Clinical trials: Spinal Anesthetic Complications
Complications; Cesarean Section, Anesthesia; Adverse Effect, Spinal and Epidural
Fluid Coloading and the Incidence of Hypotension
This study was conducted to evaluate the effects of rapid crystalloid (Lactated Ringer's solution) or colloid (hydroxyethyl starch; HES) cohydration with a second intravenous access line on the incidence of hypotension and…
- Conditions
- Complications; Cesarean Section, Anesthesia; Adverse Effect, Spinal and Epidural, Other Fluid Overload
- Trial name
- NCT01741610
- Testing
- Cristalloid and colloid coloading
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Postoperative Nausea and Vomiting
Efficacy of PC6 Electroacupuncture in the Prevention of Nausea Vomiting in Caesarean Patient Under Spinal Anaesthesia
To determine the ability of electroacupuncture on PC6 versus sham acupuncture in reducing incidence of intraoperative and postoperative nausea vomiting in parturients who underwent Caesarean delivery under spinal anaesthesia
- Trial name
- NCT04801277
- Where
- Malaysia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Clinical Research Centre, Malaysia
Postoperative Pain
Intravenous Ketamine and Postoperative Pain Following Cesarean Section.
The purpose of this study is to investigate the analgesic effect of low-dose intravenous ketamine in pregnant mothers undergoing cesarean section under Bupivacaine spinal anesthesia.
- Trial name
- NCT03018301
- Testing
- Ketamine, Normal saline
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Anesthesia, Adverse Effect
Comparison of Two Doses of Norepinephrine in Preventing Hypotension After Spinal Anesthesia
The purpose of the study is to determine the more effective intravenous bolus of norepinephrine for maintaining blood pressure during a spinal anesthesia for a cesarean delivery with the fewer side effects.
- Conditions
- Anesthesia, Adverse Effect, Hypotension, Cesarean Section Complications
- Trial name
- NCT03706755
- Testing
- Norepinephrine: 1mcg/kg, Norepinephrine 0,5mcg/kg
- Where
- Tunisia
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Spinal Anesthesia, Nursing
The Effect of Local Dry Heat Applıcatıon and Half Shower on The Development of Urinary Retentıon and Paın
Urinary retention is defined as the inability to empty the bladder spontaneously even though the bladder is full. Although urinary retention is seen in two forms as acute and chronic, acute urinary retention is defined by the…
- Conditions
- Spinal Anesthesia, Nursing, Bladder Retention, Dry Heat Application
- Trial name
- NCT05580289
- Testing
- half-shower and hot pack
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Duzce University
Cesarean Section Complications
Effect of a 20% Reduction in Hyperbaric Bupivacaine Dose on High Spinal Block Incidence in Cesarean Delivery
Effect of a 20% Reduction in Hyperbaric Bupivacaine Dose on High Spinal Block Incidence in Cesarean Delivery: A Risk-Stratified Randomized Controlled Trial.
- Trial name
- NCT07140640
- Testing
- Hyperbaric Bupivacaine HCl 0.5% 12.5 mg, Hyperbaric Bupivacaine HCl 0.5% 10 mg
- Where
- Egypt
- Volunteers
- 666 people, healthy volunteers welcome
- Sponsor
- Aswan University
Preeclampsia, Hypotension
Phenylephrine in Spinal Anesthesia in Preeclamptic Patients
Hypotension remains a common clinical problem after induction of spinal anesthesia for cesarean delivery. Maternal hypotension has been associated with considerable morbidity (maternal nausea and vomiting and fetal/neonatal…
- Trial name
- NCT00458003
- Testing
- Ephedrine, Phenylephrine
- Where
- 2 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pain, Postoperative
The Effect of Bilateral Erector Spina Plane Block on Postoperative Analgesia in Cesarean Section Under SpinalAnaesthesia
Acute pain after cesarean section (SC) can be variable. Untreated pain can affect patients' life quality. Currently regional nerve blocks are frequently used as a part of multimodal analgesia.
- Trial name
- NCT05695625
- Testing
- Spinal anesthesia + bilateral erector spine plane block, Spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Ankara University
Labor Pain, Complications; Cesarean Section
Outcomes of Neuraxial Anesthetic Technique on the Trial of Labor After Cesarean (TOLAC)
To compare the effects of epidural versus combined spinal and epidural (CSE) anesthesia on the success of Trial of Labor After Cesarean (TOLAC).
- Conditions
- Labor Pain, Complications; Cesarean Section, Pregnancy
- Trial name
- NCT02105558
- Testing
- Epidural anesthesia, Combined spinal and epidural anesthesia
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Postoperative Pain
Comparative Study of the Analgesic Effect of Spinal Anesthesia or Infiltration Anesthesia for Hemorrhoidectomy
Background and Objectives: Postoperative analgesia and early recovery are relevant for hospital discharge after hemorrhoidectomy.
- Trial name
- NCT02839538
- Testing
- Local Infiltration, Subarachnoidal block
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Postoperative Pain
Femoral Nerve Block, Periarticular Nerve Group (PENG) Block, and Preoperative IV Fentanyl
The pericapsular nerve group block is a regional anesthetic technique described in 2018, developed primarily in total hip arthroplasties for postoperative analgesia with motor sparing benefits.
- Trial name
- NCT06537323
- Testing
- Femoral nerve block with0.25% bupivacaine guided by ultrasound., PENG block with0.25% bupivacaine guided by ultrasound., Preoperative IV fentanyl 100microgram
- Where
- Egypt
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Aswan University Hospital
Healthy Participants
Rate of Tranexamic Acid Administration on Blood Pressure (RateTXA) Study.
Tranexamic acid is a well-established treatment for post-partum hemorrhage. This study aims to examine the effect of tranexamic acid administration rates on blood pressure changes over 1 minute compared to 10 minutes in healthy…
- Trial name
- RateTXA (NCT06356948)
- Testing
- Tranexamic Acid (TXA)
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Hypotension, Cesarean Section Complications
Norepinephrine to Prevent Hypotension in Ceasrean Delivery
This study will be conducted on 40 healthy women having spinal anesthesia for elective cesarean delivery in the operating rooms at Menoufia university hospital.
- Trial name
- NCT05248932
- Testing
- Norepinephrine bolus, cardiometry, Norepinephrine infusion
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Vasoplegia
Postoperative Hemodynamics Comparison After High Spinal Block With or Without Intrathecal Morphine.
There is paucity of literature on the effects of intrathecal morphine on the postoperative hemodynamics in the cardiac-surgical patients.We planned this study to compare the post-operative hemodynamic effects (particularly the…
- Trial name
- NCT02825056
- Testing
- Bupivacaine, Bupivacaine + Morphine
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Complications; Cesarean Section, Hypotension
The Effects of Height and Weight Adjusted Dose of Local Anesthetic.
At our centre a conventional dose of 12 mg of hyperbaric bupivacaine in combination with a short acting opioid fentanyl (to increase block density) and a long acting opioid morphine (to provide post-operative pain relief ) is…
- Trial name
- NCT02635555
- Testing
- Phenylephrine
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Intraoperative Complications
Liberal Versus Restrictive Fluid Protocols in Adults
The term acute kidney injury (AKI) is used to describe a rapid deterioration (hours to days) of renal function. This rapid deterioration leads to accumulation of plasma waste products, such as urea and creatinine.
- Trial name
- NCT03697330
- Testing
- Ringer lactate
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postoperative Pain After Total Knee Arthroplasty, Postoperative Pain
Postoperative Pain and Analgesic Use After Total Knee Arthroplasty
This prospective observational study evaluates postoperative pain intensity and analgesic consumption in patients undergoing total knee arthroplasty (TKA) under different anesthesia techniques.
- Conditions
- Postoperative Pain After Total Knee Arthroplasty, Postoperative Pain, Analgesic Consumption
- Trial name
- NCT07457814
- Where
- Czechia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tomas Bata Hospital, Czech Republic
Cesarean Section Complications, Spinal Anesthesia
Ultrasound Guided Fluid Loading Before Spinal Anesthesia
Perioperative hypotension is a common complication of spinal anesthesia during cesarean sections. The aim of this study was to evaluate the effectiveness of echoguided correction of hypovolemia through crystalloid preloading on…
- Conditions
- Cesarean Section Complications, Spinal Anesthesia, Hypotension, Hypovolemia
- Trial name
- EHCOPRESPA (NCT07108881)
- Testing
- C, T
- Where
- Tunisia
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Spinal Anesthetic Toxicity, Inferior Vena Cava Abnormality
Transthoracic Echocardiography of Inferior Vena Cava Before Spinal Anesthesia Can Predict Hypotension
Study Protocol: Outcome Measurements Primary Outcome The main outcome will be the preoperative performance of the dIVCmax/IVCCI ratio to foresee the incidence of hypotension after spinal anesthesia in a greater extent to that of…
- Conditions
- Spinal Anesthetic Toxicity, Inferior Vena Cava Abnormality, Intraoperative Complications
- Trial name
- NCT03266250
- Testing
- spinal anesthesia
- Where
- Greece
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Spinal Anesthetic Toxicity, Hypotension Drug-Induced
Comparison of Two Different Norepinephrine Bolus Doses for Management of Spinal Anesthesia-Induced Maternal Hypotension
In this study the investigators will compare two doses of norepinephrine bolus (6 mcg and 8 mcg) in management of maternal hypotensive episode after spinal block during cesarean delivery.
- Conditions
- Spinal Anesthetic Toxicity, Hypotension Drug-Induced, Cesarean Section Complications
- Trial name
- NCT05502146
- Testing
- Noradrenaline Bitartrate, Bupivacaine Hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mersin University