Clinical trials: Spinal
Ankylosing Spondylitis, Exercise Training
Respiratory Training in Individuals with Ankylosing Spondylitis
This study was designed to investigate and compare the effects of standard diaphragmatic breathing and physiotherapy exercises versus 360-degree expandable diaphragmatic breathing and physiotherapy exercises on respiratory…
- Conditions
- Ankylosing Spondylitis, Exercise Training, Diaphragm, Mobility
- Trial name
- NCT06490796
- Testing
- Expanded diaphragm exercise, Standard diaphragm exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Izmir University of Economics
Manual Therapies
Spinal Manipulation and Neuromuscular Performance on Amateur Cyclists
The present study aims to assess the effects of spinal manipulation therapy on neuromuscular performance.
- Trial name
- NCT03913546
- Testing
- Spinal manipulative therapy
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alcala
Anesthesia Techniques, Percutaneous Nephrolithotomy
Effects of Spinal vs General Anesthesia on Systemic Inflammation in PCNL
This observational study aims to compare the effects of spinal and general anesthesia on perioperative systemic inflammatory response in patients undergoing percutaneous nephrolithotomy (PCNL).
- Conditions
- Anesthesia Techniques, Percutaneous Nephrolithotomy, Systemic Inflammation
- Trial name
- PCNL-ANES-INF (NCT07326670)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Kyphosis, Proprioception
Investigation of the Effect of Thoracic Kyphosis Proprioception
Although the negative effect of increased thoracic kyphosis in elderly individuals has been reported in the literature, the effect of the thoracic kyphosis angle on trunk and foot proprioception in young individuals has not been…
- Conditions
- Kyphosis, Proprioception, Posture
- Trial name
- NCT06420869
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Istanbul Medipol University Hospital
Opioid Use, Spine Fusion
Does Preoperative Pain Medication Management Influence Surgical Outcomes in Spinal Fusion
In light of the current opioid epidemic, there is an urgent need to address chronic opioid use prior to surgery before it is exacerbated by postoperative surgical pain.
- Trial name
- NCT04095624
- Testing
- Spinal Fusion Preoperative Opioid Taper, Non-taper Control
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Stanford University
Amyotrophic Lateral Sclerosis
Expression Profile Study of Macrophages From Patients Affected by ALS or Other Related Motor Impairments
The aim of this project is to analyze the macrophage transcriptome and protein markers of Amyotrophic Lateral Sclerosis (ALS) patients compared to controls (non-affected individuals, patients with other motor impairments) and…
- Trial name
- Mac2ALS (NCT04816227)
- Where
- France
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Multiple Sclerosis, Neurogenic Bladder
Clinical Study of Solifenacin Succinate in Patients With Bladder Symptoms Due to Spinal Cord Injury or Multiple Sclerosis
A clinical study to evaluate the efficacy and safety of solifenacin in patients with bladder symptoms due to spinal cord injury or multiple sclerosis
- Conditions
- Multiple Sclerosis, Neurogenic Bladder, Spinal Cord Diseases
- Trial name
- SONIC (NCT00629642)
- Testing
- Solifenacin Succinate, Oxybutynin Hydrochloride
- Where
- 39 sites in Australia, Belgium and 9 more
- Volunteers
- 249 people
- Sponsor
- Astellas Pharma Inc
Degenerative Disc Disease
INFUSE® Bone Graft and MASTERGRAFT® Granules With CD HORIZON® for Posterolateral Lumbar Fusion in Patients With Degenerative Disc Disease - Pilot Study
The purpose of this pilot clinical trial is to evaluate the feasibility of using the investigational implant (INFUSE® Bone Graft and MASTERGRAFT® Granules with the CD HORIZON® Spinal System) as a method of facilitating spinal…
- Trial name
- NCT01491542
- Testing
- INFUSE® Bone Graft/MASTERGRAFT® Granules/CD HORIZON®, Autogenous Bone / CD HORIZON® Spinal System
- Volunteers
- 46 people
- Sponsor
- Medtronic Spinal and Biologics
Hepatocellular Carcinoma, Spine Metastasis
Diffusion-Weighted Magnetic Resonance Imaging
Recently, diffusion-weighted (DW) MR imaging has widened its application on various oncologic applications. Especially, it is expected the DW MRI could provide valuable information about early response evaluation after treatment…
- Trial name
- NCT02242786
- Testing
- External beam radiation therapy
- Where
- South Korea
- Volunteers
- 17 people
- Sponsor
- Samsung Medical Center
Ankylosing Spondylitis, Aerobic Exercise
The Effects of Aerobic Exercise in Patients With Ankylosing Spondylitis
The aim of our study is to investigate the effects of aerobic exercise and stretching exercises applied in high-intensity interval training protocol on disease activity, quality of life, spinal mobility and calprotectin…
- Conditions
- Ankylosing Spondylitis, Aerobic Exercise, Disease Activity
- Trial name
- NCT05968469
- Testing
- Aerobic exercises with cycling ergometry, Stretching exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Afyonkarahisar Health Sciences University
Amyotrophic Lateral Sclerosis, Movement Disorders
Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures
The goal of the study is to generate a biorepository of longitudinal biofluids-blood (plasma and serum), cerebral spinal fluid (CSF) and urine linked to genetics and longitudinal clinical information that are made available to…
- Conditions
- Amyotrophic Lateral Sclerosis, Movement Disorders, Degenerative Disorder, Motor Neuron Disease
- Trial name
- TALSLB (NCT05137665)
- Where
- 12 sites in United States, Colombia and 1 more
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Target ALS Foundation, Inc.
