Clinical trials: Specificity
HIV Infections
Safety and Effectiveness of a Three-Drug Combination Treatment for Recently Infected or Converted HIV Patients
The purpose of this study is to determine the safety and effectiveness of stavudine (d4T), didanosine (ddI), and BMS-232632 when given early in the course of HIV infection.
- Trial name
- NCT00007202
- Testing
- Atazanavir, Stavudine, Didanosine
- Where
- 5 sites in United States, Brazil
- Volunteers
- 55 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Lymphedema, Breast Cancer Stage II
Study the Usefulness of Bio-impedance Spectroscopy in the Early Assessment of Breast Cancer Related Lymphoedema
The goal of the study is to investigate the use of bio-impedance spectroscopy in the assessment of breast cancer related lymphoedema in patients operated with lumpectomy or mastectomy, axillary lymph node dissection and…
- Conditions
- Lymphedema, Breast Cancer Stage II, Early Disease Onset
- Trial name
- NCT01599039
- Where
- Netherlands
- Volunteers
- 80 people
- Sponsor
- Nij Smellinghe Hosptial
Asthma
A Study to Evaluate the Sensitivity and Specificity of Inhaled Methacholine in Bronchial Provocation Test
A multicenter, open-label study to evaluate the sensitivity and specificity of inhaled methacholine in bronchial provocation test
- Trial name
- NCT05634473
- Testing
- Methacholine Chloride
- Where
- 12 sites in China
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Neoplasia
The Sensitivity and Specificity of Sniff Dog as a Tool in Diagnosing the Suspected Tumor Patients
Previous studies have demonstrated that sniff dogs can identify cancer patients from healthy subjects through sniffing exhaled breath air or blood or serum or urine or feces.
- Trial name
- NCT02049658
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Chang-Qing Gao
Hemophagocytic Lymphohistiocytoses, Lymphoma
Sensitivity and Specificity of Cytokines in the Diagnosis of Lymphoma-associated HLH
Lymphoma-associated hemophagocytic lympohistiocytosis is a refractory immune disorder with high mortality. Early identification and diagnosis of lymphoma-associated HLH has become the key to improve the prognosis of…
- Trial name
- NCT05600959
- Testing
- cytokine
- Where
- China
- Volunteers
- 89 people
- Sponsor
- Beijing Friendship Hospital
Immuno-modulation, Immuno-suppression
Analysis of the Specificity and Persistence of Nasal Immune Responses to Respiratory Viral Antigens in Immunocompromised and Healthy Cohorts
The goal of this observational study is to characterize nasal mucosal immunity to respiratory viruses, such as SARS-CoV-2, in immunocompromised individuals and healthy volunteers.
- Conditions
- Immuno-modulation, Immuno-suppression, Immunocompromised Patients, Healthy Subjects
- Trial name
- NCT07295535
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Meridians
The Moxibustion-Induced Thermal Transport Effect Between The Heart And Lung Meridians
Although some important progresses were made in the field of the meridian research, no breakthroughs have been achieved. Besides,there are some problems in meridian researches.
- Trial name
- NCT05330403
- Testing
- Moxibustion
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Zhejiang Chinese Medical University
Bronchoalveolar Lavage Fluid, Sensitivity and Specificity
Aspergillosis Detection Via EBC-GM in Ventilated Patients
Brief Research Proposal: Non-Invasive Detection of Invasive Pulmonary Aspergillosis in ICU Patients Background: Invasive Pulmonary Aspergillosis (IPA) is a critical threat to patients in ICUs, especially those undergoing…
- Conditions
- Bronchoalveolar Lavage Fluid, Sensitivity and Specificity, Critical Illness, Respiration Failure
- Trial name
- NCT06333379
- Testing
- Compare the levels of Galactomannan (GM) levels in exhaled breath condensate (EBC) and BALF
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Lin Chen
Gastric Cancer
Glycans Bound to Serum Haptoglobin: a Novel Gastric Cancer Tumor Biomarker
The purpose of this study is to evaluate sensitivity and specificity of newly defined tumor biomarker with gastric cancer pts and cancer-free healthy volunteers.
- Trial name
- NCT02848066
- Testing
- Blood sample(10cc) collection
- Where
- South Korea
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
the Coagulolytic Balance, the Mortality Rate
Interest of the Balance of Pro-coagulating and Profibrinolytis Activities of the Microparticles (MP) in the Prognosis of Septic Shock
Septic shock is a clinical syndrome occurring in 10 to 20% of patients admitted in ICV. Mortality associated to septic shock varies from 30 to 50%.
- Conditions
- the Coagulolytic Balance, the Mortality Rate, the Performance Used to Evaluate the Principal Objective Are Technical Performances, Sensibility and Specificity of the Tests
- Trial name
- NCT02062970
- Testing
- blood draw
- Where
- France
- Volunteers
- 230 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
To Evaluate the Sensitivity and Specificity of a Test Kit in Hong Kong
The Diagnostic Accuracy of Using Faecal-DNA Test (COLOSAFE) for Colorectal Cancer Screening
To evaluate the sensitivity and specificity of the test kit "COLOSAFE' in Hong Kong
- Trial name
- NCT04030637
- Where
- Hong Kong
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
CAR T-Cell Therapy
An Evaluation Trial About Anti-claudin18.2 the Specificity of Chimeric Antigen Receptor T Cells in the Advanced Gastric / Esophagogastric Junction Adenocarcinoma and Pancreatic Cancer Subjects
An Evaluation Trial About Anti-claudin18.2 the Specificity of Chimeric Antigen Receptor T Cells in the Advanced Gastric / Esophagogastric Junction Adenocarcinoma and Pancreatic Cancer Subjects.
- Trial name
- NCT05277987
- Testing
- HEC-016(0.5×10^6 CAR-T Cells), HEC-016(0.5×10^6.5 CAR-T Cells), HEC-016(0.5×10^7 CAR-T Cells)
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Shenzhen Fifth People's Hospital
Lichen Planus
Cellular and Molecular Biomarkers in Patients With Lichen Planus
Lichen planus (LP) is a chronic inflammatory disease of unknown aetiology, affecting the skin and mucous membranes, characterised by a CD8+ cytotoxic T-cell infiltrate, associated with epithelial cell death and disruption of the…
- Trial name
- HELP (NCT06451744)
- Testing
- Blood samples collection, Skin or mucous membrane brushing, Skin or mucous membrane biopsy
- Where
- 6 sites in France
- Volunteers
- 70 people
- Sponsor
- Institut Pasteur
Dyspepsia
UBT as a Diagnostic Tool for HP Prevalance
The prevalence of H. pylori infection in Pakistan is unknown and investigators want to assess it in dyspeptic patients utilizing UBT.
- Trial name
- NCT02570776
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- National Institute of Liver & GI Diseases, Pakistan
Gastrointestinal Cancer
Sensitivity and Specificity of NGS in Detecting bMSI in Patients With Gastric, Duodenal and Small Intestinal Cancer
To study the sensitivity and specificity of NGS in detecting Microsatellite State in blood and to evaluate its potential application in gastrointestinal cancer.
- Trial name
- NCT03915171
- Testing
- Next generation sequencing
- Where
- China
- Volunteers
- 50 people
- Sponsor
- China Medical University, China
Intervertebral Disc Displacement, Intervertebral Disc Degeneration
Lumbar Disc Space Height in Young Disc Herniation and Degeneration Patients
As low back pain (LBP) imposes a heavy socioeconomic burden, early detection of pathologic intervertebral disc change in young adults holds high clinical relevance as a common structural cause of LBP.
- Conditions
- Intervertebral Disc Displacement, Intervertebral Disc Degeneration, Low Back Pain
- Trial name
- NCT02351206
- Testing
- x-ray, MRI
- Volunteers
- 389 people, healthy volunteers welcome
- Sponsor
- Jaseng Hospital of Korean Medicine
Ovarian Cancer
EARLY Study: Evaluating the Specificity and Feasibility of the EARLY Biomarker Panel for Ovarian Cancer Detection
The overall aim of the EARLY study is to systematically evaluate the impact of blood collection protocols, storage temperatures, transport conditions, and time to processing on the stability of extracellular vesicle (EV)…
- Trial name
- NCT07491081
- Testing
- Intervention 1, Intervention 2
- Where
- 2 sites in Australia
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Queensland Centre for Gynaecological Cancer
Focal Dystonia
Neurophysiology of Task-Specificity of Focal Hand Dystonia
This study will examine how the brain coordinates movement in patients with focal hand dystonia. Patients with dystonia have muscle spasms that cause uncontrolled twisting and repetitive movement or abnormal postures.
- Trial name
- NCT00309010
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cystic Fibrosis-related Diabetes
Cystic Fibrosis Related Diabetes Screening.
Cystic fibrosis-related diabetes is a late cystic fibrosis (CF) associated comorbidity whose prevalence is increasing sharply lifelong. Guidelines for glucose metabolism (GM) monitoring relies on oral glucose tolerance test .
- Trial name
- D2M (NCT02723968)
- Testing
- glucose solution at a dose of 1.75 g/kg (up to a maximum of 75 g) for the OGTT and glucose solution at a dose of 0.5 g/kg (up to a maximum of 35 g) was injected in 2.5-3 min for the IGTT, HGPIV diagnosis test, HOMAR-IR diagnosis test
- Volunteers
- 29 people
- Sponsor
- Hospices Civils de Lyon
Abnormal Vitreous Humor Morphology, Abnormal Choroid Morphology
Accuracy of the Red Reflex Test in the Pediatric Population
This study is designed to investigate the sensitivity and specificity of the Red Reflex Test (RRT), with and without dilation, for early detection of ocular abnormalities in children and newborns.
- Conditions
- Abnormal Vitreous Humor Morphology, Abnormal Choroid Morphology, Optic Nerve Diseases, Retinal Disease
- Trial name
- NCT04125043
- Testing
- Direct ophthalmoscope
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute