Clinical trials: Spinal Anesthetic Complications
Regional Anesthesia Morbidity, Cesarean Section Complications
Height Adjusted Versus Standardized Dose of Bupivacaine for Spinal Anesthesia
General anesthesia during pregnancy is associated with several major risks including unanticipated difficult airway, pulmonary aspiration, and specific anesthetic effects on the newborn.
- Conditions
- Regional Anesthesia Morbidity, Cesarean Section Complications, Local Anesthetic Complication
- Trial name
- RAMCES (NCT05233462)
- Testing
- standardized dose, adjusted dose
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Caen
Anesthesia; Adverse Effect, Spinal and Epidural, Hypotension
Ephedrine vs. Nor Epinephrine Infusion in Preventing Hypotension After Spinal Anesthesia for Cesarean Section
The purpose of the study is to determine if norepinephrine is more effective as a continuous intravenous (IV) infusion compared to continuous IV ephedrine associated with crystalloid loading for maintaining blood pressure during…
- Conditions
- Anesthesia; Adverse Effect, Spinal and Epidural, Hypotension, Complications; Cesarean Section
- Trial name
- NCT02477501
- Testing
- Norepinephrine, Ephedrine
- Where
- Tunisia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Spinal Anesthesia, Nursing
The Effect of Local Dry Heat Applıcatıon and Half Shower on The Development of Urinary Retentıon and Paın
Urinary retention is defined as the inability to empty the bladder spontaneously even though the bladder is full. Although urinary retention is seen in two forms as acute and chronic, acute urinary retention is defined by the…
- Conditions
- Spinal Anesthesia, Nursing, Bladder Retention, Dry Heat Application
- Trial name
- NCT05580289
- Testing
- half-shower and hot pack
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Duzce University
Pain, Postoperative
Combination Effects of Pregabalin and Dexmedetomidine on Postoperative Pain
Pregabalin and dexmedetomidine have been introduced to manage postoperative pain. The present study aimed to evaluate the effect of the combination of two drugs on pain relief in patients undergoing total knee or hip arthroplasty…
- Trial name
- NCT03512574
- Testing
- Pregabalin, Dexmedetomidine, Pregabalin and dexmedetomidine
- Where
- South Korea
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
Cesarean Section Complications
Effect of a 20% Reduction in Hyperbaric Bupivacaine Dose on High Spinal Block Incidence in Cesarean Delivery
Effect of a 20% Reduction in Hyperbaric Bupivacaine Dose on High Spinal Block Incidence in Cesarean Delivery: A Risk-Stratified Randomized Controlled Trial.
- Trial name
- NCT07140640
- Testing
- Hyperbaric Bupivacaine HCl 0.5% 12.5 mg, Hyperbaric Bupivacaine HCl 0.5% 10 mg
- Where
- Egypt
- Volunteers
- 666 people, healthy volunteers welcome
- Sponsor
- Aswan University
Pain, Postoperative
Transversus Abdominis Plane Block Versus Ilioinguinal Nerve Block for Pain Management in Inguinal Herniorraphy
This study compares efficacy of transversus abdominis plane block and ilioinguinal nerve block for postoperative pain in patients undergoing inguinal herniorraphy with spinal anesthesia.
- Trial name
- NCT02375100
- Testing
- Spinal Anesthesia, Transversus Abdominis Plane Block, Ilioinguinal Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bozyaka Training and Research Hospital
Shivering, Nausea and Vomiting, Postoperative
Dexmedetomidine After Cesarean for the Treatment of Nausea and Shivering
This is a randomized double blinded trial to determine if a small dose of dexmedetomidine can prevent and relieve nausea and shivering, two of the more common complaints after cesarean delivery.
- Trial name
- NCT03370562
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Beth Israel Deaconess Medical Center
Breech Presentation
Impact of Analgesia on Success of External Version: Comparison of Spinal Anesthesia Versus Sedation
At the time of birth, nearly 5% of children are in breech presentation. This type of presentation requires a medical environment and leads to more frequent use of Caesarean sections.
- Trial name
- RaVem (NCT02801201)
- Testing
- Midazolam, Bupivacaine
- Where
- France
- Volunteers
- 186 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Pre-Eclampsia
Restrictive Fluid Therapy in Severe Preeclampsia
Introduction: Pre-eclampsia is a multifactorial syndrome which occurs in hypertension and proteinuria in pregnant women over 20 weeks gestation.
- Trial name
- NCT02214186
- Testing
- Restrictive Fluid Therapy
- Where
- Brazil
- Volunteers
- 46 people
- Sponsor
- University of Sao Paulo General Hospital
Postdural Puncture Headache, Postoperative Nausea and Vomiting
Ondansetron and Dexamethasone for Prevention of PDPH, Nausea, and Vomiting
This prospective, randomized, double-blind, placebo-controlled study was conducted at the Obstetrics and Gynecology Department of El-Minia University Hospital from October 2018 to October 2019.
- Conditions
- Postdural Puncture Headache, Postoperative Nausea and Vomiting, Obstetric Anesthesia Problems
- Trial name
- PDPH-N/V (NCT07068230)
- Testing
- Ondansetron 8mg, Dexamethasone, Saline
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Minia University
Post-Dural Puncture Headache
Optic Nerve Sheath Diameter in Postspinal Headache
This study aims to investigate the relationship between spinal needle size and optic nerve sheath diameter (ONSD) in patients who develop post-dural puncture headache (PDPH) after spinal anesthesia.
- Trial name
- PDPHPatients (NCT06957899)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Konya City Hospital
Knee Osteoarthritis, Arthropathy of Knee Joint
Outcome After Total Knee Arthroplasty Under General or Spinal Anesthesia
Previous retrospective database studies suggest that total knee arthroplasty (TKA) surgery under spinal anesthesia has less complications than when performed under general anesthesia.
- Conditions
- Knee Osteoarthritis, Arthropathy of Knee Joint, Knee Pain Chronic, Rheumatoid Arthritis
- Trial name
- NCT03364088
- Testing
- Spinal anesthesia with tourniquet, Spinal anesthesia without tourniquet, General anesthesia with tourniquet
- Where
- Finland
- Volunteers
- 402 people
- Sponsor
- Riku Antero Palanne
Hypotension, Anesthesia, Local
The Relationship Between Abdominal Circumference: Hip Ratio and Ephedrine Requirement
This prospective observational study aimed to investigate whether there is a relationship between weight, height, BMI, abdominal circumference (AC), hip circumference (HC), and AC-to-hip ratio with the incidence of hypotension in…
- Conditions
- Hypotension, Anesthesia, Local, Cesarean Section Complications
- Trial name
- NCT05382624
- Testing
- Abdominal circumference was measured at the umbilical level in the standing position at the end of a normal expiration.
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Knee Osteoarthritis
Investigation of the Effect of Proximal and Distal Adductor Canal Block in Knee Replacement Surgery
to investigate the effect of adductor canal block applied with two different approaches in the treatment of pain after TKA surgery on pain control and functional mobility.
- Trial name
- NCT06188806
- Testing
- ADDUKTOR CANAL BLOCK, CONTROL GROUP
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Umraniye Education and Research Hospital
Perioperative Anxiety, Perioperative Pain Management
Evaluation of the Effectiveness of Virtual Reality as an Adjunct to Standard Care in Managing Perioperative Anxiety and Pain in Patients Undergoing Lower Limb Orthopedic Surgery Under Spinal Anesthesia
The goal of this clinical trial is to evaluate whether virtual reality (VR) can effectively reduce perioperative anxiety and pain in patients undergoing lower limb orthopedic surgery under spinal anesthesia.
- Conditions
- Perioperative Anxiety, Perioperative Pain Management, Hemodynamic Stability, Satisfaction
- Trial name
- NCT07134764
- Testing
- Virtual reality session
- Where
- Tunisia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Sfax
Postoperative Pain
Dexamethasone for Post Cesarean Delivery Analgesia
The purpose of this study is to assess the effectiveness intravenous (IV) dexamethasone when used as part of a multimodal regimen to manage post cesarean delivery pain.
- Trial name
- NCT01868633
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Iowa
Hypotension Drug-Induced, Cesarean Section Complications
Spinal Anesthesia in Caesarean Section
Spinal anesthesia is a safe technique, widely used and tested in the gynecological field, so as to be considered the first choice technique in cesarean section, which allows to quickly obtain a valid sensor and motor block.
- Conditions
- Hypotension Drug-Induced, Cesarean Section Complications, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use, Bradycardia
- Trial name
- NCT03743870
- Testing
- Levobupivacaine, Bupivacaine
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Azienda Ospedaliera, Universitaria Policlinico Vittorio Emanuele
Pre- and Postoperative Analgesia, Spinal Anesthesia
Randomized Study of Spinal Anesthesia Compared With Traditional Epidural Anesthesia Concerning Peroperative and Postoperative Pain After Open Nephrectomy in Patients With Renal Cell Carcinoma
The study aim to study whether spinal anesthesia (using: bupivacain, morfin och klonidin) can be better than epidural anesthesia during and after open surgery for renal cell carcinoma.
- Conditions
- Pre- and Postoperative Analgesia, Spinal Anesthesia, Renal Cell Carcinoma
- Trial name
- ASA (NCT02030717)
- Testing
- klonidin, epidural anesthesia
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Umeå University
Hypotension During Cesarean Delivery, Postoperative Nausea and Vomiting (PONV)
Dexamethasone to Prevent Side Effects of Spinal Anesthesia in Cesarean Delivery
The goal of this clinical trial is to evaluate the effectiveness of intravenous dexamethasone in preventing adverse effects of spinal anesthesia and prolonging postoperative analgesia in parturients undergoing elective cesarean…
- Conditions
- Hypotension During Cesarean Delivery, Postoperative Nausea and Vomiting (PONV), Pain, Postoperative
- Trial name
- NCT07615595
- Testing
- Dexamethasone
- Where
- Vietnam
- Volunteers
- 176 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Anterior Ilıac Block, Hernia Surgery
Effect of Anterior Iliac Block on Postoperative Analgesia and Patient Satisfaction in Inguinal Hernia Repair Surgery
Inguinal hernia repair is one of the most commonly performed surgical procedures worldwide and presents challenges in anesthesia selection and postoperative pain management.
- Conditions
- Anterior Ilıac Block, Hernia Surgery, Spinal Anesthesia
- Trial name
- NCT07533383
- Testing
- Anterior Iliac Block, Control Group (A):
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital