Clinical trials: Spinal Anesthesia for Cesarean Section
Spinal Anesthesia, Post Operative Analgesia
Dexamethasone in Prolonging the Duration of Spinal Anesthesia Among Pregnant Patients
Lower segment C section is one of the most commonly performed surgeries worldwide. It is performed in spinal anesthesia. During Spinal Anesthesia a local anesthetic drug is administered in a space surrounding spinal cord and it…
- Trial name
- NCT07088146
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Medical College
Complications; Cesarean Section, Hypotension
The Effects of Height and Weight Adjusted Dose of Local Anesthetic.
At our centre a conventional dose of 12 mg of hyperbaric bupivacaine in combination with a short acting opioid fentanyl (to increase block density) and a long acting opioid morphine (to provide post-operative pain relief ) is…
- Trial name
- NCT02635555
- Testing
- Phenylephrine
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Pregnant Women, Pain
Hyperbaric Bupivacaine Versus Hyperbaric Prilocaine 2% for Cesarean Section Under Spinal Anesthesia
Over the past 15 years, cesarean delivery is most commonly performed under spinal anesthesia using hyperbaric bupivacaine which provides an adequate sensory and motor block.
- Conditions
- Pregnant Women, Pain, Hypotension
- Trial name
- NCT02973048
- Testing
- Hyperbaric bupivacaine, Hyperbaric prilocaine
- Where
- 2 sites in Belgium
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Ultrasound
Ultrasound Versus Palpation for Spinal Anesthesia Success
Aim is to investigate the difference in number of attempts to place neuraxial block comparing handheld ultrasound versus use of palpation alone for women with impalpable bony landmarks undergoing spinal anesthesia for elective…
- Trial name
- Accuro (NCT03679663)
- Testing
- Ultrasound
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Cesarean Section Complications
IM Neostigmine for Accelerating Bladder Emptying After CS by Spinal Anesthesia
The aim of this study is to assess the efficacy of IM neostigmine (0.5 mg) for acceleration of bladder evacuation and prevention of postoperative urine retention following cesarean delivery carried out under spinal anesthesia
- Trial name
- NCT04364607
- Testing
- Neostigmine, NaCl 0.9%
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Adverse Effect
Intensive Versus Standard Treatment for Hypotension on Maternal Hemodynamics in Preeclamptic Patients
The objective of this study is to investigate the impact of varying maternal blood pressure maintenance targets on maternal hemodynamics in preeclamptic patients following cesarean section.
- Trial name
- NCT06151444
- Testing
- Alpha-Agonist, α-adrenergic receptor agonist
- Volunteers
- 160 people
- Sponsor
- General Hospital of Ningxia Medical University
Pregnancy
Use of Ultrasound in Obstetric Neuraxial Analgesia and Anesthesia Data Base
This is a data base building project on the use of pre-procedure ultrasound for the performance of labor epidural pain relief and spinal anesthesia for cesarean deliveries.
- Trial name
- NCT01192074
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Bradycardia, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Hyoscine Butylbromide for Prevention of Bradycardia During Cesarean Section
The aim of this study is to assess the efficacy of Iv hyoscine butylbromide in preventing Bradycardia during cesarean section under spinal anaesthesia with local anaesthetic and morphine.
- Conditions
- Bradycardia, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use, Cesarean Section Complications
- Trial name
- NCT04069078
- Testing
- Hyoscine Butylbromide 20 Mg/mL Solution for Injection Ampoule, Normal saline
- Where
- Egypt
- Volunteers
- 173 people
- Sponsor
- Assiut University
Cesarean Section
TAP Block With Intrathecal Fentanyl vs. Intrathecal Morphine in Cesarean Delivery
This noninferiority study aims to determine whether transversus abdominis plane (TAP) block with intrathecal fentanyl could provide a noninferior analgesia compared with intrathecal morphine after cesarean delivery under spinal…
- Trial name
- NCT04824274
- Testing
- fentanyl, morphine, Transversus abdominis plane block
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Hospital
Ceserean Section, Obstetric Quality of Recovery
Anesthetic Technique and Quality of Recovery After Cesarean Delivery
The goal of this prospective observational study is to evaluate whether the type of neuraxial anesthesia is associated with postoperative quality of recovery in adult women undergoing cesarean delivery.
- Conditions
- Ceserean Section, Obstetric Quality of Recovery, Neuraxial Anesthesia
- Trial name
- NCT07896733
- Testing
- Spinal anesthesia (heavy bupivacaine), epidural anesthesia, combine spinal epidural anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Marmara University
Complications; Cesarean Section
Spinal Aesthesia in Women With Placenta Previa Percreta
Placenta previa percreta is a dangerous complication during surgery. Due to the high risk of hemorrhage, most parturients with placenta previa have to accept cesarean section.
- Trial name
- SAW (NCT02686242)
- Testing
- spinal anesthesia, general anesthesia
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Air Force Military Medical University, China
Intraoperative Shivering, Ketamine With Shivering
Comparison of Ketamine Plus Dexamethasone Versus Ketamine Alone for Prevention of Severe Shivering After Spinal Anesthesia in Cesarean Section
Shivering is one of the most distressing events of the birth experience for patients. Shivering that occurs with spinal anesthesia is a frequent event, with a reported incidence of up to 50-65%.
