Clinical trials: Spinal Canal Stenosis
Lumbar Spinal Stenosis, Spondylolisthesis
Minuteman Spinal Fusion Implant Versus Surgical Decompression for Lumbar Spinal Stenosis
Lumbar spinal stenosis (LSS), is a common disorder of narrowing of the spinal canal in the lower part of the back. This causes discomfort in the legs when standing or walking because of pressure on the spinal nerves.There are…
- Conditions
- Lumbar Spinal Stenosis, Spondylolisthesis, Degenerative Disc Disease
- Trial name
- NCT01455805
- Testing
- Minuteman Fusion Implant, surgical decompression
- Where
- 4 sites in United Kingdom
- Volunteers
- 48 people
- Sponsor
- Spinal Simplicity LLC
Degenerative Disk Disease, Spinal Stenosis of Lumbar Region
Performance of Inductigraft in Spinal Fusion
This is an open-label non-randomised, prospective, post market study to evaluate the performance of Inductigraft (osteoinductive synthetic bone graft) in patients receiving posterolateral lumbar spine fusion through assessment of…
- Trial name
- APOLLO (NCT01452022)
- Testing
- Inductigraft
- Where
- 15 sites in Germany, Hungary and 3 more
- Volunteers
- 125 people
- Sponsor
- Baxter Healthcare Corporation
Lumbar Spinal Stenosis
Physical Therapy Treatments, Including Neural Mobilization and Hip/Back Stretches for People Between 50-89 With Lumbar Spinal Stenosis and Leg Pain Provoked by Walking
Aging of the back is common in the older people and can result in difficulties standing and walking. Conservative treatment is recommended before considering surgery.
- Trial name
- NCT03368638
- Testing
- Physical therapy intervention
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Texas Tech University Health Sciences Center
Spinal Anaesthesia, Magnetic Resonance Imaging (MRI)
MRI-Based Estimation of Lumbar CSF Volume and Its Clinical Impact on Spinal Anaesthesia
This prospective observational study aims to investigate the clinical impact of lumbar cerebrospinal fluid (CSF) volume on spinal anesthesia characteristics.
- Conditions
- Spinal Anaesthesia, Magnetic Resonance Imaging (MRI), Lumbosacral Spinal Stenosis, Anaesthesia
- Trial name
- NCT07333703
- Testing
- Distribution of spinal anesthetic agent
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Samsun University
Lumbar Spinal Stenosis
Patients With Lumbar Spinal Stenosis With Balance Disorder
It is seen that patients with Lumbar Spinal Stenosis often experience balance problems. Although the relationship between muscle thickness and balance has been explained, there are insufficient studies investigating the…
- Trial name
- NCT06079580
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Lumbar Spinal Stenosis
Hybrid vs Fluoroscopy-Guided Interlaminar Epidural Injection in Lumbar Spinal Stenosis
Lumbar spinal stenosis is a common degenerative condition that can cause chronic low back and leg pain, especially during walking or standing.
- Trial name
- NCT07612982
- Testing
- Ultrasound-guided lumbar interlaminar epidural steroid injection with fluoroscopic confirmation, Fluoroscopy-guided lumbar interlaminar epidural steroid injection
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Marmara University
Spondylolisthesis, Spinal Stenosis
Spine Patient Outcomes Research Trial (SPORT): Degenerative Spondylolisthesis With Spinal Stenosis
This study tests the effectiveness of different treatments for the three most commonly diagnosed conditions of the lower backbone (lumbar spine).
- Conditions
- Spondylolisthesis, Spinal Stenosis, Low Back Pain
- Trial name
- SPORT (NCT00000409)
- Testing
- Decompressive laminectomy, Non-surgical treatments, Fusion--Instrumented
- Where
- 13 sites in United States
- Volunteers
- 304 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Spinal Stenosis
Stabilimax Investigational Device Exemption (IDE) Clinical Investigation Patient Followup Study
The intent of this study is to complete the collection of clinical data on subjects enrolled in the Stabilimax Dynamic Spine Stabilization IDE clinical trial (#G060214) sponsored by the now defunct Applied Spine Technologies Inc…
- Trial name
- NCT01485289
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Rachiotek LLC
Lumbar Spinal Stenosis
Study Comparing 3 Different Treatments for Arthritis of the Lower Back (Lumbar Spinal Stenosis)
BACKGROUND: Lumbar spinal stenosis - known by patients as "arthritis of the spine" - is a condition that is very common; found in about 30% of older adults.
- Trial name
- NCT01943435
- Testing
- NSAIDs; adjunctive analgesics; adjunctive anti-depressants, Lumbar epidural injection, Joint Mobilizations (spine, sacroiliac, hip)
- Where
- United States
- Volunteers
- 259 people
- Sponsor
- Michael Schneider, DC, PhD
Adult Spinal Deformity, Degenerative Scoliosis
Gait and Paraspinal sEMG in Degenerative Spinal Diseases
This cross-sectional observational study aims to quantitatively compare three-dimensional gait parameters, surface electromyography (EMG) patterns, and radiological parameters among patients with different degenerative spinal…
- Conditions
- Adult Spinal Deformity, Degenerative Scoliosis, Sagittal Deformity, Sagittal Imbalance
- Trial name
- TDGKSEPDSD (NCT07309926)
- Testing
- Gait analysis and surface electromyography analysis
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Degenerative Disc Disease, Spinal Stenosis
Assessment of nanOss Bioactive 3D in the Posterolateral Spine
Spine fusion is one of the most common procedures performed in spinal surgery. Several surgical techniques can achieve a solid union, but the intertransverse posterolateral fusion (PLF) is the most widely used.
- Conditions
- Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis
- Trial name
- NCT01829997
- Testing
- nanOss Bioactive 3D BVF
- Where
- 4 sites in United States
- Volunteers
- 22 people
- Sponsor
- Pioneer Surgical Technology, Inc.
Spinal Stenosis Lumbar, Spinal Canal Stenosis
Degenerative Lumbar Stenosis Conservative Treatment
The trial aims to compare the effectiveness of three methods of conservative treatment of degenerative lumbar spine stenosis (DLSS): GOLDIC autologous serum epidural injections, steroid epidural injections and manual therapy.
- Trial name
- GOLDSTEN (NCT04492774)
- Testing
- Goldic serum, Steroid injections, Manual therapy
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Sutherland Medical Center
Spinal Stenosis Lumbar
Lumbar Proprioception in Patients With Lumbar Spinal Stenosis
The primary aim of this study was to compare spinal proprioception in patients with Lumbal Spinal Stenosis (LSS) (with or without surgery) and healthy controls.
- Trial name
- NCT05548608
- Testing
- Reposition error (RE), pain at target positions of RE and flexibility of the TLF were assesed with iphone tiltmeter app, VAS and goniometric platform, respectively.
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Lumbar Spinal Stenosis
Targeted Nutritional Supplement After Lumbar Spine Surgery: A Randomized, Placebo-Controlled, Double-Blind Trial
The goal of this clinical trial is to prospectively evaluate the effects of essential amino acid (EAA) supplementation on the volume and structure of the muscles surrounding the spine (paraspinal musculature).
- Trial name
- NCT06579391
- Testing
- Essential amino acids, Alanine
- Where
- United States
- Sponsor
- University of California, Irvine
Spinal Stenosis, Low Back Pain
Effects of Maitland and Mulligan Spinal Mobilizations Along With Canal Enlargement Exercises in Lumbar Spinal Stenosis
This randomised controlled trial will evaluate the comparative effects of Maitland versus Mulligan spinal mobilization techniques, when combined with canal enlargement exercises, in patients with lumbar spinal stenosis (LSS).
- Trial name
- NCT07080073
- Testing
- Maitland Mobilization Group, Mulligan Mobilization Group
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Spine Fusion, Spine Tumor
Effect of Ketamine on Intraoperative Motor Evoked Potentials
The goal of this clinical trial is to learn about the effect of ketamine on intraoperative motor evoked potentials in adult patients undergoing thoracolumbar spinal fusions. Participants will undergo a standard anesthetic.
- Conditions
- Spine Fusion, Spine Tumor, Spinal Stenosis
- Trial name
- NCT06140927
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Lumbar Spinal Stenosis
Preoperative Rehabilitation for Patients Undergoing Surgery for Lumbar Spinal Stenosis
The purpose of the present study is to evaluate the effectiveness of a prehabilitation program on the recovery of patients undergoing a minimally invasive surgery for degenerative lumbar spinal stenosis.
- Trial name
- NCT02258672
- Testing
- Prehabilitation program
- Where
- Canada
- Volunteers
- 68 people
- Sponsor
- Université du Québec à Trois-Rivières
Lumbar Disc Herniation
Comparative Study Between UBE and PETD for the Treatment of Lumbar Spinal Canal Stenosis
OBJECTIVE Both unilateral biportal endoscopy technique(UBE) and percutaneous endoscopic transforaminal discectomy(PETD) are minimally invasive and effective surgical procedures for lumbar spinal stenosis.The object of this…
- Trial name
- NCT05033457
- Testing
- unilateral biportal endoscopy technique or percutaneous endoscopic transforaminal discectomy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shaanxi Provincial People's Hospital
Radiculopathy, Spinal Stenosis
Steroid Injections Given at the "Level of MRI Pathology" Versus at the "Level of Clinical Symptoms" to See if One is More Effective Than the Other.
Patients are being asked to participate in a research study because the patients are being treated for low back pain and the patients have decided to have an epidural steroid injection.
- Conditions
- Radiculopathy, Spinal Stenosis, Intervertebral Disc Displacement
- Trial name
- NCT02196883
- Testing
- Transforaminal Epidural Steroid Injection
- Where
- United States
- Sponsor
- State University of New York - Upstate Medical University
Lumbar Spinal Stenosis With Bilateral Lower Extremity Radiculopathy
Effect of Skin Stretching on Pain Reduction During Local Anesthetic Injections: A Randomized Clinical Study
The purpose of this study is to investigate the potential analgesic effect of skin stretching during local anesthetic injection in patients with chronic lumbar pain and bilateral lower extremity radiculopathy undergoing selective…
- Trial name
- NCT06976580
- Testing
- conventional local anesthetic injection, skin stetching technique for local anesthetic injection
- Where
- South Korea
- Volunteers
- 104 people
- Sponsor
- Yonsei University