Clinical trials: Speech and Language Disorder
Language Development, Language Development Disorders
Cortical Tracking of Speech in the First Year of Life
The goal of this observational study is to investigate early neural mechanisms underlying the processing of spoken language, specifically the phenomenon of cortical tracking, and to determine whether these mechanisms can serve as…
- Conditions
- Language Development, Language Development Disorders, Infant Development, Infant Developmental Assessment
- Trial name
- NCT07531706
- Testing
- Electrophysiological recording, Behavioral Assessment
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Stuttering, Adult, Stammering
Study of the Effect of the Auditory Stimulation on Stuttering Symptoms in Patients With a Deficit of Spectral Power in the EEG Beta Frequency Band
In this study, the investigators will research the efficacy of a novel auditory neuro modulating technology that leverages euphonic music tracks with broad-spectrum binaural beats to induce selective EEG spectral power changes.
- Trial name
- ZOV (NCT05339906)
- Testing
- ZOV.ai digital therapy candidate
- Where
- Ukraine
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Oles Honchar Dnipro National University
Stammering
Modifying Unconscious Tongue Movements in Adults With Developmental Stammer.
This is a pilot randomised controlled trial investigating whether using modification of saccadic eye movements can control lateral unconscious tongue positioning and enhance fluency in adults with a confirmed developmental…
- Trial name
- NCT04310436
- Testing
- Modifying saccades by looking down to naval., Modifying saccades by looking in air.
- Where
- Ireland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Institute of Technology, Sligo
Parkinson Disease
Intelligibility Assessment for Parkinson's Disease
The investigators aim at testing the efficacy of an app to measure sentence intelligibility in noise in speakers with Parkinson's disease and in healthy controls.
- Trial name
- NCT04829006
- Testing
- Understand Me For Life
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Long Island University
Speech and Language Disorder, Speech Therapy
Providing Speech Therapy Awareness in Private Schools
There has been limited research in the area of speech and language therapy awareness in Pakistan. The study aims to assess the efficacy of providing speech therapy awareness in private schools through a pre-post model.
- Conditions
- Speech and Language Disorder, Speech Therapy, Speech Delay, Swallowing Disorder
- Trial name
- NCT04505696
- Testing
- Speech-Language Pathology Presentation
- Where
- Pakistan
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Obstructive Sleep Apnea, Breathing, Sleep-Disordered
Cheeks Appearance as a Novel Predictor of Obstructive Sleep Apnea The CASA Score Study
Cheeks appearance is a screening tool developed based on cheeks observation to identify volume, flaccidity or both to predict people with probable obstructive sleep apnea.
- Conditions
- Obstructive Sleep Apnea, Breathing, Sleep-Disordered, Muscle Weakness, Muscle Disorder
- Trial name
- CASA (NCT04980586)
- Testing
- CASA score protocol to Non-obstructive sleep apnea Group, CASA score protocol to Mild obstructive sleep apnea Group, CASA score protocol to Moderate obstructive sleep apnea Group
- Where
- Brazil
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Brain Mapping, Deafness
Areas of Brain Responsible for Understanding American Sign Language
The human brain is made up of two halves called hemispheres. Each half of the brain is responsible for processing different kinds of information.
- Conditions
- Brain Mapping, Deafness, Healthy
- Trial name
- NCT00001782
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Dementia, Alzheimer Disease
The Swedish BioFINDER 2 Study
The Swedish BioFINDER 2 study is a new study that will launch in 2017 and extends the previous cohorts of BioFINDER 1 study (www.biofinder.se). BioFINDER 1 is used e.g.
- Conditions
- Dementia, Alzheimer Disease, Parkinson Disease, Lewy Body Disease
- Trial name
- BioFINDER2 (NCT03174938)
- Testing
- Flutemetamol F18 Injection, [18F]-RO6958948, Elecsys (Roche) Abeta42, Ttau and Ptau
- Where
- 2 sites in Sweden
- Volunteers
- 2,950 people, healthy volunteers welcome
- Sponsor
- Skane University Hospital
Stroke, Aphasia
Choir Singing in Aphasia Rehabilitation
This study evaluates the verbal, cognitive, emotional, and neural efficacy of a choir singing intervention in chronic aphasic patients and their caregivers.
- Trial name
- NCT03501797
- Testing
- Singing-based rehabilitation, Standard care
- Where
- 2 sites in Finland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Aphasia, Rehabilitation
Acupuncture + Neuromodulation for Post-Stroke Aphasia
The aim of this clinical trial is to assess the therapeutic efficacy of acupuncture combined with neuromodulation techniques for the treatment of post-stroke aphasia and to explore the brain mechanisms involved.
- Trial name
- NCT06493747
- Testing
- Combined Low- and High-Frequency rTMS Intervention, Combined High- and Low-Frequency rTMS Intervention, rTMS
- Where
- China
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Shanghai Yueyang Integrated Medicine Hospital
Parkinson Disease
Supplementary Motor Area is a Potential Target for Speech Disturbance in Parkinson Disease
Speech disturbance is common in patients with Parkinson disease. Pharmacotherapy improves motor symptoms but has inconsistent effects on speech disturbance in PD patients.
- Trial name
- NCT05478057
- Testing
- "MAGSTIM" Repetitive transcranial magnetic stimulator (rTMS) system
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Developmental Language Disorder, Adults Without Language Disorder
Category Learning Retention in Adults With and Without Developmental Language Disorder
Approximately 7% of the population experiences developmental language disorder (DLD), a language disorder with unclear causes. DLD affects communication beyond adolescence and poses challenges for education and career advancement…
- Trial name
- Time2Learn (NCT05901493)
- Testing
- Perceptual category training
- Where
- 2 sites in United States
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Aphasia, Acquired, Stroke
Neurocognitive Mechanisms of Sentence Production Impairment in Aphasia
The proposed research is relevant to public health because stroke is a leading cause of long-term disability among older adults and communication impairments resulting from stroke have a significant negative impact on quality of…
- Conditions
- Aphasia, Acquired, Stroke, Healthy Aging
- Trial name
- sentence (NCT06405594)
- Testing
- Language Condition
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Social Phobia
Treatment of Childhood Social Phobia
This 4-year study will compare the long-term effectiveness of behavioral treatment, fluoxetine (Prozac®), and placebo for treatment of social phobia in children and adolescents.
- Trial name
- NCT00043537
- Testing
- Social Effectiveness Therapy for Children (SET-C), Fluoxetine
- Where
- United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Speech Intelligibility, Speech Disorders
Validation of the Turkish Translation of the London Speech Evaluation Scale
Purpose of the study is the validation and cultual adaptation of the Turkish translation of the London Speech Evaluation Scale (LSE-T), so that it would be used as an assessment tool for Turkish head and neck cancer patients.
- Conditions
- Speech Intelligibility, Speech Disorders, Head and Neck Cancer, Speech Dysfunction
- Trial name
- NCT04690166
- Testing
- The speech records related to the reading document
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Language Impairment, Hearing Loss
Characterization of Auditory Processing Involved in the Encoding of Speech Sounds
The ability to encode the speech signal is determined by ascending and descending auditory processing. Difficulties in processing these speech signals are well described at the behavioral level in a specific language disorder.
- Trial name
- PRODIPRICIDE (NCT02574299)
- Testing
- E-learning, Hearing aids fitting
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Cerebrovascular Accident, Aphasia
Dopaminergic Enhancement of Learning and Memory in Aphasia
The purpose of this study is to determine whether levodopa, in combination with a high frequency language training, is effective in boosting naming performance in patients with aphasia.
- Trial name
- NCT00102869
- Testing
- levodopa
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Ischemic Stroke
Percutaneous Recanalization in Ischemic Stroke Management (PRIISM): A Feasibility Clinical Study
The primary study objective is to assess the feasibility of using the MindFrame System to safely and effectively restore blood flow in a thrombotic neurovascular occlusion in patients experiencing an ischemic stroke.
- Trial name
- PRIISM (NCT00810095)
- Testing
- MindFrame System
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- MindFrame, Inc.
Primary Progressive Aphasia, Dementia
Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia
Difficulties with speech and language are the first and most notable symptoms of primary progressive aphasia (PPA). While there is evidence that demonstrates positive effects of speech-language treatment for individuals with PPA…
- Conditions
- Primary Progressive Aphasia, Dementia, Dementia, Frontotemporal, Alzheimer Disease
- Trial name
- NCT05741853
- Testing
- Video-Implemented Script Training for Aphasia (VISTA), Lexical Retrieval Training (LRT)
- Where
- 3 sites in United States, Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stephanie Grasso
Autistic Disorder
Social Skills in Children With ASD and Process Drama
This is a one-group, pre-post feasibility study of an intensive, interdisciplinary (theatre, Occupational Therapy (OT), and Speech Language Pathology (SLP)) intervention targeted at social skill development in children, aged 3-4.
- Trial name
- NCT02850666
- Testing
- Interdisciplinary process drama
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Utah