Clinical trials: Spinal Cord
Erectile Dysfunction, Spinal Cord Injuries
Efficacy and Safety of Tadalafil in Subjects With Erectile Dysfunction Caused by Spinal Cord Injury
This is a study of the efficacy and safety of on-demand dosing of tadalafil or placebo administered for 12 weeks to men with erectile dysfunction caused by spinal cord injury.
- Trial name
- NCT00421083
- Testing
- tadalafil
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Eli Lilly and Company
Central Cord Injury Syndrome, Central Spinal Cord Syndrome
Intermittent Positive-Pressure Breathing Effects in Patients With High Spinal Cord Injury
Background: To determine whether intermittent positive-pressure breathing (IPPB) improved lung compliance, work of breathing, and respiratory function in patients with recent high spinal cord injury (SCI).
- Trial name
- NCT00476866
- Testing
- intermittent positive-pressure breathing (IPPB)
- Where
- France
- Volunteers
- 14 people
- Sponsor
- University of Versailles
Spinal Cord Compression From Neoplasm Metastasis
SuperDEX Trial (Comparison of Two Doses of Dexamethasone for Malignant Spinal Cord Compression Treated by Radiotherapy).
The study aimed to pilot the viability of a full scale randomised comparison of 2 steroid doses in malignant spinal cord compression, to establish safety of high dose dexamethasone in this setting in Australia, to test web…
- Trial name
- NCT00193869
- Testing
- Dexamethasone
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- Trans Tasman Radiation Oncology Group
Urinary Tract Infection(UTI)
E. Coli for Prevention of Catheter UTI in SCI Patients
The overall goal of this project is to develop a new approach for the prevention of urinary tract infection (UTI) in persons who rely on indwelling catheters for bladder drainage.
- Trial name
- NCT00458471
- Testing
- Insertion of a urinary catheter coated with benign E. coli
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Tetraplegia, Spinal Cord Injury
Abdominal Functional Electrical Stimulation in Tetraplegia
People with high spinal lesions are at risk of respiratory complications because they have partial or complete paralysis of breathing muscles.
- Trial name
- NCT00202631
- Testing
- Surface Functional Electrical Stimulation
- Where
- United Kingdom
- Volunteers
- 4 people
- Sponsor
- South Glasgow University Hospitals NHS Trust
Female Sexual Dysfunction, Multiple Sclerosis
Effects of Spinal Cord Injury on Female Sexual Response
The long term aims of this project are to 1) Understand the effect of varying degrees and levels of SCI and dysfunction(SCI/D)on females sexual response: 2) Identify the specific neuronal pathways involved in female sexual…
- Conditions
- Female Sexual Dysfunction, Multiple Sclerosis, Spinal Cord Injury
- Trial name
- NCT00142714
- Testing
- Sympathetic manipulation on sexual arousal in women
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Spinal Cord Injury
Paraplegic Cycling: Improving Health After Spinal Cord Injury
Surface electrical stimulation has for many years been widely used to retrain paralysed muscle and achieve the functions of standing and stepping.
- Trial name
- NCT00204100
- Testing
- Surface Functional Electrical Stimulation
- Where
- 2 sites in United Kingdom
- Volunteers
- 5 people
- Sponsor
- University of Glasgow
Spinal Cord Injury
Exercise Testing During Treadmill Gait in Incomplete Spinal Cord Injury
Treadmill therapy has the potential to improve the physical fitness and voluntary function of incomplete-lesion spinal cord injured (SCI) patients.
- Trial name
- NCT00204126
- Testing
- Treadmill with partial body weight support, Surface Functional Electrical Stimulation
- Where
- 2 sites in United Kingdom
- Volunteers
- 4 people
- Sponsor
- University of Glasgow
Myelopathy, AIDS-Myelopathy
Treatment of AIDS Vacuolar Myelopathy With Methionine
The purpose of this study is to determine whether methionine, an amino acid present in low doses in the normal diet, can improve myelopathy or stop its progression.
- Conditions
- Myelopathy, AIDS-Myelopathy, AIDS Vacuolar Myelopathy
- Trial name
- NCT00032695
- Testing
- methionine
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Constipation, Fecal Incontinence
Treatment of Fecal Incontinence and Constipation in Patients With Spinal Cord Injury
The study aims to compare a newly developed system for transanal colonic irrigation (Peristeen Anal Irrigation) with a bowel management regime that does not include irrigation in a prospective, randomized trial in spinal cord…
- Conditions
- Constipation, Fecal Incontinence, Spinal Cord Injury
- Trial name
- NCT00286520
- Testing
- Transanal irrigation with Peristeen Anal Irrigation
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Aarhus
Cerebrovascular Accident, Spinal Cord Injury
Measurement of Pulse Wave Velocity in Spinal Cord Injury and Stroke Patients
According to the theory of wave transmission, the speed of wave transmission is dependent on the nature of the transmission medium, which is the vessel wall for pulse wave transmission.
- Trial name
- NCT00172289
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Spinal Cord Injury
Changes of Parameters of Transcranial Magnetic Stimulation in Patients With Spinal Cord Injury
CNS reorganization is evidenced in patients with CNS lesion, no exception to the patients with spinal cord injury. The paraplegics have to increase their loading of upper extremities to compesate the lost function of lower…
- Trial name
- NCT00228085
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Spinal Cord Injury
Development of an Instrumental Activities of Daily Living Scale
This study is to develop an IADL Scale for patients with SCI (IADL-SCI) and examine its psychometric properties in three years.
- Trial name
- NCT00173784
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Scoliosis, Spinal Cord Injury
Effects of Lateral Trunk Support on Spinal Alignment in Spinal Cord Injured Persons
The effects of lateral trunk supports (LTS) in special seating on the spinal alignment of 17 spinal cord injured (SCI) subjects with scoliosis were studied using bi-planar radiographs.
- Trial name
- NCT00154505
- Testing
- Lateral trunk support of wheelchair seating
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Spinal Cord Injury., Osteoporosis.
Effectiveness of Vibration and Standing Versus Standing Alone for the Treatment of Osteoporosis for People With Spinal Cord Injury.
The purpose of this study is to find out if standing and/or standing with vibration works for the treatment of osteoporosis for people with a spinal cord injury.
- Trial name
- NCT00150683
- Testing
- vibration and passive standing versus passive standing alone
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Toronto Rehabilitation Institute
Spinal Cord Injury
Phase II Randomized Pilot Study of Body Weight Support and Treadmill Training for Chronic Thoracic Spinal Cord Injury
OBJECTIVES: I. Assess the ability of patients with and without sensorimotor loss below the thoracic spinal cord injury to execute coordinated whole-limb synergies sufficient for walking with full or partial weight support. II.
- Trial name
- NCT00004812
- Testing
- Exercise
- Volunteers
- 26 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Spinal Cord Injuries
Improving Gait in Patients With Spinal Cord Injuries
This study is part of a larger clinical trial that examines the potential of a 12-week treadmill-training program to improve walking in patients with spinal cord injuries (SCIs).
- Trial name
- NCT00060983
- Testing
- Body weight supported locomotor training, Functional electrical stimulation
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Spinal Cord Injury
Treadmill Training With Body Weight Support in Patients With Spinal Cord Injury
Body weight support (BWS) treadmill training uses an overhead harness to give partial support to patients walking on a treadmill.
- Trial name
- NCT00061295
- Testing
- Body weight support treadmill training
- Where
- United States
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)