- Conditions
- Intraoperative Shivering, Ketamine With Shivering, Dexamethasone for Shivering, Severe Shivering
- Trial name
- NCT06091657
- Testing
- Ketamine Hydrochloride
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Kasr El Aini Hospital
Spinal Anesthesia, Cesarean Section
Fixed Dose Spinal Bupivacaine for Cesarean Delivery
The study is designed to compare the effectiveness of spinal anesthesia performed with fixed dose of hyperbaric bupivacaine regardless of patient's height and weight and anesthesia with the dose of bupivacaine that is adjusted to…
- Trial name
- SpinFix-Bupi (NCT03231436)
- Testing
- Fixed dose of 12.5mg bupivacaine, Height-adjusted dose of bupivacaine
- Where
- Poland
- Volunteers
- 140 people
- Sponsor
- Bartosz Horosz, MD
Spinal Anesthesia, Ultrasonography
Ultrasound Evaluation of Two Anatomic Landmarks in Spinal Anesthesia for Cesarean Section: the Posterior Superior Iliac Spine VS Iliac Crest
Intercristal line as palpation landmarks to identifying the vertebral level is frequently inaccurate.To find more safe and reliable body surface markers and convenient methods to be solved in clinical work.The investigators…
- Conditions
- Spinal Anesthesia, Ultrasonography, Posterior Superior Iliac Spine, Intercristal Line
- Trial name
- USPSISICL (NCT06711601)
- Where
- China
- Volunteers
- 650 people
- Sponsor
- The Third Affiliated Hospital of Guangzhou Medical University
Pregnancy, Cesarean Section, Spinal Anesthesia
The Effectiveness of Binaural Beats on Midazolam Requirement During Cesarean Section With Spinal Anesthesia
Spinal anesthesia is preferred for cesarean section in many institutions due to concerns regarding the potential effects of general anesthetic agents on the fetus.
- Trial name
- NCT07386054
- Testing
- binaural beats, Midazolam
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Hemodynamic Stability
Comparative Analytical Study of Intravenous Bolus Dose of Mephentermine and Phenylephrine for Hemodynamic Stability During Elective Cesarean Section Under Spinal Anesthesia at KIST Medical College and Teaching Hospital
Hemodynamics changes with spinal anesthesia is mainly due to sympathetic block which causes mainly hypotension \& bradycardia. Post spinal hypotension usually leads to various adverse maternal and fetal outcomes.
- Trial name
- NCT05706727
- Testing
- Intravenous bolus dose of Mephentermine and mephentermine, intravenous bolus dose of phenylephrine 50 mcg
- Where
- Nepal
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- KIST Medical and Teaching Hospital
Cesarean Section, Anesthesia, Spinal
Intrathecal Dexmedetomidine vs Epinephrine
Several studies have shown that adding dexmedetomidine or epinephrine to single-dose spinal analgesia preparations improves the length and/or speed of onset of the sensory block and post-operative pain management without…
- Trial name
- NCT06418308
- Testing
- Dexmedetomidine, Epinephrine, Standardized Spinal Mixture
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Complications; Cesarean Section, Anesthesia; Adverse Effect, Spinal and Epidural
Fluid Coloading and the Incidence of Hypotension
This study was conducted to evaluate the effects of rapid crystalloid (Lactated Ringer's solution) or colloid (hydroxyethyl starch; HES) cohydration with a second intravenous access line on the incidence of hypotension and…
- Conditions
- Complications; Cesarean Section, Anesthesia; Adverse Effect, Spinal and Epidural, Other Fluid Overload
- Trial name
- NCT01741610
- Testing
- Cristalloid and colloid coloading
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Postspinal Shivering
Intravenous Granisetron Vs Dexmedetomidine on Postspinal in the Cesarean Section.
The Aim of this study is to investigate and compare the efficacy of intravenous Dexmedetomidine (0.3 ug/kg) versus intravenous Granisetron (3 mg) in the prevention of shivering in parturient undergoing cesarean section under…
- Trial name
- NCT06762860
- Testing
- Dexmedetomidine, Granisetron
- Where
- Egypt
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Minia University
Complications; Cesarean Section, Effects of; Anesthesia, Spinal and Epidural, in Pregnancy
Hemodynamic Effects of Low Dose Spinal Anesthesia for Cesarean Section
We propose to study the effects on hemodynamics (blood pressure, cardiac output, and central venous pressure) of two doses of bupivacaine for spinal anesthesia during cesarean section: a higher dose of 12 mg to a lower dose of…
- Conditions
- Complications; Cesarean Section, Effects of; Anesthesia, Spinal and Epidural, in Pregnancy, Hemodynamic Instability, Personal Satisfaction
- Trial name
- NCT02036697
- Testing
- Bupivacaine 4.5, Bupivacaine 9, Morphine
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba