Clinical trials: Spectrum
Autism
Oxcarbazepine Versus Placebo in Childhood Autism
The proposed study is designed to assess the effectiveness of treatment with Oxcarbazepine vs. placebo in childhood/adolescent autism.
- Trial name
- NCT00467753
- Testing
- Oxcarbazepine
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Autistic Disorder, Enuresis
Investigation of Teacher-Mediated Toilet Training Using a Manualized Moisture Alarm Intervention
The purpose of this pilot study is to compare an innovative toilet training strategy with a standard behavioral intervention in children with autism spectrum disorder (ASD), as implemented by teachers in the school setting.
- Trial name
- NCT02369445
- Testing
- Moisture Pager Intervention for Toilet Training, Standard of Care
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Schizophrenia, Chronic Psychiatric Disorder
Mental Healthcare in Older Adults With Schizophrenia
As in the general population, there is a gradual and steady increase in life expectancy of patients with schizophrenia. But this increase is at a smaller scale, with a rate of premature death that is still 2 to 3 times higher…
- Trial name
- CSA (NCT02884739)
- Testing
- Data collection
- Where
- France
- Volunteers
- 685 people
- Sponsor
- CHU de Reims
Autism Spectrum Disorder
Intestinal Microbiota, Tryptophan and Autism
Autism Spectrum Disorder refers to complex neuro-developmental disorders that affect social communication and behavioral adaptation.
- Trial name
- MTA (NCT03751930)
- Testing
- Samples
- Where
- 2 sites in France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Autism
Testing a Mobile App to Improve Toothbrushing Skills and Habits in Teens With Autism
The goal of this proposed trial will modify an existing toothbrushing app for teens with autism and compare toothbrushing outcomes with a control app.
- Trial name
- NCT06208722
- Testing
- Testing a Mobile App to Improve Toothbrushing Skills and Habits in Teens With Autism
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- University of Washington
Schizophrenia
Receptor Occupancy of ITI-007 Using Positron Emission Tomography (PET) in Patients With Stable Schizophrenia
The purpose of this study is to determine the relationship between ITI-007 dose, plasma levels and brain receptor occupancy in patients with stable schizophrenia.
- Trial name
- NCT02288845
- Testing
- ITI-007
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Intra-Cellular Therapies, Inc.
Mood Disorders, Schizophrenia
Assessing the Effect of Compensatory Cognitive Intervention Among People With Severe Mental Illness
The aim of this study is to assess the efficacy of a short term compensatory cognitive group intervention - the Compensatory Cognitive Training (CCT) among people with severe mental illnesses, receiving ambulatory treatment
- Conditions
- Mood Disorders, Schizophrenia, Schizoaffective Disorder
- Trial name
- NCT04551027
- Testing
- compensatory cognitive treatment
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Shalvata Mental Health Center
Schizophrenia, Memory Disorders
The Effects of Atomoxetine on Cognition and Brain Function Based on Catechol-O-methyltransferase(COMT) Genotype
This study will evaluate whether Atomoxetine improves cognition in healthy volunteers as well as patients with schizophrenia. Atomoxetine is a drug that has been Food and Drug Administration (FDA) approved for Attention Deficit…
- Conditions
- Schizophrenia, Memory Disorders, Cognition Disorders
- Trial name
- Atomoxetine (NCT00548327)
- Testing
- Atomoxetine, Functional magnetic resonance imaging, Neuropsychological Testing
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Autism, Autism Spectrum Disorder
Online Evaluation of the Diagnostic Accuracy of BlinkLab's Digital Assessments for Autism
This observational study aims to evaluate how patterns of behavioral and sensorimotor responses measured using the BlinkLab Dx1 smartphone application relate to autism diagnoses in children ages 2 to 11.
- Conditions
- Autism, Autism Spectrum Disorder, Autism Spectrum Disorder (ASD), Neurodevelopmental Conditions
- Trial name
- NCT07590973
- Testing
- BlinkLab Dx1, Retrospective Neurodevelopmental Diagnostic Assessment
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Blinklab Limited
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Autistic Disorder
Early Intervention With Fluoxetine in Autism
This study is a pilot study to evaluate the feasibility and safety of conducting a year long, double-blind, placebo-controlled trial of fluoxetine in pre-school children to enhance developmental processes in core areas impacted…
- Trial name
- NCT00183339
- Testing
- Fluoxetine
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- University of North Carolina, Chapel Hill
Schizophrenia, Drug Abuse
A Pilot, Proof-of-concept Cohort Study of the Prevalence of Comorbid Mental Illness and Substance Abuse
The prevalence estimates for specific mental disorders and illicit drugs have been separately reported in U.S. government surveys.
- Conditions
- Schizophrenia, Drug Abuse, Anxiety Disorder, Bipolar Disorder
- Trial name
- NCT02476877
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Advanced Clinical Laboratory Solutions, Inc.
Autism Spectrum Disorder
Comparative Effectiveness of EIBI and Adaptive ABA for Children With Autism
Approximately 15,000 children with autism spectrum disorder (ASD) in military families currently receive applied behavior analysis (ABA) interventions through TRICARE insurance.
- Trial name
- ISOLDE (NCT04078061)
- Testing
- MABA, EIBI
- Where
- 5 sites in United States
- Volunteers
- 56 people
- Sponsor
- University of Rochester
Schizophrenia, Transcranial Magnetic Stimulation
Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment for Schizophrenia Patients With Auditory Hallucinations
To investigate the treatment effect of continuous transcranial magnetic stimulation on schizophrenia patients with auditory hallucinations, and the underlying neural mechanism by functional MRI
- Conditions
- Schizophrenia, Transcranial Magnetic Stimulation, Functional Magnetic Resonance Imaging
- Trial name
- NCT02863094
- Testing
- transcranial magnetic stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Anhui Medical University
Schizophrenia and Schizophrenia Spectrum Psychosis
Modafinil as an Adjunctive on Cognitive Functioning in Patients With Schizophrenia
Patients suffering from schizophrenia and schizophrenia spectrum psychosis frequently experience cognitive impairments. Such deficits may affect memory, attention and executive function processes.
- Trial name
- NCT00314639
- Testing
- modafinil
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Laval University
Autism Spectrum Disorder
AUT-MENU: Improving Meal Experience of Subjects With Autism Spectrum Disorder
The main goal of this multi-center interventional study is to improve the meal experience of children and adolescents with autism spectrum disorder trough the development of menus for collective catering targeted to their…
- Trial name
- NCT06266377
- Testing
- Administration of menus of collective catering adapted to the sensory and nutritional needs of subjects with Autism Spectrum Disorder, Nutrition education course aimed at caregivers of individuals with Autism Spectrum Disorder
- Where
- 3 sites in Italy
- Volunteers
- 200 people
- Sponsor
- University of Pavia
Psychosis
Psychosis TMS Study
The main goal of this study is to investigate the neural mechanisms of working memory function in patients with early psychosis using Transcranial Magnetic Stimulation (TMS) in conjunction with functional MRI.
- Trial name
- NCT05857137
- Testing
- Active TMS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
High Risk Group of Schizophrenia
Early Identification and Predictive Parsing for High Risk Group of Schizophrenia
An accurate identification of individuals at ultra-high risk (UHR) based on psychometric tools to prospectively identify psychosis as early as possible is required for indicated preventive intervention.
- Trial name
- NCT05042739
- Testing
- CAARMS;SIPS; BSABS;
- Where
- China
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Wuhan Mental Health Centre
Schizophrenia
Double Blind, Placebo-controlled Study of Raloxifene for Negative Symptoms of Schizophrenia in Postmenopausal Women
Primary objective: To assess the efficacy of adding raloxifene as an adjunct to antipsychotic treatment to improve negative symptoms of schizophrenia in postmenopausal women.
- Trial name
- NCT01041092
- Testing
- raloxifene
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Fundació Sant Joan de Déu
Autism Spectrum Disorders
Martial Arts Therapy in Autism Spectrum Disorders
The purpose of the present study was to determine whether teaching Karate techniques training leads to reduction in communication deficit of children with autism spectrum disorders.
- Trial name
- NCT02493699
- Testing
- physical exercise- based intervention (Karate techniques training)
- Volunteers
- 30 people
- Sponsor
- University of Isfahan