was a randomized clinical trial comparing an at-home brain-computer interface therapy system versus an at-home exercise program for upper-extremity rehabilitation in the chronic phases of stroke.
- Conditions
- Stroke, Hemiparesis, Spasticity as Sequela of Stroke, Brain Computer Interface
- Trial name
- NCT05965713
- Testing
- Neurolutions IpsiHand Upper Extremity Rehabilitation System, Home Exercise rehabilitation regimen Program (HEP)
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Neurolutions, Inc.
Spastic Parapareses
Transcutaneous Direct Current Stimulation of the Spinal Cord for Treatment of Spasticity in Multiple Sclerosis
The current research is aimed at using Transcutaneous Spinal Direct Current Stimulation (tSDCS) as complementary therapeutic tool in the treatment of spasticity in multiple sclerosis.
- Trial name
- NCT04287244
- Testing
- Transcutaneous Spinal Direct Current Stimulation
- Volunteers
- 40 people
- Sponsor
- Lebanese American University
Stroke Rehabilitation, Cerebrovascular Stroke
Error Augmentation Motor Learning Training Approach in Stroke Patients
Deficits in upper limb (UL) functional recovery persist in a large proportion of stroke survivors. Understanding how to obtain the best possible UL recovery is a major scientific, clinical and patient priority.
- Conditions
- Stroke Rehabilitation, Cerebrovascular Stroke, Muscle Spasticity, Upper Extremity Paresis
- Trial name
- NCT04378946
- Testing
- Intensive physical rehabilitation type training, Robotic system for supporting and monitoring arm motion, Actigraph Activity Monitor
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- McGill University
Stroke, Hemiparesis
Biomarkers for Prediction of Hand Function After Stroke - The ProHand Study
The overall aim is to identify key determinants for recovery of hand function after stroke by applying newly developed hand function measures together with MRI measurements of the lesioned cerebral structures.
- Trial name
- ProHand (NCT02878304)
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Danderyd Hospital
Upper Limb Paresis, Spastic Hemiplegia
Functional Electrical Stimulation With Mirror Therapy on Upper Limb Functions and Quality of Life in Hemiplegic Children
The goal of this clinical trial is to To investigate the combined effect of functional electrical stimulation and mirror therapy on:Quality of life and UL function in children with hemiplegia,Their age will be ranged from 5 to 10…
- Trial name
- FESMT (NCT07135739)
- Testing
- funcional Electrical stimulation combined with mirror therapy, Physical therapy program
- Volunteers
- 40 people
- Sponsor
- Rabab Mustafa Abdo
Spasticity/Paresis
Stereotactic Radiosurgery (SRS) in Malignant Spasticity and Hypertonia
This is a pilot, experimental, monocentric study. The main objective of the study is to evaluate whether stereotactic radiotherapy is able to reduce symptomatic spasticity from a clinical point of view, and therefore induce an…
- Trial name
- NCT06309810
- Testing
- Radiotherapy
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- IRCCS Sacro Cuore Don Calabria di Negrar
Cerebral Palsy, Muscle Hypertonia
Hypertonia in Patients With Cerebral Palsy
This study will classify types of hypertonia in patients with cerebral palsy and determine if the classifications are reasonable in relation to the functional task of walking. Hypertonia is an abnormal increase in muscle tension.
- Trial name
- NCT00123708
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cerebral Palsy (CP), Spasticity Due to Cerebral Palsy
Effect of Botulinum Toxin Type A on Motor Function in Children With Cerebral Palsy
Project Identification and Researchers Title: "Changes in functionality and quality of life when applying the botulinum toxin type A infiltration protocol in children and adolescents with cerebral palsy of the spastic hemiparesis…
- Conditions
- Cerebral Palsy (CP), Spasticity Due to Cerebral Palsy, Hemiparesis
- Trial name
- NCT07034547
- Testing
- Botulinum toxin infiltration
- Where
- Chile
- Volunteers
- 30 people
- Sponsor
- Instituto Teletón Chile
Spasticity as Sequela of Stroke, Stroke
Prevalence of Postural Patterns of Upper Extremity.
A high number of patient with stroke develops spasticity of the upper extremity, this clinical sign of damage of 1 motoneuro (MN), causes postures and patterns of abnormal movement, due to the hyperexcitability of the MN and the…
- Conditions
- Spasticity as Sequela of Stroke, Stroke, Upper Extremity Paresis
- Trial name
- Patterns (NCT03588832)
- Testing
- Evaluation Upper Extremity patterns.
- Where
- Chile
- Volunteers
- 600 people
- Sponsor
- Universidad de La Frontera
Stroke, Arm
Enhancing Recovery of Arm Movement in Stroke Patients
Many people who have had a stroke have problems recovering the use of their affected arm and these problems may persist for a long time.
- Conditions
- Stroke, Arm, Paresis
- Trial name
- ENHANCE (NCT02725853)
- Testing
- tDCS, personalized practice, non-personalized practice
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McGill University