Laparoscopic Donor Nephrectomy, Perioperative Pain Management
Comparison of Spinal Anesthesia Adjuvant and Quadratus Lumborum Block on the Opioid Requirement and Perioperative Pain of Laparoscopic Kidney Transplant Donor
This study aims to compare the effectiveness of spinal anesthesia adjuvant and quadratus lumborum block on the opioid requirement and perioperative pain on patients undergoing laparoscopic kidney transplant donor.
- Trial name
- NCT06764667
- Testing
- Spinal anesthesia adjuvant, Quadratus Lumborum Block (QLB), General Anesthesia
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Universitas Indonesia
Hyperkyphosis
Diaphragmatic Myofascial Release for Hyperkyphotic Subjects
kyphotic subjects have respiratory disturbances due to weakening of the diaphragm, responsible for inhalation, which lead to abnormalities in respiratory mechanics and abnormal gas exchange, leading to respiratory complications.
- Trial name
- NCT06621667
- Testing
- diaphragmatic myofascial release with traditional physical therapy exercises for hyperkyphosis, traditional physical therapy exercises for hyperkyphosis
- Volunteers
- 42 people
- Sponsor
- Cairo University
Lumbar Spinal Stenosis
Effectiveness and Safety of Korean Medicine for Lumbar Stenosis Patients With Sciatica
A prospective study investigating the effectiveness and safety in lumbar stenosis patients receiving integrative Korean medicine treatment at 3 locations of Jaseng Hospital of Korean Medicine through assessment of pain…
- Trial name
- NCT02975011
- Testing
- Herbal medicine, Chuna manipulation, Bee venom pharmacopuncture
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Jaseng Medical Foundation
Sacroiliac Joint Dysfunction
Spinal Manipulation and Dry Needling Versus Conventional Physical Therapy in Patients With Sacroiliac Dysfunction
The purpose of the research project is to compare the effectiveness of non-thrust mobilization and exercise versus thrust manipulation and dry needling in patients with sacroiliac dysfunction.
- Trial name
- NCT02373644
- Testing
- HVLA Thrust Manipulation and DN, Conventional Physical Therapy
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Alabama Physical Therapy & Acupuncture
Degenerative Disc Disease, Degenerative Scoliosis
Clinical Outcome Measure at Stryker Spine
This is a multicenter, prospective, retrospective, Post Market Clinical Follow-up (PMCF) study in subjects who have undergone or will undergo surgery utilizing one or more Stryker devices according to Stryker cleared Instructions…
- Trial name
- COMPASS (NCT06226272)
- Testing
- Spinal Fusion, Spinal Deformities Correction
- Where
- 7 sites in United States
- Volunteers
- 5,222 people
- Sponsor
- VB Spine, LLC
Infectious; Spondylitis
Prolonged Bed Rest Versus Early Raising in Vertebral Osteomyelitis
Infectious vertebral osteomyelitis are infectious diseases of the vertebral bone, intervertebral disc and/ or adjacent tissue. Most of cases are due to hematogenous dissemination of pathogen but direct inoculation is an aetiology…
- Trial name
- SPONDYL'UP (NCT04735081)
- Volunteers
- 200 people
- Sponsor
- Central Hospital, Nancy, France
Ankylosing Spondylitis, Osteoporosis
Treatment With Alendronate in Patients With Ankylosing Spondylitis (AS)
This prospective study will assess the effects of treatment with alendronate in osteoporotic patients with ankylosing spondylitis.
- Trial name
- NCT01104987
- Testing
- alendronate
- Where
- Sweden
- Volunteers
- 16 people
- Sponsor
- Göteborg University
Scoliosis, Scoliosis Idiopathic
Investigation of the Effects of Exercise and Kinesiological Taping on Spinal Deformities and Serum Markers in Individuals With Scoliosis
The aim of this study is to investigate the effects of Schroth exercises and kinesiological taping on spinal deformities and serum markers in young adults with scoliosis.
- Conditions
- Scoliosis, Scoliosis Idiopathic, Musculoskeletal Deformity
- Trial name
- NCT06341465
- Testing
- Just Exercise, Exercise, Taping
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Amyotrophic Lateral Sclerosis (ALS)
A Follow up Study to Protocol 101/2 - Continued Treatment by IPL344 IV
This is a prospective, open-label, follow up study to protocol 101/2 - continued treatment by IPL344 IV administered once a day in up to 15 participants with ALS.
- Trial name
- NCT03755167
- Testing
- IPL344
- Where
- 2 sites in Israel
- Volunteers
- 15 people
- Sponsor
- Immunity Pharma Ltd.
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