Clinical trials: Spinal
Lumbar Spinal Stenosis
Feasibility Study of NL-Prow Interspinous Spacer to Treat Lumbar Spinal Stenosis
The purpose of the study is to evaluate the clinical safety and feasibility of the NL-Prow™ Interspinous Spacer implant and insertion procedure in the treatment of lumbar spinal stenosis
- Trial name
- NCT01053364
- Testing
- NL-Prow interspinous spacer implant
- Where
- Czechia
- Volunteers
- 6 people
- Sponsor
- Non-Linear Technologies
Scoliosis Idiopathic Adolescent Treatment
Myofascial and Articular Treatment of Adolescent Idiopathic Scoliosis
Randomized controlled trial of participants with scoliosis into standard treatment with observation/bracing and the other group will have the added treatment of dynamic myofascial manipulation for 6 months.
- Trial name
- NCT05423509
- Testing
- Dynamic myofascial manipulation, Standard AIS treatment with observation or bracing
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Lumbar Spine Disease
Efficacy of Motor Control Exercise Program After Lumbar Spinal Decompression Surgery
The study will be conducted with volunteer patients who have undergone lumbar decompression surgery and who are followed up by the Neurosurgery outpatient clinic of Fethiye State Hospital.
- Trial name
- NCT06014632
- Testing
- Rehabilitation, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Muğla Sıtkı Koçman University
Degenerative Disc Disease
Titanium Surgical Mesh and MOSS-Miami Screws for Lumbar Fusion.
The purpose of this study is to determine the clinical success of DePuy Spine Titanium Surgical Mesh with MOSS Miami Spinal Fixation System Pedicle Screws in the treatment of one or two levels of degenerative disc disease of the…
- Trial name
- NCT00215319
- Testing
- Lumbar I/F with cage and pedicle screws
- Where
- 2 sites in United States
- Volunteers
- 139 people
- Sponsor
- DePuy Spine
Degeneration of Lumbar Intervertebral Disc
Qualitative Pain Measurement at Patients With Degenerative Low Back Pain
The purpose of the study is: to measure sensitization of the nociceptive system at patients with low back pain in order to carry out a necessary surgical procedure to examine a possible association between low back pain and…
- Trial name
- NCT01980576
- Where
- Denmark
- Volunteers
- 1 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Ankylosing Spondylitis
Effects of Aerobic Training in Patients With Ankylosing Spondylitis
This is a randomized controlled trial with blinded assessor on the effects of aerobic exercise (walking)in patients with Ankylosing Spondylitis.
- Trial name
- NCT01586650
- Testing
- aerobic training, Stretching exercises
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Federal University of São Paulo
Knee Osteoarthristis, Hip Osteoarthritis
Clinical Validation of SMARTDIAGO for Remote Functional Assessment of Musculoskeletal Conditions
Clinical validation of SMARTDIAGO, an artificial intelligence-based system for remote functional assessment of patients with musculoskeletal disorders and functional frailty.
- Conditions
- Knee Osteoarthristis, Hip Osteoarthritis, Spine Disease, Shoulder Disease
- Trial name
- SMARTDIAGO (NCT07880210)
- Testing
- SMARTDIAGO Remote Functional Assessment
- Where
- 2 sites in Chile
- Volunteers
- 350 people
- Sponsor
- University of Chile
Obesity, Morbid, Back Pain
THE EFFECT OF FAST WEIGHT EFFICIENCY AFTER LAPAROSCOPIC SLEEVE GASTRECTOMY ON THE COBB ANGLE IN MORBID OBESE PATIENTS
Obesity has become an increasingly common health problem today. In this context, although many anatomical, physiological and metabolic problems arising from obesity in morbid obese patients are tried to be solved in daily…
- Conditions
- Obesity, Morbid, Back Pain, Scoliosis
- Trial name
- NCT04844320
- Testing
- Cobb angle measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Lumbar Disc Herniation
Effect of Pulsed Mode Radiofrequency as a Treatment of Lumbar Disc Related Radicular Pain on Tumor Necrotic Factor α Level
Lumbar radiculopathy is a term that describes symptoms of pain, numbness, and/or weakness that radiate along the sciatic nerve from the lower back to the buttocks and leg (1).
- Trial name
- NCT05288920
- Testing
- Radiofrequency pulsed mode on dorsal root ganglion combined with transforaminal steroids injection, Transforaminal injection of Steroids alone
- Where
- 2 sites in Egypt
- Volunteers
- 80 people
- Sponsor
- Beni-Suef University
Chronic Nonspecific Low-back Pain, CNSLBP
Effects of Virtual Reality Exergames Versus Spinal Manipulation in Chronic Nonspecific Low Back Pain
The goal of this clinical trial is to compare the acute effects of virtual reality exergames (VR-EXG) and spinal manipulation on pain, kinesiophobia, mood states, functional disability and lumbar range of motion in individuals…
- Trial name
- NCT07876960
- Testing
- Virtual Reality, Spinal manipulation
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Lumbar Radiculopathy, Discogenic Lumbosacral Radiculopathy
Effect of Trans-spinal Electromagnetic Neuromodulation in Treatment of Patients With Discogenic Lumbosacral Radiculopathy
Purposes of the study To investigate the effect of adding Trans-spinal Electromagnetic Neuromodulation to conventional physical therapy in patients with Discogenic Lumbosacral Radiculopathy
- Trial name
- NCT07743424
- Testing
- Trans-spinal Electromagnetic Neuromodulation, Conventional physical therapy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Yara Aboelazm Abd Elaziz Mohamed
Cervical Spondylosis
Magnetic Therapy and Cervical Stabilization Exercises in Cervical Spondylosis
The purposes of this study are to Investigate adding low frequency high intensity magnetic therapy to cervical stabilization exercises on pain intensity, function, ROM, cervical endurance, and cervical proprioception errors in…
- Trial name
- NCT05734924
- Testing
- low Frequency High Intensity magnetic therapy
- Volunteers
- 80 people
- Sponsor
- Delta University for Science and Technology
Intraspinal Tumor, Juxtamedullary Tumor
Multicenter Trial on Surgical Outcome and Quality of Life in Juxta-medullary Tumors
Primary objectives: Primary objectives are to assess and define benchmarks of the surgical outcome in the form of extent of resection, functionality, and quality of life after resection of juxta medullary tumors Secondary…
- Trial name
- EURJMT (NCT07056023)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University Hospital Muenster
Herniated Disc, Radiculopathy
Slotted Hole Versus Fixed Hole C-Tek
The purpose of this study is to compare the fusion rates between the EBI, LLC C-Tek™ Anterior Cervical Plate, Slotted Hole Design versus the Fixed Hole Design.
- Conditions
- Herniated Disc, Radiculopathy, Spondylolysis
- Trial name
- NCT00585923
- Testing
- Fixed hole C-Tek™ Plate, Slotted hole C-Tek™ Plate
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- Zimmer Biomet
Ankylosing Spondylitis, Exercise Training
Respiratory Training in Individuals with Ankylosing Spondylitis
This study was designed to investigate and compare the effects of standard diaphragmatic breathing and physiotherapy exercises versus 360-degree expandable diaphragmatic breathing and physiotherapy exercises on respiratory…
- Conditions
- Ankylosing Spondylitis, Exercise Training, Diaphragm, Mobility
- Trial name
- NCT06490796
- Testing
- Expanded diaphragm exercise, Standard diaphragm exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Izmir University of Economics
Cerebral Palsy, Spinal Muscular Atrophy
Pediatric Powered Wheelchair Standing Devices: An Exploratory Study
For children who use a power wheelchair, a powered wheelchair standing device (PWSD) may be considered for daily use. A PWSD allows a child to electronically move between sitting and standing and can be driven in either position.
- Conditions
- Cerebral Palsy, Spinal Muscular Atrophy, Spinal Cord Injuries, Spina Bifida
- Trial name
- NCT05117827
- Testing
- Power Wheelchair Standing Device
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Grand Valley State University
Injuries, Spinal Cord, Pain
Levetiracetam in Chronic Neuropathic Pain Following Spinal Cord Injury
Purpose: To evaluate the efficacy and safety of levetiracetam on chronic neuropathic pain after spinal cord injury, and to examine its effect on spasms and evoked pain.
- Trial name
- NCT00252954
- Testing
- Levetiracetam
- Where
- 3 sites in Denmark
- Volunteers
- 36 people
- Sponsor
- Danish Pain Research Center
Psoriatic Arthritis
Efficacy and Safety Study of Apremilast to Treat Active Psoriatic Arthritis (PsA)
The purpose of this study is to determine whether apremilast is safe and effective in the treatment of patients with psoriatic arthritis who have not been previously treated with DMARDs.
- Trial name
- PALACE4 (NCT01307423)
- Testing
- Apremilast 20mg, Apremilast 30mg
- Where
- 118 sites in United States, Australia and 16 more
- Volunteers
- 529 people
- Sponsor
- Amgen
Rheumatoid Arthritis, Crohn's Disease
The RATIO: Registry of Infections and Lymphoma in Patients Treated With TNF-a Antagonists
The RATIO registry is a French registry designed by a multidisciplinary group to collect data on opportunistic and severe bacterial infections and lymphoma in patients treated with TNF-a antagonists ( infliximab, etanercept and…
- Conditions
- Rheumatoid Arthritis, Crohn's Disease, Ankylosing Spondylitis, Psoriasis
- Trial name
- NCT00224562
- Testing
- TNF-alpha antagonists
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lumbar Spine Disease, Lumbar Disc Herniation
Perioperative Local Anesthesia Block in Spine Surgery
The purpose of the this study to evaluate the feasibility, safety, and efficacy of a fluoroscopically-guided dorsal ramus block placed by the operative neurosurgeon prior to lumbosacral surgery.
- Conditions
- Lumbar Spine Disease, Lumbar Disc Herniation, Lumbar Spinal Stenosis
- Trial name
- NCT05094427
- Testing
- Preoperative fluoroscopically-guided dorsal ramus block placed by the operative neurosurgeon
- Where
- United States
- Volunteers
- 232 people
- Sponsor
- Columbia University
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