Clinical trials: Specific Language Impairment
Dyslexia, Dyslexia, Developmental
Impact of Non-invasive Brain Stimulation on Learning Novel Spoken Words
The purpose of the proposed study is to use transcranial magnetic stimulation (TMS) to evaluate a neurobiological model of spoken word learning in older youth.
- Conditions
- Dyslexia, Dyslexia, Developmental, Learning; Developmental Disorder, Reading
- Trial name
- NCT06387615
- Testing
- Active cTBS
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Georgia State University
Developmental Language Disorder, Specific Language Impairment
Retrieval-based Word Learning in Developmental Language Disorder: Adaptive Retrieval Schedule
Children with developmental language disorder (DLD; also referred to as specific language impairment) experience a significant deficit in language ability that is longstanding and harmful to the children's academic, social, and…
- Conditions
- Developmental Language Disorder, Specific Language Impairment, Language Development
- Trial name
- NCT06995014
- Testing
- Retrieval-based word learning: Standard retrieval practice schedule, Retrieval-based word learning: Adaptive retrieval practice schedule
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Purdue University
Developmental Dyslexia
Prediction and Intervention in Developmental Dyslexia
The long-term goal of this study is to improve prediction of poor reading outcome at preschool age by using a combination of behavioural and neuroimaging measures and to evaluate a specific computerized training program to…
- Trial name
- LEXI (NCT02217696)
- Testing
- Computerized reading training
- Where
- Switzerland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Inattention, Cognitive Training
RECOGNeyes Gaze-Control Training
RECOGNeyes is a computer game developed by members of the research team to improve attention in people who find it hard to "keep their eyes on the task".
- Conditions
- Inattention, Cognitive Training, Cognitive Control, Oculomotor Dysfunction
- Trial name
- NCT06691646
- Testing
- Gaze-control training game
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Language Impairment, Down Syndrome
Phenotypic Specific Communication Intervention for Children With Down Syndrome
Children with Down syndrome (DS) have greater difficulty acquiring expressive language than is predicted by their general cognitive abilities and language comprehension (Miller, 1999).
- Trial name
- Merck (NCT02158390)
- Testing
- Jasper-EMT with words and AAC
- Where
- 2 sites in United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Dyslexia, Gait Disorders, Neurologic
Dynamic Gait Index in Children With Dyslexia
The aim of the present study is to investigate reliability in dyslexic children and compare it with healthy peers.
- Trial name
- NCT04235465
- Testing
- Dynamic Gait Index
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Specific Language Impairment
Specific Language Impairment (SLI) in Children May Caused by Epileptic Brain Activity
The objective of this study was to find if there is a possible association and the impact of epilepsy and epileptiform activity in children with SLI.
- Trial name
- NCT04141332
- Testing
- EEG was recorded by EEG Machines
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Mansoura University Hospital
Developmental Language Disorder
Language Outcomes, Mechanisms, and Trajectories in Adults With and Without Developmental Language Disorder
The investigators' overall objective is to characterize the long-term outcomes of Developmental Language Disorder (DLD) in adulthood and to identify specific cognitive mechanisms mediating these outcomes.
- Trial name
- NCT06898671
- Testing
- Eye-Tracking in Visual World Paradigm
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Neurofibromatosis Type 1, Reading Disabilities
Neurobiology and Treatment of Reading Disability in NF-1
The goal of this trial is to determine if children with neurofibromatosis type 1 who have reading disabilities respond the same way-both behaviorally and neurobiologically-to specialized treatment programs as children with…
- Trial name
- NCT00624234
- Testing
- Tutoring Program I, Tutoring Program II
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Developmental Language Disorder, Language Delay
Using Neuroimaging and Behavioral Assessments to Understand Late Talking
Late talkers (LT), representing 10-20% of children under 3, demonstrate hallmark syntax and vocabulary deficits similar to preschoolers with developmental language disorder.
