Clinical trials: Spider Phobia
Specific Phobia
Effects of Stress on Exposure Therapy
This study investigates whether stress can augment exposure therapy outcome in patients with specific phobia (spider phobia).
- Trial name
- NCT03505437
- Testing
- Cold water condition, Warm water condition
- Where
- Germany
- Volunteers
- 48 people
- Sponsor
- Ruhr University of Bochum
Fear of Spiders
Efficacy of a Gamified Augmented Reality Exposure-based Application in Subjects With Fear of Spiders
Investigation of the efficacy of a gamified augmented reality exposure app in individual with fear of spiders.
- Trial name
- GARET2019 (NCT04162509)
- Testing
- AR app
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Prof. Dominique de Quervain, MD
Claustrophobia, Obsessive-Compulsive Disorder
Efficacy of Targeted Memory Reactivation for Enhancing Exposure Therapy
This study evaluates whether a scent applied during exposure therapy and during subsequent sleep will increase the durability of treatment effects for individuals with fear of spiders, contamination, and enclosed spaces.
- Conditions
- Claustrophobia, Obsessive-Compulsive Disorder, Arachnophobia
- Trial name
- NCT04663672
- Testing
- Experimental Scent, Control Scent, No-Scent Control
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- University of Texas at Austin
Specific Phobia
Enhancing Exposure Therapy for Snake and Spider Phobias
This study tests whether exposure therapy for fear of snakes or spiders is enhanced by the addition of a brief fear retrieval trial prior to treatment, and the use of compound extinction during treatment.
- Trial name
- Snake/Spider (NCT02160470)
- Testing
- Exposure Therapy with Retrieval, Exposure Therapy with Compound Extinction, Exposure Therapy with Retrieval and Compound Extinction
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Phobias Snakes, Phobias Spiders
Bringing Exposure Therapy to Real-Life Context With Augmented Reality
In this patented project, U.S. Patent No. 10,839,707, the investigators will develop an augmented reality exposure therapy method for arachnophobia, and fear of snakes, to test in the clinic.
- Trial name
- ARET (NCT03649347)
- Testing
- Augmented reality exposure therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Wayne State University
Anxiety Disorders, Arachnophobia
Optimizing Exposure Therapy With Mental Rehearsal
Treatment response rates for cognitive behavioral therapy (CBT) across anxiety disorders average approximately 50% post-treatment (Loerinc et al, 2015), evidencing significant 'return of fear', the re-emergence of a partially or…
- Trial name
- NCT03934385
- Testing
- Mental Rehearsal, Exposure
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of California, Los Angeles
Phobic Disorders
Neurophysiological Correlates of Exposition Therapy in Spider Phobia
This study aims to investigate the neurophysiological correlates of spider phobia and its treatment with CBT based Exposure Therapy.
- Trial name
- NCT03653923
- Testing
- Exposure Therapy
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Specific Phobia
Spider Phobia Opposite Action Treatment Study
This study tests the effectiveness of exposure therapy for fear of spiders as enhanced by the use of antagonistic or opposite actions during treatment.
- Trial name
- NCT02905279
- Testing
- Biofeedback Relaxation Training, Exposure Therapy, Exposure with Threat-Relevant Opposite Actions
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Anxiety, Anxiety Disorders
In Vivo Exposure vs. Videochat-Based Vicarious Exposure
After screening (including parts of the Mini-DIPS), participants will receive a pre-assessment with a baseline heartrate measurement, self-report measures and two BATs (with the treated spider and the non-treated spider).
- Trial name
- NCT07432945
- Testing
- In Vivo Exposure Training (IVET), Vicarious Exposure Training (VicET)
- Where
- Germany
- Volunteers
- 72 people
- Sponsor
- Ruhr University of Bochum
Specific Phobia
The Effects of Safety Seeking Behaviors During Exposure Therapy for Adults With Spider Phobia
Exposure-based cognitive-behavioral therapy (i.e., "exposure therapy"), which entails repeated and prolonged confrontation with feared situations/stimuli, is the most effective treatment for anxiety disorders (e.g.…
- Trial name
- NCT03233113
- Testing
- Exposure therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of North Carolina, Chapel Hill
Phobia, Specific
Virtual Reality Immersive Method for Spider (Phobia) Exposure Therapy (VIMSE)
The aim of this study is to examine the efficacy of virtual reality exposure therapy as a treatment for specific phobia (spiders).
- Trial name
- VIMSE (NCT02533310)
- Testing
- OST treatment with in-vivo spiders, VR-OST treatment with virtual spiders
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Stockholm University
Phobia, Specific
Influence of Valproic Acid on Extinction-based Therapy in Patients With Fear of Spiders.
The purpose of this study is to evaluate whether valproic acid in combination with fear memory reactivation is useful to enhance treatment stability of exposure therapy for specific phobia.
- Trial name
- VALPRO (NCT02789813)
- Testing
- Valproic Acid, Fear reactivation, No fear reactivation
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Prof. Dominique de Quervain, MD
Fear of Spiders, Acute Stress Reaction
The Effects of Propranolol and Hydrocortisone on Military-Relevant Performance Outcomes
This clinical trial aims to evaluate the nature and duration of effects of three FDA-approved medications (propranolol and hydrocortisone) on military-relevant cognitive, emotional, and motor performance following an exposure to…
- Trial name
- NCT06982183
- Testing
- Propranolol, Hydrocortisone
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Walter Reed Army Institute of Research (WRAIR)
Specific Phobia, Cognitive-behavioral Therapy
Virtual Reality Exposure in Spider Phobia
While knowledge on the neurobiological signatures of fear and anxiety disorders and, in particular, their association with treatment outcome is accumulating, clinical translation still awaits empirical proof of evidence.
- Conditions
- Specific Phobia, Cognitive-behavioral Therapy, Virtual Reality
- Trial name
- NCT03208400
- Testing
- virtual reality exposure
- Where
- 2 sites in Germany
- Volunteers
- 338 people
- Sponsor
- Julius-Maximilians University
Spider Fear, Arachnophobia
Feasibility of an Online Modeled Exposure in Spider Fearful Individuals
The effectiveness of an optimized group exposure treatment is investigated in spider-fearful individuals. Participants will undergo an optimized standardized exposure treatment.
- Trial name
- OMEX (NCT06182709)
- Testing
- online psychoeducation video + modeled exposure, live psychoeducation video + modeled exposure, group exposure
- Where
- Germany
- Volunteers
- 78 people
- Sponsor
- Philipps University Marburg