Clinical trials: Spinal Anesthesia
Anesthesia, Pregnancy Related
Upper vs Lower Extremity BP in Spinal Cesarean Using ClearSight
This is a single-center, prospective observational study in patients undergoing cesarean delivery under spinal or combined spinal-epidural anesthesia.
- Conditions
- Anesthesia, Pregnancy Related, Blockades Neuromuscular
- Trial name
- NCT07685730
- Testing
- ClearSight
- Where
- United States
- Volunteers
- 327 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Adjuvants, Anesthesia, Subarachnoid Block
Intrathecal Nalbuphine Versus Intrathecal Tramadol in Subarachnoid Block for Lower Limb Orthopaedic Surgeries
This study compares the use of intrathecal nalbuphine versus intrathecal tramadol as adjuvant agents to local anaesthetics in subarachnoid block for lower-limb orthopaedic surgeries.
- Trial name
- NCT07294352
- Testing
- Intrathecal tramadol with spinal anesthsia, Intrathecal nalbuphine and spinal anesthesia
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CMH Lahore Medical College and Institute of Dentistry
Melatonin, Cognitive Dysfunction
Use of Melatonin for Preventing POCD in Transurethral Prostate Resection Under Spinal Anesthesia
This study aims to evaluate the possible effect of melatonin on prevention of cognitive dysfunction in the postoperative period of elderly patients undergoing transurethral resection of the prostate (TURP) under spinal anesthesia
- Conditions
- Melatonin, Cognitive Dysfunction, Postoperative Complications, Prostate Hyperplasia
- Trial name
- NCT03966950
- Testing
- melatonin
- Where
- Brazil
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Pregnancy, Labor Pain
Does Ultrasound of the Spine Improve Labor Epidurals/Spinal Anesthesia in Obstetric Patients?
The investigators are interested in determining the utility of ultrasound of the spine for labor epidurals or spinal anesthesia for women in labor or having a cesarean delivery.
- Trial name
- NCT01243216
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Breastfeeding
Evaluation of Breastfeeding Success and Self-Efficacy in Mothers Giving Birth Via Vaginal Delivery or Cesarean Section
This cross-sectional observational study was conducted to compare breastfeeding success and breastfeeding self-efficacy levels of mothers who gave birth via vaginal delivery (spontaneous or via epidural analgesia) or cesarean…
- Trial name
- NCT05106634
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Postoperative Shivering, Cesarean Delivery
Intravenous Dexmeditomidine for Prevention of Spinal Anesthesia Induced Shivering.
Intraoperative and post operative shivering is a common problem encountered in operating rooms and recovery suites. Shivering under spinal anesthesia has an incidence of 40-60%.
- Trial name
- NCT05342376
- Testing
- Dexmedetomidine Hydrochloride, Normal Saline
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rehman Medical Institute - RMI
Anesthesia, Spinal
Failure Rate in Spinal Blocks and Determination of Related Factors
Investigators aimed to determine the rates of unsuccessful spinal anesthesia, to determine the factors related to failure and to determine the measures that may be taken to reduce this problem.
- Trial name
- NCT03959644
- Where
- Turkey (Türkiye)
- Volunteers
- 1,431 people, healthy volunteers welcome
- Sponsor
- Bozyaka Training and Research Hospital
Obstetric Anesthesia Problems
Preloading to Prevent Hypotension During Cesarean Section
Whether the usage of non-invasive arterial blood pressure monitor to guide fluid therapy in caesarean section can effectively reduce the incidence of hypotension and fetal complications.
- Trial name
- NCT03013140
- Testing
- Fluid therapy, Spinal anaesthesia
- Where
- Taiwan
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Lower Extremity Fracture
Atropine Versus Glycopyrrolate in Preventing Spinal Anesthesia Induced Hypotension in Lower Limb Surgeries
A study to compare between intravenous atropine and glycopyrrolate in preventing spinal anesthesia induced hypotension in patients undergoing major lower limb orthopedic surgeries.
- Trial name
- NCT03580889
- Testing
- Atropine, Glycopyrrolate, Normal Saline Flush, 0.9% Injectable Solution
- Where
- Nepal
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Cesarean Section, Post Operative Pain
Ilioinguinal Iliohypogastric Nerve Block as Adjunct to Spinal Anesthesia for Cesarean Section
The aim of the present controlled randomized study is to compare between ilioinguinal/iliohypogastric nerve block (IINB) and morphine as adjuncts to spinal anesthesia for cesarean section regarding quality of post-operative…
- Trial name
- NCT06108895
- Testing
- ilio-inguinal/ilio-hypogastric nerve block (IINB), intrathecal morphine
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tanta University
Cesarean Section Complications, Regional Anesthesia Morbidity
Novel Predictors of Post Spinal Hypotension in Cesarean Sections: Evaluating Jugular Vein Collapsibility Index and Shock Indices
Jugular vein collapsibility index and shock indices (Shock index, Modified Shock Index, Diastolic Shock Index) may be useful in estimating post spinal hypotension in cesarean section operations.
- Conditions
- Cesarean Section Complications, Regional Anesthesia Morbidity, Hemodynamic Instability, Shock
- Trial name
- NCT05953129
- Testing
- Right Jugular Vein Collapsibility Index
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Anesthesia
Postdural Puncture Headache Relief With Aminophylline and SPGB
The purpose of the study is to compare Sphenopalatine ganglion block (SPGB) and aminophylline in the efficacy and safety management of PDPH.
- Trial name
- NCT05552404
- Testing
- conservative therapy, Aminophylline, trans nasal sphenopalatine ganglion block
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Arthropathy of Hip, Arthropathy of Knee
Evaluation of the Duration of Bupivacaine Spinal Block in Orthopedic Procedures With and Without Epinephrine Wash
Bupivacaine spinal is commonly performed as the primary anesthetic for orthopedic procedures. In some cases the duration of the block is inadequate. An epinephrine wash is sometimes performed to prolong the duration of the block.
- Trial name
- NCT02619409
- Testing
- Bupivacaine Only, EPI25, EPI50 group
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Intraoperative Complications
Liberal Versus Restrictive Fluid Protocols in Adults
The term acute kidney injury (AKI) is used to describe a rapid deterioration (hours to days) of renal function. This rapid deterioration leads to accumulation of plasma waste products, such as urea and creatinine.
- Trial name
- NCT03697330
- Testing
- Ringer lactate
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Spinal Anesthetic Toxicity, Inferior Vena Cava Abnormality
Transthoracic Echocardiography of Inferior Vena Cava Before Spinal Anesthesia Can Predict Hypotension
Study Protocol: Outcome Measurements Primary Outcome The main outcome will be the preoperative performance of the dIVCmax/IVCCI ratio to foresee the incidence of hypotension after spinal anesthesia in a greater extent to that of…
- Conditions
- Spinal Anesthetic Toxicity, Inferior Vena Cava Abnormality, Intraoperative Complications
- Trial name
- NCT03266250
- Testing
- spinal anesthesia
- Where
- Greece
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Shivering, Spinal Anesthesia
Post Operative Shivering Following Anesthesia
The aim of this study is to compare the efficacy of magnesium sulphate, ondansetron, and dexmedetomidine in managing post-spinal anesthesia shivering.
- Trial name
- NCT07377903
- Testing
- Dexmedetomidin, Mg (magnesium sulfate), Ondansetron 8 mg
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Lumbar Disc Herniation, Lumbar Disc Disease
GA + ESP vs. SA + ESP in Lumbar Decompression Surgeries
The purpose of this study is to determine the optimal anesthetic routine for lumbar decompression surgery. General Anesthesia is the standard of care in spine surgery.
- Conditions
- Lumbar Disc Herniation, Lumbar Disc Disease, Lumbar Radiculopathy
- Trial name
- NCT05444751
- Testing
- General anesthetic, SA + ESP
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Realtime Ultrasound
Real Time Ultrasound Guided Spinal Anesthesia in Elderly Patients
In this prospective randomized observational study, investigators aim to compare the efficacy and procedural outcomes of real-time ultrasound guided parasagittal oblique (RTU-PO) and real-time ultrasound guided paramedian…
- Trial name
- NCT04214574
- Testing
- Parasagittal oblique technique (Ultrasound), Paramedian tranverse technique (Ultrasound)
- Where
- Lebanon
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Postspinal Shivering
Intravenous Granisetron Vs Dexmedetomidine on Postspinal in the Cesarean Section.
The Aim of this study is to investigate and compare the efficacy of intravenous Dexmedetomidine (0.3 ug/kg) versus intravenous Granisetron (3 mg) in the prevention of shivering in parturient undergoing cesarean section under…
- Trial name
- NCT06762860
- Testing
- Dexmedetomidine, Granisetron
- Where
- Egypt
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Minia University
Spinal Anesthesia
Measuring Cerebrospinal Fluid (CSF) Glucose Levels in Patients Under Going an Elective Cesarean Section With Spinal Anesthesia
This study will determine the level of glucose (sugar) in the CSF (fluid that surrounds the spinal cord) in 30 subjects having spinal anesthesia for cesarean section using a bedside glucose meter.
- Trial name
- NCT01067560
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of British Columbia