Clinical trials: Spinal Canal Stenosis
Spinal Stenosis
Effectiveness of a 6-week Specific Rehabilitation Program on Walking Capacity in Patients With Lumbar Spinal Stenosis
The aim of this study is to determine the effectiveness of a 6-week specific rehabilitation program combining education and exercises on walking capacity in patients with LSS causing NC.
- Trial name
- NCT05513326
- Testing
- Exercises and education, Education alone
- Where
- Canada
- Volunteers
- 51 people
- Sponsor
- Université du Québec à Trois-Rivières
Spinal Stenosis, Low Back Pain
Total Facet Arthroplasty System®(TFAS®) Clinical Trial
The Archus Total Facet Arthroplasty System® (TFAS®) is a non-fusion spinal implant indicated for treatment of patients with moderate to severe spinal stenosis. TFAS® replaces the diseased facets following surgical removal.
- Conditions
- Spinal Stenosis, Low Back Pain, Spondylolisthesis, Lumbar Spinal Stenosis
- Trial name
- NCT00418197
- Testing
- Total Facet Arthroplasty System® (TFAS®)
- Volunteers
- 450 people
- Sponsor
- Archus Orthopedics, Inc.
Cervical Spinal Stenosis, Cervical Spinal Cord Injury
Study of Individualized, Precise and Standardized Cervical Open-door Surgery for Cervical Spinal Stenosis
To evaluate the safety and effectiveness of individualized, precise and standardized open-door posterior cervical surgery through a single-center, exploratory clinical study, so as to provide a more reliable basis for the…
- Conditions
- Cervical Spinal Stenosis, Cervical Spinal Cord Injury, Individuation, Standardization
- Trial name
- NCT05786313
- Testing
- Centerpiece titanium plate
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Xijing Hospital
Spinal Stenosis, Lumbosacral Region
Stability Comparison of TIVA and Sevoflurane in Prone Spinal Surgery(TIVA:Total Intravenous Anesthesia)
Key Points: 1. Objective: o To compare the effects of Total Intravenous Anesthesia (TIVA) and sevoflurane anesthesia on respiratory mechanics, hemodynamic parameters, and neuromonitoring during prone position spinal surgeries. 2.
- Trial name
- TIVA (NCT06558695)
- Testing
- Sevoflurane, TIVA
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Lumbar Spinal Stenosis
Comparision of Endoscopic Discectomy and Microdiscectomy for the Treatment of Lumbar Spinal Stenosis
The purpose of this study is to conduct a multicenter comparison of the clinical efficacy of Endo-Surgi Plus endoscopic technique, UBE endoscopic technique, and microdiscectomy technique in the treatment of lumbar spinal…
- Trial name
- NCT06719037
- Testing
- Endo-Surgi Plus endoscopic surgery, Unilateral biportal endoscopic surgery, Microdiscectomy
- Where
- China
- Volunteers
- 324 people
- Sponsor
- Qilu Hospital of Shandong University
Parkinson Disease, Dystonia
Spine MRI in Patients With Deep Brain Stimulation (DBS)
Magnetic resonance imaging (MRI) of patients implanted with deep brain stimulation (DBS) is under strict safety guidelines. Depending on the body part being imaged, the safety may vary.
- Conditions
- Parkinson Disease, Dystonia, Depression, Spinal Stenosis
- Trial name
- NCT03753945
- Testing
- MRI of the spine
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- University Health Network, Toronto
Spondylolisthesis, Degenerative Lumbar Disc Disease
Spine Research With Roentgen Stereophotogrammetric Analysis
The purpose of this study is to gather information on the effectiveness of a new spine implant for patients who require spinal fusion surgery.
- Conditions
- Spondylolisthesis, Degenerative Lumbar Disc Disease, Spinal Stenosis
- Trial name
- SpineRSA (NCT00493558)
- Testing
- Trabecular Metal Intervertebral Cage with RSA beads
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- Nova Scotia Health Authority
Degenerative Spondylolisthesis or Retrolisthesis, Spinal Stenosis
A Clinical Study of the Dynesys(R) Spinal System
This non-inferiority study will compare the clinical outcomes of subjects implanted with the Dynesys Spinal System versus the clinical outcomes of subjects implanted with an instrumented posterior lateral spinal fusion.
- Conditions
- Degenerative Spondylolisthesis or Retrolisthesis, Spinal Stenosis, Stenosing Lesion.
- Trial name
- NCT00759057
- Testing
- Posterior Pedicle Screw System
- Where
- 26 sites in United States
- Volunteers
- 399 people
- Sponsor
- Zimmer Biomet
Lumbar Spinal Stenosis
The STEPS - Totalis™ Trial
The purpose of this study is to determine safety and effectiveness, as measured by changes in pain, disability, patient satisfaction, and claudicatory symptoms, at 6 months following treatment with the Totalis™ Direct…
- Trial name
- NCT02079038
- Testing
- Totalis, Comparator Surgical Procedure
- Where
- 19 sites in United States
- Volunteers
- 180 people
- Sponsor
- VertiFlex, Incorporated
Lumbar Central Spinal Stenosis, Restless Legs Syndrome
Epidural Steroid Injection for Restless Legs Symptoms in Lumbar Stenosis
Lumbar central spinal stenosis (LCSS) is a common degenerative spinal disorder characterized by narrowing of the spinal canal, resulting in chronic low back pain, leg pain, and neurogenic claudication.
- Trial name
- NCT07637643
- Testing
- Lumbar Interlaminar Epidural Steroid Injection
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Saglik Bilimleri Universitesi
Lumbar Spinal Stenosis, Lumbar Spondylolisthesis
Effectiveness and Safety of Korean Medicine for Low Back Pain or Sciatica Due to Lumbar Stenosis/Spondylolisthesis
A prospective observational study investigating the effectiveness and safety of integrative Korean medicine treatment in lumbar stenosis or spondylolisthesis patients with low back pain or sciatica at 3 locations of Jaseng…
- Conditions
- Lumbar Spinal Stenosis, Lumbar Spondylolisthesis, Low Back Pain, Sciatica
- Trial name
- NCT03879447
- Testing
- Herbal medicine, Chuna manual medicine, Bee venom pharmacopuncture
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- Jaseng Medical Foundation
Degenerative Disc Disease, Spinal Stenosis
Assessment of nanOss Bioactive 3D in the Posterolateral Spine
Spine fusion is one of the most common procedures performed in spinal surgery. Several surgical techniques can achieve a solid union, but the intertransverse posterolateral fusion (PLF) is the most widely used.
- Conditions
- Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis
- Trial name
- NCT01829997
- Testing
- nanOss Bioactive 3D BVF
- Where
- 4 sites in United States
- Volunteers
- 22 people
- Sponsor
- Pioneer Surgical Technology, Inc.
Spinal Stenosis
The Impact of Epidural Fat Resection on Postoperative Outcomes in Posterior Surgery of Lumbar Spine
Posterior lumbar epidural fat commonly had been considered a simple space-filling tissue. Anatomic studies on posterior epidural space and its contents are few, including semifluid property.
- Trial name
- NCT02127008
- Testing
- Resection of epidural fat, No resection of epidural fat
- Where
- South Korea
- Volunteers
- 185 people
- Sponsor
- Seoul National University Hospital
Multilevel Cervical Spinal Stenosis, Single Brachial Radiculopathy
Head-neck Coordination Analysis After Minimally Invasive Surgery in the Dorsal Cervical Spine
To proof patients' benefit of minimally invasive surgery in the dorsal cervical spine an apparatus to examine head-neck-coordination was constructed.
- Trial name
- MISDCS (NCT01988259)
- Testing
- Bilateral approach for Laminoplasty, Unilateral approach for laminoplasty, Subperiosteal approach for foraminotomy
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Schoen Klinik Hamburg Eilbek
Lumbar Spinal Stenosis
MiDAS II (Mild® Decompression Alternative to Open Surgery): Vertos Mild Patient Evaluation Study
This is a multi-center, prospective, patient outcomes assessment of Minimally Invasive Lumbar Decompression with the Mild® devices in patients with symptomatic central canal spinal stenosis.
- Trial name
- NCT01082159
- Testing
- lumbar decompression
- Where
- 8 sites in United States
- Volunteers
- 55 people
- Sponsor
- Vertos Medical, Inc.
Spinal Stenosis
Physical Therapy vs Surgical Decompression for Lumbar Spinal Stenosis
This is a randomized controlled multicenter trail comparing physical therapy to surgical decompression in patients with lumbar spinal stenosis.
- Trial name
- PTvsSD (NCT04552145)
- Testing
- surgery, Physiotherapy
- Where
- 3 sites in Norway
- Volunteers
- 232 people
- Sponsor
- Norwegian University of Science and Technology
Spinal Stenosis Lumbar, Lumbar Disc Herniation
Cortical Bone Trajectory Screws vs. Traditional Pedicle Screws Fixation
Transforaminal lumbar interbody fusion (TLIF) had been favorable for effectively decrease pain and disability in specific spinal disorders; however, there has been concern regarding pedicle screw placement during TLIF surgery.
- Conditions
- Spinal Stenosis Lumbar, Lumbar Disc Herniation, Intervertebral Disc Degeneration
- Trial name
- NCT03105167
- Testing
- cortical bone trajectory screws, pedicle screws
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Lumbosacral Spinal Stenosis
Irrigation Endoscopic Decompressive Laminotomy
The classic laminectomy for surgical treatment of spinal stenosis has considerable morbidity .This is further magnified by the disease being more common in elderly with associated medical comorbidities and being usually global…
- Trial name
- NCT01991912
- Testing
- open lumbar decompression
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Lumbar Spinal Stenosis
Effectiveness and Safety of Korean Medicine for Lumbar Stenosis Patients With Sciatica
A prospective study investigating the effectiveness and safety in lumbar stenosis patients receiving integrative Korean medicine treatment at 3 locations of Jaseng Hospital of Korean Medicine through assessment of pain…
- Trial name
- NCT02975011
- Testing
- Herbal medicine, Chuna manipulation, Bee venom pharmacopuncture
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Jaseng Medical Foundation
Lumbar Spinal Stenosis
The iO-Flex® Study: Evaluation of the Baxano iO-Flex® System for Decompressive Lumbar Surgery
The purpose of this study is to evaluate the clinical performance of the iO-Flex® System in reducing pain and symptom severity in patients with one or two level lumbar spinal stenosis that requires surgery.
- Trial name
- NCT01067014
- Testing
- Baxano iO-Flex® System
- Where
- 18 sites in United States
- Volunteers
- 75 people
- Sponsor
- Baxano Surgical, Inc.