Clinical trials: Sphenopalatine Ganglion Nerve Block
Chronic Migraine, Cluster Headache
Intra-arterial Sphenopalatine Ganglion Block for Patients With Refractory Headache
The purpose of this study is to evaluate the safety and efficacy of intra-arterial (IA) delivery of Dexamethasone and Ketorolac into the arteries supplying the sphenopalatine ganglion (SPG) - a collection of neurons that plays an…
- Conditions
- Chronic Migraine, Cluster Headache, Trigeminal Neuralgia
- Trial name
- NCT04353505
- Testing
- Ketorolac, Dexamethasone
- Where
- United States
- Sponsor
- Weill Medical College of Cornell University
Post-Dural Puncture Headache
Trans-nasal Sphenopalatine Ganglion Block Versus Ultrasound-guided Bilateral Greater and Lesser Occipital Nerve Block for Management of Post-Dural Puncture Headache.
Post-Dural Puncture Headache (PDPH) is a complication associated with spinal anesthesia. While conventional treatments are available, the Epidural Blood Patch (EBP) is considered the gold standard.
- Trial name
- TNSPGB /GALONB (NCT06705244)
- Testing
- Trans-nasal sphenopalatine nerve block, Greater and lesser occipital nerve block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Postdural Puncture Headache, Cerebrospinal Fluid Leak
Sphenopalatine Ganglion Nerve Block for Postdural Puncture Headache in Obstetrics
The SNOB study is a prospective, randomized, double-blind, placebo-controlled, cross-over pragmatic trial that has been designed in accordance with the CONSORT guidelines.
- Conditions
- Postdural Puncture Headache, Cerebrospinal Fluid Leak, Spinal; Puncture, Complications, Headache
- Trial name
- SNoB (NCT03181464)
- Testing
- Lidocaine 4%
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Hadassah Medical Organization
Craniotomy Surgery
Sphenopalatine Ganglion Block Combined With Either Scalp Nerve Block or Local Wound Infiltration for Postoperative Analgesia in Adult Patients Undergoing Craniotomy: A Randomized Controlled Trial
The use of multimodal regional analgesia (scalp block, local scalp infiltration, and sphenopalatine ganglion block) for postoperative pain management after craniotomy
- Trial name
- NCT07886034
- Testing
- Group (c): control group patients will receive general anesthesia., Group (SS): Sphenopalatine Ganglion Block with either Scalp Nerve Block, Group (SL): patients will receive Sphenopalatine Ganglion Block with local wound infiltration
- Volunteers
- 54 people
- Sponsor
- Zagazig University
Migraine
Comparison of Occipital Nerve and Sphenopalatine Ganglion Blockade
Migraine is a chronic disorder that causes disability. Episodic migraine can be managed by prophylactic medical treatment or interventional pain procedures.
- Trial name
- NCT06243874
- Testing
- greater occipital nerve block, transnasal sphenopalatine ganglion block
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ankara University
Cluster Headache
Botox Injection in Treatment of Cluster Headache
Cluster headache is an intense and powerful, one-sided headache accompanied by involuntary symptoms such as red eye, droopy eyelids, flow of tears, small pupils and one-sided facial sweating.
- Trial name
- NCT02019017
- Testing
- Botulinum Toxin Type A 25 IU, Botulinum Toxin Type A 50 IU
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Norwegian University of Science and Technology
Surgery, Anesthesia, Local
Block of the Sphenopalatine Nerve Ganglion for Postoperative Analgesia
Transsphenoidal surgery is considered safe and effective and is currently the procedure of choice for the removal of intrasellar lesions.
- Conditions
- Surgery, Anesthesia, Local, Postoperative Pain
- Trial name
- NCT04339231
- Testing
- sphenopalatine ganglion block
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Postoperative Analgesia
Infraorbital-Infratrochlear Block vs Sphenopalatine Ganglion Block for Postoperative Analgesia in Septorhinoplasty.
This prospective, randomized, double-blind clinical trial aims to compare the postoperative analgesic efficacy and recovery outcomes of infraorbital-infratrochlear nerve block and transnasal sphenopalatine ganglion block in…
- Trial name
- NCT07345039
- Testing
- Infraorbital-Infratrochlear Nerve Block, Transnasal Sphenopalatine Ganglion Block
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Trigeminal Neuralgia
Sphenopalatine Ganglion Block with Tx360 for Trigeminal Neuralgia
The aim of this study was to investigate the effect of sphenopalatine ganglion (SPG) block bilaterally through a nasal device called Tx360 by delivering 0.3cc of lidocaine 2% for pain relief in patients with Trigeminal Neuralgia…
- Trial name
- NCT06663410
- Testing
- SPG block with the use of the Tx360 device
- Where
- Greece
- Volunteers
- 15 people
- Sponsor
- Aretaieio Hospital
Sphenopalatine Ganglion Nerve Block
Sphenopalatine Ganglion Block Study
The goal of this clinical trial is to compare the administration and dosage of bupivacaine for sphenopalatine ganglion (SPG) nerve block.
- Trial name
- NCT05707754
- Testing
- Bupivacaine, angiocatheter
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Cluster Headache
Botulinum Toxin Type A Blockade of the Sphenopalatine Ganglion in Treatment-refractory Chronic Cluster Headache
Cluster headache is a primary headache condition characterized by clusters of one-sided, high-intensity pain attacks. The headache may be episodic or chronic. Treatment options are limited and their effects unsatisfactory.
- Trial name
- BASIC (NCT03944876)
- Testing
- Botulinum toxin type A
- Where
- 5 sites in Germany, Italy and 3 more
- Volunteers
- 112 people
- Sponsor
- Norwegian University of Science and Technology
Transformed Migraine, Chronic Daily Headache
Sphenopalatine Ganglion Nerve Block vs. Elavil for Treatment of Transformed Migraines
This study will compare a local anesthetic technique that has been used to treat subjects suffering from transformed migraines (chronic migraines) versus medical management with traditional antidepressant Amitriptyline / Elavil.
- Trial name
- NCT02090998
- Testing
- SPG Block with 5% Lidocaine gel, Amitriptyline
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Rutgers, The State University of New Jersey
Sphenopalatine Ganglion Nerve Block, Transnasal Endoscopic Pitutary Surgery
Sphenopalatine Block vs Dexmedetomidine Infusion in Trans Nasal Endoscopic Pituitary Surgery
Improving pain and surgical field by using sphenopalatine ganglion block and dexmedetomidine in trans-nasal endoscopic pituitary surgery.
- Trial name
- NCT06639659
- Testing
- Sphenopalatine Ganglion Block, Dexmedetomidine, General Anesthesia (control group)
- Where
- Egypt
- Volunteers
- 69 people
- Sponsor
- Zagazig University
Post-Dural Puncture Headache
Bilateral Sphenopalatine Ganglion Block With or Without Bilateral Greater Occipital Nerve Block for Treatment of Obstetric Post-Dural Puncture Headache
Post-dural puncture headache is a common complication, following neuraxial techniques. The obstetric population is particularly prone to PDPH. Therefore, treatment of PDPH is a key issue in obstetric anesthesia.
- Trial name
- NCT04844229
- Testing
- Bilateral transnasal sphenopalatine ganglion block., Bilateral ultrasound guided greater occipital nerve block.
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Migraine Disorders
Botulinum Toxin Type A Blockade of the Sphenopalatine Ganglion in Treatment-refractory Chronic Migraine
This is a clinical trial to assess the efficacy of botox treatment of the sphenopalatine ganglion as an add-on treatment in drug resistant migraine.
- Trial name
- MiBlock (NCT04069897)
- Testing
- Botulinum toxin type A
- Where
- 4 sites in Norway
- Volunteers
- 170 people
- Sponsor
- St. Olavs Hospital
Quality of Recovery (QoR-15), Sphenopalatine Ganglion Block
Effect of Bilateral SPG and Infraorbital Nerve Blocks on Recovery After Septorhinoplasty
This prospective, randomized, double-blind controlled study aims to compare the effects of bilateral sphenopalatine ganglion and infraorbital nerve blocks on postoperative recovery quality in patients undergoing elective…
- Conditions
- Quality of Recovery (QoR-15), Sphenopalatine Ganglion Block, Infraorbital Nerve Block
- Trial name
- NCT06929429
- Testing
- Bilateral Sphenopalatine Ganglion Block, Bilateral Infraorbital Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people
- Sponsor
- Konya City Hospital
Nerve Block
Sphenopalatine Ganglion Block to Treat Shoulder Pain After Laparoscopic Surgery
This is a prospective double blinded randomized pilot trial to evaluate the efficacy of phenopalatine ganglion block (SPGB) block to manage shoulder tip pain (STP) after laparoscopic surgery.
- Trial name
- NCT04101019
- Testing
- Lidocaine, Saline Solution
- Where
- Israel
- Volunteers
- 76 people
- Sponsor
- Rabin Medical Center
Headache
Sphenopalatine Ganglion Block Versus Occiptal Nerve Block in Treatment of Post Dural Puncture Headache
Postdural puncture headache (PDPH) is a common complication associated with neuraxial anesthesia and diagnostic lumbar puncture (LP).
- Trial name
- PDPH (NCT03156049)
- Testing
- Sphenopalatine block, Greater occipital nerve block
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Assiut University
Pituitary, Pain, Postoperative
Postop Pain Management in Pituitary Tumour Patients
To assess the benefit of using an additional nerve block during minimally invasive pituitary surgery, to improve pain management after surgery.
- Trial name
- POPPY (NCT06353529)
- Testing
- Bupivacaine-Epinephrine 0.5%-1:200,000 Injectable Solution
- Where
- Canada
- Volunteers
- 108 people
- Sponsor
- Hamilton Health Sciences Corporation
Migraine in Children, Sphenopalatine Neuralgia
SPG Block for Acute Pediatric Migraine
This is a randomized double blind trial comparing an intranasal sphenopalatine block with 2% lidocaine to intravenous (0.15 mg/kg, max 10mg) prochlorperazine in patients greater than 10 years of age presenting to a pediatric…
- Conditions
- Migraine in Children, Sphenopalatine Neuralgia, Migraine in Adolescence
- Trial name
- NCT03984045
- Testing
- Lidocaine topical, Prochlorperazine Injection
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Newark Beth Israel Medical Center