Clinical trials: Spinal
Stiff-Person Syndrome
Efficacy and Mechanism of Action of SCIg in Patients With Stiff Person Syndrome (SPS)
This is a pilot, proof-of concept investigator-initiated trial planned for 22 patients with the diagnosis of Stiff Person Syndrome (SPS).
- Trial name
- NCT03829826
- Testing
- HyQvia
- Volunteers
- 22 people
- Sponsor
- Thomas Jefferson University
Cerebral Palsy, Spastic
Influence of the Spinal Manipulation on Muscle Spasticity and Manual Dexterity in Cerebral Palsy.
The aim of the study is to evaluate a short term influence of the Spinal Manipulation (SM) on the wrist muscles spasticity and manual dexterity in children with spastic Cerebral Palsy.
- Trial name
- SpiManCP (NCT03005938)
- Testing
- Spinal manipulation, Imitation of the spinal manipulation
- Where
- Ukraine
- Volunteers
- 85 people
- Sponsor
- International Clinic of Rehabilitation, Ukraine
Spinal Cord Tumor
Surgical Outcome of Dorsolumbar Intradural Extramedullary Spinal Cord Tumors
Primary spinal cord tumors constitute 2-4% of all central nervous system neoplasms; they are classfied as extradural, intradural extramedullary (IDEM: 65%), and intramedullary The most commonly seen IDEM tumors are schwannomas…
- Trial name
- NCT05678608
- Testing
- surgical excision
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Gait Disorder, Sensorimotor, Burns
Clinical Utility of Robot-Assisted Gait Training in Patients With Spinal Cord Injury Caused by Electrical Burns: A Case Report
Robot-assisted gait training has been effective in several diseases. Nevertheless, evidence supporting the efficacy of such training in burn patients remains insufficient.
- Conditions
- Gait Disorder, Sensorimotor, Burns, Spinal Cord Injuries
- Trial name
- NCT05883917
- Testing
- robot assisted gait training
- Volunteers
- 2 people
- Sponsor
- Hangang Sacred Heart Hospital
Ankylosing Spondylitis
Dose-Ranging Study Of Tofacitinib In Adults With Active Ankylosing Spondylitis
This is the first study of oral tofacitinib in adults with active ankylosing spondylitis. It is designed to obtain information on the efficacy and safety of 3 different doses of tofacitinib.
- Trial name
- NCT01786668
- Testing
- Tofacitinib 2 mg, Tofacitinib 5 mg, Tofacitinib 10 mg
- Where
- 67 sites in United States, Canada and 8 more
- Volunteers
- 208 people
- Sponsor
- Pfizer
Scoliosis; Adolescence, Degenerative Disc Disease
Personalized Spine Study Group Registry
As a registry, the primary objective of the study is a data collection initiative. The study will collect clinical and radiographic outcomes of patients implanted with Medicrea's PSR.
- Conditions
- Scoliosis; Adolescence, Degenerative Disc Disease, Spinal Fusion, Kyphoscoliosis
- Trial name
- NCT03843476
- Testing
- Patient Specific Rod
- Sponsor
- Medicrea, USA Corp.
Ankylosing Spondylitis
Safety and Tolerability of AIN457 in Adults (18-65 Years) With Moderate to Severe Ankylosing Spondylitis
This study is designed as an extension study to the proof-of-concept trial CAIN457A2209 in patients with moderate to severe ankylosing spondylitis and aims to provide continuous treatment with AIN457 for patients in the core…
- Trial name
- NCT01109940
- Testing
- AIN457A
- Where
- 15 sites in United States, Germany and 2 more
- Volunteers
- 39 people
- Sponsor
- Novartis Pharmaceuticals
IBM, Inclusion Body Myositis
Imaging Assessment of Swallowing and Speech Muscles in Inclusion Body Myositis
This study will evaluate whether neuromuscular ultrasound and MRI can be used as imaging markers of bulbar involvement and swallowing dysfunction in individuals with inclusion body myositis (IBM).
- Conditions
- IBM, Inclusion Body Myositis, Myopathy, Myositis
- Trial name
- NCT07823101
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Psoriatic Arthritis (PsA), Subclinical Right Ventricular Systolic Dysfunction
Right Ventricular Strain in Detecting Subclinical Right Ventricular Systolic Dysfunction in Psoriatic Arthritis Patients: Relation to Serum Endostatin Level
The aim is to assess early right ventricular systolic dysfunction in psoriatic arthritis patients using RV strain echocardiography
- Trial name
- NCT07046312
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Ankylosing Spondylitis
The Effects of Clinical Pilates Training in Patients With Ankylosing Spondylitis
The objective of this study was to examine the effects of 8-week clinical Pilates training on disease-specific indices, core stability, and balance in ankylosing spondylitis (AS) patients.