- Conditions
- Developmental Language Disorder, Language Delay, Language Development
- Trial name
- NCT06156865
- Testing
- Intervention to address late talking
- Where
- 2 sites in Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Dyslexia, Reading Problem
Neurofeedback Training for Dyslexia
The study aims at testing a Neurofeedback (NF) training specifically designed for inducing a functional hemispheric imbalance of the tempo-parietal regions in individuals with dyslexia.
- Trial name
- NCT04989088
- Testing
- ProComp5 Infiniti System w/BioGraph Infiniti Software, ProComp5 Infiniti System w/recorded videos
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Perinatal Condition, Neurodevelopmental Disorders
Perinatal and Psychological Correlates of Neurodevelopmental Disorders in Children.
The goal of this observational study is to investigate perinatal, cognitive and social-emotional correlates of neurodevelopmental disorders and educational difficulties in children and adolescents.
- Conditions
- Perinatal Condition, Neurodevelopmental Disorders, Social Functioning, Child Development
- Trial name
- NCT06215092
- Testing
- Psychological assessment
- Where
- Poland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Bartosz M. Radtke
Preterm Birth, Developmental Dyslexia
Reading-FREE Markers for Early Detection of Developmental Dyslexia
This study aims to identify early signs of developmental dyslexia (DD) and other reading difficulties in children born preterm, using behavioral, cognitive, and brain imaging data collected before reading problems typically…
- Trial name
- FREE-DD (NCT07072104)
- Testing
- Multidomain Neuropsychological and Reading-Free Screening Tool (RSFT) Assessment Battery - Grade 2, MRI - Grade 2, Multidomain Neuropsychological and Reading-Free Screening Tool (RSFT) Assessment Battery - Grade 3
- Where
- Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Dyslexia
Reading Problems in Children Living in Urban Areas
The first line of defense against reading disabilities is good classroom reading instruction. This study describes how characteristics of students, teachers, and instruction relate to academic achievement in inner-city…
- Trial name
- NCT00065832
- Testing
- Reading Instruction
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Developmental Dyslexia, Reading Problem
Personalization of Visual Characters and Text-to-Speech (TTS) to Support Learning in Students With Reading Difficulties
Previous research has shown the importance of font type, size and spacing to facilitate text reading in dyslexia. A special automatized procedure was designed to select the most favorable parameters for both text visualization…
- Trial name
- NCT06947512
- Testing
- Seleggo Test
- Where
- 3 sites in Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Dyslexia, Dysphasia
Developmental Language Difficulties: Behavioural and Electrophysiological Studies
This study will help to better characterize oral and written language disorders and determine if these disorders are continuous or not.
- Trial name
- LANGAGE (NCT02872870)
- Testing
- auditory lexical decision task, electroencephalogram
- Where
- 3 sites in Belgium, France
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Lille Catholic University
Developmental Language Disorder
Contextual Word Learning in Children With Developmental Language Disorder
Many children have developmental language disorder, which makes it difficulty to learn language, including vocabulary, and results in ongoing academic and social difficulties.
- Trial name
- NCT05988190
- Testing
- Contextual Word Learning Intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Binghamton University
Developmental Dyslexia
Morphofunctional Imaging and Developmental Dyslexia
Developmental dyslexia is a frequent learning disability. The aim of this study is to analyze cortical thickness and phonological treatment in right handed adults with developmental dyslexia.
- Trial name
- PHR04-CH/DYS (NCT00254644)
- Testing
- Morphological and functional MRI
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Developmental Language Disorder
Semantic Learning Deficits in School Age Children With Developmental Language Disorder
School age children with developmental language disorder (DLD) have known semantic learning deficits but what is less well understood is why semantic learning is difficult for these children.
- Trial name
- NCT04508699
- Testing
- semantic learning
- Where
- United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Agraphia
Visual Perceptual Motor Training on Kindergarteners
The study aims to investigate the effects of different visuomotor training programs on children's visuomotor skills and handwriting performance.
- Trial name
- NCT05795738
- Testing
- Chinese character-based visuomotor training program, traditional visuomotor training program
- Where
- Taiwan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital