Clinical trials: Spinal Cord Injury(SCI)
Spinal Cord Injury (SCI)
Restoring Walking in Non-ambulatory Children With Severe Chronic Spinal Cord Injury (SCI) (Kids STEP Study)
The Kids STEP Study aims to 1. Determine if walking can be restored in children with incomplete SCI and little to no leg movement 2. Identify the neural pathways that permit recovery of walking
- Trial name
- NCT00488280
- Testing
- Locomotor Training
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Florida
Spinal Cord Injuries
Nutrition Education Program in Spinal Cord Injury (SCI)
The purpose of this research is to assess the effectiveness of a nutrition education program in increasing nutrition knowledge and improving health-related biomarkers in individuals with spinal cord injury (SCI).
- Trial name
- NCT05953597
- Testing
- Nutrition Education
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Miami
Chronic Spinal Cord Injury
Impact of Persistent Conductances on Motor Unit Firing in SCI
This study is being done to measure the differences between the electrical activity of muscles and /single muscle fibers in individuals with long-term spinal cord injury and neurologically intact individuals without spinal cord…
- Trial name
- NCT02136823
- Testing
- sugar pill, Riluzole, Isradipine
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injuries
Health Interventions for Survivors and Primary Support Persons of Spinal Cord Injury
The overall objective of this project is to test the efficacy of an innovative multi-component intervention aimed at reducing the risk for adverse health outcomes among caregivers of older survivors with spinal cord injury or…
- Trial name
- SCI (NCT00148239)
- Testing
- Caregiver Only Intervention, Dual Treatment, Control
- Where
- 2 sites in United States
- Volunteers
- 380 people
- Sponsor
- University of Pittsburgh
Spinal Cord Injuries
Long-term PAS in Rehabilitation After SCI
The investigators have recently shown in two pilot incomplete SCI patients that long-term paired associative stimulation is capable of restoring voluntary control over some paralyzed muscles and enhancing motor output in the weak…
- Trial name
- NCT03045744
- Testing
- long-term paired associative stimulation
- Where
- Finland
- Volunteers
- 5 people
- Sponsor
- Helsinki University Central Hospital
Spinal Cord Injuries
Effects of Breathing Mild Bouts of Low Oxygen on Limb Mobility After Spinal Injury
Accumulating evidence suggests that repeatedly breathing low oxygen levels for brief periods (termed intermittent hypoxia) is a safe and effective treatment strategy to promote meaningful functional recovery in persons with…
- Trial name
- NCT02323945
- Testing
- AIH, Walk, Strength
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Traumatic Spinal Cord Injury, Neuropathic Pain
Biomarkers for Pain in Spinal Cord Injury Patients
The investigators propose to compare plasma protein profiles for SCI patients with/without chronic neuropathic pain in order identify biomarker(s) that are associated with this medical condition.
- Trial name
- SCI Pain (NCT00913471)
- Testing
- blood samples
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Spinal Cord Injury, Sleep Apnea, Obstructive
Sleep-Disordered Breathing in Chronic SCI
The purpose of this study is to examine impact of Sleep Disordered Breathing (SDB) treatment in persons with chronic Spinal Cord Injury (SCI).
- Trial name
- NCT02176928
- Testing
- AutoPAP
- Where
- 4 sites in United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Miami
Spinal Cord Injuries, Physical Disability
Physical Fitness, Exercise Self-efficacy, Physical Activity Level in People With Spinal Cord Injury (SCI)
This is a single blind randomized controlled trial study which will conducted on people with paraplegia wheelchair users. The objectives of this study is to investigates the effects of 16 weeks of 'Graded Exercise Integrated…
- Trial name
- NCT03420170
- Testing
- Graded Exercise Integrated Education, Conventional Physical Therapy
- Volunteers
- 40 people
- Sponsor
- Universiti Teknologi Mara
Spinal Cord Injury
Effect of Prolonged Electrical Stimulation on Neural Plasticity in Spinal Cord Injury
Electrical stimulation (pulses of electricity applied over the skin of your wrist) and activity-based hand exercise have been shown to improve motor skill and strength in individuals with stroke and have recently been shown to…
- Trial name
- NCT00387673
- Testing
- Somatosensory Stimulation and Massed Practice Training
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- VA Office of Research and Development
Spinal Cord Injury
SCI&U Peer Health Coaching Program for Individuals Newly Discharged From Inpatient Rehabilitation
The goal of this clinical trial is to learn if the online program and web-based platform for delivery of self-management services to people with spinal cord injury (SCI) called "SCI \& U" can support transitions from hospital to…
- Trial name
- SCIU2 (NCT06677905)
- Testing
- web-based spinal cord injury self-management program, Peer support
- Where
- 2 sites in United States, Canada
- Volunteers
- 76 people
- Sponsor
- University of Toronto
Spinal Cord Injury
Clinical Evaluation of Instrumented Wheel as Biomedical Device Quantifying the Displacement Efficiency
The purpose of this study is to validate an instrumented wheel such as a new biomedical device. The physicians will compare this instrumented wheel with another instrumentation "Ergometer roller", each patient will try the both…
- Trial name
- FRM (NCT01935687)
- Testing
- Using of instrumented wheel, Using of ergometer roller
- Where
- France
- Volunteers
- 62 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Spinal Cord Injuries
Remote Ischemic Conditioning for PwSCI
The long-term goal of this project is to improve the overall cardiometabolic health of persons with spinal cord injury (SCI). This pilot study will test the feasibility and acceptability of remote ischemic conditioning…
- Trial name
- NCT07488793
- Testing
- RIC high-dose standard blood pressure cuff, RIC high-dose automated blood flow restriction cuff, RIC low-dose standard blood pressure cuff
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Washington University School of Medicine
Spinal Cord Injury, Incomplete Spinal Cord Injury
Tele-rehabilitation Using TDCS Combined with Exercise in People with Spinal Cord Injury
This study aims to explore the effect of trans cranial direct current stimulation (tDCS) combined with self-exercise at home for 1 month training (3 sessions/week, for 4 weeks).
- Trial name
- NCT06079138
- Testing
- Transcranial direct current stimulation (Active), Telerehabilitation exercise
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Mahidol University
Spinal Cord Injury, Chronic Pain
Education Interventions for Self-Management of Pain Post-SCI: A Pilot Study
Chronic pain (pain that is that is present for a long period of time) is very common among people with spinal cord injury (SCI). Unfortunately, chronic pain is very difficult to treat.
- Trial name
- NCT02262234
- Testing
- Education Program Type 1, Education Program Type 2
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Kessler Foundation
Neurogenic Detrusor Overactivity, Spinal Cord Injury
Treatment of Neurogenic Detrusor Overactivity: Early Versus Late Pudendal Nerve Stimulation in Spinal Cord Injury (SCI) Patients
Background: Although a small group, special attention has to be given to lower urinary tract (LUT) dysfunctions in spinal cord injury (SCI) patients, as they also suffer under a loss of motor-sensory function and autonomic…
- Trial name
- NCT01043848
- Testing
- external electric pudendal nerve stimulation
- Where
- 3 sites in Spain, Switzerland
- Sponsor
- Ulrich Mehnert
Spinal Cord Injuries and Disorders (SCI/D)
Using Non-invasive Brain and Spinal Cord Stimulation to Improve Arm and Hand Function After Spinal Cord Injury
Cervical spinal cord injury (SCI) disrupts communication between the brain and spinal circuits, affecting voluntary movement control and contributing to arm and hand impairments, the top recovery priority for people with…
- Trial name
- NCT07423949
- Testing
- Cerebellar theta burst stimulation, Cervical transcutaneous spinal cord stimulation, Functional task practice
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of British Columbia
Spinal Cord Injury (SCI)
Interdisciplinary Value-based Cognitive Behavioral Treatment for People With Traumatic Spinal Cord Injury
The goal of this clinical trial is to address the critical need for effective interventions by developing and testing an interdisciplinary values-based cognitive behavioral therapy (V-CBT) program for individuals with spinal cord…
- Trial name
- VALIANT (NCT06599632)
- Testing
- Values-based Cognitive Behavioral Therapy (V-CBT)
- Where
- Denmark
- Volunteers
- 6 people
- Sponsor
- University of Southern Denmark
Spinal Cord Injury
Cardiovascular, Cerebrovascular, and Cognitive Function in Spinal Cord Injury
Increased life expectancy in individuals with spinal cord injury (SCI) present clinicians with the challenge of managing the secondary complications of SCI with the chronic diseases common in an aging population.
- Trial name
- NCT02122991
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Spinal Cord Injuries, Obesity
The SEEA (SCI Energy Expenditure and Activity) Study
People with SCI are at higher risk of obesity and chronic diseases, such as hypertension, high cholesterol, diabetes and cardiovascular disease, than the general population.
- Conditions
- Spinal Cord Injuries, Obesity, Metabolic Syndrome, Cardiovascular Diseases
- Trial name
- SEEA (NCT04748835)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Baylor Research Institute