Clinical trials: Speech Impairment
Strategy Training
Strategy Training for People With Aphasia After Stroke
One-third to one-half of acute strokes result in newly acquired cognitive impairments. Approximately 30 to 40% of people in the acute phase of stroke also sustain communication impairments.
- Trial name
- NCT03593876
- Testing
- Strategy Training
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Pittsburgh
Stroke, Aphasia
Effects of Transcranial Direct Current Stimulation (tDCS) on Language
This study will investigate the effects of mild electrical stimulation in conjunction with speech therapy for people with post-stroke aphasia to enhance language recovery.
- Trial name
- NCT04166513
- Testing
- Targeted Transcranial Direct Current Stimulation, Active Control Transcranial Direct Current Stimulation, Phonologic-Focused Speech Therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Medical College of Wisconsin
Stroke, Aphasia
Evaluating Anodal tDCS Preceding Aphasia Therapy
The purpose of this study is to determine if non-invasive brain stimulation (transcranial direct current stimulation) delivered prior to language therapy will improve word-finding in individuals with aphasia who are 6 months or…
- Trial name
- NCT02249819
- Testing
- transcranial direct current stimulation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Northwell Health
Aphasia, Apraxia of Speech
Treatments of Acquired Apraxia of Speech
This study was designed to examine the effects of speech therapy on ability to produce speech sounds in persons with acquired apraxia of speech.
- Conditions
- Aphasia, Apraxia of Speech, Stroke
- Trial name
- Apraxia (NCT01483807)
- Testing
- Sound Production Treatment - Blocked, Sound Production Treatment - Random
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Aging, Mild Cognitive Impairment
Internet-based Conversational Engagement Clinical Trial
The study aims to randomize 320 (160 Caucasian, 160 African American) socially isolated adults 75+ years old (50:50 split between those with normal cognition and mild cognitive impairment (MCI)) recruited from the community to…
- Trial name
- I-CONECT (NCT02871921)
- Testing
- Conversational Engagement
- Where
- 2 sites in United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Primary Progressive Aphasia, MCI
tDCS Intervention in Primary Progressive Aphasia
Primary progressive aphasia (PPA) is a neurodegenerative disease that affects first and foremost language abilities. Mild cognitive impairment (MCI) is slowly progressive decline in a single domain of cognition (e.g.
- Conditions
- Primary Progressive Aphasia, MCI, FTD
- Trial name
- NCT02606422
- Testing
- Active HD-tDCS plus Speech-Language Therapy
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Aphasia
Transcranial Direct Stimulation (tDCS) and Behavioral Intervention in Aphasia
We hypothesize patients who have difficulty with word recall (naming pictures) due to a stroke will experience greater benefit in word recall after receiving a combination of transcranial direct current stimulation (tDCS) and…
- Trial name
- NCT02226796
- Testing
- Transcranial direct current stimulation
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Minnesota
Childhood-Onset Fluency Disorder (Stuttering)
Effects of Ecopipam or Placebo in Adults With Stuttering (Speak Freely)
This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group, Phase 2 exploratory study in adult subjects with childhood onset fluency disorder.
- Trial name
- NCT04492956
- Testing
- Ecopipam
- Where
- 9 sites in United States
- Volunteers
- 68 people
- Sponsor
- Emalex Biosciences Inc.
Hearing Loss
Clinical Applications for Time-Compressed Speech Tests
The purpose of this study is to determine the effects of age-related cognitive changes on hearing aid benefit based on hearing aid compression time constants.
- Trial name
- NCT00371839
- Testing
- Audiological Evaluation
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Primary Progressive Aphasia
Transmagnetic Stimulation Pilot in Primary Progressive Aphasia
Frontotemporal degeneration (FTD) is a non-Alzheimer's dementia that is the 2nd most common cause of dementia in the United States.
- Trial name
- TMS in PPA (NCT05860647)
- Testing
- Intermittent theta burst stimulation
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- HealthPartners Institute
Aphasia, Spatial Neglect
Prism Adaptation in Left Brain Stroke
Of the 15,000 Veterans who are hospitalized for stroke each year more than half experience spatial and motor impairments and pain.
- Conditions
- Aphasia, Spatial Neglect, Stroke
- Trial name
- NCT04387162
- Testing
- Prism Adaptation Treatment
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- VA Office of Research and Development
Aphasia, Aphasia Non Fluent
Speech Entrainment for Aphasia Recovery
After a stroke, many people experience a language impairment called aphasia. One of the most debilitating types of aphasia is non-fluent aphasia.
- Conditions
- Aphasia, Aphasia Non Fluent, Stroke
- Trial name
- SpARc (NCT04364854)
- Testing
- SET (Speech Entrainment Therapy) 3 weeks, SET (Speech Entrainment Therapy) 4.5 weeks, SET (Speech Entrainment Therapy) 6 weeks
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- Medical University of South Carolina
Hearing Loss
Evaluation of Open-canal Behind-the-Ear Hearing Aids and Traditional In-the-ear Hearing Aids.
This study is being conducted to evaluate the benefits of in-the-ear vs. open-fit behind-the-ear hearing aids. We want to learn more about which patients prefer each type, so we can make better choices about which type of hearing…
- Trial name
- NCT00727909
- Testing
- Hearing Aid Treatments
- Where
- 3 sites in United States
- Volunteers
- 290 people
- Sponsor
- US Department of Veterans Affairs
Aphasia
Assessing an Animal-Assisted Treatment Program for Adults With Aphasia: The Persons With Aphasia Training Dogs Program
The lives of more than 2 million Americans are affected by aphasia, an acquired language impairment most commonly resulting from stroke that affects the ability to remember and express words.
- Trial name
- PATD (NCT04610346)
- Testing
- Persons with Aphasia Training Dogs Program
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Albert Einstein Healthcare Network
Primary Progressive Aphasia
Communication Bridge 2
This study will use a randomized controlled trial design to evaluate the effect of two evidence-based treatments for adults with mild Primary Progressive Aphasia (PPA).
- Trial name
- CB2 (NCT03371706)
- Testing
- Communication Bridge™, Evidence-Based Impairment Focused
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- University of Chicago
Apraxia of Speech, Aphasia
A Novel Treatment for Aphasia and Apraxia of Speech : Measurement of Outcomes
In order to determine if speech-language therapy has positive effect, reliable measurement tools are required to document outcomes.
- Trial name
- NCT01979159
- Testing
- Combined Aphasia and Apraxia of Speech Treatment (CAAST)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- VA Office of Research and Development
Aphasia, Cerebrovascular Accident
Treating Intention In Aphasia: Neuroplastic Substrates
The purpose of this study is to determine if an "intentional act" improves treatment response for patients with nonfluent aphasia. The treatment involves naming pictures and saying members of categories.
- Trial name
- NCT00567242
- Testing
- Word-finding with intention component, Word-finding with no intention component
- Where
- 3 sites in United States
- Volunteers
- 14 people
- Sponsor
- University of Florida
Primary Progressive Aphasia
Transcranial Direct Current Stimulation for Primary Progressive Aphasia
In the present sham-controlled study, the investigators examine whether tDCS could be used to enhance language abilities (e.g., picture naming) in individuals with primary progressive aphasia (PPA) primarily characterized by…
- Trial name
- NCT02928848
- Testing
- transcranial direct current stimulation
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Pennsylvania
Hoarding Disorder
Imaginal Exposure for Hoarding Disorder
The present study will test a potential new treatment strategy, imaginal exposure, for hoarding disorder. Although cognitive behavioral therapy often reduces hoarding, some people do not want to start, or cannot handle, that…
- Trial name
- NCT03734705
- Testing
- Imaginal Exposure Writing, Neutral Writing
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Stanford University
Mild Cognitive Impairment, Primary Progressive Aphasia
Home-based tDCS in Frontotemporal Dementia or Alzheimer's Disease
The primary objective of this research is to evaluate the effects of non-invasive brain stimulation and computerized cognitive training on executive functioning in individuals with Primary Progressive Aphasia (PPA), mild…
- Conditions
- Mild Cognitive Impairment, Primary Progressive Aphasia, Dementia
- Trial name
- NCT05978804
- Testing
- Computerized Cognitive Training, Active tDCS (tDCS) on DLPFC
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Johns Hopkins University