- Trial name
- NCT04292028
- Testing
- Pilates, Home exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Dokuz Eylul University
Spinal Anaesthesia, Anxiety State
The Effect of Virtual Reality and Music Recital on Anxiety and Agitation in Patients Undergoing Spinal Anaesthesia
This study will be carried out in patients undergoing spinal anaesthesia. The effects of virtual reality and music playback on anxiety and agitation in patients will be evaluated.
- Conditions
- Spinal Anaesthesia, Anxiety State, Surgery, Ajitation
- Trial name
- NCT06765967
- Testing
- displaying virtual reality images, music playback
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Kafkas University
Cervical Degenerative Disc Disease, Cervical Stenosis
Minimally Invasive Posterior Decompression of the Cervical Spine
Degenerative stenosis of the cervical spinal canal may be caused by the compression of the posterior part of the dural sac and spinal cord by the hypertrophied ligamentum flavum and facet joints, by the compression of the…
- Conditions
- Cervical Degenerative Disc Disease, Cervical Stenosis, Posterior Spine Surgery
- Trial name
- NCT06995300
- Testing
- minimally invasive decompression via the posterior approach
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- N.N. Priorov National Medical Research Center of Traumatology and Orthopedics
SCI - Spinal Cord Injury
tDCS and VI to Treat Neuropathic Pain and Function in SCI
Transcranial direct current stimulation (tDCS) over the primary motor cortex (M1) will be applied for patient who suffer from neuropathic pain following spinal cord injury The tDCS treatment will be coupled with a video of a man…
- Trial name
- NCT03052244
- Testing
- tDCS+VI
- Volunteers
- 100 people
- Sponsor
- Loewenstein Hospital
Guillain-Barre Syndrome
sCD163 as a Potential Biomarker in Guillain- Barré Syndrome
Guillain- Barré syndrome (GBS) is an acute inflammatory demyelinating polyneuropathy (AIDP) that often is triggered by an infection. GBS is characterized by progressing weakness and numbness and loss of tendon of reflexes.
- Trial name
- GBS (NCT02582853)
- Testing
- Lumbar puncture, Blood Sample
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Aarhus
Pain, Postoperative
Comparing Analgesic Effects of Wound Infiltration Using Bupivacaine, Tramadol, and Tramadol Plus Bupivacaine
The goal of this study's clinical trial is to compare in post-operative analgesic effectiveness of wound infiltration using bupivacaine, tramadol, and tramadol plus bupivacaine in patients undergoing elective cesarean section…
- Trial name
- NCT06076707
- Testing
- bupivacain-tramadol
- Where
- Ethiopia
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Wollo University
Axial Spondyloarthritis
Factors for the Onset and Course of Axial Spondylitis
In a research project, investigators want to study the course of the disease of axial spondylitis: the causes of disease onset, prognosis, and treatment effects.
- Trial name
- EISPA (NCT06594107)
- Where
- 2 sites in Sweden
- Volunteers
- 1,000 people
- Sponsor
- Karolinska Institutet
Postoperative Pain
Spinal Hydromorphone Versus Morphine for Post-Cesarean Delivery Analgesia
Morphine is usually used for pain relief after cesarean delivery. However, sometimes it is not available, the patient might be allergic to morphine or intolerant to its side effects.
- Trial name
- NCT03592992
- Testing
- Spinal Hydromorphone, Spinal Morphine
- Where
- Canada
- Volunteers
- 126 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Frontotemporal Dementia, Amyotrophic Lateral Sclerosis
Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
Background: Neurodegenerative disorders can lead to problems in movement or memory. Some can cause abnormal proteins to build up in brain cells.
- Conditions
- Frontotemporal Dementia, Amyotrophic Lateral Sclerosis, Progressive Supranuclear Palsy
- Trial name
- NCT03225144
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Incomplete Spinal Cord Injury
Powered Exoskeleton Combined With Functional Electrical Stimulation in Clinical Practice
After partial spinal cord injury, gait deficits may be present and often remain even after intensive rehabilitation. New robotic technologies have recently emerged to help augment the extent of rehabilitation.
- Trial name
- NCT04568928
- Testing
- OLTP/PE + FES
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Laval University
Spinal Cord Injuries, Neuropathic Pain
Virtual Walking Therapy for Neuropathic Pain Following Incomplete Spinal Cord Injury
The purpose of this study is to determine if playing a virtual reality walking game can help improve neuropathic pain in adults with incomplete spinal cord injury.
- Trial name
- NCT06330181
- Testing
- VR Game 1, VR Game 2
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Texas A&M University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.