Clinical trials: Spinal Aneshtesia
Post-spinal Hypotension, Orthopedic Surgery
Ketamine for Preventing Post-Spinal Hypotension in Orthopedic Surgery
This randomized, double-blind, controlled clinical trial investigates the efficacy of a sub-anesthetic dose of ketamine (0.5 mg/kg IV) in preventing post-spinal hypotension in patients undergoing elective orthopedic surgeries…
- Conditions
- Post-spinal Hypotension, Orthopedic Surgery, Spinal Aneshtesia
- Trial name
- NCT06995690
- Testing
- Ketamine, Normal Saline
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Pediatrics, Spinal Aneshtesia
A Comparative Study Between Age-Based and Weight-Based Bupivacaine Dosing for Pediatric Spinal Anesthesia in Children Undergoing Elective Infra-Umbilical Surgeries
This prospective randomized double-blinded controlled trial will include 60 pediatric patients aged 1 - 6 years old, both sexes, with American society of anesthesiologists (I and II) and undergoing elective infra-umbilical…
- Conditions
- Pediatrics, Spinal Aneshtesia, Infraumbilical Surgeries
- Trial name
- NCT07035184
- Testing
- Spinal Anesthesia with Bupivacaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Intraoperative Nausea-retching-vomiting Episodes, Spinal Aneshtesia
Routine Antiemetic Prophylaxis for Nonfasted Parturients Undergoing Cesarean Sections Under Spinal Anesthesia
The aim of this prospective randomized double-blind study is to compare the effectiveness of routine antiemetic prophylaxis for the prevention of intraoperative nausea and vomiting (IONV) in non-fasted parturients undergoing…
- Conditions
- Intraoperative Nausea-retching-vomiting Episodes, Spinal Aneshtesia, Ceserean Section, Antiemetic Therapy
- Trial name
- NCT07740577
- Testing
- Ondansetron 4mg, metoclopramide
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Sanliurfa Education and Research Hospital
Spinal Aneshtesia, Unilateral Spinal Anesthesia
Predictors of Unilateral Spinal Block Success
This prospective observational study aims to determine the factors affecting the success of unilateral spinal anesthesia in patients undergoing orthopedic lower extremity surgery.
- Conditions
- Spinal Aneshtesia, Unilateral Spinal Anesthesia, Regional Anaesthesia
- Trial name
- UNISS (NCT07581561)
- Where
- Turkey (Türkiye)
- Volunteers
- 318 people
- Sponsor
- Izmir City Hospital
Spinal Surgery, Spinal Aneshtesia
Spinal Anaesthesia Success in Patients With Previous Lumbar Spine Surgery
The goal of this observational study is to compare spinal anaesthesia success in adults with and without previous lower back surgery.
- Trial name
- NCT07852767
- Testing
- spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Celal Kaya
Cesarean Delivery Affecting Newborn, Acidosis
Ephedrine Versus Norepinephrine and Fetal Acid-Base Status During Cesarean Delivery Under Spinal Anesthesia
This study compares ephedrine and norepinephrine for the treatment of low blood pressure (hypotension) that may occur during cesarean delivery under spinal anesthesia.
- Conditions
- Cesarean Delivery Affecting Newborn, Acidosis, Maternal Hypotension, Spinal Aneshtesia
- Trial name
- NEO-FET (NCT06921473)
- Testing
- Norepinephrine, Ephedrine
- Where
- Turkey (Türkiye)
- Volunteers
- 155 people
- Sponsor
- mehmet özkılıç
Anesthesia, Spinal Aneshtesia
Renal Functions in Preeclamptic Pregnant Women Using Neutrophil Gelatinase-associated Lipocalin (NGAL) and Standard Renal Function Tests
Acute kidney injury (AKI) is a significant postoperative complication. Risk factors for AKI include impaired renal perfusion, decreased functional renal reserve, as well as advanced age, peripheral arterial disease, diabetes…
- Conditions
- Anesthesia, Spinal Aneshtesia, Acute Kidney Failure, Spinal Anesthesia Induced Hypotension
- Trial name
- NCT07015359
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Nihan Aydin Guzey
Knee Surgery, Pelvic Surgery
ED50 of Dexmedetomidine as an Adjuvant to 0.5% Hyperbaric Bupivacaine 12.5 mg for Spinal Anesthesia in Hip and Knee Surgery: An Up-and-Down Method Approach
Determine ED50 dexmedetomidine adjuvant that can provide spinal anesthetic sensory blockade duration of 200 minutes on knee and pelvis surgery with up-and-down method.
- Conditions
- Knee Surgery, Pelvic Surgery, Spinal Aneshtesia
- Trial name
- NCT07144215
- Testing
- Dexmedetomidine 3 mcg, Dexmedetomidine 4 mcg, Dexmedetomidine 5 mcg
- Where
- Indonesia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Spinal Aneshtesia, Hypotension After Spinal Anesthesia
Comparing Two Different Norepinephrine Infusion Rates for Prophylaxis Against Spinal-induced Hypotension in Elderly
The current study aims to determine whether norepinephrine infusion rate (0.07 mcg/kg/min) is non-inferior to the higher dose (0.1 mcg/kg/min) in maintaining intraoperative blood pressure maintaining blood pressure of elderly…
- Conditions
- Spinal Aneshtesia, Hypotension After Spinal Anesthesia, Elderly (People Aged 65 or More)
- Trial name
- NCT07077265
- Testing
- Norepinephrine (0.1 μg/kg/min), Norepinephrine (0.07 μg/kg/min)
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Kasr El Aini Hospital
Spinal Aneshtesia, General Anesthetic
Effects of Anesthesia Type on Inflammatory Response
In total knee arthroplasty, surgical and anesthetic procedures can lead to a significant increase in systemic inflammation. This procedure is frequently performed under either general or spinal anesthesia.
- Conditions
- Spinal Aneshtesia, General Anesthetic, Inflammation, Neutrophils
- Trial name
- NCT06984315
- Testing
- The effects of the groups on perioperative inflammation changes were compared.
- Where
- Turkey (Türkiye)
- Volunteers
- 849 people
- Sponsor
- Tokat Gaziosmanpasa University
Post Operative Urinary Retention, Spinal Aneshtesia
Effect of IV Dexamethasone on Post-op Urinary Retention After Spinal Anesthesia
What is this study about? This study is testing whether a common medication called dexamethasone, given through a vein (IV) before surgery, can help prevent a problem called postoperative urinary retention (POUR).
- Trial name
- DEX-PUR (NCT07077850)
- Testing
- Dexamethasone (IV), Normal Saline (0.9% NaCl)
- Where
- Palestinian Territories
- Volunteers
- 1,084 people
- Sponsor
- Al-Quds University
Intraoperative Hypotension, Spinal Aneshtesia
Dural Sac Area-Guided Spinal Anesthesia Dosing for TURP
This randomized controlled study will evaluate whether individualizing the dose of spinal anesthesia according to the ultrasound-derived dural sac cross-sectional area (DSCSA) can improve hemodynamic stability in patients…
- Conditions
- Intraoperative Hypotension, Spinal Aneshtesia, TURP(Transurethral Resection of Prostate)
- Trial name
- NCT07794852
- Testing
- DSCSA-Guided Individualized Spinal Anesthesia Dosing, Bupivacaine, Fentanyl (FEN)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Hypotension Drug-Induced, Spinal Aneshtesia
Effect of Lateral Decubitus Position After Spinal Anesthesia on Hemodynamic Stability in High-Risk Geriatric Patients
Spinal anesthesia is a common and preferred anesthetic technique for lower extremity orthopedic surgery in elderly patients. However, it can cause a significant drop in blood pressure (hypotension), especially in high-risk older…
- Conditions
- Hypotension Drug-Induced, Spinal Aneshtesia, Geriatric, Orthopedic Surgery Patients
- Trial name
- NCT07597148
- Testing
- Lateral Decubitus Positioning, Immediate Supine Positioning
- Volunteers
- 70 people
- Sponsor
- University of Health Sciences Balikesir Hospital Eduation and Research
Umbilical Hernia, Spinal Aneshtesia
Spinal Or General Anesthesia For Umblical Hernia Surgery
In this study, the investigators compared spinal anesthesia under ketofol (ketamine-propofol combination) sedation with general anesthesia in terms of intraoperative and postoperative hemodynamics, respiratory parameters and cost…
- Conditions
- Umbilical Hernia, Spinal Aneshtesia, General Anesthesia
- Trial name
- NCT06426225
- Testing
- General Anesthesia, Spinal Aneshtesia
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Ankara City Hospital Bilkent