Clinical trials: Spectrum
Autism
Meeting the Needs of Young Hispanic Autistic Children
Purpose of the Study: The goal of this clinical trial is to find out if a technique called the "mutual gaze procedure" used in a Culturally and Linguistically Responsive adaptation of Pathways Early Intervention (CLR-Pathways) is…
- Trial name
- NCT06733584
- Testing
- Culturally and Linguistically Responsive Pathways Parent-Mediated Intervention without Mutual Gaze, Culturally and Linguistically Responsive Pathways Parent-Mediated Intervention
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- The University of Texas at Dallas
Autism Spectrum Disorder, Autism
Mitochondrial Dysfunction in Autism Spectrum Disorder
Researchers at Arkansas Children's Hospital Research Institute are conducting a study about mitochondrial function in children. The study involves up to 5 visits to Arkansas Children's Hospital with fasting blood draws…
- Conditions
- Autism Spectrum Disorder, Autism, Mitochondrial Disease, Developmental Delay
- Trial name
- Mito (NCT02000284)
- Where
- United States
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Schizophrenia
Involuntary Memories Investigation in Schizophrenia
Patients with schizophrenia suffer from autobiographical memory disorders. Patients have difficulty to remember vividly personal past events when they are specifically asked for.
- Trial name
- NCT03209778
- Testing
- Patients with Schizophrenia
- Where
- France
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Psychosis
Effectiveness of the Combination of Water Aerobics and Metacognitive Training
The objective of this study is to assess the efficacy of a combined intervention of water aerobics and Metacognitive Training (MCT), compared to each intervention separately, in people with psychosis.
- Trial name
- NCT05455593
- Testing
- Water aerobics, Metacognitive Training (MCT), Combined intervention
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Fundació Sant Joan de Déu
Autism
Autism - Children's Improvisational Music Therapy Evaluation
The goal of this clinical trial is to evaluate the effectiveness of individual sessions of improvisational music therapy for autistic children aged 7 - 11.
- Trial name
- CHIME (NCT06016621)
- Testing
- Improvisational Music Therapy
- Where
- 2 sites in United Kingdom
- Volunteers
- 240 people
- Sponsor
- Prof Simon Baron-Cohen
Schizophrenia
Treatment Response in Schizophrenia: Bridging Imaging and Postmortem Studies
The overarching goal is to identify imaging markers that will predict treatment response, and to confirm or validate these biomarkers using anatomical studies of postmortem tissue.
- Trial name
- NCT00937716
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Acceptance and Commitment Therapy, Psychotic Disorders
Acceptance and Commitment Therapy (ACT) in Early Psychosis Patients
This study is to examine the effect of Acceptance and Commitment Therapy applied to patients in early psychosis patients on psychotic symptoms and functionality levels.
- Conditions
- Acceptance and Commitment Therapy, Psychotic Disorders, Psychiatric Nursing
- Trial name
- NCT05210816
- Testing
- Acceptance and Commitment Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Schizoaffective Disorder, Bipolar Type, Bipolar Disorder
Psychoneuromentalism Disorder: A Medical Condition That Affects People With Psychological Impairments From Health Issues
Psychoneuromentalism Disorder is a disorder arising in the mind; that is related to the mental and emotional state of a person. It is the science of mental life. The body has a natural design to heal itself.
- Conditions
- Schizoaffective Disorder, Bipolar Type, Bipolar Disorder, ADHD - Combined Type, Dissociative Disorder
- Trial name
- PNMD (NCT06235177)
- Testing
- Decompartmentalization Framework, Liquid Herbal TInctures, Mental Imagery
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Essence of Integrative Health and Medicine Practice
Developmental Disability, Intellectual Disability
Validation of Optical Genome Mapping for the Identification of Constitutional Genomic Variants in a Postnatal Cohort
The purpose of this research use only (RUO) study is to detect genomic structural variants (SVs) in human DNA by Optical Genome Mapping (OGM) using the Bionano Genomics Saphyr system.
- Conditions
- Developmental Disability, Intellectual Disability, Autism Spectrum Disorder, Congenital Anomaly
- Trial name
- NCT05295277
- Testing
- Standard of care genetic testing group
- Where
- 8 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Bionano Genomics
Schizophrenia, Schizoaffective Disorder
Cognitive Behavioral Social Skills Training in Early Onset Psychosis
Cognitive-behavioral therapy (CBT) and social skills training (SST) are recommended psychological interventions to improve symptomatology and functional recovery in psychosis.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Psychosis NOS
- Trial name
- NCT03261557
- Testing
- CBT + SST, Psychoeducation, habits and healthy lifestyle
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Autistic Disorder
e-Unstuck:Interactive e-Learning Software for Parents to Support Executive Functioning and Behavior Regulation in Children With Autism Spectrum Disorder
The goal of this project is to develop and test e-Unstuck, an e-learning intervention that (1) provides advanced training to parents of children with Autism Spectrum Disorder without Intellectual Disability (ASDwoID) on how to…
- Trial name
- e-Unstuck (NCT02708069)
- Testing
- e-Unstuck, Unstuck and On Target
- Where
- 2 sites in United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- 3-C Institute for Social Development
Major Depressive Disorder, Anxiety
Brexpiprazole (OPC-34712) as an Adjunctive Treatment in Adults With Major Depressive Disorder and Anxiety Symptoms
The purpose of this study is to investigate the efficacy and safety of flexibly dosed adjunctive brexpiprazole treatment in subjects with major depressive disorder and anxiety symptoms, who are experiencing an inadequate…
- Trial name
- NCT02013531
- Testing
- Brexpiprazole
- Where
- 21 sites in United States
- Volunteers
- 37 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Hearing Loss, Sensorineural
The EarLens Contact Hearing Device (CHD) Spectrum Study
The EarLens System is an assistive hearing device that is intended to provide amplification for the treatment of patients with sensorineural hearing impairment.
- Trial name
- Spectrum (NCT02470494)
- Testing
- Sound amplification provided via the EarLens CHD
- Where
- 8 sites in United States
- Volunteers
- 46 people
- Sponsor
- EarLens Corporation
Autism Spectrum Disorder
Postural Control During Walking and Standing Among Children With Autism Spectrum Disorder
Lately, many researchers have found that Children with autism spectrum disorder (ASD) are most likely to have gross motor deficiencies such as lack of coordination in gait and balance.
- Trial name
- PCASD (NCT02584972)
- Testing
- no intervention required
- Where
- 2 sites in Israel
- Volunteers
- 40 people
- Sponsor
- Soroka University Medical Center
Autism Spectrum Disorder, Parents
Virtual Reality Experiences as Tools to Support Mental Health in Parents of Children With Autism
Mindfulness is a technique that involves the intentional and non-judgmental regulation of attention to the present moment, with curiosity, openness, and acceptance, as per its definition.
- Trial name
- Mind-VR (NCT05852795)
- Testing
- Virtual Reality-mediated Mindfulness-Based Interventions, Virtual Reality-mediated Mindfulness-Based Interventions without audio guided experience
- Where
- Italy
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Treatment Compliance, Social Media
TTM-Based Social Media Psychoeducation for Psychosis
This doctoral research investigates the effect of a Transtheoretical Model (TTM)-based psychoeducation program delivered via social media on treatment adherence in individuals diagnosed with psychosis.
- Conditions
- Treatment Compliance, Social Media, Psychotic Disorders
- Trial name
- TAPS (NCT07080827)
- Testing
- TTM-Based Online Psychoeducation Program, Standard Face-to-Face Psychoeducation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Dissociative Disorders, Schizophrenia
Prevalence of Dissociative Disorders in Children
Schizophrenia beginning before 18 years is a clinical entity not well known because of its low incidence and difficulties in the clinical diagnosis.
- Trial name
- NCT01512641
- Testing
- Primary stage, Secondary stage
- Where
- 4 sites in France
- Volunteers
- 301 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Schizophrenia, Schizoaffecitve Disorder
Digital Therapeutics for Social Cognitive Function in Schizophrenia Spectrum Disorder
The purpose of this study is to evaluate the safety and preliminary effectiveness of a smartphone-based digital therapeutic application (AffectUs) for improving social cognition, particularly emotion processing and social cue…
- Trial name
- NCT07755605
- Testing
- Digital therapeutic (AffectUs), Psychoeducational materials
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Samsung Medical Center
Psychosis
Mechanisms of Cognitive Change
This study will determine whether targeted cognitive training, a low-cost and low-risk commercial cognitive remediation therapy, directly impacts therapeutic targets as well as secondary outcomes in college undergraduates.
- Trial name
- CTCS (NCT04103775)
- Testing
- Cognitive Remediation, Active Control
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Smoking Cessation, Nicotine Addiction
Circuitry-Guided Smoking Cessation in Schizophrenia
In a double-blinded, randomized, parallel controlled design, patients with schizophrenia spectrum disorder will be exposed to active or sham repetitive transcranial magentic stimulation (TMS) which was guided by functional…
- Conditions
- Smoking Cessation, Nicotine Addiction, Schizophrenia
- Trial name
- NCT03281629
- Testing
- Active TMS stimulation
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Maryland, Baltimore