Clinical trials: Spider Phobia
Phobias
fMRI Study Examining Effects of D-cycloserine in Specific Phobia
The research team hopes to use brain imaging and mental testing to learn more about specific phobias and the treatment of phobia.
- Trial name
- NCT00591825
- Testing
- D-cycloserine
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Specific Phobias
tDCS-Augmented Exposure Therapy for Pathological Fear
This double-blind randomized controlled clinical trial aims to test whether transcranial direct current stimulation (tDCS) can be used to modulate fear extinction learning during exposure therapy for pathological fear, including…
- Trial name
- NCT03095482
- Testing
- Transcranial Direct Current Stimulation (tDCS), In vivo exposure therapy
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Fear of Spiders
Neural Mechanisms of Imaginal and in Vivo Exposure
Imaginal exposure is a widely used and effective psychological treatment technique. Recent research suggests that neural activations and emotional responses during imaginal exposure are similar to those elicited during in vivo…
- Trial name
- NCT05193383
- Testing
- Imaginal exposure, Exposure, Approach-avoidance conflict
- Where
- Sweden
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Phobic Disorders
The Role of Treatment Expectation in Exposure Training With Spider Fearful Participants
This study evaluates the role of treatment success expectation in spider fearful individuals on the actual treatment success. Half of participants will have positive treatment success expectations, while the other half will have…
- Trial name
- NCT03012035
- Testing
- positive treatment expectations, neutral treatment expectations
- Where
- Switzerland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Specific Phobia
Extinction Generalization in Exposure Therapy
Patients with anxiety disorders oftentimes express fear responses to more than only one fear-inducing object. The principal aim of this study is to examine whether the beneficial effects of exposure on fear reduction in spider…
- Trial name
- NCT03031002
- Testing
- Exposure treatment for spider fear
- Volunteers
- 77 people
- Sponsor
- Ruhr University of Bochum
One Week Follow-up Assessment, Six Weeks Follow-up Assessment
The Effect of Time on Generalization of Exposure-based Benefit
Participants will receive a pre-assessment and an exposure with a control spider. This control spider will be presented again at post-training assessments.
- Conditions
- One Week Follow-up Assessment, Six Weeks Follow-up Assessment, Three Months Follow-up Assessment
- Trial name
- NCT06255821
- Testing
- Exposure
- Where
- Germany
- Volunteers
- 59 people
- Sponsor
- Ruhr University of Bochum
Spider Fear, Arachnophobia
Optimizing Exposure Using Occasional Aversive Imagery in Spider Fearful Individuals
The effectiveness of an optimized extinction training is investigated in spider-fearful individuals. Participants will undergo a one-session standardized extinction training, either with or without occasional metal imagination of…
- Trial name
- NCT05424250
- Testing
- occasional aversive imagination, Exposure
- Where
- Germany
- Volunteers
- 67 people
- Sponsor
- Philipps University Marburg
Posttraumatic Stress Disorder, Anxiety Disorder
Pilot Study of Pharmaceutical and Behavioral Interventions to Treat Anxiety Disorders
The aim of this project is to create fear conditioning paradigm within which the relative strengths of various novel pharmacological and behavioral interventions can be tested.
- Trial name
- NCT01631682
- Testing
- Propranolol, Reactivation, Mifepristone
- Where
- United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Specific Phobia, Arachnophobia
Use of Safety Behaviors in Exposure Therapy for Arachnophobia
This study examines the impact of safety behaviors (i.e., unnecessary protective actions) on outcomes of exposure therapy for spider phobia.
