Clinical trials: Spinal Anesthesia
Haemodynamic Instability
To Determine the Effectiveness of Saddle Block vs Spinal Anesthesia in TURP
To determine the effectiveness of saddle block vs spinal anesthesia in TURP.
- Trial name
- NCT05285800
- Testing
- 0.5% Hyperbaric Bupivacaine
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hamdard University
Anesthesia, Spinal
The Effect of Spinal Anesthesia on Hemodynamics
In this study, it was planned to provide more stable hemodynamics in geriatric patients with low-dose spinal anesthesia. We will compare 7.5mg hyperbaric bupivacaine with 5mg hyperbaric bupivacaine.
- Trial name
- NCT05896631
- Testing
- 7.5 mg hyperbaric bupivacaine, 5 mg hyperbaric bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Melatonin, Cognitive Dysfunction
Use of Melatonin for Preventing POCD in Transurethral Prostate Resection Under Spinal Anesthesia
This study aims to evaluate the possible effect of melatonin on prevention of cognitive dysfunction in the postoperative period of elderly patients undergoing transurethral resection of the prostate (TURP) under spinal anesthesia
- Conditions
- Melatonin, Cognitive Dysfunction, Postoperative Complications, Prostate Hyperplasia
- Trial name
- NCT03966950
- Testing
- melatonin
- Where
- Brazil
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Cesarean Section, Post Operative Pain
Ilioinguinal Iliohypogastric Nerve Block as Adjunct to Spinal Anesthesia for Cesarean Section
The aim of the present controlled randomized study is to compare between ilioinguinal/iliohypogastric nerve block (IINB) and morphine as adjuncts to spinal anesthesia for cesarean section regarding quality of post-operative…
- Trial name
- NCT06108895
- Testing
- ilio-inguinal/ilio-hypogastric nerve block (IINB), intrathecal morphine
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tanta University
Cesarean Section Complications, Hemodynamic Instability
Norepinephrine in Caesarian Section
Postspinal hypotension is a frequent maternal complication in caesarian delivery under neuraxial anesthesia which is most commonly treated with the administration of phenylephrine infusion.
- Conditions
- Cesarean Section Complications, Hemodynamic Instability, Foetal Stress
- Trial name
- NCT05264870
- Testing
- Norepinephrine
- Where
- Belgium
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Orchiectomy, Spermatic Cord Block
Comparison of Spinal Anesthesia and Spermatic Cord Block for Bilateral Orchiectomy
The goal of this randomized controlled trial is to compare intraoperative pain score, Morphine consumption during 6 and 12 hour after surgery, and postoperative complications between SA and SCB groups in metastatic prostate…
- Conditions
- Orchiectomy, Spermatic Cord Block, Spinal Anesthesia, Pain Score
- Trial name
- NCT06313775
- Testing
- bilateral orchiectomy
- Where
- Thailand
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Sanpasitthiprasong Hospital
Pain
Is the Efficacy of Epidural Steroid Injections Related to the Different Volume Injections?
This study was aimed to investigate the impact of using different epidural volumes. Patients with acute discogenic pain were included in the study.
- Trial name
- NCT02343432
- Testing
- Triamcinolone, Epidural Volume, Bupivacaine
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Neslihan Uztüre
Anesthesia; Sexual, Analgesia
The Effect of Peripheral Nerve Blocks on Postoperative Analgesia in Elective Cesarean Section
The goal of this prospective randomized study was to compare the efficacy of transversus abdominis plane block and transversalis fascia plane block for postoperative analgesia in patients undergoing elective cesarean section…
- Trial name
- NCT05758233
- Testing
- Patients undergoing transversalis fascia plane block, Patients undergoing transversus abdominis plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Shoulder Pain
Effect of Intravenous Dexmedetomidine on Patient Discomfort in Laparoscopic Cholecystectomy Under Spinal Anesthesia.
Laparoscopic cholecystectomy (LC) has been routinely performed under general anesthesia despite the several disadvantages of general anesthesia compared to regional anesthesia.
- Trial name
- RCT (NCT04115449)
- Testing
- Dexmedetomidine, normal saline
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Theodor Bilharz Research Institute
Healthy
Clinical Characteristics of Prilocaine for Spinal Anesthesia in Ambulatory Surgery: Clinical Profile and Efficacy
Introduction: Hyperbaric prilocaine is widely used internationally for outpatient orthopedic and perineal surgery because of its favorable recovery profile compared with other intermediate-acting local anesthetics, such as…
- Trial name
- Prilocaine (NCT07661628)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Virtual Reality
The Effect of Virtual Reality on Patients With Anxiety Over Surgeries Under Spinal Anesthesia
The main purposes of this study are as follows: First, to understand the effect of virtual reality on the subjective feelings of anxiety in patients with orthopaedic lower limb surgery for spinal anesthesia.
- Trial name
- NCT03922009
- Testing
- Virtual Reality
- Where
- Taiwan
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University Hospital
Post Spinal Anesthesia Hypotension
Preoperative Oral Midodrine Versus Intraoperative Intravenous Norepinephrine in Preventing Post-spinal Anesthesia Hypotension in Cesarean Section: A Prospective Double-blind Randomized Clinical Trial
Neuraxial blockade such as spinal anaesthesia can cause severe hypotension due to pharmacological sympathectomy resulting in potential deleterious consequences for the patient, Prevention of this spinal anaesthesia induced…
- Trial name
- NCT06213935
- Testing
- Norepinephrine, Midodrine
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Spinal Anesthesia, Task Sharing in Anesthetic Delivery in Areas With Limited Access to Care
Task-based Credentialing for Medical Officers in Spinal Anesthesia
Test the safety and effectiveness of training medical officers in the provision of spinal anesthesia in a rural hospital context using a non-inferiority randomized trial.
- Trial name
- NCT04438811
- Testing
- delivery of the spinal anesthetic by a trained medical officer, delivery of spinal anesthetic by a consultant anesthetist
- Where
- 4 sites in United States, India
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Postoperative Pain, Complications
A Trial of Closed Hemorrhoidectomy Under Local Perianal Block Versus Spinal Anesthesia
Hemorrhoidectomy can be carried out under several modes of anesthesia. In western country hemorrhoidectomy usually be performed under general anesthesia, however there may be the complications resulted from general anesthesia…
- Conditions
- Postoperative Pain, Complications, Satisfaction
- Trial name
- NCT00925912
- Testing
- spinal block, Perianal block
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Hypotension, Vasopressors
Norepinephrine Versus Ephedrine in Treatment of Hypotension During Spinal Anesthesia for Caesarean Section
Prospective, randomized study, including full term parturients scheduled for caesarean section under spinal anesthesia. Spinal anesthesia was performed in sitting position with a 25 G spinal needle and all patients received 15…
- Conditions
- Hypotension, Vasopressors, Cesarean Section Complications, Anesthesia Complication
- Trial name
- NCT03163407
- Testing
- Norepinephrine, Ephedrine
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Mongi Slim Hospital
Acute Pain, Anesthesia
Effectiveness of Retrolaminar Block in Lumbar Spine Fusion With Multimodal Analgesia
This randomized, blinded, controlled clinical trial aims to evaluate the effectiveness of ultrasound-guided retrolaminar block in reducing postoperative opioid consumption in patients undergoing lumbar spine fusion surgery under…
- Conditions
- Acute Pain, Anesthesia, Lumbar Spine Disease
- Trial name
- RBLUF (NCT07291388)
- Testing
- retrolaminar block
- Where
- Chile
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Postoperative Pain, Anesthesia, Regional
Mid-Transverse Process to Pleural (MTP) Block and Erector Spinal Plan (ESP) Block in Spinal Surgery
Ethics committee approval was taken on October 22, 2019, numbered 19/342. 120 adult patients who will undergo spine stabilization surgery between October 2019 and January 2020 in "Gülhane Training and Research Hospital" were…
- Conditions
- Postoperative Pain, Anesthesia, Regional, Spinal Stenosis
- Trial name
- NCT04193488
- Testing
- MTP block, ESP block, No Block group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Pain, Postoperative
Analgesic Efficacy of Two Adjuvants During Spinal Anaesthesia.
: Pain modulation is very important after operation, particularly for women who undergo caesarean section. A pain-free postoperative period is essential following a caesarean section so new mothers may care for and bond with…
- Trial name
- NCT03458078
- Testing
- Saline Solution, Magnesium Sulfate, Midazolam 5 MG/ML Injection
- Where
- 2 sites in Tunisia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre de Maternité de Monastir
Shivering
Comparison of Prophylactic Use of Tramadol Versus Ketamine for Prevention of Post Spinal Anesthesia Shivering
The goal of this clinical trial is to compare the effectiveness of tramadol versus ketamine in preventing shivering after spinal anesthesia in adult patients (ages 20-65) undergoing elective lower abdominal or inguinoscrotal…
- Trial name
- KETRA4PSAS (NCT07043049)
- Testing
- Tramadol, Ketamine
- Where
- 2 sites in Pakistan
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Syed Muhammad Abbas
Nausea, Vomiting
Minimizing Nausea and Vomiting During Spinals for CS
In parturients undergoing Cesarean section under spinal anesthesia, co-loading of 1 liter of crystalloids, with placing the spinal, along with administering a phenylephrine infusion and glycopyrrolate, enables placing a spinal…
- Trial name
- NCT02872935
- Testing
- Glycopyrrolate, Normal Saline
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Kokila N Thenuwara