Clinical trials: Sperm Selection, open to volunteers
Infertility
PICSI Impact on Euploidy in Assisted Reproduction
Hyaluronic acid (HA) is a major component of the cumulus complex surrounding oocytes. Intracytoplasmic sperm injection (ICSI) involves injection of a selected sperm into the oocyte.
- Trial name
- NCT06602687
- Testing
- PICSI
- Where
- Ireland
- Volunteers
- 142 people
- Sponsor
- Merrion Fertility Clinic
Infertility, IVF
Sex Selection of Human Spermatozoa
This study aims to demonstrate a reliable method of selecting gender specific sperm. X-bearing spermatozoa and Y-bearing spermatozoa will be identified from the density gradient layers.
- Trial name
- NCT05500573
- Testing
- Sperm Sorting
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Male Fertility, Testicular
Use of the SiDTM v2.0 Algorithm to Assist Embiyologists in Sperm Selection During ICSI Procedures
Infertility is defined as a failure of a couple to achieve a pregnancy after 12 or more months of unprotected intercourse. Males are found to be solely responsible for 20-30% of infertility cases but contribute to 50% of cases…
- Conditions
- Male Fertility, Testicular, Sperm Parameters in Fertile and Infertile Men, Sperm Selection
- Trial name
- SID_3 (NCT07163754)
- Testing
- Automated Sperm Selection, Conventional Sperm Selection
- Volunteers
- 100 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Infertility (IVF Patients), Male Fertility
Functional Development and Clinical Validation of a Diagnostic Tool Based on Artificial Intelligence for the Assessment of Sperm Quality and the Selection of the Optimal In Vitro Fertilisation (IVF) Treatment
Infertility is a growing global health problem affecting millions of couples worldwide, with male infertility accounting for approximately half of all cases.
- Conditions
- Infertility (IVF Patients), Male Fertility, Sperm Selection
- Trial name
- NCT07185984
- Testing
- Sperm sellection, DIAGNOSIS TOOL
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Infertile Patient Undergoing ICSI Procedure
Advanced Sperm Selection in ICSI: A Comparative Study of PICSI and ZyMot
our study explores the effectiveness of two advanced sperm selection techniques-PICSI and the ZyMot microfluidic device-in improving outcomes of Intracytoplasmic Sperm Injection (ICSI).
- Trial name
- NCT07240779
- Testing
- picsi dish
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sunrise Fertility Center
Infertility, Fertility Disorders
Live Birth Rate After Sperm Selection Using ZyMōt Multi (850µL) Device for Intra Uterine Insemination
This single centre interventional pilot randomized control study intends to compare two methods of sperm preparation for couples referred for Intra Uterine Insemination (IUI) procedure.
- Trial name
- FERTINSEM (NCT06144268)
- Testing
- ZyMōt Multi (850µL), Density Gradient Centrifugation
- Where
- Belgium
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Infertility (IVF Patients), Oocyte Competence
The EPIC Study: Exploring Paternal Age and the Influence on Blastocyst Culture
This study aims to assess the effect of age of the male partner and the reproductive ability of sperm prepared via sperm selection devices (Zymot) compared to routine embryologist selected sperm after density gradient…
- Conditions
- Infertility (IVF Patients), Oocyte Competence, Sperm DNA Fragmentation, Paternal Age
- Trial name
- EPIC (NCT06629766)
- Testing
- Microfluidic sperm separation device, Density grade centrifugation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Reproductive Medicine Associates of New Jersey
Infertility, Male, Sperm Count, Low
Study of the ZyMōt Sperm Selection Method and Its Effect on Embryo Ploidy.
It has been described that 11% of men with semen values within the normal range established by the World Health Organization (WHO) have sperm DNA fragmentation.
- Trial name
- ZYMOT2 (NCT06384794)
- Testing
- Sperm capacitation through the ZyMōt®Sperm Separation Device®, Swim-up
- Where
- 2 sites in Spain
- Volunteers
- 80 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Infertility, Male Infertility
The Efficiency of a New Sperm-Wash Device for Intrauterine Insemination in Couples With Infertility
This study evaluates the effectiveness of a novel sperm-wash device designed to improve outcomes in intrauterine insemination (IUI) for couples with infertility.
- Trial name
- IUI (NCT06956287)
- Testing
- LensHooke CA0, Density Gradient Centrifugation (DGC)
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Chung Shan Medical University