Clinical trials: Spinal Anesthesia
Post Spinal Anaesthesia Hypotension, Geriatric Population
Effect of Dexamethasone on Post-spinal Hypotension
The goal of this clinical trial is to learn if intravenous dexamethasone is effective for prevention of post spinal hypotension in geriatric population undergoing orthopedic surgeries.
- Conditions
- Post Spinal Anaesthesia Hypotension, Geriatric Population, Orthopedic Surgeries
- Trial name
- NCT06819436
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Shaheed Mohtarma Benazir Bhutto Institue of Trauma
Low Cardiac Output
Comparative Study of Haemodynamic Changes After Spinal Anaesthesia in Non-obese and Pregnant Women
Obesity has become one of the most common risk factors in obstetric practice with serious anaesthetic implications. Obese pregnants have limited physiological reserves and cardiovascular co- morbidities when compared to non-obese…
- Trial name
- NCT02599376
- Testing
- LiDCOrapid
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Anesthesia
How Fast Are we? Speed of General Versus Spinal Anesthesia for Emergency Cesarean Delivery: A Simulation Based Study
The researchers wish to undertake a simulation based study to compare the speed of general versus spinal anesthesia for emergency cesarean delivery. Minutes may matter for the baby in an emergency.
- Trial name
- NCT00966680
- Testing
- Anesthesia
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Lower Extremity Fracture
Atropine Versus Glycopyrrolate in Preventing Spinal Anesthesia Induced Hypotension in Lower Limb Surgeries
A study to compare between intravenous atropine and glycopyrrolate in preventing spinal anesthesia induced hypotension in patients undergoing major lower limb orthopedic surgeries.
- Trial name
- NCT03580889
- Testing
- Atropine, Glycopyrrolate, Normal Saline Flush, 0.9% Injectable Solution
- Where
- Nepal
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Regional Anaesthesia, Cesarean Section
Dose-response Study of Spinally Administered Ropivacaine for Caesarean Section in Tall Parturients
The main goal is to determine the optimum dose of ropivacaine, a local anaesthetic, that provides regional anaesthesia with no or minimum adverse effects (i.e.
- Trial name
- NCT03936790
- Testing
- Ropivacaine, Fentanyl
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Paraskevi Matsota
Hypotension
The Effect of Intravenous Prehydration on the Hemodynamic Status of Healthy Parturients Undergoing Spinal Anesthesia for Cesarean Delivery
Regional anesthesia (spinal, epidural) is considered the method of choice for anesthesia obstetric deliveries because of the ability to use fewer drugs, a more direct experience of childbirth and the capability to provide…
- Trial name
- NCT01835873
- Testing
- Lactated Ringer's, HES 130/0.42
- Where
- Greece
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Paraskevi Matsota
Spinal Anesthesia
Spinal Anesthetic for Hip and Knee Replacement Surgery - Intrathecal Morphine or Hydromorphone
In the current healthcare system, a short length of stay is paramount, for medical, functional, and financial reasons. Most patients undergoing hip and knee replacement at Hôpital Montfort institution receive spinal anesthetic…
- Trial name
- NCT04280939
- Testing
- spinal anesthesia
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hopital Montfort
Analgesia
Analgesic Effect of Bupivacaine Plus Ketamine Versus Bupivacaine Alone in Transversalis Fascia Plane Block
The objective of this study is to compare the efficacy of transversalis fascia plane block using bupivacaine and ketamine versus bupivacaine alone for pain management after cesarean section under spinal anaesthesia.
- Trial name
- TFBP (NCT06935669)
- Testing
- Ketamine, Bupivacaine, Bupivacain
- Where
- Egypt
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Anxiety, Midazolam Overdose
Effect of Aromatherapy on Perioperative Anxiety Level in Cesarean Sections
Spinal anesthesia has been accepted as the first choice for elective cesarean section due to its easy application technique and elimination of the risks of difficult intubation and aspiration.
- Conditions
- Anxiety, Midazolam Overdose, Breast Feeding
- Trial name
- NCT05334537
- Testing
- Aromatherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Anesthesia; Reaction
Study of Comparison of the Effectiveness of Three Diagrams for Sedation in Spinal Anesthesia
Objective: To determine the efficacy of sedation schemes to sedation in patients about to undergo spinal anesthesia. Methods: Pilot study, clinical type, randomized, prospective, single-blind, in which the investigators compared…
- Trial name
- NCT02136641
- Testing
- Midazolam, Midazolam+Fentanyl Combination, Midazolam+Ketamine Combination
- Where
- Colombia
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidad de Cartagena
Fluid Overload, Anesthesia; Adverse Effect, Spinal and Epidural
Can Vena Cava Ultrasound Guided Volume Repletion Prevent Spinal Induced Significant Hypotension in Elective Patients?
Aim of this study is to determine whether Inferior Vena Cava analyzed by trans-thoracic echocardiography is an effective method to guide titrated fluid repletion in non critical patients, in order both to decrease post procedural…
- Conditions
- Fluid Overload, Anesthesia; Adverse Effect, Spinal and Epidural, Regional Anesthesia Morbidity
- Trial name
- NCT02271477
- Testing
- Ultrasound-guided volemic repletion
- Where
- Switzerland
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Ilioinguinal Nerve Block
The Effects of Ilioinguinal Nerve Block on Chronic Pain in Patients in Inguinal Hernia With Spinal Anesthesia
Regional anesthesia is a popular anesthetic method in patients who will undergo an inguinal hernia operation. Researchers known that pain in the operating area is a complaint that impairs the quality of life for patients in the…
- Trial name
- NCT04295629
- Testing
- Research on the effects of Ilioinguinal Nerve Block on Chronic Pain in Patients who undergo Inguinal Hernia with Spinal Anesthesia, Ilioinguinal nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Anesthesia
Fentanyl Versus Morphine in Spinal Anesthesia for Caesarian Section - Study on Analgesia, Side Effects and Patient 's Satisfaction
Intrathecal morphine and fentanyl are used for anesthesia and perioperative pain management in caesarian section. Despite the fact that spinal Fentanyl is better tolerated, might not be enough for postoperative pain control.
- Trial name
- FvMinSA (NCT05533229)
- Testing
- Fentanyl, Morphine
- Where
- Romania
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Dr. Mihai Octavian Botea
Post-Dural Puncture Headache
Bilateral Sphenopalatine Ganglion Block With or Without Bilateral Greater Occipital Nerve Block for Treatment of Obstetric Post-Dural Puncture Headache
Post-dural puncture headache is a common complication, following neuraxial techniques. The obstetric population is particularly prone to PDPH. Therefore, treatment of PDPH is a key issue in obstetric anesthesia.
- Trial name
- NCT04844229
- Testing
- Bilateral transnasal sphenopalatine ganglion block., Bilateral ultrasound guided greater occipital nerve block.
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Shivering
Comparative Study Between the Prophylactic Intravenous Administrations of Acetaminophen vs Dexamethasone vs Pethidine Regarding the Incidence of Shivering Induced by Single Shot Spinal Anesthesia in the Orthopedic Surgeries of the Lower Limbs
Single Shot Spinal anesthesia (SSSA) is associated with considerable perioperative shivering and can be challenging to treat. Some pharmacologic agents like N-methyl d-aspartate receptor antagonists, magnesium sulfate and opioid…
- Trial name
- NCT05284409
- Testing
- Pethidine, Acetaminophen, Dexamethasone
- Where
- Egypt
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hemodynamic Instability and Shivering
Comparative Study Between Intravenous Granisetron and Ondansetron on Their Effect on Hemodynamics and Shivering After Spinal Anesthesia in Elective Cesarean Delivery
Spinal anesthesia is commonly used in cesarean section surgeries . The most important adverse effects of spinal anesthesia are hypotension and bradycardia caused by sympathetic blockade, with an incidence of about 55-100% .
- Trial name
- NCT06437236
- Testing
- ondansetron, granisetron
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Effects of; Anesthesia, in Labor and Delivery, Pregnancy
Effects of Analgesic Techniques on Duration of Spontaneously Laboring Patients
The purpose of this study is to determine if there is a difference in the duration of the first stage of labor in nulliparous women in spontaneous labor with whom analgesia is maintained with a combined spinal epidural (CSE)…
- Conditions
- Effects of; Anesthesia, in Labor and Delivery, Pregnancy, Prolonged First Stage of Labor
- Trial name
- NCT01982838
- Testing
- Epidural de novo, CSE
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Cardiac Output
The Effect of Ondansetron on Cardiac Output in Elective Cesarean Deliveries
Ondansetron is a medication routinely given to mothers having cesarean deliveries to help prevent and treat nausea and vomiting.
- Trial name
- NCT01841606
- Testing
- Ondansetron, Normal saline
- Where
- Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Spinal Anesthesia, Cesarean Section
Does the Addition of Epinephrine Prolong the Duration of Spinal Anesthesia for Repeat Cesarean Section?
The purpose of this study is to investigate whether the addition of a medication called epinephrine to spinal medications prolongs the duration of the anesthesia.
- Trial name
- NCT02369510
- Testing
- Low-dose epinephrine, High-dose epinephrine, No epinephrine
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Fetal Distress
Evaluation of Copeptin Levels in Elective Cesarean Section With Different Anesthetic Technique
In this study, investigators aimed to investigate the effects of general and spinal anesthesia techniques on copeptin levels during cesarean section and their relation with fetal distress.
- Trial name
- NCT03536910
- Testing
- Copeptin
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University