- Conditions
- Specific Phobia, Arachnophobia, Spider Phobia
- Trial name
- NCT04470882
- Testing
- Exposure with faded safety behaviors, Exposure without safety behaviors, Exposure with unfaded safety behaviors
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- University of Nevada, Reno
Fear of Spiders, Fear of Heights
Generalized Fear Extinction to Untreated Fear Stimuli in Specific Phobias After Exposure
This study investigates whether a one-session exposure treatment for spider-related stimuli can lead to a generalization of extinguished fear to height-related stimuli in individuals with comorbid fear of spiders and fear of…
- Trial name
- NCT03907345
- Testing
- Exposure
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Ruhr University of Bochum
Spider Phobia
EMDR in Spider Phobia: Work Mechanisms and Treatment Outcome
The goal of this study is to increase the efficiency of exposure in virtual reality (VR). Based on the EMDR research the investigators would like to show that the implementation of eye movements during the VR exposure results in…
- Trial name
- NCT02973919
- Testing
- Eye Movement Desensitization and Reprocessing Therapy, Virtual Reality Exposure Therapy
- Volunteers
- 53 people
- Sponsor
- University of Regensburg
Spider Phobia
One-session Treatment for Spider Fears
Despite the efficacy of exposure and response prevention (ERP) for anxiety and phobias, recent theoretical research on fear extinction via inhibitory learning suggests that cognitive restructuring (CR)--the explicit challenging…
- Trial name
- NCT03410264
- Testing
- CR-EXP, EXP-CR, Stress Management
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of North Carolina, Chapel Hill
Individuals With Fear of Spiders
Neural Activations During Imaginal Exposure in Individuals Fearful of Spiders
This study explores the brain basis of imaginal exposure, a widely used psychological treatment technique. Specifically, this study uses functional magnetic resonance imaging to examine brain areas activated during imaginal…
- Trial name
- NCT03969160
- Testing
- Imaginal exposure
- Where
- 2 sites in Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Arachnophobia, Cynophobia
Telemedicine-Based Virtual Reality Clinic for the Treatment of Phobias
The purpose of this study is to assess the feasibility of conducting a randomized controlled efficacy trial comparing the delivery of exposure therapy via a telemedicine-based virtual reality clinic (Doxy.me VR) vs.
- Conditions
- Arachnophobia, Cynophobia, Ophidiophobia
- Trial name
- NCT06302868
- Testing
- Telemedicine Exposure Therapy Using Photos and Videos, Telemedicine-Based Virtual Reality Exposure Therapy
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of South Florida
Fear of Spiders
The Neural Mechanisms of Imaginal Extinction
Imaginal exposure is a widely used and effective psychological treatment technique in which patients are exposed to fearful stimuli and situations using mental imagery.
- Trial name
- NCT05168592
- Testing
- Threat conditioning, Imaginal extinction
- Where
- Sweden
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Spider Phobia
Gamification in the Treatment of Spider Phobia
Mobile applications are more and more considered when implementing programs for treating mental disorders. The study aims to reduce avoidance and fear of spiders in spider-fearful individuals by combining exposure principles with…
- Trial name
- NCT04423783
- Testing
- 7-day exposure therapy via self-developed app according to (Haberkamp et al., submitted), Therapist-guided one-session online exposure therapy according to (Öst, 1989)
- Where
- 2 sites in Germany
- Volunteers
- 90 people
- Sponsor
- Anke Haberkamp
Arachnophobia, Phobia
TMS and Exposure Therapy
Spider phobia is an exceedingly common phobia throughout the world. The current standard treatment involves exposure therapy, which consists of a series of brief exposures of an individual to the thing they fear, in this case…
- Trial name
- NCT04019054
- Testing
- Intermittent Theta Burst Stimulation (iTBS), Ventromedial Prefrontal Cortex (vmPFC), Intermittent Theta Burst Stimulation (iTBS), vertex
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of California, Los Angeles
Specific Phobia, Animal
A Randomized Controlled Efficacy Trial of a Telemedicine-based Virtual Reality Clinic for the Treatment of Phobias
The goal of this clinical trial is to learn if a telemedicine-based virtual reality clinic (Doxy.me VR) works to treat dog, spider, and snake phobias in adults.
- Trial name
- NCT07558824
- Testing
- Telemedicine-Based Virtual Reality Exposure Therapy, Telemedicine-Based Exposure Therapy Using Photos and Videos
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of South Florida
Phobia, Specific
The Impact of Sex Hormones on One-session Treatment for Spider Phobia in Women
The purpose of this study is to determine whether levels of sex hormones (including estrogen and progesterone) influence women's response to treatment for Specific Phobia of spiders.
- Trial name
- NCT02622087
- Testing
- One-Session-Treatment
- Where
- Australia
- Volunteers
- 90 people
- Sponsor
- The University of New South Wales
Acrophobia, Arachnophobia
3D Video Virtual Reality Exposure Therapy Study
This study seeks to examine a Virtual Reality Exposure Therapy (VRET) using the 3D Video Virtual Reality (VR) technology for the fear of spiders.
- Trial name
- 3D-VVRET (NCT02584387)
- Testing
- 3D Video Virtual Reality Exposure Therapy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin