Clinical trials: Spinal Block
Cardiac Arrythmias
Carbetocin on Myocardial Repolarization Dynamics in Obstetrics Study
Relationship between carbetocin dose on transmural dispersion of repolarization (TDR).
- Trial name
- CaRDIO (NCT03716076)
- Testing
- Carbetocin
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Pain
Effect of Shotblocker on Procedure-related Pain, Satisfaction and Comfort in Patients Receiving Spinal Anesthesia
Although spinal anesthesia, which is increasingly common today, is a fast and reliable method, many patients are afraid of this procedure due to their fear of needles.
- Trial name
- NCT06163027
- Testing
- Shotblocker, Shotblocker(Plasebo)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Conscious Sedation Under Spinal Anesthesia
The Optimal Effect Site Concentration of Propofol for Conscious Sedation in Elderly Male Patients Undergoing Urologic Surgery Under Spinal Anesthesia With or Without Intrathecal Fentanyl
Since intrathecal fentanyl is known to sedation effect, intrathecal fentanyl will result in lowering propofol requirement for conscious sedation under spinal anesthesia.
- Trial name
- NCT01232270
- Testing
- propofol
- Where
- South Korea
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Anesthesia, Spinal
Failure Rate in Spinal Blocks and Determination of Related Factors
Investigators aimed to determine the rates of unsuccessful spinal anesthesia, to determine the factors related to failure and to determine the measures that may be taken to reduce this problem.
- Trial name
- NCT03959644
- Where
- Turkey (Türkiye)
- Volunteers
- 1,431 people, healthy volunteers welcome
- Sponsor
- Bozyaka Training and Research Hospital
Hypotension
Colloid Preload Versus Crystalloid Co-load in Cesarean Section Under Spinal Anesthesia
Comparison between colloid preload and crystalloid co-load in cesarean section under spinal anesthesia. 1. The primary outcome was the incidence of hypotension 2.
- Trial name
- CPvsCC (NCT03107598)
- Testing
- colloid preload
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- University Hospital, Mahdia
Anxiety, Hypotension
Impact of Music on Satisfaction, Anxiety, and Hemodynamics During Spinal Anesthesia for Cesarean Delivery
The aim of this study is to evaluate the effect of perioperative music on maternal anxiety, hemodynamic response to spinal anesthesia, postoperative pain medication requirement, and overall maternal satisfaction.
- Trial name
- NCT02732964
- Testing
- Pandora Music, Mozart Music
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Hyperoxia, Hypoxia
The Association Between Sensory Block Level, Oxygen Therapy, and ORi in Varicose Vein Patients Undergoing Spinal Anesthesia (ORi: Oxygen Reserve Index)
The assessment of peripheral capillary oxygen saturation (SpO2) by pulse oximetry has become standard in perioperative care for the detection of hypoxaemia.
- Trial name
- ORi (NCT06566690)
- Testing
- Addition of ORi monitoring to SpO2 monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Hypotension, Nausea
Ideal Dose of Phenylephrine to Treat Low Blood Pressure During Cesarean Section
The purpose of this study is to determine the minimum effective bolus dose of phenylephrine to prevent post-spinal hypotension in Cesarean section in 95 % of our patients.
- Trial name
- NCT00379691
- Testing
- phenylephrine
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Pregnancy, Cesarean Section
RCT of Epinephrine (None, 100mcg, and 200mcg) in a Hyperbaric Bupivacaine, Fentanyl and Morphine Spinal in C-sections.
This is a prospective, randomized, double blind study of 75 patients (n=25 for each group) in which epinephrine (100mcg or 200mcg) or normal saline vehicle is added to intrathecal hyperbaric bupivacaine (0.75% bupivacaine…
- Trial name
- NCT03335293
- Testing
- 100 mcg Epinephrine, normal saline, 200 mcg Epinephrine
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Comparing 2 Techniques of iv Oxytocin Causing Hemodynamic Changes
Compare Hemodynamic Effect of Oxytocin Bolus and Infusion During Cesarean Section Under Spinal Anesthesia
Oxytocin is routinely used during a cesarean section to promote uterine contraction and prevent postpartum hemorrhage. It is typically administered immediately after delivery of the baby, either as a slow intravenous bolus…
- Trial name
- NCT07687355
- Testing
- Oxytocin bolus
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Hayatabad Medical Complex
Pulmonary Edema
a Comparison Between the Effects of Crystalloids and Colloids on Lung Ultrasound
This study is designed to compare the effect of crystalloids and colloids on lung ultrasound score in preeclapmtic pregnant cases undergoing spinal anesthesia for caesarean section Objectives: To identify ideal fluid in order to…
- Trial name
- NCT05505708
- Testing
- hydroxyethyl starch in sodium chloride injection Brand Name: Voluven, saline solution
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Postoperative Pain, Pain
Comparison of Analgesic Efficacy of Intrathecal Bupivacaine Versus Bupivacaine Plus Dexmedetomidine in Patients Undergoing Orthopedic Surgeries.
Clinical Trial Overview: Intrathecal Bupivacaine vs. Bupivacaine + Dexmedetomidine Primary Objective Duration of Analgesia:** To compare the mean duration of postoperative pain relief between hyperbaric bupivacaine alone versus…
- Conditions
- Postoperative Pain, Pain, Orthopaedic Surgery, Anesthesia, Spinal
- Trial name
- NCT07866508
- Testing
- Dexmedetomidine plus Hyperbaric Bupivacaine, Hyperbaric bupivacaine % 0.5
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sheikh Khalifa Bin Zayed Al Nahyan Combined Military Hospital Muzaffarabad
Pain Measurement, Visual Analog Pain Scale
The Analgesic Effect of Intrathecal Hydromorphone Injection on Spinal Anesthesia
The purpose of this study is to evaluate the adequate dose of intrathecal hydromorphone injection for postoperative pain relief after knee arthroscopic surgery.
- Trial name
- NCT01172782
- Testing
- Hydromorphone
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Hemodynamic Instability
Effect of Intravenous Ketamine Infusion for Hemodynamic Stability in Patients Undergoing Caesarean Delivery.
Hypotension is the most frequent side effect of intrathecal anesthesia, with a found incidence of more than 80%. With a frequency of between 40% and 60% in patients undergoing surgery, Perioperative shivering is a serious…
- Trial name
- NCT05865080
- Testing
- Ketamine
- Where
- Egypt
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Spinal Anesthesia Induced Hypotension, Geriatric
Internal Jugular Vein Ultrasound for Predicting Hypotension in Geriatric Patients Undergoing Spinal Anesthesia
Spinal anesthesia-induced hypotension is a common and clinically significant complication in geriatric patients. Accurate preoperative assessment of intravascular volume status may help identify patients at risk.
- Conditions
- Spinal Anesthesia Induced Hypotension, Geriatric, Internal Jugular Vein, Ultrasonography
- Trial name
- IJV-SPINAL (NCT07411313)
- Testing
- Not applicable- observational study
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Post Spinal Anaesthesia Hypotension, Inferior Vena Cava Collapsibility Index
Inferior Vena Cava Collapsibility Index Assessment in Predicting Post Spinal Anaesthesia Hypotension in Patients Undergoing Arthroscopic Knee Surgeries.
The aim of this study was to evaluate the role of inferior vena cava collapsibility index assessment in predicting post spinal anaesthesia hypotension in patients undergoing arthroscopic knee surgeries.
- Trial name
- NCT06767033
- Testing
- Ultrasound Guided Inferior Vena Cava Collapsibility Index Assessment
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Caesarean Section, Pain, Acute
Subarachnoid Block With Ultrasound-Guided Transversalis Fascia Plane Block for Cesarean Section
Postoperative pain management is critical for the fulfillment of the maternal duties. The transversalis fascia plane (TFP) block provides adequate postoperative analgesia in the T12 and L1 dermatomes.
- Trial name
- NCT04172727
- Testing
- Bupivacaine Hcl 0.25% Inj, saline 0.9%
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Cesarean Section, Preoperative Anxiety
Effects of Sedation on Spinal Anesthesia-induced Maternal Hypotension
Background: This study was designed to investigate the effect of sedation on the occurrence of maternal hypotension in preoperatively anxious parturients undergoing urgent category-1 Cesarean section (C/S) under spinal…
- Conditions
- Cesarean Section, Preoperative Anxiety, Spinal Anesthesia, Sedation
- Trial name
- NCT02732197
- Testing
- Sedation, No sedation
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Van Training and Research Hospital
Prevention of Shivering With Spinal Anaesthesia
Could Ephedrine Replace Dexmedetomidine Fordexmedetomidine Prevention of Shivering in Women Undergoing Cesarean Section Under Spinal Anaesthesia
Could ephedrine replace dexamedetomidine for prevention of shivering in women undergoing Cesarean section Under spinal anaesthesia
- Trial name
- NCT06233032
- Testing
- Ephedrine, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cesarean Section Complications
Intravenous Dexmedetomidine in Cesarean Section Under Spinal Anesthesia
The present study hypothesized that intravenous dexmedetomidine use during spinal anesthesia for cesarean section has a beneficial influence on hemodynamic stability and epigastric pain together with satisfactory analgesic…
- Trial name
- NCT04358367
- Testing
- Dexmedetomidine Injectable Product, Saline
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Egyptian Biomedical Research Network