Clinical trials: Specificity
Coccidioidomycosis
A Multi-center Study of Spherule-Derived Coccidioidin
Adult volunteers were skin tested with 1.27 ug spherule-derived coccidioidin. The skin test antigen was evaluated in three different populations of adult volunteers to determine the safety and efficacy of the product in the…
- Trial name
- NCT00690092
- Testing
- Spherule-derived coccidioidin
- Where
- 4 sites in United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Nielsen BioSciences, Inc.
Wearing Off Effect, Parkinson Disease
the Prevalence of "Wearing-off" in Patients With Parkinson's Disease in Shanghai
The study would be designed as a multi-center cross-sectional investigation on the prevalence of Wearing-off in Parkinson's patients in Shanghai as well as related influencing factors.
- Trial name
- shapd-woq (NCT03792204)
- Testing
- Wearing-off 9 questionnaire
- Where
- China
- Volunteers
- 1,480 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Training Group, Control Group
Efficacy of an Autobiographical Memory Specificity and Savoring Training for the Reduction of Depressive Symptomatology
The effect of autobiographical memory specificity and savoring training on memory specificity, positive affect regulation, well-being and depression symptomatology
- Trial name
- PESCAR (NCT05220618)
- Testing
- Autobiographical Memory Specificity and Savoring Training: PESCAR
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- University of Valencia
Siewert Type I-II Adenocarcinoma of the Esophagus
Siewert Type I-II: CT, PET-CT, EUS Sensitivity/Specificity for the Assessment of Lymph Node Metastases
In Siewert type I/II EAC, sensitivity/specificity of CT, PET-CT, EUS for assessment of N descriptor in defined groups of lymph nodes were investigated.
- Trial name
- ADECC2-2017 (NCT03529968)
- Testing
- esophagectomy
- Where
- Italy
- Volunteers
- 101 people
- Sponsor
- University of Bologna
Neuromuscular Blockade
Mindray Neuromuscular Transmission Transducer
A new NMT module from Mindray (Mindray Co. Shenzhen, People's Republic of China.) claims to measure 3 directional accelerography.
- Trial name
- NMT1 (NCT02892045)
- Testing
- MMG
- Where
- 2 sites in Bosnia and Herzegovina, China
- Volunteers
- 48 people
- Sponsor
- Suez Canal University
Respiratory Viruses
Detecting Respiratory Viruses in Upper and Lower Respiratory Tract Samples
Background: Bronchoalveolar lavage (BAL) is a procedure where a tube is passed through the mouth or nose into the lungs. Fluid is squirted through the tube into a part of the lung and then collected for examination.
- Trial name
- NCT01597089
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Delirium
Comparison of Delirium Evaluation Tools Effectiveness in Intensive Care Patients
This study compares the efficacy of scoring models used in delirium prediction in patients applying to intensive care unit. The diagnosis of delirium is based on the Intensive Care Delirium Screening Checklist (ICDSC).
- Trial name
- NCT03934645
- Testing
- Delirium prediction model for ICU patients, version 1, Delirium prediction model for ICU patients, version 2, Early prediction model for delirium in ICU patients
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Trakya University
Cystic Fibrosis-related Diabetes
Cystic Fibrosis Related Diabetes Screening.
Cystic fibrosis-related diabetes is a late cystic fibrosis (CF) associated comorbidity whose prevalence is increasing sharply lifelong. Guidelines for glucose metabolism (GM) monitoring relies on oral glucose tolerance test .
- Trial name
- D2M (NCT02723968)
- Testing
- glucose solution at a dose of 1.75 g/kg (up to a maximum of 75 g) for the OGTT and glucose solution at a dose of 0.5 g/kg (up to a maximum of 35 g) was injected in 2.5-3 min for the IGTT, HGPIV diagnosis test, HOMAR-IR diagnosis test
- Volunteers
- 29 people
- Sponsor
- Hospices Civils de Lyon
Obesity
Clinic-based Nasopharyngoesophagogastroscopy Following Bariatric Surgery
This study aims to determine that this new technology, nasopharyngoendoscopy, is just as effective in diagnosing problems as the current gold standard.
- Trial name
- EGScan (NCT01602991)
- Testing
- clinic-based nasopharyngoendoscopy, Standard Endoscopy
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Dennis Hong MD
Hepatitis B, Hepatitis B Infection
Diagnostic Sensitivity and Specificity of iStatis HBsAg Test at the Point-Of-Care Site Settings
A prospective cross-sectional study in which surgically non-invasive sample-taking is done only for the purpose of testing the samples on iStatis HBsAg Test at the point of care.
- Trial name
- NCT06368479
- Testing
- iStatis HBsAg Test
- Where
- South Africa
- Volunteers
- 1,400 people
- Sponsor
- bioLytical Laboratories
Meridians
The Moxibustion-Induced Thermal Transport Effect Between The Heart And Lung Meridians
Although some important progresses were made in the field of the meridian research, no breakthroughs have been achieved. Besides,there are some problems in meridian researches.
- Trial name
- NCT05330403
- Testing
- Moxibustion
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Zhejiang Chinese Medical University
Syphilis, Syphilis Infection
Retrospective Study of iStatis Syphilis Ab Test (POC)
The purpose of this retrospective clinical trial is to establish the clinical performance of the iStatis Syphilis AbTest. The data will be used to demonstrate the product is safe and effective for its intended use.
- Trial name
- NCT06367621
- Testing
- iStatis Syphilis Antibody Test
- Where
- South Africa
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- bioLytical Laboratories
Sarcoma, Soft Tissue Tumors
Magnetic Resonance Imaging or Ultrasound in Soft Tissue Tumors (MUSTT)
Adult soft tissue sarcomas (STS) are rare tumours with an estimated incidence averaging 5/100 000/year in Europe. The prognosis of soft tissue sarcomas is dominated by local recurrence and distant metastasis.
- Conditions
- Sarcoma, Soft Tissue Tumors, Ultrasound, Magnetic Resonance Imaging
- Trial name
- MUSTT (NCT02834585)
- Testing
- Ultrasound
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- University of Genova
Carbon Monoxide Poisoning
Role of Pulse Co-oximetry for Detecting Carbon Monoxide Poisoning in the Prehospital Emergency Medical Service Setting
The RAD-57 pulse CO-oximeter is a lightweight device allowing non-invasive measurement of blood carboxyhemoglobin. Previous studies comparing RAD-57 measurements (SpCO) to standard laboratory blood gas analysis (COHb) have…
- Trial name
- CO-OX (NCT02860455)
- Testing
- RAD57 measurement (SpCO), CO-oximeter
- Where
- France
- Volunteers
- 176 people
- Sponsor
- University Hospital, Montpellier
Right to Left Shunt, Patent Foramen Ovale
Right to Left Cardiac Shunt Detection
The purpose of this study is to evaluate the sensitivity and specificity of the Cardiox Flow Detection System (FDS) in identifying an intracardiac right-to-left shunt (RLS) compared to the results of transesophageal…
- Conditions
- Right to Left Shunt, Patent Foramen Ovale, Atrial Septal Defect
- Trial name
- PFO Detection (NCT01773252)
- Testing
- Flow Detection System
- Where
- 8 sites in United States
- Volunteers
- 141 people
- Sponsor
- Cardiox Corporation
Immuno-modulation, Immuno-suppression
Analysis of the Specificity and Persistence of Nasal Immune Responses to Respiratory Viral Antigens in Immunocompromised and Healthy Cohorts
The goal of this observational study is to characterize nasal mucosal immunity to respiratory viruses, such as SARS-CoV-2, in immunocompromised individuals and healthy volunteers.
- Conditions
- Immuno-modulation, Immuno-suppression, Immunocompromised Patients, Healthy Subjects
- Trial name
- NCT07295535
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Tuberculosis Infection
Equivalence Study of Specificity of PPD
Determine if investigational products and reference standard produce similar responses.
- Trial name
- 03 (NCT01798095)
- Testing
- Aplisol@ PPD material, Reference Standard
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- JHP Pharmaceuticals LLC
Invasive Cancer, Ductal Carcinoma in Situ
The Mammography and Ultrasonography STudy for Breast Cancer Screening Effectiveness
Mammography screening has limited performance in young women or women with dense breasts although it is the only proven method for breast cancer screening that reduces the mortality.
- Trial name
- MUST-BE (NCT02909426)
- Testing
- Ultrasonography, Digital mammography
- Where
- South Korea
- Volunteers
- 11,880 people, healthy volunteers welcome
- Sponsor
- Soonchunhyang University Hospital
Breast Cancer
A Pilot Study on Use of Liquid Crystal Contact Thermography to Detect Early Breast Cancer
The study was a multicentre, observational, cross-sectional, open and monitored trial involving 274 females who were subject to an examination using liquid crystal contact thermography device as a complementary tool to standard…
- Trial name
- NCT03858738
- Testing
- Thermographic breast examination performed by Braster device
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Braster S.A.
Acute Kidney Injury, Acute Renal Injury
Renal and Cardiac Risk Factors of AKI After Liver Transplantation
Background: Liver transplantation (LT) is an extensive operation with various factors contributing to the development of acute kidney injury in the perioperative period.
- Conditions
- Acute Kidney Injury, Acute Renal Injury, Liver Transplant; Complications
- Trial name
- NCT05666232
- Testing
- renal resistive index and myocardial performance index
- Volunteers
- 105 people
- Sponsor
- Mansoura University