Clinical trials: Spinal Cord Injuries, Incomplete
Severe Mobility Impairment, Spinal Cord Injuries (Complete and Incomplete)
The Impact of 'Digital Strolling' on Depression and Quality of Life of People With Severe Mobility Impairment
This intervention aims to develop and test the feasibility, acceptability, and preliminary effects of a "Digital Strolling" intervention among people with SMI.
- Conditions
- Severe Mobility Impairment, Spinal Cord Injuries (Complete and Incomplete), Poliomyelitis
- Trial name
- NCT07073144
- Testing
- Virtual walking, Passive observing walking
- Where
- Hong Kong
- Volunteers
- 24 people
- Sponsor
- The Hong Kong Polytechnic University
Incomplete Spinal Cord Injury, Exercise Training
Cardiorespiratory Fitness Training in Patients With Incomplete Spinal Cord Injury
The goal of this exploratory randomized controlled trial is to assess the effect of a personalized training intervention during primary rehabilitation of 6 weeks on cardiorespiratory fitness in individuals with subacute (<6…
- Trial name
- FIT@HOME (NCT06259227)
- Testing
- Cardiorespiratory fitness (CRF) training
- Where
- Netherlands
- Volunteers
- 19 people
- Sponsor
- Sint Maartenskliniek
Spinal Cord Injuries (Complete and Incomplete)
Multisite Transspinal Stimulation for Augmenting Recovery in Spinal Cord Injury
A well-established rehabilitation strategy for improvements of standing and walking ability in persons with spinal cord injury (SCI) is step training on a motorized treadmill with body weight support.
- Trial name
- NCT07204184
- Testing
- Multisite transspinal stimulation at rest, Multisite transspinal stimulation during robotic gait training
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Maria Knikou, PT, MBA, PhD
Incomplete Spinal Cord Injury (SCI)
Transcutaneous Spinal Cord Stimulation (tSCS) During Assisted Cycling Training for Incomplete Spinal Cord Injury.
The goal of this clinical trial is to learn if transcutaneous spinal cord stimulation works to improve lower limb motor function in adults with incomplete spinal cord injury.
- Trial name
- tSCS_SJD_PMI_1 (NCT07445685)
- Testing
- Transcutaneous spinal cord stimulation on the dorsal region between T11 and T12
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Fundació Sant Joan de Déu
Spinal Cord Injury Cervical, Spinal Cord Injuries (Complete and Incomplete)
Development of Optimal Sensory Feedback Strategies to Maximize Function After Tetraplegia
The goal of this clinical trial is to learn more about how stimulating the nerves involved in sensation (either in the limbs or in the brain) can be used to restore sensation in participants who have a spinal cord injury.
- Trial name
- NCT07225582
- Testing
- Brain Computer Interface (BCI) - Functional Electrical Stimulation (FES) system
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Case Western Reserve University
Spinal Cord Disease, Spinal Cord Injuries (Complete and Incomplete)
Spinal Cord Stimulation Combined With Motor Training in Non-Traumatic SCI: A Prospective Interventional Study
Interventional prospective longitudinal on the evaluation of spinal cord stimulation (SCS) assisted by motor rehabilitation training for restoring motor function in patients with non-traumatic spinal cord injury (SCI).
- Trial name
- Neuro-scs-002 (NCT07412808)
- Testing
- Spinal cord stimulation surgery (device implant) and motor rehabilitation
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Albano Luigi
Incomplete Spinal Cord Injury
Myosuit in Incomplete Spinal Cord Injury
The Myosuit is a light-weighted lower extremity soft exosuit which provide assistance during walking. In this study the Myosuit will be tested in the home and community setting in patients with incomplete spinal cord injury.
- Trial name
- NCT05605912
- Testing
- Control, Myosuit
- Where
- Netherlands
- Volunteers
- 34 people
- Sponsor
- Sint Maartenskliniek
Spinal Cord Injury, Chronic, Spinal Cord Injury Cervical
Non-Invasive Interventions for Respiratory Recovery in Chronic Spinal Cord Injury
Spinal cord injuries (SCI) can seriously affect a person's ability to breathe. This happens because the injury can damage the nerves that control the muscles used for breathing.
- Conditions
- Spinal Cord Injury, Chronic, Spinal Cord Injury Cervical, Spinal Cord Injury Thoracic, Incomplete Spinal Cord Injury
- Trial name
- Combinatorial (NCT07135583)
- Testing
- Active Comparator: Single Intervention 1, Active Comparator: Single Intervention 2, Respiratory Resistance Exercise
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Thomas Jefferson University
Stroke, Spinal Cord Injuries (Complete and Incomplete)
Exoskeleton-assisted Neurorehabilitation
Objective assesment of the feasibility of integrating the Ekso Bionics - Ekso NR device into outpatient care Objective assesment of quality of life, functionality and clinical symptomps of patients with stroke, cerebellar ataxia…
- Conditions
- Stroke, Spinal Cord Injuries (Complete and Incomplete), Cerebellar Ataxia, Spastic Paraplegia
- Trial name
- NCT07352085
- Testing
- Gait training with exoskeleton
- Where
- Hungary
- Volunteers
- 5 people
- Sponsor
- Somogy Megyei Kaposi Mór Teaching Hospital
Incomplete Spinal Cord Injury (SCI), ASIA C and D Classification of SCI
Effect of Hybrid Functional Electrical Stimulation and Augmented Reality-Based Gait Training on Gait Parameters Among Incomplete Spinal Cord Injury Patients
The goal of this clinical trial is to determine whether combining Functional Electrical Stimulation (FES) with Augmented Reality (AR)-based gait training can improve walking ability in individuals with incomplete spinal cord…
- Conditions
- Incomplete Spinal Cord Injury (SCI), ASIA C and D Classification of SCI, Gait Dysfunction
- Trial name
- FES AR SCI (NCT07263581)
- Testing
- Functional Electrical Stimulation (FES) and Augmented Reality (AR), Conventional Overground Gait Training (COGT)
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level
Multi-functional Neuroprosthetic System for Restoration of Motor Function in Spinal Cord Injury
This study is to evaluate the use of a fully implanted device for providing hand function, reach, and trunk function to individuals with cervical spinal cord injury. Funding Sources: FDA OOPD NIH NINDS
- Conditions
- Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level, Spinal Cord Injury Cervical, Spinal Cord Injury at C5-C7 Level With Complete Lesion
- Trial name
- NNP-UE+T (NCT02329652)
- Testing
- Networked Neuroprosthetic System for Grasp and Trunk
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Anne Bryden
Stroke, Incomplete Spinal Cord Injury
Comparing the Ceriter Stride One, a Pressure-sensitive Smart Insole, With Gait Parameters Measured on the GRAIL in Neurological Populations
Ceriter Stride-One soles have been available on the market for several years. One of the features of these soles is that they can measure gait parameters while patients walk around in a functional environment.
- Conditions
- Stroke, Incomplete Spinal Cord Injury, Traumatic Brain Injury, Acquired Brain Injury
- Trial name
- NCT07237386
- Testing
- Wearing smart insoles
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Hospital, Ghent
Chronic Incomplete Cervical Spinal Cord Injury (SCI)
Safety and Feasibility of Paired Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) With Upper Limb Rehabilitation in Incomplete Spinal Cord Injury
The purpose of this study is to evaluate the safety and feasibility of transcutaneous auricular Vagus Nerve Stimulation (taVNS) paired with upper-limb rehabilitation in adults with tetraplegia caused by cervical spinal cord…
- Trial name
- NCT06543277
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- The University of Texas Health Science Center, Houston
Incomplete Spinal Cord Injury, Spastic Tetraplegia
Correlation Between Clinical Assessment and Neurophysiological Assessment in Spinal Cord Injury
This study is a cross-sectional study that aims to explore the correlation between clinical assessment and neurophysiological assessment in SCI.
- Conditions
- Incomplete Spinal Cord Injury, Spastic Tetraplegia, Spastic Paraplegia, Spinal Cord Injury
- Trial name
- NCT06680063
- Where
- Thailand
- Volunteers
- 22 people
- Sponsor
- Mahidol University
Incomplete Spinal Cord Injury
Amplify Gait to Improve Locomotor Engagement in Spinal Cord Injury
Spinal cord injury (SCI) affects ~42,000 Veterans. The VA provides the single largest network of SCI care in the nation. The lifetime financial burden of SCI can exceed $3 million. A major cost of SCI is impaired mobility.
- Trial name
- AGILE SCI (NCT04340063)
- Testing
- Gait training performed on a treadmill, Gait training performed in a Movement Amplification Environment
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- VA Office of Research and Development
Stroke, Incomplete Spinal Cord Injury
Comparison of Gait Training Methods in Sub-acute Stroke and Spinal Cord Injury
The purpose of the project is to compare intensity (minutes in target heart rate zone) and steps per session across three gait training modalities, including body-weight supported treadmill training (BWSTT), overground gait…
- Trial name
- NCT06169657
- Testing
- Body-weight-supported treadmill training (BWSTT), EksoNR exoskeleton gait training, Overground gait training
- Where
- United States
- Sponsor
- Shirley Ryan AbilityLab
Incomplete Spinal Cord Injury
Effect of Different Support Systems on Gait
Body weight support systems are commonly used for gait training. A new breed of devices for gait training are soft exosuits. To optimize rehabilitation outcomes, it is important to gain deeper insight in the effect of these…
- Trial name
- NCT06214546
- Testing
- Regular walking, Myosuit, ZeroG
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- Sint Maartenskliniek
Incomplete Spinal Cord Injury
The Effect of Acute Intermittent Hypoxia on Motor Learning
The goal of this study is to examine the effect of repetitive acute intermittent hypoxia on motor learning abilities in able-bodied individuals for subsequent study in individuals with incomplete spinal cord injury.
- Trial name
- NCT05341466
- Testing
- Acute Intermittent Hypoxia
- Where
- 2 sites in United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Spinal Cord Injury, Tetraplegia/Tetraparesis
Evaluation of Usability and Safety of the System Atalante in Patients With High Paraplegia and Tetraplegia
The objective of this clinical trial is to determine whether the Atalante X exoskeleton can be safely utilized by patients with tetraplegia and high paraplegia (at or above T4).
- Conditions
- Spinal Cord Injury, Tetraplegia/Tetraparesis, Paraplegia, Complete, Paraplegia, Incomplete
- Trial name
- QUATRO (NCT06939634)
- Testing
- Hands-free exoskeleton
- Where
- 3 sites in France
- Volunteers
- 35 people
- Sponsor
- Wandercraft
Incomplete Spinal Cord Injury
A Telerehabilitation Program for SCI
This study evaluates a remotely supervised, home-based therapeutic program to improve upper-limb voluntary movement in adults with tetraplegia caused by incomplete spinal cord injury (iSCI).
- Trial name
- NCT04977037
- Testing
- Active tDCS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center, Houston