Clinical trials: Spinal Cord Injuries
Amputations, Peripheral Nerve Injury
Micro-Electrodes Implanted in a Human Nerve
The main objective of the intervention in the study is devise feasibility using high-count microelectrode arrays implanted into peripheral nerves of patients with limb amputations or peripheral nerve injury.
- Conditions
- Amputations, Peripheral Nerve Injury, Spinal Cord Injury
- Trial name
- NCT02034461
- Testing
- Utah Slanted Electrode Array
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Utah
Spinal Cord Injuries (SCI), Upper Limb Function
FES Arm Cycling on Functional Ability and Strength in People With SCI
The goal of this feasibility study is to determine if Functional Electrical Stimulation (FES) arm cycling can be used to improve arm functional ability and arm strength in people with Spinal Cord Injury (SCI).
- Trial name
- NCT07385456
- Testing
- Functional electrical stimulation (FES) arm cycling
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- Glasgow Caledonian University
Spinal Cord Injuries
Transcutaneous Spinal Cord Stimulation and Robotic Therapy
Lumbosacral spinal stimulation activates the neural network involved in the control of locomotion at the spinal level. However, its effects are limited to the production of robust rhythmic patterns of alternating movement, being…
- Trial name
- tscs_Lokomat (NCT05210166)
- Testing
- Active tSCS and Lokomat
- Where
- Spain
- Volunteers
- 27 people
- Sponsor
- University of Castilla-La Mancha
Spinal Cord Injuries
FES Therapy:Restoring Voluntary Grasping Function in Chronic SCI
The main objective of this study is to determine the effectiveness of a new treatment regime that uses electrical stimulation for the improvement of hand function in persons with spinal cord injuries (SCI).
- Trial name
- NCT01208688
- Testing
- FES Therapy, Conventional Occupational Therapy
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Toronto Rehabilitation Institute
Spinal Cord Injuries, Obesity
Spinal Cord Injury Model Systems (SCIMS) - Education Module
The purpose of this study is to find out if receiving education regarding increased risks of cardiometabolic disease helps subjects understand these risks and how these risks participants' health.
- Conditions
- Spinal Cord Injuries, Obesity, Cardiometabolic Syndrome
- Trial name
- NCT06003686
- Testing
- PVA Consumer Guide, WebMD
- Where
- 3 sites in United States
- Volunteers
- 250 people
- Sponsor
- University of Miami
Spinal Cord Injuries
Spinal Cord Stimulation for Autonomic Recovery in Inpatient Rehabilitation After Acute SCI
This study is a randomized, single-blind, two-arm sham-controlled clinical trial to evaluate the safety and efficacy of transcutaneous spinal cord stimulation (tSCS) over the lower thoracic and upper lumbar spinal cord segments…
- Trial name
- NCT06540859
- Testing
- Transcutaneous Spinal Cord Stimulation
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Washington
Bladder Outlet Obstruction, Multiple Sclerosis
GentleCath™ for Men Intermittent Catheter With FeelClean™ Technology
Male self catherterisng observational study.
- Conditions
- Bladder Outlet Obstruction, Multiple Sclerosis, Cauda Equina Syndrome, Enlarged Prostate With Lower Urinary Tract Symptoms
- Trial name
- NCT05470751
- Testing
- Intermittent self-catheterisation
- Where
- 16 sites in United States, France and 1 more
- Volunteers
- 72 people
- Sponsor
- ConvaTec Inc.
Spinal Cord Injuries, Erectile Dysfunction
Safety and Tolerability of a Novel Implantable Neurostimulator for Ameliorate Erectile Function on Spinal Cord Injured Patients
The main objective of the study is to assess the safety and tolerability of cavernous nerve electrical stimulation in patients with spinal cord injured (SCI) by assessing and measuring complications.
- Trial name
- CAVERSTIM (NCT06347575)
- Testing
- Implantation of the caverStim device
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cervical Spinal Cord Injury
Efficacy of a Brain-Computer Interface Controlled Functional Electrical Stimulation Therapy for Spinal Cord Injury Neurorehabilitation
The study's main goal is to determine the efficacy of a therapy with brain-computer interface controlled functional electrical stimulation for neurorehabilitation of spinal cord injury patients' upper limbs.
- Trial name
- NCT05343130
- Testing
- Brain-Computer Interface
- Where
- Mexico
- Volunteers
- 32 people
- Sponsor
- Instituto Nacional de Rehabilitacion
Syringomyelia
Extracellular Vesicles for the Treatment of Syringomyelia
This is a open-label, single-arm, dose escalation phase I clinical trial. The goal of this clinical trial is to evaluate the safety and preliminary efficacy of Intrathecal injection human umbilical cord-derived mesenchymal…
- Trial name
- NCT07295067
- Testing
- Exosomes group
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Xuanwu Hospital, Beijing
Incomplete Spinal Cord Injury, Transverse Myelitis
Ultrasound Imaging Based Sensing of Human Ankle Motion Intent and Control Strategies for Ankle Assistance
Robotic therapies aim to improve limb function in individuals with neurological injury. Modulation of robotic assistance in many of these therapies is achieved by measuring the extant volitional strength of limb muscles.
- Trial name
- NCT05249595
- Testing
- Surface electromypgraphy-based interface to predict human ankle joint motion intent and use in ankle assistive devices, Ultrasound imaging-based interface to predict human ankle joint motion intent and use in ankle assistive devices, Surface electromypgraphy and ultrasound imaging-based interface to predict human ankle joint motion intent and use in ankle assistive devices
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- North Carolina State University
Spinal Cord Injury
Combined Tibial Nerve Stimulation and Standing for People With SCI
The goal of this clinical trial is to understand how sensory inputs from the lower leg can influence pelvic floor muscle function and urogential function in adults with chronic spinal cord injury (SCI).
- Trial name
- NCT07429305
- Testing
- Standing + Tibial Nerve Stimulation
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of British Columbia
Stroke, Peripheral Neuropathy
Arm Motor Control on Bi and Uni ADLs
This study is being performed to assess how certain chronic disabilities - stroke, upper extremity (UE) amputation, spinal cord injuries (SCI), cerebral palsy (CP) - differ from healthy subjects in their ability to perform ADLs.
- Conditions
- Stroke, Peripheral Neuropathy, Spinal Cord Injuries, Cerebral Palsy
- Trial name
- BiAs (NCT02778529)
- Testing
- Bilateral assessment robots (BiAS)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Spinal Cord Injury
Improving Motor Function After Spinal Cord Injury
The goals of this study are to examine the physiology of Central Nervous System pathways contributing to the control of upper and lower extremity movements after SCI, and to promote the recovery of extremity movements by using…
- Trial name
- NCT01915095
- Testing
- rTMS, Training, Motor Task
- Where
- 3 sites in United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Spinal Cord Injuries
Spinal Cord Injury Program in Exercise
The purpose of this study is to examine two 8-week, remotely delivered exercise interventions: Movement-to-Music (M2M) and Standard Exercise Training (SET), with 327 adults with spinal cord injury.
- Trial name
- SCIPE (NCT03925077)
- Testing
- Movement-to-Music, Standard Exercise Training
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of Alabama at Birmingham
Spinal Cord Injury
Rehabilitation Program for Bladder Control in Individuals With Incomplete Spinal Cord Injury
This prospective, randomized, double-blind clinical trial (with both participants and outcome assessors blinded to group assignments) was carried out at the outpatient clinic of the Faculty of Physical Therapy, Cairo University…
- Trial name
- BCSCI (NCT07008157)
- Testing
- 1. IFC, 2. Timed voiding., motor imagery training
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- Cairo University
Urinary Tract Infections
Prevention of Urinary Tract Infection (UTI) in Persons With Spinal Cord Injury (SCI)
Urinary tract infection (UTI) is the most common infection in patients with spinal cord injury (SCI) and is linked to major undesired results or complications including death.
- Trial name
- NCT00309114
- Testing
- bacterial interference
- Where
- 5 sites in United States
- Volunteers
- 65 people
- Sponsor
- Baylor College of Medicine
Spinal Cord Injuries, Neuropathic Pain
Virtual Walking Intervention for Neuropathic Pain in Spinal Cord Injury
The purpose of this study is to determine if playing a virtual reality walking game can help improve neuropathic pain in adults with chronic spinal cord injury.
- Trial name
- VRWalk (NCT05005026)
- Testing
- VR Game 1, VR Game 2
- Where
- 3 sites in United States, Australia
- Volunteers
- 250 people
- Sponsor
- Texas A&M University
Spinal Cord Injury, Chronic Spinal Cord Injury
First-in-Human Clinical Trial of STUP-001, an In Vivo Direct Cell Conversion Gene Therapy for AIS-A/B Chronic Spinal Cord Injury
This study aim to investigate the safety and exploratory efficacy of STUP-001 which is AAV-based spinal cord injury investigational product.
- Trial name
- STUP-001 (NCT06922890)
- Testing
- STUP-001
- Where
- South Korea
- Volunteers
- 9 people
- Sponsor
- Yonsei University
Spinal Cord Injury
Hypothermia Following Acute Spinal Cord Injury
The purpose of this study is to investigate the long term outcome of patients who receive hypothermia treatment for spinal cord injury.
- Trial name
- NCT01739010
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Miami