Clinical trials: Spinal Cord Injuries and Disorders (SCI/D)
Spinal Cord Injuries and Disorders (SCI/D), Spinal Cord Injury
Motoneuron Recruitment and Motor Evoked Potential Up-Conditioning (MEP) in Spinal Cord Injury (SCI)
The purpose of this research study is to examine the effect of a brain stimulation training to improve the function of brain-spinal cord- muscle connections.
- Trial name
- NCT07179822
- Testing
- Motor Evoked Potential (MEP) Operant Conditioning
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Medical University of South Carolina
Spinal Cord Injuries and Disorders (SCI/D)
Using Non-invasive Brain and Spinal Cord Stimulation to Improve Arm and Hand Function After Spinal Cord Injury
Cervical spinal cord injury (SCI) disrupts communication between the brain and spinal circuits, affecting voluntary movement control and contributing to arm and hand impairments, the top recovery priority for people with…
- Trial name
- NCT07423949
- Testing
- Cerebellar theta burst stimulation, Cervical transcutaneous spinal cord stimulation, Functional task practice
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of British Columbia
Spinal Cord Injury (=3 Years), Sublesional Bone Loss Secondary to SCI
Romosozumab to Improve Bone Mineral Density and Architecture in Chronic SCI
Treatment for sublesional bone loss (osteoporosis) in persons with chronic, motor-complete spinal cord injury (SCI) has been limited and unsuccessful to date.
- Trial name
- Chronic Romo (NCT04232657)
- Testing
- Romosozumab, Denosumab
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Psychological Well-Being, Spinal Cord Injuries
Self-Management Program for AIS D SCI
About 25-51% of adults with acquired spinal cord injury (SCI) have "AIS D" SCI, the lowest severity grade of neurologic injury. Veterans with AIS D SCI generally have better outcomes in mobility, community integration, and…
- Trial name
- SCISM-D (NCT05800717)
- Testing
- SCI Self-Management for AIS D
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Spinal Cord Injuries and Disorders (SCI/D)
Caring Connections: A Program to Alleviate Social Isolation and Loneliness in Individuals Living With Spinal Cord Injury
This study will use a randomized controlled design with an active attention control group to evaluate an intervention intended to reduce social isolation and loneliness in persons with SCI/D.
- Trial name
- NCT05295108
- Testing
- Caring Connections, Attention control
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Chicago Association for Research and Education in Science
Spinal Cord Injury, Vitamin D Deficiency
Vitamin D Deficiency and Replacement on Pulmonary and Endocrine Function in SCI
Studies have shown that individuals who have suffered a spinal cord injury are at an increased risk of Vitamin D deficiency compared to able-bodied individuals.
- Trial name
- NCT02099955
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Spinal Cord Injuries (SCI), Spinal Cord Disease
Enhancing Rehabilitation Participation in Patients With SCI/D Using Motivational Interviewing
The purpose of this multi-site clinical trial is to see whether people with spinal cord injury or disorder (SCI/D) demonstrate higher level of participation in rehabilitation sessions and other outcomes when their therapists are…
- Trial name
- NCT07364773
- Testing
- Motivational Interviewing
- Where
- 3 sites in United States
- Volunteers
- 180 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injuries (SCI), Spinal Cord Injury
mSCI: Mobile Health App for Veterans With SCI and Caregivers
Caregivers of persons with Spinal Cord Injury (SCI) face increased risk of psychological distress, health problems, reduced quality of life, relationship strain, and restrictions in social and work participation.
- Conditions
- Spinal Cord Injuries (SCI), Spinal Cord Injury, Spinal Cord Injuries (Complete and Incomplete), Family Caregivers
- Trial name
- NCT07269977
- Testing
- iMHERE 2.0. A mobile health App designed to support veterans with SCI manage their self care, and their caregivers
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Spinal Cord Injury
Developing a Home Telehealth Program to Manage Pressure Ulcers in SCI/D
The Veteran's Health Administration (VHA) is a national leader in using distance technology to monitor patients' self-care via an in-home messaging device with disease management protocols (DMPs).
- Trial name
- NCT00624806
- Testing
- Daily telephone calls, Weekly telephone calls
- Where
- 2 sites in United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Autonomic Dysreflexia, Spinal Cord Injuries and Disorders (SCI/D)
Cardiac Morphology and Function in Individuals With Autonomic Dysreflexia
This case-control study aims to investigate left ventricular remodeling in individuals with chronic spinal cord injury or disease (SCI/D) (≥10 years) and autonomic dysreflexia (AD) who have no prior cardiovascular history.
- Conditions
- Autonomic Dysreflexia, Spinal Cord Injuries and Disorders (SCI/D), Cardiac Remodeling
- Trial name
- HEART_REMOD_AD (NCT07456722)
- Where
- Switzerland
- Volunteers
- 48 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Incomplete Spinal Cord Injury (SCI), ASIA C and D Classification of SCI
Effect of Hybrid Functional Electrical Stimulation and Augmented Reality-Based Gait Training on Gait Parameters Among Incomplete Spinal Cord Injury Patients
The goal of this clinical trial is to determine whether combining Functional Electrical Stimulation (FES) with Augmented Reality (AR)-based gait training can improve walking ability in individuals with incomplete spinal cord…
- Conditions
- Incomplete Spinal Cord Injury (SCI), ASIA C and D Classification of SCI, Gait Dysfunction
- Trial name
- FES AR SCI (NCT07263581)
- Testing
- Functional Electrical Stimulation (FES) and Augmented Reality (AR), Conventional Overground Gait Training (COGT)
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Sleep Apnea, SCI/D
Effect of Hypercapnia Treatment on Respiratory Recovery After Spinal Cord Injury
It is estimated that 1,275,000 people in the United States alone live with spinal cord injury, including around 100,000 Veterans with spinal cord injury, making the V.A.
- Conditions
- Sleep Apnea, SCI/D, Hypercapnia
- Trial name
- RECOV2SCI (NCT05536076)
- Testing
- Hypercapnia treatment
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- VA Office of Research and Development
Spinal Cord Injury, Spinal Cord Involvement
Clinical Trial of a Serious Game for Individuals With SCI/D
This study will evaluate the efficacy of a newly developed serious game, SCI HARD, to enhance self-management skills, self-reported health behaviors, and quality of life among adolescents and young adults with spinal cord injury…
- Conditions
- Spinal Cord Injury, Spinal Cord Involvement, Spina Bifida, Transverse Myelitis
- Trial name
- NCT02341950
- Testing
- SCI Hard
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- University of Michigan
Spinal Cord Injury, Neurogenic Bladder (NB)
Coupled Gentamicin-Lactobacillus Rhamnosus in NLUTD
The main objective of the proposed research study is to determine in men and women with spinal cord injury/disease and neurogenic bladder whether the dose of coupled gentamicin \& Lactobacillus rhamnosus GG affects the…
- Conditions
- Spinal Cord Injury, Neurogenic Bladder (NB), Neurogenic Lower Urinary Tract Dysfunction, Multiple Sclerosis
- Trial name
- NCT07643974
- Testing
- Gentamicin, Lactobacillus Rhamnosus GG
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- Medstar Health Research Institute