Clinical trials: Speech Disorder
Mild Cognitive Impairment, Primary Progressive Aphasia
Home-based tDCS in Frontotemporal Dementia or Alzheimer's Disease
The primary objective of this research is to evaluate the effects of non-invasive brain stimulation and computerized cognitive training on executive functioning in individuals with Primary Progressive Aphasia (PPA), mild…
- Conditions
- Mild Cognitive Impairment, Primary Progressive Aphasia, Dementia
- Trial name
- NCT05978804
- Testing
- Computerized Cognitive Training, Active tDCS (tDCS) on DLPFC
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Johns Hopkins University
Aphasia
Rhythm-based Intervention in Aphasia
Every year, approximately 100,000 people are diagnosed with aphasia-a language disorder leading to substantial difficulties in their daily communication.
- Trial name
- NCT04581564
- Testing
- Rhythm-based speech therapy app (i.e., Speech Hero), Non-rhythm based (singing) application (conventional speech therapy)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- The University of Texas at Dallas
Primary Progressive Aphasia
HDtDCS in Logopenic Variant PPA: Effects on Language and Neural Mechanisms
This study aims to evaluate the effectiveness of a therapy called High-Definition Transcranial Direct Current Stimulation (HD-tDCS) for the treatment of the language deficits experienced by people with a type of Primary…
- Trial name
- NCT03805659
- Testing
- HD-tDCS
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Medical College of Wisconsin
Parenting Practices, Self Efficacy
Evaluation Study of Talk Parenting Skills
After development of the prototype Bedtime Routine module of the Talk Parenting program, the investigators will evaluate its feasibility and initial efficacy in a within-subjects pre-post design study.
- Conditions
- Parenting Practices, Self Efficacy, Stress, Child Behavior
- Trial name
- NCT04633434
- Testing
- The Talk Parenting Skill for Alexa
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Aphasia
TMS in Aphasia Recovery
Stroke often causes substantial problems in speaking or understanding speech. Treatments for these problems are currently very limited.
- Trial name
- NCT04777214
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Pennsylvania
Stuttering, Stuttering, Childhood
Speech Processing in Stuttering
This research is being done to better understand stuttering, specifically how people who stutter may process and/or produce speech.
- Conditions
- Stuttering, Stuttering, Childhood, Stuttering, Adult
- Trial name
- NCT04929184
- Testing
- Speech and non-speech tasks
- Where
- 2 sites in United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Childhood Apraxia of Speech
Treating Childhood Apraxia of Speech
The study will test two modifications to speech therapy for 40 school-age children with childhood apraxia of speech to determine how to improve treatment outcomes.
- Trial name
- NCT03238677
- Testing
- Speech Motor Chaining without Biofeedback, Biofeedback, Distributed Practice
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Syracuse University
Social Anxiety Disorder, Performance Anxiety
Acute Anxiolytic Effects of Riluzole on Subjects With Social Anxiety Disorder
The goal of the current proposal is to examine if sublingual riluzole can reduce anxiety in people with social anxiety disorder during a public speaking task.
- Trial name
- NCT03017508
- Testing
- BHV-0223
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Yale University
Larynx Cancer, Laryngectomy; Status
Phonatory Movement of the Pharyngoesophageal Mucosa in Laryngectomy Patients
The treatment of advanced laryngeal cancer involves the removal of the entire larynx. After removal of the larynx, the pharyngoesophageal segment (PES) is created by reconstructing the soft tissue of the pharynx and oesophagus…
- Trial name
- NCT05561920
- Testing
- High-speed video endoscopy (HSV), Acoustic voice analysis, Quality of life questionnaire
- Where
- Croatia
- Volunteers
- 55 people
- Sponsor
- Osijek University Hospital
Aphasia, Stroke
Brain Biomarkers of Response to Treatment for Apraxia of Speech
The study will use MRI brain imaging to identify brain changes associated in stroke patients after they receive speech-language treatment for their speech difficulties.
- Trial name
- SPT (NCT02046941)
- Testing
- Speech Production Treatment
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- VA Office of Research and Development
Primary Progressive Aphasia
Treating Primary Progressive Aphasia (PPA) Using tDCS
This is a double-blind, sham-controlled, crossover study in which subjects with the non-fluent/agrammatic and semantic variants of primary progressive aphasia (naPPA and svPPA, respectively) will undergo language testing and…
- Trial name
- NCT04566731
- Testing
- Transcranial Direct Current Stimulation (tDCS), Modified Contraint-Induced Language Therapy (mCILT)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Pennsylvania
Hearing Loss, Sensorineural
PC-Based Rehabilitation of Auditory Function
Many older subjects experience difficulty in understanding speech in noisy environments. Part of this problem is related to changes that occur in the ear with age and compromise the hearing of high-pitched sounds.
- Trial name
- CINT (NCT00724347)
- Testing
- Consonant Identification Training
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Hearing Loss
Safety and Effectiveness of the MED-EL Electric-Acoustic System
The purpose of this investigation is to demonstrate the safety and effectiveness of the MED-EL Electric-Acoustic System (EAS), a medical device that combines the use of a cochlear implant with an external electric-acoustic…
- Trial name
- EAS (NCT00747435)
- Testing
- Electric Acoustic System
- Where
- 14 sites in United States
- Volunteers
- 73 people
- Sponsor
- Med-El Corporation
Aphasia, Primary Progressive Aphasia
CB3 Pilot (Communication Bridge: A Person-centered Internet-based Intervention for Individuals With Primary Progressive Aphasia)
This study will evaluate evidence-based treatments for adults with mild Primary Progressive Aphasia (PPA). The aim of the study is to help identify efficacious communication and quality of life interventions for those with PPA…
- Conditions
- Aphasia, Primary Progressive Aphasia, Dementia, Communication
- Trial name
- CB3 Pilot (NCT05697380)
- Testing
- Communication Bridge™
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Chicago
Speech Sound Disorder
Auditory-Perceptual Training Via Telepractice
The objective of this study is to measure the effects of online perceptual training on perception and production in children with RSE who exhibit atypical perception relative to norms from our lab-based pilot data.
- Trial name
- NCT04858035
- Testing
- Perceptual training, Production training
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Montclair State University
Selective Mutism
What Treatment Works for Children With Selective Mutism?
The purpose of this pilot study is to explore the outcome of a manual based treatment for children with Selective Mutism
- Trial name
- NCT00554749
- Testing
- Interventions at home, in the kindergarten/school
- Where
- Norway
- Volunteers
- 7 people
- Sponsor
- Regionsenter for barn og unges psykiske helse
Hearing Impairment, Sensorineural
CP1150 Sound Processor Speech Perception Compared With the Next Generation of Signal Processing Technology
This clinical study aims to investigate speech performance in quiet with an OTE Sound Processor with modified firmware compared with the commercially available CP1150.
- Trial name
- NCT05286385
- Testing
- CP1150 Sound Processor, CP1150 NF, CP1150 + FF
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- Cochlear
Hearing Loss, Sensorineural
Evaluation of an Open-source Speech-processing Platform
Determining acceptability and usability of a wearable open-source speech processing platform (Master Hearing Aid) developed for hearing-aid research
- Trial name
- EOSP (NCT03686046)
- Testing
- Exploratory use
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Apraxia Speech
Transcranial Magnetic Stimulation (TMS) for Primary Progressive Apraxia of Speech (PPAOS)
The purpose of this study is to assess the influence of transcranial magnetic stimulation (TMS) on speech performance in individuals with primary progressive apraxia of speech.
- Trial name
- NCT03028324
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Miami
Social Anxiety Disorder, Selective Mutism
Treatment of Social Anxiety Disorder and Selective Mutism
This study is to assess the efficacy of a brief, 11-week, manualized Taming Sneaky Fears for Social Anxiety Disorder (SAD) and/or Selective Mutism (SM) child and parent group Cognitive Behavioural Therapy (CBT) treatment…
- Trial name
- SAD&SMTRMT (NCT02554929)
- Testing
- Taming Sneaky Fears, Parent Psycho-education and Child Socialization
- Where
- Canada
- Volunteers
- 93 people
- Sponsor
- The Hospital for Sick Children